Citation Impact
Citing Papers
Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro
2003 StandoutNobel
The DNA-damage response in human biology and disease
2009 StandoutNature
COMPASS: A complex of proteins associated with a trithorax-related SET domain protein
2001
Tipin-Replication Protein A Interaction Mediates Chk1 Phosphorylation by ATR in Response to Genotoxic Stress
2010 StandoutNobel
Mammalian Telomeres End in a Large Duplex Loop
1999 Standout
Cellular and Gene Expression Responses Involved in the Rapid Growth Inhibition of Human Cancer Cells by RNA Interference-mediated Depletion of Telomerase RNA
2005 StandoutNobel
Evidence that Set1, a Factor Required for Methylation of Histone H3, Regulates rDNA Silencing in S. cerevisiae by a Sir2-Independent Mechanism
2002
t-loops at trypanosome telomeres
2001
RPA regulates telomerase action by providing Est1p access to chromosome ends
2003
Cell-cycle checkpoints and cancer
2004 StandoutNature
Replication Protein A phosphorylation and the cellular response to DNA damage
2004
Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain
2001 StandoutNature
Processive Utilization of the Human Telomerase Template
2004 StandoutNobel
The DNA Damage Response Kinases DNA-dependent Protein Kinase (DNA-PK) and Ataxia Telangiectasia Mutated (ATM) Are Stimulated by Bulky Adduct-containing DNA
2011 StandoutNobel
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
2005 StandoutNature
Hallmarks of aging: An expanding universe
2023 Standout
Shaping human telomeres: from shelterin and CST complexes to telomeric chromatin organization
2021 Nobel
Telomere dynamics, end-to-end fusions and telomerase activation during the human fibroblast immortalization process
1999
Telomere states and cell fates
2000 StandoutNatureNobel
A Dynamic Molecular Link between the Telomere Length Regulator TRF1 and the Chromosome End Protector TRF2
2004
Indecent Exposure
2004
A New Connection at Human Telomeres: Association of the Mre11 Complex with TRF2
2000
The Hallmarks of Cancer
2000 Standout
TIN2 Binds TRF1 and TRF2 Simultaneously and Stabilizes the TRF2 Complex on Telomeres
2004
TRF2 Protects Human Telomeres from End-to-End Fusions
1998
Gene Ontology: tool for the unification of biology
2000 Standout
Progressive cis-inhibition of telomerase upon telomere elongation
1999
TRF1 is degraded by ubiquitin-mediated proteolysis after release from telomeres
2003
Comparison between TRF2 and TRF1 of their telomeric DNA‐bound structures and DNA‐binding activities
2004
Natural and pharmacological regulation of telomerase
2002
NFBD1, a Novel Nuclear Protein with Signature Motifs of FHA and BRCT, and an Internal 41-Amino Acid Repeat Sequence, Is an Early Participant in DNA Damage Response
2003
Telomerase and the maintenance of chromosome ends
1999 Nobel
A DNA damage checkpoint response in telomere-initiated senescence
2003 StandoutNature
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
Telomeres and telomerase: the path from maize, Tetrahymena and yeast to human cancer and aging
2006 StandoutNobel
Short Telomeres, even in the Presence of Telomerase, Limit Tissue Renewal Capacity
2005 StandoutNobel
Telomeres Do D-Loop–T-Loop
1999 StandoutNobel
Blinded by the Light: The Growing Complexity of p53
2009 Standout
The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4
2001
Expression of mutant telomerase in immortal telomerase-negative human cells results in cell cycle deregulation, nuclear and chromosomal abnormalities and rapid loss of viability
2001
Protection of mammalian telomeres
2002
Telomere dysfunction and tumour suppression: the senescence connection
2008
Cdk1-Dependent Phosphorylation of Cdc13 Coordinates Telomere Elongation during Cell-Cycle Progression
2009 StandoutNobel
ERCC1/XPF Removes the 3′ Overhang from Uncapped Telomeres and Represses Formation of Telomeric DNA-Containing Double Minute Chromosomes
2003
TRF1 binds a bipartite telomeric site with extreme spatial flexibility
1999
Alternative lengthening of telomeres: models, mechanisms and implications
2010
Identification of Human Rap1
2000
p53 Deficiency Rescues the Adverse Effects of Telomere Loss and Cooperates with Telomere Dysfunction to Accelerate Carcinogenesis
1999 StandoutNobel
Switching and Signaling at the Telomere
2001 StandoutNobel
Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres
2000
Comparing effects of mTR and mTERT deletion on gene expression and DNA damage response: a critical examination of telomere length maintenance-independent roles of telomerase
