Standout Papers
Citation Impact
Citing Papers
Targeting of Cyclic AMP Degradation to β 2 -Adrenergic Receptors by β-Arrestins
2002 StandoutScienceNobel
Myomegalin Is a Novel Protein of the Golgi/Centrosome That Interacts with a Cyclic Nucleotide Phosphodiesterase
2001
Phosphodiesterase 4D and Protein Kinase A Type II Constitute a Signaling Unit in the Centrosomal Area
2001
The Wellcome Lecture, 1992. Cell cycle control
1993 StandoutNobel
Small GTP-Binding Proteins
1992
A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion
1993 StandoutNobel
Regulation of progression through the Gl phase of the cell cycle by the rum1+ gene
1994 StandoutNatureNobel
Cyclin activation of p34cdc2
1990
Ordering S phase and M phase in the cell cycle
1994 StandoutNobel
p25rum1 orders S phase and mitosis by acting as an inhibitor of the p34cdc2 mitotic kinase
1995 StandoutNobel
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
2003 StandoutNatureNobel
Regulation of the Cdk inhibitor p27 and its deregulation in cancer
2000
Evidence for an Interaction between Ubiquitin-Conjugating Enzymes and the 26S Proteasome
2000
Three-Dimensional Structure of an Evolutionarily Conserved N-Terminal Domain of Syntaxin 1A
1998 StandoutNobel
Rab GTPases in vesicular transport
1993
Subunit interaction maps for the regulatory particle of the 26S proteasome and the COP9 signalosome
2001
The small GTPases Rab5a, Rab5b and Rab5c are differentially phosphorylated in vitro
1999
A rab protein is required for the assembly of SNARE complexes in the docking of transport vesicles
1994 StandoutNobel
The FT210 cell line is a mouse G2 phase mutant with a temperature-sensitive CDC2 gene product
1990 StandoutNobel
Coupling M phase and S phase: Controls maintaining the dependence of mitosis on chromosome replication
1991 StandoutNobel
Characterization of GAPCenA, a GTPase activating protein for Rab6, part of which associates with the centrosome
1999
Involvement of p34cdc2 in establishing the dependency of S phase on mitosis
1991 StandoutNatureNobel
Synaptic transmission: A bidirectional and self-modifiable form of cell-cell communication
1993 StandoutNobel
Relationship of CDK-activating kinase and RNA polymerase II CTD kinase TFIIH/TFIIK
1994 StandoutNobel
Rab GTPases as coordinators of vesicle traffic
2009 Standout
A Long Twentieth Century of the Cell Cycle and Beyond
2000 StandoutNobel
Activity and Regulation of the Centrosome-associated Proteasome
2000
Nob1p, a new essential protein, associates with the 26S proteasome of growing Saccharomyces cerevisiae cells
2000
Human wee1 maintains mitotic timing by protecting the nucleus from cytoplasmically activated cdc2 kinase
1993
The karyogamy gene KAR2 and novel proteins are required for ER-membrane fusion
1994 StandoutNobel
Regulation of Transcription by Ubiquitination without Proteolysis
2000
The small GTP-binding protein Rab3A regulates a late step in synaptic vesicle fusion
1997 StandoutNatureNobel
Triggering of cyclin degradation in interphase extracts of amphibian eggs by cdc2 kinase
1990 StandoutNatureNobel
Distinct nuclear and spindle pole body populations of cyclin–cdc2 in fission yeast
1990 Nature
Purification of component A of Rab geranylgeranyl transferase: Possible identity with the choroideremia gene product
1992 StandoutNobel
p73 is a human p53-related protein that can induce apoptosis
1997 StandoutNatureNobel
Role of Rab GTPases in Membrane Traffic
1997
Substrates for p34cdc2: In vivo veritas?
1990 StandoutNobel
The mos proto‐oncogene product: Its role in oocyte maturation, metaphase arrest, and neoplastic transformation
1992
The fission yeast cdc18+ gene product couples S phase to START and mitosis
1993 StandoutNobel
Molecular architecture of the nerve terminal
1991
twine, a cdc25 homolog that functions in the male and female germline of drosophila
1992 StandoutNobel
Identification of a Gl-type cyclin puc1+ in the fission yeast Schizosaccharomyces pombe
1991 StandoutNatureNobel
Cic1, an adaptor protein specifically linking the 26S proteasome to its substrate, the SCF component Cdc4
2001
Regulation of mitosis by cyclic accumulation of p80cdc25 mitotic inducer in fission yeast
1990 StandoutNatureNobel
A 20s complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B
1995
Yeast as a model system for understanding the control of DNA replication in eukaryotes
1990 StandoutNobel
Cut2 proteolysis required for sister-chromatid separation in fission yeast
1996 StandoutNatureNobel
The role of Rab3A in neurotransmitter release
1994 StandoutNatureNobel
Mechanisms of intracellular protein transport
1994 StandoutNatureNobel
Universal control mechanism regulating onset of M-phase
1990 StandoutNatureNobel
Temporal order of S phase and mitosis in fission yeast is determined by the state of the p34cdc2-mitotic B cyclin complex
1994 StandoutNobel
The Florey Lecture, 1990 How is the cell division cycle regulated?
