Citation Impact
Citing Papers
Activity-Dependent Internalization of Smoothened Mediated by ß-Arrestin 2 and GRK2
2004 StandoutScienceNobel
High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
2007 StandoutScienceNobel
Dishevelled 2 Recruits ß-Arrestin 2 to Mediate Wnt5A-Stimulated Endocytosis of Frizzled 4
2003 StandoutScienceNobel
Spinophilin Blocks Arrestin Actions in Vitro and in Vivo at G Protein-Coupled Receptors
2004 StandoutScienceNobel
Keeping G Proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and Gßγ
2003 StandoutScienceNobel
Mechanisms of Aging of the Extracellular Matrix: Role of the Elastin-Laminin Receptor
1998
Antibody specificity and immunoglobulin VH utilization of human monoclonal CD5+ B cell lines
1991
Alterations in cardiac adrenergic signaling and calcium cycling differentially affect the progression of cardiomyopathy
2001 StandoutNobel
Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A
1997 StandoutNatureNobel
Proteins regulating Ras and its relatives
1993 StandoutNature
Genetic manipulation of myocardial ?-adrenergic receptor activation and desensitization
2004
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
2003 StandoutNatureNobel
Effect of Different G Protein-coupled Receptor Kinases on Phosphorylation and Desensitization of the α1B-Adrenergic Receptor
1996
Human Immunoglobulin Heavy-Chain Variable Region Genes: Organization, Polymorphism, and Expression
1991
A Peptide Derived from a β2-Adrenergic Receptor Transmembrane Domain Inhibits Both Receptor Dimerization and Activation
1996
High-resolution crystal structure of human protease-activated receptor 1
2012 StandoutNatureNobel
Role of G-Protein-Coupled Receptor Kinase 2 in the Heart—Do Regulatory Mechanisms Open Novel Therapeutic Perspectives?
2006
Anti–β1-adrenergic receptor antibodies and heart failure: causation, not just correlation
2004 StandoutNobel
Regulation of G Protein-Coupled Receptor Kinases and Arrestins During Receptor Desensitization
2003 StandoutNobel
Regulation of tyrosine kinase activation and granule release through β-arrestin by CXCR1
2000
The Biologic Significance of Human Natural Autoimmune Responses: Relationship to the Germline, Early Immune and Malignant B Cell Variable Gene Repertoire
1990
Protease‐activated receptors in hemostasis, thrombosis and vascular biology
2005
Direct evidence for a β1-adrenergic receptor–directed autoimmune attack as a cause of idiopathic dilated cardiomyopathy
2004
Spontaneous β2-Adrenergic Signaling Fails To Modulate L-Type Ca2+Current in Mouse Ventricular Myocytes
1999
Phosphorylation and Desensitization of the Human β1-Adrenergic Receptor
1995 StandoutNobel
Regulation of β-Adrenergic Receptor Signaling by S-Nitrosylation of G-Protein-Coupled Receptor Kinase 2
2007 StandoutNobel
Chemokine receptors: Structure, function and role in microbial pathogenesis
1996
Molecular cloning of a human immunoglobulin heavy chain variable (V ) region with anti-myelin-associated glycoprotein activity
1990
A β-arrestin 2 Signaling Complex Mediates Lithium Action on Behavior
2008 StandoutNobel
A new human immunoglobulin VH family preferentially rearranged in immature B-cell tumours
1988 Nature
The structure and function of G-protein-coupled receptors
2009 StandoutNatureNobel
The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
1992 Standout
The small GTP-binding protein rac regulates growth factor-induced membrane ruffling
1992 Standout
An Akt/β-Arrestin 2/PP2A Signaling Complex Mediates Dopaminergic Neurotransmission and Behavior
2005 StandoutNobel
Ras-dependent Mitogen-activated Protein Kinase Activation by G Protein-coupled Receptors
1997 StandoutNobel
β-Adrenergic Receptor Kinase-1 Levels in Catecholamine-Induced Myocardial Hypertrophy
1999 StandoutNobel
Fibulin-5/DANCE is essential for elastogenesis in vivo
2002 StandoutNatureNobel
B cells of chronic lymphatic leukemia express V genes in unmutated form
1991
Autoantibodies and the Fetal Antibody Repertoire
1990
Regulation of myocardial βARK1 expression in catecholamine-induced cardiac hypertrophy in transgenic mice overexpressing α1B-adrenergic receptors
2001 StandoutNobel
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
2012 StandoutNatureNobel
The complete nucleotide sequences of the heavy chain variable regions of six monospecific rheumatoid factors derived from Epstein-Barr virus-transformed B cells isolated from the synovial tissue of patients with rheumatoid arthritis. Further evidence that some autoantibodies are unmutated copies of germ line genes.
