Citation Impact
Citing Papers
TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis
2008 StandoutScience
Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase
2004 StandoutScience
Pathological α-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
2012 StandoutScience
Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant Motor Neurons in ALS Mice
2003 Science
Parkinson-like syndrome induced by continuous MPTP infusion: Convergent roles of the ubiquitin-proteasome system and α-synuclein
2005 StandoutNobel
Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons
2008 StandoutScience
Onset and Progression in Inherited ALS Determined by Motor Neurons and Microglia
2006 StandoutScience
Designing siRNA That Distinguish between Genes That Differ by a Single Nucleotide
2006
Antioxidant Therapy: A New Pharmacological Approach in Shock, Inflammation, and Ischemia/Reperfusion Injury
2001
Proteasomal inhibition causes the formation of protein aggregates containing a wide range of proteins, including nitrated proteins
2003
Small-Molecule Inhibitors of the p53-MDM2 Interaction
2010
Toxicity of Familial ALS-Linked SOD1 Mutants from Selective Recruitment to Spinal Mitochondria
2004
Apoptosis in the nervous system
2000 StandoutNature
The physiology and pathophysiology of nitric oxide in the brain
2005
The Value of Transgenic Models for the Study of Neurodegenerative Diseases
2000
The Ubiquitin Proteasome System in Neurodegenerative Diseases
2003 StandoutNobel
Ferroptosis as a p53-mediated activity during tumour suppression
2015 StandoutNature
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
2003 StandoutNobel
The Role of Autophagy, Mitophagy and Lysosomal Functions in Modulating Bioenergetics and Survival in the Context of Redox and Proteotoxic Damage: Implications for Neurodegenerative Diseases
2016
Effects of metalloporphyrin catalytic antioxidants in experimental brain ischemia
2002
Pathobiology of ischaemic stroke: an integrated view
1999 Standout
Calcium, ATP, and ROS: a mitochondrial love-hate triangle
2004 Standout
The genetic and molecular mechanisms of motor neuron disease
1998
Superoxide dismutase and the death of motoneurons in ALS
2001
Glial cells as intrinsic components of non-cell-autonomous neurodegenerative disease
2007
Increased 3‐nitrotyrosine and oxidative damage in mice with a human copper/zinc superoxide dismutase mutation
1997
Mutant Superoxide Dismutase 1 Forms Aggregates in the Brain Mitochondrial Matrix of Amyotrophic Lateral Sclerosis Mice
2005
A role for mitochondria in NLRP3 inflammasome activation
2010 StandoutNature
ALS: A Disease of Motor Neurons and Their Nonneuronal Neighbors
2006
From charcot to lou gehrig: deciphering selective motor neuron death in als
2001
VEGF: necessary to prevent motoneuron degeneration, sufficient to treat ALS?
2004
The neurobiology of zinc in health and disease
2005 Standout
Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke
2000 Standout
Superoxide Anion Radical (O·2), Superoxide Dismutases, and Related Matters
1997
Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress
2002 StandoutNature
Sirt3 Mediates Reduction of Oxidative Damage and Prevention of Age-Related Hearing Loss under Caloric Restriction
2010
Proteasomal inhibition by misfolded mutant superoxide dismutase 1 induces selective motor neuron death in familial amyotrophic lateral sclerosis
2002
Manganese superoxide dismutase in disease
2001
Oxidative stress in septic shock and disseminated intravascular coagulation
2002
Mutant Cu/Zn-Superoxide Dismutase Proteins Have Altered Solubility and Interact with Heat Shock/Stress Proteins in Models of Amyotrophic Lateral Sclerosis
2001
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
Up‐Regulation of Protein Chaperones Preserves Viability of Cells Expressing Toxic Cu/Zn‐Superoxide Dismutase Mutants Associated with Amyotrophic Lateral Sclerosis
1999
Decoding ALS: from genes to mechanism
2016 StandoutNature
β-Lactam antibiotics offer neuroprotection by increasing glutamate transporter expression
2005 StandoutNature
Oxidative stress in neurodegenerative diseases: therapeutic implications for superoxide dismutase mimetics
2003
Oxidative stress mechanisms and potential therapeutics in Alzheimer disease
2004
Amyotrophic Lateral Sclerosis
2001
Using Mouse Models to Explore MDM-p53 Signaling in Development, Cell Growth, and Tumorigenesis
2012
Life in extreme environments
2001 StandoutNature
Virus‐delivered small RNA silencing sustains strength in amyotrophic lateral sclerosis
2005
Lack of involvement of neuronal nitric oxide synthase in the pathogenesis of a transgenic mouse model of familial amyotrophic lateral sclerosis
1999
Angiogenesis in life, disease and medicine
2005 StandoutNature
Aquaporins in the central nervous system
2001
Widespread changes in protein synthesis induced by microRNAs
2008 StandoutNature
Truncated wild-type SOD1 and FALS-linked mutant SOD1 cause neural cell death in the chick embryo spinal cord
2005
Nopp 140 shuttles on tracks between nucleolus and cytoplasm
1992 StandoutNobel
Selective silencing by RNAi of a dominant allele that causes amyotrophic lateral sclerosis
2003
Chapter 19 Role of endogenous nitric oxide and peroxynitrite formation in the survival and death of motor neurons in culture
1998
Oxidants, oxidative stress and the biology of ageing
2000 StandoutNature
Neurotoxic in vivo models of Parkinson’s disease
2010
The Proteasome
2001
Elevation of the Hsp70 chaperone does not effect toxicity in mouse models of familial amyotrophic lateral sclerosis
2005
Loss of autophagy in the central nervous system causes neurodegeneration in mice
2006 StandoutNature
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
2006 StandoutNature
Reactive oxygen species have a causal role in multiple forms of insulin resistance
2006 StandoutNature
Mitochondrial Reactive Oxygen Species in Mice Lacking Superoxide Dismutase 2
2005
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
Reactive oxygen species, antioxidants, and the mammalian thioredoxin system1 1This review is based on the licentiate thesis “Thioredoxin reductase—interactions with the redox active compounds 1-chloro-2,4-dinitrobenzene and lipoic acid” by Jonas Nordberg, 2001, Karolinska Institute, Stockholm, ISBN 91-631-1064-4.