1991 StandoutNobel
p63cdc13, a B-type cyclin, is associated with both the nucleolar and chromatin domains of the fission yeast nucleus.
1993
A pre-start checkpoint preventing mitosis in fission yeast acts independently of p34cdc2 tyrosine phosphorylation.
1995 StandoutNobel
GTP hydrolysis is required for vesicle fusion during nuclear envelope assembly in vitro.
1992
Cytokinetic failure and asynchronous nuclear division in BHK cells overexpressing a truncated protein-tyrosine-phosphatase.
1992 StandoutNobel
Small GTP-Binding Proteins
2001 Standout
Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists
1999 StandoutNobel
Cyclin B interaction with microtubule-associated protein 4 (MAP4) targets p34cdc2 kinase to microtubules and is a potential regulator of M-phase microtubule dynamics.
1995
Membrane fusion machinery: Insights from synaptic proteins
1993 StandoutNobel
Checkpoints and spindles
1991 StandoutNatureNobel
Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport.
1991
The small GTP-binding protein rab4 is associated with early endosomes.
1991
Identification of a novel vertebrate cyclin: cyclin B3 shares properties with both A- and B-type cyclins.
1994
Regulation of the cell cycle by the cdk2 protein kinase in cultured human fibroblasts.
1993
Complementation of the Mitotic Activator, p80 cdc25 , by a Human Protein-tyrosine Phosphatase
1990 StandoutScienceNobel
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Mutations of p34cdc2 phosphorylation sites induce premature mitotic events in HeLa cells: evidence for a double block to p34cdc2 kinase activation in vertebrates.
1991
Cyclin B2-null mice develop normally and are fertile whereas cyclin B1-null mice die in utero
1998 StandoutNobel
Correction: Identification of a Gl-type cyclin puc+ in the fission yeast Schizosaccharomyces pombe
1991 StandoutNatureNobel
The Prognostic Significance of Altered Cyclin-Dependent Kinase Inhibitors in Human Cancer
1999
Rab7 Activation by Growth Factor Withdrawal Contributes to the Induction of Apoptosis
2009
Dominant-negative cyclin-selective ubiquitin carrier protein E2-C/UbcH10 blocks cells in metaphase
1997 StandoutNobel
The Incredible Life and Times of Biological Cells
2000 StandoutScienceNobel
Human cyclins B1 and B2 are localized to strikingly different structures: B1 to microtubules, B2 primarily to the Golgi apparatus.
1995
The requirements for protein synthesis and degradation, and the control of destruction of cyclins A and B in the meiotic and mitotic cell cycles of the clam embryo.
1992 StandoutNobel
Cyclin B targets p34cdc2 for tyrosine phosphorylation.
1991
HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53
2003 StandoutNobel
Cyclins A and B associate with chromatin and the polar regions of spindles, respectively, and do not undergo complete degradation at anaphase in syncytial Drosophila embryos.
1992
Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis.
1994 StandoutNobel
rab GTP-binding proteins with three different carboxyl-terminal cysteine motifs are modified in vivo by 20-carbon isoprenoids.
1992
Delayed cyclin A and B1 degradation in non-transformed mammalian cells
1995
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Specific association of an M-phase kinase with isolated mitotic spindles and identification of two of its substrates as MAP4 and MAP1B.
1991
The GTPase Rab3a negatively controls calcium-dependent exocytosis in neuroendocrine cells.
1994
Transforming Growth Factor β Stabilizes p15INK4B Protein, Increases p15INK4B-cdk4 Complexes, and Inhibits Cyclin D1-cdk4 Association in Human Mammary Epithelial Cells
1997
THE UBIQUITIN SYSTEM
1998 StandoutNobel
Association of p34cdc2/cyclin B complex with microtubules in starfish oocytes
1993
An inhibitor of yeast cyclin-dependent protein kinase plays an important role in ensuring the genomic integrity of daughter cells.
1994
Reversible phosphorylation--dephosphorylation determines the localization of rab4 during the cell cycle.
1992
The molecular machinery for secretion is conserved from yeast to neurons.
1993
Proteasomal Proteomics: Identification of Nucleotide-sensitive Proteasome-interacting Proteins by Mass Spectrometric Analysis of Affinity-purified Proteasomes
2000
Reversible phosphorylation controls the activity of cyclosome-associated cyclin-ubiquitin ligase.
1995 StandoutNobel
p40MO15, a cdc2-related protein kinase involved in negative regulation of meiotic maturation of Xenopus oocytes.
1990
Works of Éric Bailly being referenced
Phosphorylation of two small GTP-binding proteins of the Rab family by p34cdc2
1991 Nature
Cyclin-dependent kinase and Cks/Suc1 interact with the proteasome in yeast to control proteolysis of M-phase targets
1999
G1 control in mammalian cells
1994
Cytoplasmic accumulation of cyclin B1 in human cells: Association with a detergent-resistant compartment and with the centrosome
1992
p34cdc2 is located in both nucleus and cytoplasm; part is centrosomally associated at G2/M and enters vesicles at anaphase.
1989 StandoutNobel
Functional Characterization of Rpn3 Uncovers a Distinct 19S Proteasomal Subunit Requirement for Ubiquitin-Dependent Proteolysis of Cell Cycle Regulatory Proteins in Budding Yeast
1999