Citation Impact
Citing Papers
Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases
2006
ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation
2009 StandoutScience
High-fat diets cause insulin resistance despite an increase in muscle mitochondria
2008
Dendritic cell–expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice
2007 StandoutNobel
Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity
2013 Standout
Regulation of Insulin Secretion by SIRT4, a Mitochondrial ADP-ribosyltransferase
2007
Design, synthesis and biological characterization of novel inhibitors of CD38
2011
Sirtuins as regulators of metabolism and healthspan
2012 Standout
Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer
2012
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
2009 StandoutNature
Influence of Insulin in the Ventromedial Hypothalamus on Pancreatic Glucagon Secretion In Vivo
2010
NAD+-dependent deacetylation of H4 lysine 16 by class III HDACs
2007
ω-6 Polyunsaturated fatty acids extend life span through the activation of autophagy
2013 StandoutNobel
Mitochondrial uncoupling and lifespan
2010
Skin-specific Deletion of Stearoyl-CoA Desaturase-1 Alters Skin Lipid Composition and Protects Mice from High Fat Diet-induced Obesity
2009
Metabolite of SIR2 Reaction Modulates TRPM2 Ion Channel
2006
SIRT6 protects against pathological damage caused by diet‐induced obesity
2009
SIRT1 Deacetylates and Positively Regulates the Nuclear Receptor LXR
2007
Telomerase Reverse Transcriptase Delays Aging in Cancer-Resistant Mice
2008
Fast, sensitive and accurate integration of single-cell data with Harmony
2019 Standout
Brown and beige fat: development, function and therapeutic potential
2013 Standout
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Sirtuins in Aging and Age-Related Disease
2006
Deacetylation of cortactin by SIRT1 promotes cell migration
2008
Autophagy and the Integrated Stress Response
2010 Standout
Restoration of tubular epithelial cells during repair of the postischemic kidney occurs independently of bone marrow-derived stem cells
2005
Sirtuin-7 Inhibits the Activity of Hypoxia-inducible Factors
2013 StandoutNobel
DAF-16 employs the chromatin remodeller SWI/SNF to promote stress resistance and longevity
2013 StandoutNobel
The genetics of ageing
2010 StandoutNature
Endocrine regulation of ageing
2007
Systemic Transforming Growth Factor-??1 Gene Therapy Induces Foxp3+ Regulatory Cells, Restores Self-Tolerance, and Facilitates Regeneration Of Beta Cell Function in Overtly Diabetic Nonobese Diabetic Mice
2005
Sphingolipids and their metabolism in physiology and disease
2017 Standout
New sources of pancreatic β-cells
2005
Cellular senescence in aging and age-related disease: from mechanisms to therapy
2015 Standout
Hallmarks of aging: An expanding universe
2023 Standout
Cellular pathophysiology of ischemic acute kidney injury
2011 Standout
Hepatic insulin signalling is dispensable for suppression of glucose output by insulin in vivo
2015
Mesenchymal stem cells in health and disease
2008 Standout
SirT1 Inhibition Reduces IGF-I/IRS-2/Ras/ERK1/2 Signaling and Protects Neurons
2008
Mammalian sirtuins—emerging roles in physiology, aging, and calorie restriction
2006
Conserved Metabolic Regulatory Functions of Sirtuins
2008
Nucleocytoplasmic Shuttling of the NAD+-dependent Histone Deacetylase SIRT1
2007
The NAD World: A New Systemic Regulatory Network for Metabolism and Aging—Sirt1, Systemic NAD Biosynthesis, and Their Importance
2009
Nampt/PBEF/Visfatin Regulates Insulin Secretion in β Cells as a Systemic NAD Biosynthetic Enzyme
2007
Glucose Restriction Inhibits Skeletal Myoblast Differentiation by Activating SIRT1 through AMPK-Mediated Regulation of Nampt
2008
High Glucose Induced Alteration of SIRTs in Endothelial Cells Causes Rapid Aging in a p300 and FOXO Regulated Pathway
2013