2001 Standout
Metallothionein Expression Is Altered in a Transgenic Murine Model of Familial Amyotrophic Lateral Sclerosis
2000
Slowing of axonal transport is a very early event in the toxicity of ALS–linked SOD1 mutants to motor neurons
1999
Revealing the world of RNA interference
2004 StandoutNatureNobel
ALS-Linked SOD1 Mutant G85R Mediates Damage to Astrocytes and Promotes Rapidly Progressive Disease with SOD1-Containing Inclusions
1997 Standout
In vivo peroxidative activity of FALS-mutant human CuZnSODs expressed in yeast
2002
Dorfin Localizes to the Ubiquitylated Inclusions in Parkinson's Disease, Dementia with Lewy Bodies, Multiple System Atrophy, and Amyotrophic Lateral Sclerosis
2003
The Hallmarks of Aging
2013 Standout
Focal dysfunction of the proteasome: a pathogenic factor in a mouse model of amyotrophic lateral sclerosis
2004
Benefit of a combined treatment with trientine and ascorbate in familial amyotrophic lateral sclerosis model mice
1999
Oxidative stress in ALS: A mechanism of neurodegeneration and a therapeutic target
2006
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Oxidative stress and nitration in neurodegeneration: Cause, effect, or association?
2003
Molecular biology of amyotrophic lateral sclerosis: insights from genetics
2006
Gain in functions of mutant Cu,Zn-superoxide dismutases as a causative factor in familial amyotrophic lateral sclerosis: Less reactive oxidant formation but high spontaneous aggregation and precipitation
2000
CuZn superoxide dismutase (SOD1) accumulates in vacuolated mitochondria in transgenic mice expressing amyotrophic lateral sclerosis-linked SOD1 mutations
2001
Amyotrophic Lateral Sclerosis
2001 Standout
Dorfin Ubiquitylates Mutant SOD1 and Prevents Mutant SOD1-mediated Neurotoxicity
2002
Reduction of metallothioneins promotes the disease expression of familial amyotrophic lateral sclerosis mice in a dose‐dependent manner
2001
Prolyl Hydroxylase Domain Inhibitors: A Route to HIF Activation and Neuroprotection
2009
A constitutive promoter directs expression of the nerve growth factor receptor gene.
1988
Conversion to the amyotrophic lateral sclerosis phenotype is associated with intermolecular linked insoluble aggregates of SOD1 in mitochondria
2006
Postischemic Application of Lipid Peroxidation Inhibitor U-101033E Reduces Neuronal Damage After Global Cerebral Ischemia in Rats
1998
Mitochondrial Susceptibility to Oxidative Stress Exacerbates Cerebral Infarction That Follows Permanent Focal Cerebral Ischemia in Mutant Mice with Manganese Superoxide Dismutase Deficiency
1998
Amyotrophic lateral sclerosis: A proposed mechanism
2002
An α-syntrophin-dependent pool of AQP4 in astroglial end-feet confers bidirectional water flow between blood and brain
2003 StandoutNobel
Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
1997 Standout
Neurexin III alpha: extensive alternative splicing generates membrane-bound and soluble forms.
