Citation Impact
Citing Papers
Identification of Ubiquitin Ligases Required for Skeletal Muscle Atrophy
2001 StandoutScience
Cellular Source and Amount of Vascular Endothelial Growth Factor and Platelet-Derived Growth Factor in Tumors Determine Response to Angiogenesis Inhibitors
2009
Activation of Drosophila Toll During Fungal Infection by a Blood Serine Protease
2002 StandoutScienceNobel
Directed evolution of cytochrome c for carbon–silicon bond formation: Bringing silicon to life
2016 StandoutScienceNobel
Targeted cell killing by reconstituted caspases
2007 StandoutNobel
PIEZO ion channel is required for root mechanotransduction in Arabidopsis thaliana
2021 StandoutNobel
Production of amorphadiene in yeast, and its conversion to dihydroartemisinic acid, precursor to the antimalarial agent artemisinin
2012 Standout
Impact of protein-protein contacts on the conformation of thrombin-bound hirudin studied by comparison with the nuclear magnetic resonance solution structure of hirudin(1–51)
1992 StandoutNobel
Invertebrate biology: New medical and scientific uses of the leech
1986 Nature
Structural Basis of Transcription
2004 StandoutNobel
Laboratory evolution of peroxide-mediated cytochrome P450 hydroxylation
1999 StandoutNatureNobel
Expression of Gastrointestinal Glutathione Peroxidase Is Inversely Correlated to the Presence of Hepatitis C Virus Subgenomic RNA in Human Liver Cells
2004
Small-Molecule Inhibition of c-MYC:MAX Leucine Zipper Formation Is Revealed by Ion Mobility Mass Spectrometry
2012 StandoutNobel
Domains specifying thrombin–receptor interaction
1991 Nature
High-resolution crystal structure of human protease-activated receptor 1
2012 StandoutNatureNobel
Crystal Structure of Thermus aquaticus Core RNA Polymerase at 3.3 Å Resolution
1999
.alpha.1-Proteinase Inhibitor Variant T345R. Influence of P14 Residue on Substrate and Inhibitory Pathways
1994
The structural puzzle of how serpin serine proteinase inhibitors work
1996
A Panel of Cytochrome P450 BM3 Variants to Produce Drug Metabolites and Diversify Lead Compounds
2009 StandoutNobel
A new logic for DNA engineering using recombination in Escherichia coli
1998
Recombinant adenovirus as a methodology for exploration of physiologic functions of growth factor pathways
2007
Prospects for a vaccine against the hepatitis C virus
2005 StandoutNatureNobel
Genetically programmed chiral organoborane synthesis
2017 StandoutNatureNobel
The coming of age of de novo protein design
2016 StandoutNatureNobel
A Serpin Shapes the Extracellular Environment to Prevent Influenza A Virus Maturation
2015 StandoutNobel
Transmembrane Topologies of Ca2+-permeable Mechanosensitive Channels MCA1 and MCA2 in Arabidopsis thaliana
2015
Nuclear magnetic resonance solution structure of hirudin(1–51) and comparison with corresponding three-dimensional structures determined using the complete 65-residue hirudin polypeptide chain
1992 StandoutNobel
Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
1995 Standout
Enzymatic functionalization of carbon–hydrogen bonds
2010 StandoutNobel
The conformations of hirudin in solution: a study using nuclear magnetic resonance, distance geometry and restrained molecular dynamics
1987
Comparative immunogenicity analysis of modified vaccinia Ankara vectors expressing native or modified forms of hepatitis C virus E1 and E2 glycoproteins
2004
Refined structure of the Hirudin-thrombin complex
1991 Nobel
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
Use of fragments of hirudin to investigate thrombin‐hirudin interaction
1990
Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase
2005 StandoutNatureNobel
What makes a P450 tick?
2013
Primary structures of new ‘iso‐hirudins’
1989
The Structural Mechanism of Translocation and Helicase Activity in T7 RNA Polymerase
2004 StandoutNobel
Wnt signalling in stem cells and cancer
2005 StandoutNature
Molecular mechanisms and clinical applications of angiogenesis
2011 StandoutNature
Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
2009 StandoutNature
Selection of single-stranded DNA molecules that bind and inhibit human thrombin
1992 StandoutNature
TMEM41B Is a Pan-flavivirus Host Factor
2020 StandoutNobel
The Tumor Necrosis Factor Ligand and Receptor Families
1996 StandoutNobel
Inhibition of the Caenorhabditis elegans cell-death protease CED-3 by a CED-3 cleavage site in baculovirus p35 protein
1995 StandoutNatureNobel
β-Arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking
2001 StandoutNobel
Diffusion of nucleoside triphosphates and role of the entry site to the RNA polymerase II active center
2004 StandoutNobel
Ribozyme cleavage of telomerase mRNA sensitizes breast epithelial cells to inhibitors of topoisomerase.
