Citation Impact
Citing Papers
Normal gut microbiota modulates brain development and behavior
2011 Standout
Designed protein logic to target cells with precise combinations of surface antigens
2020 StandoutScienceNobel
Glycolytic Flux Signals to mTOR through Glyceraldehyde-3-Phosphate Dehydrogenase-Mediated Regulation of Rheb
2009
De novo design of allosterically switchable protein assemblies
2024 StandoutNatureNobel
Retargeting CD19 Chimeric Antigen Receptor T Cells via Engineered CD19-Fusion Proteins
2019
Engineered receptors for soluble cellular communication and disease sensing
2024 StandoutNatureNobel
A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy
2022 StandoutNobel
PCSK9: a convertase that coordinates LDL catabolism
2008
SKN-1 and Nrf2 couples proline catabolism with lipid metabolism during nutrient deprivation
2014
Cholesterol metabolism and the pathogenesis of non-alcoholic steatohepatitis
2012
Transcriptional Regulation of Human and Rat Hepatic Lipid Metabolism by the Grapefruit Flavonoid Naringenin: Role of PPARα, PPARγ and LXRα
2010
Reciprocal Regulation of Hepatic and Adipose Lipogenesis by Liver X Receptors in Obesity and Insulin Resistance
2013
Modular and tunable biological feedback control using a de novo protein switch
2019 StandoutNatureNobel
Regulation and Functions of the ER-Associated Nrf1 Transcription Factor
2022 StandoutNobel
Multi-input chemical control of protein dimerization for programming graded cellular responses
2019 StandoutNobel
The spectrum of T cell metabolism in health and disease
2017
Glucolipotoxicity: Fuel Excess and β-Cell Dysfunction
2008
Recent insights into hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD)
2008
Mitochondrial Dysfunction in C. elegans Activates Mitochondrial Relocalization and Nuclear Hormone Receptor-Dependent Detoxification Genes
2019 StandoutNobel
The Principles of Engineering Immune Cells to Treat Cancer
2017
Evolution of Inflammation in Nonalcoholic Fatty Liver Disease: The Multiple Parallel Hits Hypothesis
2010 Standout
Highly efficient CD4+ T cell targeting and genetic recombination using engineered CD4+ cell-homing mRNA-LNPs
2021 StandoutNobel
Hepatocellular carcinoma
2021 Standout
Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism
2016 Standout
Improving the safety of T-Cell therapies using an inducible caspase-9 gene
2016
Targeting the Proprotein Convertase Subtilisin/Kexin Type 9 for the Treatment of Dyslipidemia and Atherosclerosis
2013
Macrophages in atherosclerosis: a dynamic balance
2013 Standout
Type 2 diabetes as an inflammatory disease
2011 Standout
Obesity and Nonalcoholic Fatty Liver Disease: Biochemical, Metabolic, and Clinical Implications
2009 Standout
Universal Chimeric Antigen Receptors for Multiplexed and Logical Control of T Cell Responses
2018
Abnormal hepatic apolipoprotein B metabolism in type 2 diabetes
2010
Delivery technologies for cancer immunotherapy
2019 Standout
Engineered T cells: the promise and challenges of cancer immunotherapy
2016
The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD)
2016 Standout
How to improve R&D productivity: the pharmaceutical industry's grand challenge
2010 Standout
Selective stalling of human translation through small-molecule engagement of the ribosome nascent chain
2017 StandoutNobel
Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR
2012
Human antibody-based chemically induced dimerizers for cell therapeutic applications
2017
Programmable synthetic receptors: the next-generation of cell and gene therapies
2024
Differential hepatic distribution of insulin receptor substrates causes selective insulin resistance in diabetes and obesity
2016
Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial
2014 Standout
Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy
2017 Standout
Role of stearoyl-coenzyme A desaturase in regulating lipid metabolism
2008
mTOR regulation of autophagy
2010 Standout
Engineered Cell-Based Therapeutics: Synthetic Biology Meets Immunology
2019
Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice
2008
The Nrf2 regulatory network provides an interface between redox and intermediary metabolism
2014 Standout
Gut flora, Toll-like receptors and nuclear receptors: a tripartite communication that tunes innate immunity in large intestine
2008
Making CAR T Cells a Solid Option for Solid Tumors
2018
What We Talk About When We Talk About Fat
2014 Standout
Transcriptional regulation of hepatic lipogenesis
2015
SREBP and MDT-15 protectC. elegansfrom glucose-induced accelerated aging by preventing accumulation of saturated fat