2009 StandoutNobel
Defective meiosis in telomere-silencing mutants of Schizosaccharomyces pombe
1998 Nature
The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome Stability
2001 StandoutNobel
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
2005 StandoutNature
The Hallmarks of Aging
2013 Standout
Phosphorylation of H2AX at Short Telomeres in T Cells and Fibroblasts
2004 StandoutNobel
Shelterin: the protein complex that shapes and safeguards human telomeres
2005 Standout
Active genes are tri-methylated at K4 of histone H3
2002 StandoutNature
Tankyrase promotes telomere elongation in human cells
2000
DNA damage response at functional and dysfunctional telomeres
2008
Evidence of a differential organization of chromatin containing terminal or interstitial (TTAGGG)<sub>n</sub> repeats by in situ digestion with nucleases
1998
A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping
2014 Standout
The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator
2012 StandoutNobel
DNA Damage Foci at Dysfunctional Telomeres
2003
AID is required to initiate Nbs1/γ-H2AX focus formation and mutations at sites of class switching
2001 StandoutNatureNobel
The telomerase reverse transcriptase: components and regulation
1998
The cancer genome
2009 StandoutNature
Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes
2013 Standout
The human telomere‐associated protein TIN2 stimulates interactions between telomeric DNA tracts in vitro
2003
A trithorax-group complex purified from Saccharomyces cerevisiae is required for methylation of histone H3
2001 StandoutNobel
Telomerase core components protect Candida telomeres from aberrant overhang accumulation
2007 StandoutNobel
A molecular switch underlies a human telomerase disease
2002 StandoutNobel
Reconstitution of a human ATR-mediated checkpoint response to damaged DNA
2007 StandoutNobel
Stochasticity in gene expression: from theories to phenotypes
2005 Standout
Telomere length is paternally inherited and is associated with parental lifespan
2007 StandoutNobel
Ku is associated with the telomere in mammals
1999 StandoutNobel
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Functional Interaction between Poly(ADP-Ribose) Polymerase 2 (PARP-2) and TRF2: PARP Activity Negatively Regulates TRF2
2004
Telomeres: Cancer to Human Aging
2006
A Trypanosoma brucei Protein Complex That Binds G-overhangs and Co-purifies with Telomerase Activity
2002 StandoutNobel
CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2
2006
TIN2 Mediates Functions of TRF2 at Human Telomeres
2004
Telomere fusions caused by mutating the terminal region of telomeric DNA
2000 StandoutNobel
Control of Human Telomere Length by TRF1 and TRF2
2000
SIRT6, a Mammalian Deacylase with Multitasking Abilities
2019
Cancer Genome Landscapes
2013 StandoutScience
How the human telomeric proteins TRF1 and TRF2 recognize telomeric DNA: a view from high‐resolution crystal structures
2004
Telomerase in kinetoplastid parasitic protozoa
1999 StandoutNobel
T-loop assembly in vitro involves binding of TRF2 near the 3' telomeric overhang
2001
A low threshold level of expression of mutant-template telomerase RNA inhibits human tumor cell proliferation
2001 StandoutNobel
Toward Maintaining the Genome: DNA Damage and Replication Checkpoints
2002
Transcriptional Regulatory Elements in the Human Genome
2006
How Shelterin Protects Mammalian Telomeres
2008 Standout
Template Boundary in a Yeast Telomerase Specified by RNA Structure
2000 StandoutScienceNobel
Positive and negative regulation of telomerase access to the telomere
2000
Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints
2004 StandoutNobel
Myb-Related Schizosaccharomyces pombecdc5p Is Structurally and Functionally Conserved in Eukaryotes
1998
Works of Éric Gilson being referenced
Topoisomerase IIIα is required for normal proliferation and telomere stability in alternative lengthening of telomeres
2008
SIRT6 interacts with TRF2 and promotes its degradation in response to DNA damage
2016
The set1Δ mutation unveils a novel signaling pathway relayed by the Rad53-dependent hyperphosphorylation of replication protein A that leads to transcriptional activation of repair genes
2001
Telomeric localization of TRF2, a novel human telobox protein
1997
Telomere damage induced by the G-quadruplex ligand RHPS4 has an antitumor effect
2007
Insulator dynamics and the setting of chromatin domains
2004