Age‐associated loss of Sirt1‐mediated enhancement of glucose‐stimulated insulin secretion in beta cell‐specific Sirt1‐overexpressing (BESTO) mice
2007
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Cellular senescence in ageing: from mechanisms to therapeutic opportunities
2020 Standout
PARP-2 Regulates SIRT1 Expression and Whole-Body Energy Expenditure
2011
Adipokines in inflammation and metabolic disease
2011 Standout
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Evidence against a Physiologic Role for Acute Changes in CNS Insulin Action in the Rapid Regulation of Hepatic Glucose Production
2012
Unraveling the Regulation of Hepatic Metabolism by Insulin
2017
SirT1 Gain of Function Increases Energy Efficiency and Prevents Diabetes in Mice
2008
The Impact of the Gut Microbiota on Human Health: An Integrative View
2012 Standout
Autophagy in Human Health and Disease
2013 Standout
SIRT1: recent lessons from mouse models
2010
Group VIA Ca2+-independent phospholipase A2 (iPLA2β) and its role in β-cell programmed cell death
2010
Recent progress in the biology and physiology of sirtuins
2009 Nature
Nutritional stress in eukaryotic cells: Oxidative species and regulation of survival in time of scarceness
2011
Interphase Nucleo-Cytoplasmic Shuttling and Localization of SIRT2 during Mitosis
2007
Hematopoietic Stem-Cell Transplantation
2006 Standout
The Emerging Hallmarks of Cancer Metabolism
2016 Standout
PTEN Deletion and Concomitant c-Myc Activation Do Not Lead to Tumor Formation in Pancreatic β Cells
2008 StandoutNobel
Autophagy and Aging
2011 Standout
SRT1720, SRT2183, SRT1460, and Resveratrol Are Not Direct Activators of SIRT1
2010
How does SIRT1 affect metabolism, senescence and cancer?
2008
SirT1-null mice develop tumors at normal rates but are poorly protected by resveratrol
2009
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
The telomerase activator TA‐65 elongates short telomeres and increases health span of adult/old mice without increasing cancer incidence
2011
Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability
2009 Standout
Targeting Sirtuin 1 to Improve Metabolism: All You Need Is NAD+?
2011
Insulin Secretory Responses and Phospholipid Composition of Pancreatic Islets from Mice That Do Not Express Group VIA Phospholipase A2 and Effects of Metabolic Stress on Glucose Homeostasis
2006
The Hallmarks of Aging
2013 Standout
Biochemical characterization, localization, and tissue distribution of the longer form of mouse SIRT3
2009
SIRT4 Inhibits Glutamate Dehydrogenase and Opposes the Effects of Calorie Restriction in Pancreatic β Cells
2006
Nicotinamide Mononucleotide, a Key NAD+ Intermediate, Treats the Pathophysiology of Diet- and Age-Induced Diabetes in Mice
2011
Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication
2018 Standout
SirT1 Regulates Energy Metabolism and Response to Caloric Restriction in Mice
2008
Roles and regulation of neutral sphingomyelinase-2 in cellular and pathological processes
2014
Exercise-induced Mitochondrial Biogenesis Begins before the Increase in Muscle PGC-1α Expression
2006
SIRT1 Improves Insulin Sensitivity under Insulin-Resistant Conditions by Repressing PTP1B
2007
Neutrophil recruitment and function in health and inflammation
2013 Standout
SIRT1 transgenic mice show phenotypes resembling calorie restriction
2007
Endothelial Progenitor Cells and Vascular Biology in Diabetes Mellitus: Current Knowledge and Future Perspectives
2005
Fasting-dependent glucose and lipid metabolic response through hepatic sirtuin 1
2007
Dendritic cells with TGF-β1 differentiate naïve CD4+CD25−T cells into islet-protective Foxp3+regulatory T cells
2007 StandoutNobel
The Biochemistry of Sirtuins
2006
X-Box Binding Protein 1 Is Essential for Insulin Regulation of Pancreatic α-Cell Function
2013
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