1990
Immunoglobulin heavy chain variable region family usage is independent of tumor cell phenotype in human B lineage leukemias
1990
Rho and Rac Take Center Stage
2004 Standout
The repertoire of human germline vH sequences reveals about fifty groups of VH segments with different hypervariable loops
1992 StandoutNobel
Seven-transmembrane-spanning receptors and heart function
2002 StandoutNatureNobel
VHGenes of Human Autoantibodies
1990
Myocardial G Protein‐Coupled Receptor Kinases: Implications for Heart Failure Therapy
1999
Macrophage-tropic HIV and SIV envelope proteins induce a signal through the CCR5 chemokine receptor
1997 StandoutNatureNobel
From Human Autoantibodies to the Fetal Antibody Repertoire to B Cell Malignancy: It's a Small World After All
1990
Restricted diversity of the variable region nucleotide sequences of the heavy and light chains of a human rheumatoid factor
1991
Inhibition of Spontaneous β2-Adrenergic Activation Rescues β1-Adrenergic Contractile Response in Cardiomyocytes Overexpressing β2-Adrenoceptor
2000 StandoutNobel
A 16/6 idiotype—positive anti‐DNA antibody is encoded by a conserved VH gene with no somatic mutation
1988
Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme
2000 StandoutNobel
Inhibition of receptor-localized PI3K preserves cardiac β-adrenergic receptor function and ameliorates pressure overload heart failure
2003
Differential Regulation of Dopamine D1A Receptor Responsiveness by Various G Protein-coupled Receptor Kinases
1996 StandoutNobel
A novel role for RhoGDI as an inhibitor of GAP proteins.
1993
Enhanced Morphine Analgesia in Mice Lacking β-Arrestin 2
1999 StandoutScienceNobel
Small GTP-Binding Proteins
2001 Standout
Defective lymphocyte chemotaxis in β-arrestin2- and GRK6-deficient mice
2002 StandoutNobel
β-Arrestin-Dependent Formation of β 2 Adrenergic Receptor-Src Protein Kinase Complexes
1999 StandoutScienceNobel
A GDP Dissociation Inhibitor That Serves as a GTPase Inhibitor for the Ras-Like Protein CDC42Hs
1992 Science
Targeting G βγ signaling in arterial vascular smooth muscle proliferation: A novel strategy to limit restenosis
1999 StandoutNobel
Functional Consequences of Altering Myocardial Adrenergic Receptor Signaling
2000 StandoutNobel
μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence
2000 StandoutNatureNobel
Coupling of β2-Adrenoceptor to GiProteins and Its Physiological Relevance in Murine Cardiac Myocytes
1999 StandoutNobel
Green Fluorescent Protein (GFP)-tagged Cysteine-rich Domains from Protein Kinase C as Fluorescent Indicators for Diacylglycerol Signaling in Living Cells
1998
β-Arrestin 2: A Receptor-Regulated MAPK Scaffold for the Activation of JNK3
2000 StandoutScienceNobel
Recent Advances in Cardiac β2-Adrenergic Signal Transduction
1999
Targeting the Receptor-G q Interface to Inhibit in Vivo Pressure Overload Myocardial Hypertrophy
1998 StandoutScienceNobel
Characterization of a guanine nucleotide dissociation stimulator for a ras-related GTPase.
1993
Molecular β-adrenergic signaling abnormalities in failing rabbit hearts after infarction
1999
Intracoronary Adenovirus-Mediated Delivery and Overexpression of the β 2 -Adrenergic Receptor in the Heart
2000 StandoutNobel
G PROTEIN–COUPLED RECEPTOR KINASES
1998 StandoutNobel
Role of β-adrenergic receptor signaling and desensitization in heart failure: new concepts and prospects for treatment
2006
Progression from hypertrophic to dilated cardiomyopathy in mice that express a mutant myosin transgene
2001
Anti–β1-adrenergic receptor antibodies and heart failure: causation, not just correlation
2004 StandoutNobel
Antagonism of Catecholamine Receptor Signaling by Expression of Cytoplasmic Domains of the Receptors
1993 StandoutScienceNobel
Human rheumatoid B-1a (CD5+ B) cells make somatically hypermutated high affinity IgM rheumatoid factors.
