Citation Impact
Citing Papers
Structures of the CRISPR genome integration complex
2017 StandoutScienceNobel
Novel therapeutic strategies targeting HIV integrase
2012
Host hindrance to HIV-1 replication in monocytes and macrophages
2010
Processing of Viral DNA Ends Channels the HIV-1 Integration Reaction to Concerted Integration*[boxs]
2005
Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors
2009
Evolutionary History of a Specialized P450 Propane Monooxygenase
2008 StandoutNobel
Structure of the RAG1 nonamer binding domain with DNA reveals a dimer that mediates DNA synapsis
2009 StandoutNobel
Allosteric phenomena in cytochrome P450‐catalyzed monooxygenations
2001
Yeast RNA polymerase III transcription factors and effectors
2012
Nuclear landscape of HIV-1 infection and integration
2016
Acute kidney injury
2012 Standout
Enantioselective, intermolecular benzylic C–H amination catalysed by an engineered iron-haem enzyme
2017 StandoutNobel
QM/MM Methods for Biomolecular Systems
2009 Standout
Cytochrome P450
1995
Allosteric Inhibitor Development Targeting HIV‐1 Integrase
2011
Highly sensitive naked-eye and fluorescence “turn-on” detection of Cu2+ using Fenton reaction assisted signal amplification
2010
RAG1-DNA Binding in V(D)J Recombination
2003
The Functional Interaction of the Hepatitis C Virus Helicase Molecules Is Responsible for Unwinding Processivity
2004
Discovery of a regioselectivity switch in nitrating P450s guided by molecular dynamics simulations and Markov models
2016 StandoutNobel
Structural determinants of cytochrome P450 substrate specificity, binding affinity and catalytic rate
1998
HIV-1 Integrase Inhibitor Resistance and Its Clinical Implications
2011
Periluminal Distribution of HIV-Binding Target Cells and Gp340 in the Oral, Cervical and Sigmoid/Rectal Mucosae: A Mapping Study
2015 StandoutNobel
CRISPR Immunological Memory Requires a Host Factor for Specificity
2016 StandoutNobel
Acute Renal Failure in Critically Ill Patients<SUBTITLE>A Multinational, Multicenter Study</SUBTITLE>
2005 Standout
Contribution of Opening and Bending Dynamics to Specific Recognition of DNA Damage
2003
Mechanisms of Helicases
2006
Far-red to near infrared analyte-responsive fluorescent probes based on organic fluorophore platforms for fluorescence imaging
2012 Standout
The Binding Sites on Human Heme Oxygenase-1 for Cytochrome P450 Reductase and Biliverdin Reductase
2003
Foreign DNA capture during CRISPR–Cas adaptive immunity
2015 StandoutNatureNobel
A Functional Mini-Integrase in a Two-Protein Type V-C CRISPR System
2019 StandoutNobel
Crystal structure of cytochrome P‐450cam complexed with the (1S)‐camphor enantiomer
1997
Recruitment of RNA polymerase III to its target promoters
2002
Newly approved integrase inhibitors for clinical treatment of AIDS
2014
Conformational States of Cytochrome P450cam Revealed by Trapping of Synthetic Molecular Wires
2004
Screening of the Pan-African Natural Product Library Identifies Ixoratannin A-2 and Boldine as Novel HIV-1 Inhibitors
2015 StandoutNobel
Heme Oxygenase-1/Carbon Monoxide: From Basic Science to Therapeutic Applications
2006 Standout
Integrase inhibitors to treat HIV/Aids
2005
A novel human AP endonuclease with conserved zinc‐finger‐like motifs involved in DNA strand break responses
2007
Acute kidney injury
2019 Standout
The DNA Damage Response: Making It Safe to Play with Knives
2010 Standout
To translate, or not to translate: viral and host mRNA regulation by interferon-stimulated genes
2015 StandoutNobel
Structure, dynamics, and function of the monooxygenase P450 BM-3: insights from computer simulations studies
2015
Mechanisms that regulate production of reactive oxygen species by cytochrome P450
2004
Effects of different doses in continuous veno-venous haemofiltration on outcomes of acute renal failure: a prospective randomised trial
2000 Standout
New first and second generation inhibitors of human immunodeficiency virus-1 integrase
2011
Detours and shortcuts to transcription reinitiation
2003
Real-Time Kinetics of Gene Activity in Individual Bacteria
2005 Standout
Conformational heterogeneity of cytochrome P450 3A4 revealed by high pressure spectroscopy
