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Citing Papers
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2001
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2004
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2001
RAP1: a protean regulator in yeast
1994
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1998 StandoutNatureNobel
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2006
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1994 StandoutNobel
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Model for signal sequence recognition from amino-acid sequence of 54K subunit of signal recognition particle
1989 StandoutNatureNobel
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1995
A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides
1988 StandoutNatureNobel
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2002
Identification of genes that are associated with DNA repeats in prokaryotes
2002
Rap1P and Telomere Length Regulation in Yeast
2007
Structural model of ATP-binding proteing associated with cystic fibrosis, multidrug resistance and bacterial transport
1990 Nature
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2006
Telomerase-Mediated Telomere Addition In Vivo Requires DNA Primase and DNA Polymerases α and δ
1999
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2000 StandoutNatureNobel
We gather together: insulators and genome organization
2007
Genetic identification of exported proteins in Streptococcus pneumoniae
1993
From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair
1997
CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III
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Structure of the recA protein–ADP complex
1992 StandoutNatureNobel
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2001 StandoutNobel
Functionally interacting telomerase RNAs in the yeast telomerase complex
1997 StandoutNobel
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2002
Progressive cis-inhibition of telomerase upon telomere elongation
1999
Late S Phase-Specific Recruitment of Mre11 Complex Triggers Hierarchical Assembly of Telomere Replication Proteins in Saccharomyces cerevisiae
2005
TIN2, a new regulator of telomere length in human cells
1999
Telomere Length and Telomerase Expression in Atypical Adenomatous Hyperplasia and Small Bronchioloalveolar Carcinoma of the Lung
2007
Telomerase and ATM/Tel1p Protect Telomeres from Nonhomologous End Joining
2003 StandoutNobel
Genetics and Epigenetics of the Multifunctional Protein CTCF
2007
DNA Degradation at Unprotected Telomeres in Yeast Is Regulated by the CDK1 (Cdc28/Clb) Cell-Cycle Kinase
2006
Distinct roles for yeast Stn1 in telomere capping and telomerase inhibition
2008
Runaway telomere elongation caused by telomerase RNA gene mutations
1995 StandoutNatureNobel
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1997
POT1 as a terminal transducer of TRF1 telomere length control
2003 Nature
Protein-DNA interactions in soluble telosomes fromSaccharomyces cerevisiae
1995
Control of telomere growth by interactions of RAP1 with the most distal telomeric repeats
1996 StandoutNatureNobel
Nuclear pore complexes in the organization of silent telomeric chromatin
2000 Nature
Cdk1-Dependent Phosphorylation of Cdc13 Coordinates Telomere Elongation during Cell-Cycle Progression
2009 StandoutNobel
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2012 StandoutNatureNobel
Telomere Length Homeostasis Is Achieved via a Switch between Telomerase- Extendible and -Nonextendible States
2004
Telomerase and Tel1p Preferentially Associate with Short Telomeres in S. cerevisiae
2007
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2000
Switching and Signaling at the Telomere
2001 StandoutNobel
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1999 StandoutNatureNobel
Nucleolar protein PinX1p regulates telomerase by sequestering its protein catalytic subunit in an inactive complex lacking telomerase RNA
2004 StandoutNobel
Nature of DNA polymorphism in the direct repeat cluster of Mycobacterium tuberculosis; application for strain differentiation by a novel typing method
1993
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2003
Reciprocal Association of the Budding Yeast ATM-Related Proteins Tel1 and Mec1 with Telomeres In Vivo
2004
TRF1 is a dimer and bends telomeric DNA
1997
DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis
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Fission yeast Taz1 protein is required for meiotic telomere clustering and recombination
1998 StandoutNatureNobel
Chromosome ends: all the same under their caps
1997
Isolation and characterization of twoSaccharomyces cerevisiaegenes that encode proteins that bind to (TG1–3)nsingle strand telomeric DNAin vitro
1994
Telomerase-Independent Lengthening of Yeast Telomeres Occurs by an Abrupt Rad50p-Dependent, Rif-Inhibited Recombinational Process
2000
Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing
1998
Telomeres and human disease: ageing, cancer and beyond
2005
TRF1 promotes parallel pairing of telomeric tracts in vitro
1998
MRT-2 checkpoint protein is required for germline immortality and telomere replication in C. elegans
2000 Nature
Pol12, the B subunit of DNA polymerase α, functions in both telomere capping and length regulation
2004
Telomerase: biochemical considerations for enzyme and substrate
2002
Penicillin tolerance genes ofStreptococcus pneumoniae: the ABC‐type manganese permease complex Psa
1998 StandoutNobel
Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy
1993 StandoutNatureNobel
Telomerase RNA Template Mutations Reveal Sequence-Specific Requirements for the Activation and Repression of Telomerase Action at Telomeres
2000 StandoutNobel
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2009 Standout
The Telobox, a Myb-Related Telomeric DNA Binding Motif Found in Proteins from Yeast, Plants and Human
1996
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
1997 Standout
Control of telomere length by the human telomeric protein TRF1
1997 Nature
Meiotic nuclear reorganization: switching the position of centromeres and telomeres in the fission yeast Schizosaccharomyces pombe
1997
Primary structure and genomic organization of the histidine-rich protein of the malaria parasite Plasmodium lophurae
1984 StandoutNatureNobel
An Animal Model for Cystic Fibrosis Made by Gene Targeting
1992 StandoutScienceNobel
A novel mechanism for telomere size control in Saccharomyces cerevisiae.