2015
AKT/PKB Signaling: Navigating the Network
2017 Standout
Engineering strategies to overcome the current roadblocks in CAR T cell therapy
2019
Thalidomide as a Multi‐Template for Development of Biologically Active Compounds
2008
PCSK9 and LDL cholesterol: unravelling the target to design the bullet
2008
Strong coupling between surface plasmon polaritons and emitters: a review
2014 Standout
Thyroid hormone crosstalk with nuclear receptor signaling in metabolic regulation
2009
Defining trained immunity and its role in health and disease
2020 Standout
Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression
2019 StandoutNobel
Chimeric antigen receptor T-cell therapy — assessment and management of toxicities
2017 Standout
NF-κB, inflammation, immunity and cancer: coming of age
2018 Standout
Inflammation in obesity, diabetes, and related disorders
2022 Standout
Cadmium-induced malignant transformation of rat liver cells: Potential key role and regulatory mechanism of altered apolipoprotein E expression in enhanced invasiveness
2017
AASLD Practice Guidance on the clinical assessment and management of nonalcoholic fatty liver disease
2023 Standout
SEC24A deficiency lowers plasma cholesterol through reduced PCSK9 secretion
2013 StandoutNobel
Pathophysiology of Human Visceral Obesity: An Update
2013 Standout
A novel GTP-binding protein–adaptor protein complex responsible for export of Vangl2 from the trans Golgi network
2013 StandoutNobel
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
Pck1 Gene Silencing in the Liver Improves Glycemia Control, Insulin Sensitivity, and Dyslipidemia in db/db Mice
2008
In Vivo mRNA CAR T Cell Engineering via Targeted Ionizable Lipid Nanoparticles with Extrahepatic Tropism
2023 StandoutNobel
Transcriptional Control of Energy Homeostasis by the Estrogen-Related Receptors
2008
Nonalcoholic Fatty Liver Disease: Pathogenesis and Disease Spectrum
2016
Targeting PCSK9 for Hypercholesterolemia
2013
Molecular Mechanisms of the Anti-Obesity and Anti-Diabetic Properties of Flavonoids
2016 Standout
Killing Mechanisms of Chimeric Antigen Receptor (CAR) T Cells
2019
Chimeric antigen receptor–modified T cells: CD19 and the road beyond
2018
Pathophysiology of Type 2 Diabetes Mellitus
2020 Standout
The Effects of Cadmium Toxicity
2020 Standout
Steatosis and Steatohepatitis: Complex Disorders
2014
Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes (II)
2018 Standout
Thyroid Hormone Regulation of Metabolism
2014 Standout
RXR Partial Agonist CBt-PMN Exerts Therapeutic Effects on Type 2 Diabetes without the Side Effects of RXR Full Agonists
2012
Chimeric Antigen Receptor Therapy
2018 Standout
Creation of Customized Bioactivity within a 14-Membered Macrolide Scaffold: Design, Synthesis, and Biological Evaluation Using a Family-18 Chitinase
2015 StandoutNobel
Fluorosulfuryl Isocyanate Enabled SuFEx Ligation of Alcohols and Amines
2021 StandoutNobel
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
Survey of the 2009 commercial optical biosensor literature
2011
GTPase ARFRP1 Is Essential for Normal Hepatic Glycogen Storage and Insulin-Like Growth Factor 1 Secretion
2012
2016 ESC/EAS Guidelines for the Management of Dyslipidaemias
2016 Standout
Precise T cell recognition programs designed by transcriptionally linking multiple receptors
2020 Science
CAR T cell immunotherapy for human cancer
2018 StandoutScience
Accurate proteome-wide missense variant effect prediction with AlphaMissense
2023 StandoutScienceNobel
Synthesis of Hierarchical FeWO4 Architectures with {100}-Faceted Nanosheet Assemblies as a Robust Biomimetic Catalyst
2015
Works of Eric Hampton being referenced
Switchable CAR-T cells mediate remission in metastatic pancreatic ductal adenocarcinoma
2018
Design of Switchable Chimeric Antigen Receptor T Cells Targeting Breast Cancer
2016
The nuclear receptor LXR is a glucose sensor
2006 Nature
Time-resolved fluorescence resonance energy transfer and surface plasmon resonance-based assays for retinoid and transthyretin binding to retinol-binding protein 4
2009
Switchable control over in vivo CAR T expansion, B cell depletion, and induction of memory
2018
The self-inhibited structure of full-length PCSK9 at 1.9 Å reveals structural homology with resistin within the C-terminal domain
2007
Secreted PCSK9 promotes LDL receptor degradation independently of proteolytic activity
2007
Chemical Inhibition of ENL/AF9 YEATS Domains in Acute Leukemia
2021 StandoutNobel
Switch-mediated activation and retargeting of CAR-T cells for B-cell malignancies
2016