2003
Membrane Binding and Substrate Access Merge in Cytochrome P450 7A1, a Key Enzyme in Degradation of Cholesterol
2001
How do substrates enter and products exit the buried active site of cytochrome P450cam? 2. Steered molecular dynamics and adiabatic mapping of substrate pathways 1 1Edited by J. Thornton
2000
SERS nanoprobes for the monitoring of endogenous nitric oxide in living cells
2016
Biology and Applications of CRISPR Systems: Harnessing Nature’s Toolbox for Genome Engineering
2016 StandoutNobel
Integrase-mediated spacer acquisition during CRISPR–Cas adaptive immunity
2015 StandoutNatureNobel
A Quantum Mechanics/Molecular Mechanics Study of the Protein–Ligand Interaction for Inhibitors of HIV‐1 Integrase
2007
SF1 and SF2 helicases: family matters
2010
New Approach for Local Structure Analysis of the Tyrosine Domain in Proteins by Using a Site‐Specific and Polarity‐Sensitive Fluorescent Probe
2009
Calculation of binding energy using BLYP/MM for the HIV-1 integrase complexed with the S-1360 and two analogues
2007
Effect of Conformational Dynamics on Substrate Recognition and Specificity as Probed by the Introduction of a de Novo Disulfide Bond into Cytochrome P450 2B1
2009
Identification of microRNAs of the herpesvirus family
2005 StandoutNobel
Engineered Alkane‐Hydroxylating Cytochrome P450BM3 Exhibiting Nativelike Catalytic Properties
2007 StandoutNobel
Structure, Dynamics, Assembly, and Evolution of Protein Complexes
2014
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Requirement for Integrase during Reverse Transcription of Human Immunodeficiency Virus Type 1 and the Effect of Cysteine Mutations of Integrase on Its Interactions with Reverse Transcriptase
2004
A Tunable Photosensor
2008 StandoutNobel
Hydration energy landscape of the active site cavity in cytochrome P450cam.
1998
Quantifying the Dynamics of Protein Self-Organization Using Deep Learning Analysis of Atomic Force Microscopy Data
2020 StandoutNobel
The Enzymes, Regulation, and Genetics of Bile Acid Synthesis
2003 Standout
Prespacer processing and specific integration in a Type I-A CRISPR system
2017
Genomes in Focus: Development and Applications of CRISPR‐Cas9 Imaging Technologies
2017 StandoutNobel
SWISS-MODEL: homology modelling of protein structures and complexes
2018 Standout
CAN-catalyzed three-component reaction between anilines and alkyl vinyl ethers: stereoselective synthesis of 2-methyl-1,2,3,4-tetrahydroquinolines and studies on their aromatization
2006
Surface-Enhanced Raman Spectroscopy for Bioanalysis: Reliability and Challenges
2018 Standout
Chemical Modification of Coumarin Dimer and HIV-1 Integrase Inhibitory Activity.
2002
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Structural Aspects of Ligand Binding to and Electron Transfer in Bacterial and Fungal P450s
2004
Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems
2013 Standout
CRISPR-Cas: biology, mechanisms and relevance
2016 StandoutNobel
Theoretical Study on Compound I Formation in Monooxygenation Mechanism by Cytochrome P450
2004
Advances in the Chemistry of Tetrahydroquinolines
2011 Standout
Visual detection of copper(ii) based on the aggregation of gold nano-particles via click chemistry
2012
The Caenorhabditis elegans ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways
2022 StandoutNobel
Computational Alchemy To Calculate Absolute Protein−Ligand Binding Free Energy
1998
Studying Hepatitis C Virus: Making the Best of a Bad Virus
2007 StandoutNobel
Hydration energy landscape of the active site cavity in cytochrome P450cam
1998
GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkit
2013 Standout
The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway
2010 Standout
Engineering Biomolecular Self‐Assembly at Solid–Liquid Interfaces
2020 StandoutNobel
STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets
2018 Standout
Fluorescent Chemosensors Based on Spiroring-Opening of Xanthenes and Related Derivatives
2011 Standout
Intrinsic sequence specificity of the Cas1 integrase directs new spacer acquisition
2015
pH-Operated Nanopistons on the Surfaces of Mesoporous Silica Nanoparticles
2010 StandoutNobel