1996
Role of the Nuclear Transport Factor p10 in Nuclear Import
1996 StandoutScienceNobel
The clustering of telomeres and colocalization with Rap1, Sir3, and Sir4 proteins in wild-type Saccharomyces cerevisiae.
1996
Molecular Recognition of Protein Surfaces: High Affinity Ligands for the CBP KIX Domain
2003
Rap1 protein regulates telomere turnover in yeast
1998 StandoutNobel
Computation-Guided Backbone Grafting of a Discontinuous Motif onto a Protein Scaffold
2011 StandoutScienceNobel
Functional Multimerization of the Human Telomerase Reverse Transcriptase
2001
TELOMERES AND THEIR CONTROL
2000 StandoutNobel
A class of single-stranded telomeric DNA-binding proteins required for Rap1p localization in yeast nuclei.
1995
Mammalian multidrug resistance gene: Complete cDNA sequence indicates strong homology to bacterial transport proteins
1986
Quality Control by DNA Repair
1999 StandoutScienceNobel
Telomere Folding Is Required for the Stable Maintenance of Telomere Position Effects in Yeast
2000
Sir Proteins, Rif Proteins, and Cdc13p Bind Saccharomyces Telomeres In Vivo
1998
A new cell division operon inEscherichia coli
1986
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
Domainal evolution of a prokaryotic DNA repair protein and its relationship to active-transport proteins
1986 StandoutNatureNobel
A novel Rap1p-interacting factor, Rif2p, cooperates with Rif1p to regulate telomere length in Saccharomyces cerevisiae.
1997
Homology between P-glycoprotein and a bacterial haemolysin transport protein suggests a model for multidrug resistance
1986 Nature
Nucleotide binding by membrane components of bacterial periplasmic binding protein-dependent transport systems.
1985
SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast.
1997
A family of related ATP-binding subunits coupled to many distinct biological processes in bacteria
1986 Nature
The nodI gene product of Rhizobium leguminosarum is closely related to ATP-binding bacterial transport proteins; nucleotide sequence analysis of the nodI and nodJ genes
1986
Sequences of theE. coli uvrCgene and protein
1984 StandoutNobel
Telomerase Catalytic Subunit Homologs from Fission Yeast and Human
1997 StandoutScienceNobel
Unusual nucleotide arrangement with repeated sequences in the Escherichia coli K-12 chromosome
1989
A Chlamydomonas protein that binds single-stranded G-strand telomere DNA.
1994
Control of Human Telomere Length by TRF1 and TRF2
2000
Dependence of the Regulation of Telomere Length on the Type of Subtelomeric Repeat in the Yeast Saccharomyces cerevisiae
1999
Telomerase in Yeast
1995 StandoutScienceNobel
Telomere-associated chromosome breakage in fission yeast results in variegated expression of adjacent genes.
1994
Telomeric Protein Distributions and Remodeling Through the Cell Cycle inSaccharomyces cerevisiae
2003 StandoutNobel
Isolation and characterization of nuclear envelopes from the yeast Saccharomyces.
1995 StandoutNobel
The nucleotide sequences of the rbsD, rbsA, and rbsC genes of Escherichia coli K12.
1986
Telomeres and telomerase
2004 StandoutNobel
Counting of Rif1p and Rif2p on Saccharomyces cerevisiae Telomeres Regulates Telomere Length
2004 StandoutNobel
Dynamics of Telomeric DNA Turnover in Yeast
2002 StandoutNobel
DNA end-joining: from yeast to man
1998
Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA
1989 StandoutScience
Silent information regulator protein complexes in Saccharomyces cerevisiae : A SIR2/SIR4 complex and evidence for a regulatory domain in SIR4 that inhibits its interaction with SIR3
1997
Atomic structures and function of periplasmic receptors for active transport and chemotaxis
1991
Accelerated Aging and Nucleolar Fragmentation in Yeast sgs1 Mutants
1997 Science
Clathrin: A Role in the Intracellular Retention of a Golgi Membrane Protein
1989 StandoutScienceNobel
An unusual sequence arrangement in the telomeres of the germ-line micronucleus in Tetrahymena thermophila.
1995 StandoutNobel
The Yeast Telomere Length Counting Machinery Is Sensitive to Sequences at the Telomere-Nontelomere Junction
1999
Dynamics of chromosome organization and pairing during meiotic prophase in fission yeast.
