Citation Impact
Citing Papers
Oxidative Stress
2017 Standout
Distinct Roles of Autophagy in the Heart During Ischemia and Reperfusion
2007
Global phosphorylation analysis of β-arrestin–mediated signaling downstream of a seven transmembrane receptor (7TMR)
2010 StandoutNobel
Hippo signaling disruption and Akt stimulation of ovarian follicles for infertility treatment
2013 Standout
Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3
2015 Standout
The Hippo pathway effector YAP is a critical regulator of skeletal muscle fibre size
2015
Sirtuins as regulators of metabolism and healthspan
2012 Standout
International regulatory landscape and integration of corrective genome editing into in vitro fertilization
2014
SIRT1: Regulation of longevity via autophagy
2009
A Redox-Dependent Pathway for Regulating Class II HDACs and Cardiac Hypertrophy
2008
Exercise-Induced Oxidative Stress: Cellular Mechanisms and Impact on Muscle Force Production
2008 Standout
Sirtuin-7 Inhibits the Activity of Hypoxia-inducible Factors
2013 StandoutNobel
The genetics of ageing
2010 StandoutNature
The NLRP3 inflammasome: molecular activation and regulation to therapeutics
2019 Standout
Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche
2011 StandoutNobel
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
Nanoparticle therapeutics: an emerging treatment modality for cancer
2008 Standout
Molecular distinction between physiological and pathological cardiac hypertrophy: Experimental findings and therapeutic strategies
2010
Modulation of oxidative stress as an anticancer strategy
2013 Standout
SirT1 Inhibition Reduces IGF-I/IRS-2/Ras/ERK1/2 Signaling and Protects Neurons
2008
Thiol-based mechanisms of the thioredoxin and glutaredoxin systems: implications for diseases in the cardiovascular system
2006
Cardiac autophagy is a maladaptive response to hemodynamic stress
2007 Standout
Identification of BRCA1-IRIS, a BRCA1 locus product
2004
From Sirtuin Biology to Human Diseases: An Update
2012
Compartment-specific Control of Reactive Oxygen Species Scavenging by Antioxidant Pathway Enzymes
2016
Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer
2015 Standout
Toward a new STATe: The role of STATs in mitochondrial function
2014
ROS Function in Redox Signaling and Oxidative Stress
2014 Standout
Combined targeting of perivascular and endothelial tumor cells enhances anti-tumor efficacy of liposomal chemotherapy in neuroblastoma
2010
Yes-associated Protein Isoform 1 (Yap1) Promotes Cardiomyocyte Survival and Growth to Protect against Myocardial Ischemic Injury
2012
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice
2012
Effects of thioredoxin reductase-1 deletion on embryogenesis and transcriptome
2007 StandoutNobel
Autophagy in the Pathogenesis of Disease
2008 Standout
Redox regulation of FoxO transcription factors
2015
Redox-based regulation of signal transduction: Principles, pitfalls, and promises
2008
Mitochondrial SIRT3 and heart disease
2010
Emerging paradigms of β-arrestin-dependent seven transmembrane receptor signaling
2011 StandoutNobel
Autophagy in Human Health and Disease
2013 Standout
SIRT1: recent lessons from mouse models
2010
Growth Differentiation Factor 11 Is a Circulating Factor that Reverses Age-Related Cardiac Hypertrophy
2013 Standout
Methods in Mammalian Autophagy Research
2010 Standout
Thioredoxin: a multifunctional antioxidant enzyme in kidney, heart and vessels
2005
Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology
2022 Standout
AKT/PKB Signaling: Navigating the Network
2017 Standout
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
2011 Standout
Autophagy: process and function
2007 Standout
The Hallmarks of Aging
2013 Standout
Liposomal drug delivery systems: From concept to clinical applications
2012 Standout
Revisiting STAT3 signalling in cancer: new and unexpected biological functions
2014 Standout
Transcriptional control of mitochondrial biogenesis: the central role of PGC-1
2008
Quantitative Phosphoproteomics Dissection of Seven-transmembrane Receptor Signaling Using Full and Biased Agonists
2010
Exogenous NAD Blocks Cardiac Hypertrophic Response via Activation of the SIRT3-LKB1-AMP-activated Kinase Pathway
2009
Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity
2014 Nature
Modeling neurodevelopmental disorder-associated humanAGO1mutations inCaenorhabditis elegansArgonautealg-1
2024 StandoutNobel
Forkhead Homeobox Type O Transcription Factors in the Responses to Oxidative Stress
2010
Thioredoxins, Glutaredoxins, and Peroxiredoxins—Molecular Mechanisms and Health Significance: from Cofactors to Antioxidants to Redox Signaling
2013
Role of Thioredoxin in Cell Growth Through Interactions with Signaling Molecules
2006
Physiological Implications of Hydrogen Sulfide: A Whiff Exploration That Blossomed
2012 Standout