The Engagement of Activating FcγRs Inhibits Primate Lentivirus Replication in Human Macrophages
2006 StandoutNobel
Dumbbells, Trikes and Quads: Organic–Inorganic Hybrid Nanoarchitectures Based on “Clicked” Gold Nanoparticles
2013 StandoutNobel
Heme-Containing Oxygenases
1996 Standout
Disentangling Rotational Dynamics and Ordering Transitions in a System of Self-Organizing Protein Nanorods via Rotationally Invariant Latent Representations
2021 StandoutNobel
Mechanism of Oxidation Reactions Catalyzed by Cytochrome P450 Enzymes
2004 Standout
Convenient, two-step synthesis of 2-styrylquinolines: an application of the CAN-catalyzed vinylogous type-II Povarov reaction
2009
Simulating the Effect of DNA Polymerase Mutations on Transition-State Energetics and Fidelity: Evaluating Amino Acid Group Contribution and Allosteric Coupling for Ionized Residues in Human Pol β
2006 StandoutNobel
Structure and Chemistry of Cytochrome P450
2005 Standout
Works of Eric Deprez being referenced
Uncoupling of the base excision and nucleotide incision repair pathways reveals their respective biological roles
2006
Values of Neutral Endopeptidase 24.11 As a Tubular Marker in Human Renal Interstitial Fibrosis With Tubular Atrophy
1994
Specific and non-specific effects of potassium cations on substrate–protein interactions in cytochromes P450cam and P450lin
2002
Mechanism of HIV-1 Integrase Inhibition by Styrylquinoline Derivatives in Vitro
2004
Conformational dynamics of cytochrome P-450cam as monitored by photoacoustic calorimetry
1993
Efficient and Specific Internal Cleavage of a Retroviral Palindromic DNA Sequence by Tetrameric HIV-1 Integrase
2007
High-pressure-induced transitions in microsomal cytochrome P450 2B4 in solution: Evidence for conformational inhomogeneity in the oligomers
1995
The Escherichia coli RecQ Helicase Functions as a Monomer
2003
Impairment of Human Immunodeficiency Virus Type-1 Integrase SUMOylation Correlates with an Early Replication Defect
2011
Antagonistic effects of hydrostatic pressure and osmotic pressure on cytochrome P-450cam spin transition
1995
Electrostatic Control of the Substrate Access Channel in Cytochrome P-450cam
1994
The G140S mutation in HIV integrases from raltegravir-resistant patients rescues catalytic defect due to the resistance Q148H mutation
2008
Integrase and integration: biochemical activities of HIV-1 integrase
2008
A cooperative and specific DNA-binding mode of HIV-1 integrase depends on the nature of the metallic cofactor and involves the zinc-containing N-terminal domain
2010
Multiple Escherichia coli RecQ Helicase Monomers Cooperate to Unwind Long DNA Substrates
2010
Relationship between the Oligomeric Status of HIV-1 Integrase on DNA and Enzymatic Activity
2006
HIV-1 Integrase Catalytic Core: Molecular Dynamics and Simulated Fluorescence Decays
2001
Impact of Y143 HIV-1 Integrase Mutations on Resistance to Raltegravir In Vitro and In Vivo
2009
Rational design of a fluorescent NADPH derivative imaging constitutive nitric-oxide synthases upon two-photon excitation
2012
Disulfide-Linked Integrase Oligomers Involving C280 Residues Are Formed In Vitro and In Vivo but Are Not Essential for Human Immunodeficiency Virus Replication
2002
Improved Binding of Cytochrome P450cam Substrate Analogues Designed To Fill Extra Space in the Substrate Binding Pocket
1996
DNA binding induces dissociation of the multimeric form of HIV-1 integrase: A time-resolved fluorescence anisotropy study
2001
Styrylquinolines, Integrase Inhibitors Acting Prior to Integration: a New Mechanism of Action for Anti-Integrase Agents
2004
Role of the Polarity of the Heme Environment for the CO Stretch Modes in Cytochrome P-450cam-CO
1996
Oligomeric States of the HIV-1 Integrase As Measured by Time-Resolved Fluorescence Anisotropy
2000
A Subunit of Yeast TFIIIC Participates in the Recruitment of TATA-Binding Protein
1999
Determinants of Mg2+-Dependent Activities of Recombinant Human Immunodeficiency Virus Type 1 Integrase
2000
Origin of the Photoacoustic Signal in Cytochrome P-450cam: Role of the Arg186−Asp251−Lys178 Bifurcated Salt Bridge
1997
Click Chemistry to Fluorescent Amino Esters: Synthesis and Spectroscopic Studies
2010