1993 StandoutNobel
The Free Radical Theory of Aging Matures
1998 Standout
Overexpression of SOD1 in Transgenic Rats Protects Vulnerable Neurons Against Ischemic Damage After Global Cerebral Ischemia and Reperfusion
1998
Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS)
2002
Formation of high molecular weight complexes of mutant Cu,Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis
2000
Inhibition of Poly(ADP-Ribose) Polymerase
1998
Manganese Superoxide Dismutase Deficiency Exacerbates Cerebral Infarction After Focal Cerebral Ischemia/Reperfusion in Mice
2002
Neuron-Specific Expression of Mutant Superoxide Dismutase 1 in Transgenic Mice Does Not Lead to Motor Impairment
2001
Chaperone-facilitated copper binding is a property common to several classes of familial amyotrophic lateral sclerosis-linked superoxide dismutase mutants
1998
Misfolded CuZnSOD and amyotrophic lateral sclerosis
2003
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Extracellular superoxide dismutase deficiency worsens outcome from focal cerebral ischemia in the mouse
1999
DAF-16 Target Genes That Control C. elegans Life-Span and Metabolism
2003 StandoutScienceNobel
Oxidative stress and nitration in neurodegeneration: Cause, effect, or association?
2003
Superoxide dismutase and neurofilament transgenic models of amyotrophic lateral sclerosis
1998
From Charcot to SOD1
1999
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
Superoxide dismutase and the death of motoneurons in ALS
2001
Mitochondrial Diseases in Man and Mouse
1999 StandoutScience
An analysis of vertebrate mRNA sequences: intimations of translational control.
1991 Standout
Mitochondrial damage due to SOD1 deficiency in SH‐SY5Y neuroblastoma cells: a rationale for the redundancy of SOD1
2006
Role of Endothelial Nitric Oxide Generation and Peroxynitrite Formation in Reperfusion Injury After Focal Cerebral Ischemia
2000
Caspase-1 is activated in neural cells and tissue with amyotrophic lateral sclerosis-associated mutations in copper-zinc superoxide dismutase
1998
Cytosolic Redistribution of Cytochrome C after Transient Focal Cerebral Ischemia in Rats
1998
Ischemic Cell Death in Brain Neurons
1999 Standout
Increased mitochondrial oxidative stress in the Sod2 (+/−) mouse results in the age-related decline of mitochondrial function culminating in increased apoptosis
2001
Delayed K + clearance associated with aquaporin-4 mislocalization: Phenotypic defects in brains of α-syntrophin-null mice
2003 StandoutNobel
Manganese Superoxide Dismutase Mediates the Early Release of Mitochondrial Cytochrome C and Subsequent DNA Fragmentation after Permanent Focal Cerebral Ischemia in Mice
1999
Bradykinin B1 and B2 receptors both have protective roles in renal ischemia/reperfusion injury
2007 StandoutNobel
Bioavailable copper modulates oxidative phosphorylation and growth of tumors
2013
Mitochondrial disease in superoxide dismutase 2 mutant mice
1999
Disease Progression in a Transgenic Model of Familial Amyotrophic Lateral Sclerosis Is Dependent on Both Neuronal and Non-Neuronal Zinc Binding Proteins
2002
UNRAVELING THE MECHANISMS INVOLVED IN MOTOR NEURON DEGENERATION IN ALS
2004
Delayed onset of brain edema and mislocalization of aquaporin-4 in dystrophin-null transgenic mice
2002 StandoutNobel
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
Restricted Expression of G86R Cu/Zn Superoxide Dismutase in Astrocytes Results in Astrocytosis But Does Not Cause Motoneuron Degeneration
2000
Copper chaperone for superoxide dismutase is essential to activate mammalian Cu/Zn superoxide dismutase
2000
COPPER-ZINC SUPEROXIDE DISMUTASE AND AMYOTROPHIC LATERAL SCLEROSIS
2003
Elevated free nitrotyrosine levels, but not protein-bound nitrotyrosine or hydroxyl radicals, throughout amyotrophic lateral sclerosis (ALS)-like disease implicate tyrosine nitration as an aberrant in vivo property of one familial ALS-linked superoxide dismutase 1 mutant
1997
Aquaporin-4 square array assembly: Opposing actions of M1 and M23 isoforms
2003 StandoutNobel
Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1
1998 Science
Works of Eric K. Hoffman being referenced
Superoxide-Mediated Cytotoxicity in Superoxide Dismutase-Deficient Fetal Fibroblasts
1997
Structure and Organization of Amplified DNA on Double Minutes Containing the mdm2 Oncogene
1993
Hindlimb Motor Neurons Require Cu/Zn Superoxide Dismutase for Maintenance of Neuromuscular Junctions
1999
Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury
1996
A novel transferrin/TfR2-mediated mitochondrial iron transport system is disrupted in Parkinson's disease
2009
Targeted Deletion of the Cytosolic Cu/Zn-Superoxide Dismutase Gene (<i>Sod1</i>) Increases Susceptibility to Noise-Induced Hearing Loss
1999
Proteasome inhibition enhances the stability of mouse CuZn superoxide dismutase with mutations linked to familial amyotrophic lateral sclerosis
1996
Structural and Functional Characterization of the Promoter Region of the Mouse c-Ki-ras Gene
1987
Reduction of CuZn-Superoxide Dismutase Activity Exacerbates Neuronal Cell Injury and Edema Formation after Transient Focal Cerebral Ischemia
1997