Sirt7 Increases Stress Resistance of Cardiomyocytes and Prevents Apoptosis and Inflammatory Cardiomyopathy in Mice
2008
Targeted Deletion of Thioredoxin-Interacting Protein Regulates Cardiac Dysfunction in Response to Pressure Overload
2007
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
The Deacetylase SIRT1 Promotes Membrane Localization and Activation of Akt and PDK1 During Tumorigenesis and Cardiac Hypertrophy
2011
Heat shock proteins: Biological functions, pathological roles, and therapeutic opportunities
2022
Hippo signaling impedes adult heart regeneration
2013
Selective Tumor Cell Targeting Using Low-Affinity, Multivalent Interactions
2007
Control of inositol 1,4,5-trisphosphate-induced Ca2+ release by cytosolic Ca2+
1995 Standout
Cytoplasmic Thioredoxin Reductase Is Essential for Embryogenesis but Dispensable for Cardiac Development
2005
Sirtuin 1 and Sirtuin 3: Physiological Modulators of Metabolism
2012
2011 ACCF/AHA Guideline for the Diagnosis and Treatment of Hypertrophic Cardiomyopathy
2011 Standout
YAP1, the nuclear target of Hippo signaling, stimulates heart growth through cardiomyocyte proliferation but not hypertrophy
2012
Sirt1 protects against high-fat diet-induced metabolic damage
2008
Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release
2014 Standout
Signal transduction by reactive oxygen species
2011 Standout
Chromone: A Valid Scaffold in Medicinal Chemistry
2014 Standout
Redox Signaling in Cardiac Physiology and Pathology
2012
SIRT3 Is a Stress-Responsive Deacetylase in Cardiomyocytes That Protects Cells from Stress-Mediated Cell Death by Deacetylation of Ku70
2008
Hippo Pathway Inhibits Wnt Signaling to Restrain Cardiomyocyte Proliferation and Heart Size
2011 Science
Downregulation of Apoptosis-Inducing Factor in Harlequin Mutant Mice Sensitizes the Myocardium to Oxidative Stress–Related Cell Death and Pressure Overload–Induced Decompensation
2005
On PAR with PARP: cellular stress signaling through poly(ADP-ribose) and PARP-1
2012 Standout
Spermidine in health and disease
2018 StandoutScience
Adopt a moratorium on heritable genome editing
2019 StandoutNatureNobel
Sir2 mediates apoptosis through JNK-dependent pathways in Drosophila
2008
Nanoparticle Size and Surface Chemistry Determine Serum Protein Adsorption and Macrophage Uptake
2011 Standout
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
2018 StandoutNobel
On the pivotal role of PPARa in adaptation of the heart to hypoxia and why fat in the diet increases hypoxic injury
2016 StandoutNobel
Activation of the AMPK-FOXO3 Pathway Reduces Fatty Acid–Induced Increase in Intracellular Reactive Oxygen Species by Upregulating Thioredoxin
2009
Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy
2016 Standout
Sirtuins — novel therapeutic targets to treat age-associated diseases
2008
Myocardial AKT: The Omnipresent Nexus
2011
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Cardiac-Specific YAP Activation Improves Cardiac Function and Survival in an Experimental Murine MI Model
2014
Regulation of Mammalian Autophagy in Physiology and Pathophysiology
2010 Standout
Hydrogen Sulfide Mediates Cardioprotection Through Nrf2 Signaling
2009 Standout
Prevention of Cardiac Hypertrophy by Atorvastatin in a Transgenic Rabbit Model of Human Hypertrophic Cardiomyopathy
2005
Mitochondria and Cardiovascular Aging
2012
Works of Eric Holle being referenced
An Angiotensin II Type 1 Receptor Mutant Lacking Epidermal Growth Factor Receptor Transactivation Does Not Induce Angiotensin II–Mediated Cardiac Hypertrophy
2006
Efficient genetic manipulation of the NOD-Rag1-/-IL2RgammaC-null mouse by combining in vitro fertilization and CRISPR/Cas9 technology
2014
Glycogen Synthase Kinase-3α Reduces Cardiac Growth and Pressure Overload-induced Cardiac Hypertrophy by Inhibition of Extracellular Signal-regulated Kinases
2007
Inhibition of endogenous thioredoxin in the heart increases oxidative stress and cardiac hypertrophy
2003
Efficient translocation and apoptosis induction by adenovirus encoded VP22-p53 fusion protein in human tumor cells in vitro.
2003
Inhibition of endogenous thioredoxin in the heart increases oxidative stress and cardiac hypertrophy
2003
Lats2 Is a Negative Regulator of Myocyte Size in the Heart
2008
In vitro targeted killing of human endothelial cells by co-incubation of human serum and NGR peptide conjugated human albumin protein bearing α (1-3) galactose epitopes
2004
H11 Kinase/Heat Shock Protein 22 Deletion Impairs Both Nuclear and Mitochondrial Functions of STAT3 and Accelerates the Transition Into Heart Failure on Cardiac Overload
2011
Sirt1 Regulates Aging and Resistance to Oxidative Stress in the Heart
2007
Efficient genetic manipulation of the NOD-Rag1-/-IL2RgammaC-null mouse by combining in vitro fertilization and CRISPR/Cas9 technology
2020