Sirtuin 1 and Sirtuin 3: Physiological Modulators of Metabolism
2012
Treatment of severe autoimmune disease by stem-cell transplantation
2005 Nature
Mesenchymal Stem Cells Cooperate with Bone Marrow Cells in Therapy of Diabetes
2007
Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis
2015 StandoutNobel
Impaired Insulin Action Is Associated With Increased Glucagon Concentrations in Nondiabetic Humans
2017
Sirtuins in mammals: insights into their biological function
2007
Sirt1 protects against high-fat diet-induced metabolic damage
2008
Chromone: A Valid Scaffold in Medicinal Chemistry
2014 Standout
Sirtuins, a key regulator of ageing and age-related neurodegenerative diseases
2022
Clinical and Experimental Pancreatic Islet Transplantation to Striated Muscle
2010
Mammalian Sirtuins: Biological Insights and Disease Relevance
2010 Standout
Fiber Types in Mammalian Skeletal Muscles
2011 Standout
Osmosensory signaling in Mycobacterium tuberculosis mediated by a eukaryotic-like Ser/Thr protein kinase
2013 StandoutNobel
Four faces of cellular senescence
2011 Standout
Signaling Properties of CD38 in the Mouse Immune System: Enzyme-dependent and -independent Roles in Immunity
2006
Intermittent fasting preserves beta-cell mass in obesity-induced diabetes via the autophagy-lysosome pathway
2017
The enzyme CD38 (a NAD glycohydrolase, EC 3.2.2.5) is necessary for the development of diet‐induced obesity
2007
Mechanisms of Diabetic Complications
2013 Standout
Somatostatin and insulin mediate glucose-inhibited glucagon secretion in the pancreatic α-cell by lowering cAMP
2014
Essential Role of Pten in Body Size Determination and Pancreatic β-Cell Homeostasis In Vivo
2006 StandoutNobel
Host-Gut Microbiota Metabolic Interactions
2012 StandoutScience
mTOR: a pharmacologic target for autophagy regulation
2015 Standout
Adenoviral transfer of HIF-1α enhances vascular responses to critical limb ischemia in diabetic mice
2009 StandoutNobel
Phospholipase A2Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention
2011 Standout
Bone marrow mesenchymal stem cells express a restricted set of functionally active chemokine receptors capable of promoting migration to pancreatic islets
2005
Sirtuins — novel therapeutic targets to treat age-associated diseases
2008
Fidarestat improves cardiomyocyte contractile function in db/db diabetic obese mice through a histone deacetylase Sir2-dependent mechanism
2007
Minireview: Autophagy in Pancreatic β-Cells and Its Implication in Diabetes
2015
Development of autophagy inducers in clinical medicine
2015
Leptin therapy improves insulin-deficient type 1 diabetes by CNS-dependent mechanisms in mice
2010
Regulation of Mammalian Autophagy in Physiology and Pathophysiology
2010 Standout
The Secret Life of NAD+: An Old Metabolite Controlling New Metabolic Signaling Pathways
2010
Works of Eric L. Ford being referenced
Autophagy Regulates Pancreatic Beta Cell Death in Response to Pdx1 Deficiency and Nutrient Deprivation
2009
Targeted Ablation of Glucose-dependent Insulinotropic Polypeptide-producing Cells in Transgenic Mice Reduces Obesity and Insulin Resistance Induced by a High Fat Diet
2008
Increased dosage of mammalian Sir2 in pancreatic β cells enhances glucose-stimulated insulin secretion in mice
2005
Real-time, multidimensional in vivo imaging used to investigate blood flow in mouse pancreatic islets
2008
Spontaneous Development of Endoplasmic Reticulum Stress That Can Lead to Diabetes Mellitus Is Associated with Higher Calcium-independent Phospholipase A2 Expression
2009
Insulin Signaling in α Cells Modulates Glucagon Secretion In Vivo
2009
Calpain System Regulates Muscle Mass and Glucose Transporter GLUT4 Turnover
2004
Suppressed Insulin Signaling and Increased Apoptosis inCd38-Null Islets
2006
Recruitment of Bone Marrow-Derived Endothelial Cells to Sites of Pancreatic β-Cell Injury
2004