1993
Post-translational processing of rac p21s is important both for their interaction with the GDP/GTP exchange proteins and for their activation of NADPH oxidase.
1992
Relationship of variable region genes expressed by a human B cell lymphoma secreting pathologic anti-Pr2 erythrocyte autoantibodies.
1989
Direct evidence for a β1-adrenergic receptor–directed autoimmune attack as a cause of idiopathic dilated cardiomyopathy
2004
Somatic mutations in the variable regions of a human IgG anti-double-stranded DNA autoantibody suggest a role for antigen in the induction of systemic lupus erythematosus.
1991
In Vivo Inhibition of Elevated Myocardial β-Adrenergic Receptor Kinase Activity in Hybrid Transgenic Mice Restores Normal β-Adrenergic Signaling and Function
1999 StandoutNobel
Catecholamines, Cardiac β-Adrenergic Receptors, and Heart Failure
2000 StandoutNobel
Seeing the Machinery of Live Cells
1998 StandoutScienceNobel
Hybrid Transgenic Mice Reveal In Vivo Specificity of G Protein–Coupled Receptor Kinases in the Heart
2000 StandoutNobel
The Myocardial β-Adrenergic System in Spontaneously Hypertensive Heart Failure (SHHF) Rats
1999
Preservation of myocardial β-adrenergic receptor signaling delays the development of heart failure after myocardial infarction
2000 StandoutNobel
ß-Arrestin 2 Mediates Endocytosis of Type III TGF-ß Receptor and Down-Regulation of Its Signaling
2003 StandoutScienceNobel
Transduction of Receptor Signals by ß-Arrestins
2005 StandoutScienceNobel
GDP dissociation inhibitor prevents intrinsic and GTPase activating protein-stimulated GTP hydrolysis by the Rac GTP-binding protein.
1993
Inhibition of G protein-coupled receptor signaling by expression of cytoplasmic domains of the receptor.
1994 StandoutNobel
Works of Eric D. Tomhave being referenced
Age-associated reductions in cardiac beta1- and beta2-adrenergic responses without changes in inhibitory G proteins or receptor kinases.
1998
Regulation of Human Interleukin-8 Receptor A: Identification of a Phosphorylation Site Involved in Modulating Receptor Functions
1995
Rac1, a low‐molecular‐mass GTP‐binding‐protein with high intrinsic GTPase activity and distinct biochemical properties
1992
Both stimulatory and inhibitory exchange proteins, smg GDS and rho GDI, are active on multiple small GTP-binding proteins
1992
Thrombin Primes Responsiveness of Selective Chemoattractant Receptors at a Site Distal to G Protein Activation
1996
Developmentally restricted immunoglobulin heavy chain variable region gene expressed at high frequency in chronic lymphocytic leukemia.
1989
Regulation of stably transfected platelet activating factor receptor in RBL-2H3 cells. Role of multiple G proteins and receptor phosphorylation.
1994
Myocardial overexpression of GRK3 in transgenic mice: evidence for in vivo selectivity of GRKs
1998
Autoantibody-associated kappa light chain variable region gene expressed in chronic lymphocytic leukemia with little or no somatic mutation. Implications for etiology and immunotherapy.
1988
Reciprocal In Vivo Regulation of Myocardial G Protein–Coupled Receptor Kinase Expression by β-Adrenergic Receptor Stimulation and Blockade
1998 StandoutNobel
Receptor class desensitization of leukocyte chemoattractant receptors.
1991
Differences in phosphorylation of formylpeptide and C5a chemoattractant receptors correlate with differences in desensitization.
1993
Cross-desensitization of receptors for peptide chemoattractants. Characterization of a new form of leukocyte regulation.
1994
High-frequency expression of a conserved kappa light-chain variable-region gene in chronic lymphocytic leukemia.
1987