1994
Nucleotide sequence of the btuCED genes involved in vitamin B12 transport in Escherichia coli and homology with components of periplasmic-binding-protein-dependent transport systems
1986
Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells
1986 Standout
The organization, mechanism of action, and evolution of periplasmic transport systems
1983
Crystallographic evidence of a large ligand-induced hinge-twist motion between the two domains of the maltodextrin binding protein involved in active transport and chemotaxis
1992
ATP-binding sites in the membrane components of histidine permease, a periplasmic transport system.
1984
Telomeres: Beginning to Understand the End
1995 Science
STRUCTURE, FUNCTION, AND REPLICATION OF SACCHAROMYCES CEREVISIAE TELOMERES
1996
CTCF Interacts with and Recruits the Largest Subunit of RNA Polymerase II to CTCF Target Sites Genome-Wide
2007
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
A Sense of the End
2000 Science
The carboxy termini of Sir4 and Rap1 affect Sir3 localization: evidence for a multicomponent complex required for yeast telomeric silencing.
1995
Positive and negative regulation of telomerase access to the telomere
2000
Block in Anaphase Chromosome Separation Caused by a Telomerase Template Mutation
1997 StandoutScienceNobel
Glycosylation and processing of prepro-α-factor through the yeast secretory pathway
1984 StandoutNobel
Rewriting a genome
2013 StandoutNatureNobel
Action of a RAP1 carboxy-terminal silencing domain reveals an underlying competition between HMR and telomeres in yeast.
1995
The Est1 Subunit of Saccharomyces cerevisiae Telomerase Makes Multiple Contributions to Telomere Length Maintenance
2002
Evidence that a complex of SIR proteins interacts with the silencer and telomere-binding protein RAP1.
1994
Est1 and Cdc13 as Comediators of Telomerase Access
1999 Science
Internal tracts of telomeric DNA act as silencers in Saccharomyces cerevisiae.
1994
Fission Yeast Dna2 Is Required for Generation of the Telomeric Single-Strand Overhang
2004
Extension of Life-Span by Introduction of Telomerase into Normal Human Cells
1998 StandoutScience
Works of Éric Gilson being referenced
SIR3 and SIR4 proteins are required for the positioning and integrity of yeast telomeres
1993
Cohabitation of insulators and silencing elements in yeast subtelomeric regions
1999
RPA regulates telomerase action by providing Est1p access to chromosome ends
2003
Role of the telomeric DNA-binding protein TRF2 in the stability of human chromosome ends
1998
The Positioning of Yeast Telomeres Depends on SIR3, SIR4, and the Integrity of the Nuclear Membrane
1993
Nuclear architecture and spatial positioning help establish transcriptional states of telomeres in yeast
2002
Bacterial Interspersed Mosaic Elements (BIMEs) Are a Major Source of Sequence Polymorphism in Escherichia coli Intergenic Regions Including Specific Associations With a New Insertion Sequence
1997
Subtelomeric proteins negatively regulate telomere elongation in budding yeast
2006
Chromatin: A sticky silence
1996
DNA polymerase I and a protein complex bind specifically toE.colipalindromic unit highly repetitive DNA: implications for bacterial chromosome organization
1990
Cell cycle restriction of telomere elongation
2000
The Human Enhancer Blocker CTC-binding Factor Interacts with the Transcription Factor Kaiso
2005
RPA facilitates telomerase activity at chromosome ends in budding and fission yeasts
2012
Imaging the Asymmetrical DNA Bend Induced by Repressor Activator Protein 1 with Scanning Tunneling Microscopy
1994
Multipurpose role for RAP1, a yeast DNA looping protein
1989
TRF2/RAP1 and DNA–PK mediate a double protection against joining at telomeric ends
2010
Distortion of the DNA Double Helix by RAP1 at Silencers and Multiple Telomeric Binding Sites
1993
A family of dispersed repetitive extragenic palindromic DNA sequences in E. coli.
1984
Targeting Assay To Study the cis Functions of Human Telomeric Proteins: Evidence for Inhibition of Telomerase by TRF1 and for Activation of Telomere Degradation by TRF2
2002
Sequence of themalKgene inE.coliK12
1982
Silencing of genes at nontelomeric sites in yeast is controlled by sequestration of silencing factors at telomeres by Rap 1 protein.
1996
Extensive homology between membrane-associated components of histidine and maltose transport systems of Salmonella typhimurium and Escherichia coli.
1982
Human telomeric position effect is determined by chromosomal context and telomeric chromatin integrity
2002
Expression of mRNAs for telomeric repeat binding factor (TRF)-1 and TRF2 in atypical adenomatous hyperplasia and adenocarcinoma of the lung.
2003
Palindromic units: a case of highly repetitive DNA sequences in bacteria
1987
Functional Interaction between Poly(ADP-Ribose) Polymerase 2 (PARP-2) and TRF2: PARP Activity Negatively Regulates TRF2
2004
A Protein-Counting Mechanism for Telomere Length Regulation in Yeast
1997 Science
Evidence for high affinity binding-protein dependent transport systems in gram-positive bacteria and in Mycoplasma.
1988
Evidence for silencing compartments within the yeast nucleus: a role for telomere proximity and Sir protein concentration in silencer-mediated repression.
1996