2001
Structural basis of transcription: α-Amanitin–RNA polymerase II cocrystal at 2.8 Å resolution
2002 StandoutNobel
The Structure of a Complex of Recombinant Hirudin and Human α-Thrombin
1990 ScienceNobel
Chemical Glycobiology
2001 StandoutScienceNobel
Catalytic iron-carbene intermediate revealed in a cytochrome c carbene transferase
2018 StandoutNobel
Serpin reactive center loop mobility is required for inhibitor function but not for enzyme recognition.
1994
Prevention of Apoptosis by Bcl-2: Release of Cytochrome c from Mitochondria Blocked
1997 StandoutScience
Tuning P450 Enzymes as Oxidation Catalysts
2012
Genes and pathways downstream of telomerase in melanoma metastasis
2006 StandoutNobel
Functional Role of Type I and Type II Interferons in Antiviral Defense
1994 StandoutScience
Structural Basis of Transcription: An RNA Polymerase II Elongation Complex at 3.3 Å Resolution
2001 StandoutScienceNobel
A Novel Type of Monoheme Cytochrome c: Biochemical and Structural Characterization at 1.23 Å Resolution of Rhodothermus marinus Cytochrome c
2008
NF-κB Antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to Suppress Caspase-8 Activation
1998 StandoutScience
One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products
2000 Standout
Death Receptors: Signaling and Modulation
1998 StandoutScience
Unique features of the trophoblast interferons
1991
Distinct Roles of the Adenovirus E4 ORF3 Protein in Viral DNA Replication and Inhibition of Genome Concatenation
2003
Crystal structure of the thrombin-hirudin complex: a novel mode of serine protease inhibition.
1990
Intrinsically Disordered Proteins in Human Diseases: Introducing the D2Concept
2008
Fas Preassociation Required for Apoptosis Signaling and Dominant Inhibition by Pathogenic Mutations
2000 StandoutScienceNobel
Chemomimetic Biocatalysis: Exploiting the Synthetic Potential of Cofactor-Dependent Enzymes To Create New Catalysts
2015 StandoutNobel
Differential Carbohydrate Recognition of Two GlcNAc-6-sulfotransferases with Possible Roles in L-Selectin Ligand Biosynthesis
2000 StandoutNobel
A general strategy to construct small molecule biosensors in eukaryotes
2015 StandoutNobel
A cell protection screen reveals potent inhibitors of multiple stages of the hepatitis C virus life cycle
2010 StandoutNobel
Architecture of RNA Polymerase II and Implications for the Transcription Mechanism
2000 StandoutScienceNobel
Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1
2003
A simplified system for generating recombinant adenoviruses
1998 Standout
Selectin−Carbohydrate Interactions: From Natural Ligands to Designed Mimics
1998
Protein-Protein Interactions between Hepatitis C Virus Nonstructural Proteins
2003
Structural Basis of Transcription: RNA Polymerase II at 2.8 Ångstrom Resolution
2001 StandoutScienceNobel
Design of Heme Enzymes with a Tunable Substrate Binding Pocket Adjacent to an Open Metal Coordination Site
2023 StandoutNobel
Enzyme-Controlled Nitrogen-Atom Transfer Enables Regiodivergent C–H Amination
2014 StandoutNobel
Works of Eric Degryse being referenced
Total biosynthesis of hydrocortisone from a simple carbon source in yeast
2003
Probing the limits of expression levels by varying promoter strength and plasmid copy number in Saccharomyces cerevisiae
1996
Self-sufficient biosynthesis of pregnenolone and progesterone in engineered yeast
1998
EVIDENCE FOR EXTENDED MAINTENANCE OF THE CORPUS LUTEUM BY UTERINE INFUSION OF A RECOMBINANT TROPHOBLAST α-INTERFERON (TROPHOBLASTIN) IN SHEEP
1990
Inhibitory activity and conformational transition of α1‐proteinase inhibitor variants
1991 Nobel
Point mutations modifying the thrombin inhibition kinetics and antithrombotic activity in vivo of recombinant hirudin
1989
In vivo intermolecular recombination in Escherichia coli: application to plasmid constructions
1996
Conversion of recombinant hirudin to the natural form by in vitro tyrosine sulfation. Differential substrate specificities of leech and bovine tyrosylprotein sulfotransferases.
1990
Cloning and expression of a cDNA coding for the anticoagulant hirudin from the bloodsucking leech, Hirudo medicinalis.
1986
Efficient generation of recombinant adenovirus vectors by homologous recombination in Escherichia coli
1996
A comparative analysis of extreme thermophilic bacteria belonging to the genus Thermus
1978