Citation Impact
Citing Papers
Interaction with Cellular CD4 Exposes HIV-1 Envelope Epitopes Targeted by Antibody-Dependent Cell-Mediated Cytotoxicity
2013
Maturation-Dependent HIV-1 Surface Protein Redistribution Revealed by Fluorescence Nanoscopy
2012 StandoutScienceNobel
Loss of a Tyrosine-Dependent Trafficking Motif in the Simian Immunodeficiency Virus Envelope Cytoplasmic Tail Spares Mucosal CD4 Cells but Does Not Prevent Disease Progression
2012
Caenorhabditis elegans ADAR editing and the ERI-6/7/MOV10 RNAi pathway silence endogenous viral elements and LTR retrotransposons
2020 StandoutNobel
Viral protein U counteracts a human host cell restriction that inhibits HIV-1 particle production
2003
Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
2013 StandoutNobel
Proteomics of HCV virions reveals an essential role for the nucleoporin Nup98 in virus morphogenesis
2016 StandoutNobel
LGP2 is a positive regulator of RIG-I– and MDA5-mediated antiviral responses
2010
The Vpu-regulated endocytosis of HIV-1 Gag is clathrin-independent
2007
Human Immunodeficiency Virus, Restriction Factors, and Interferon
2009
Expression of HIV-1 Envelope Glycoproteins by Semliki Forest Virus Vectors
1993
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
The frantic play of the concealed HIV envelope cytoplasmic tail
2013
Three-dimensional tracking of single mRNA particles in Saccharomyces cerevisiae using a double-helix point spread function
2010 StandoutNobel
HIV-1 rev regulation involves recognition of non-Watson-Crick base pairs in viral RNA
1991 StandoutNobel
Identification of an ion channel activity of the Vpu transmembrane domain and its involvement in the regulation of virus release from HIV‐1‐infected cells
1996
Roles for endocytosis in lentiviral replication
1997
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
2020 Standout
Ion channel activity of HIV-1 Vpu is dispensable for counteraction of CD317
2011
Reaching for high-hanging fruit in drug discovery at protein–protein interfaces
2007 StandoutNature
The cytoplasmic body component TRIM5α restricts HIV-1 infection in Old World monkeys
2004 StandoutNature
Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu
2008 StandoutNature
mRNA Is an Endogenous Ligand for Toll-like Receptor 3
2004 StandoutNobel
Completion of the entire hepatitis C virus life cycle in genetically humanized mice
2013 StandoutNatureNobel
The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer
2018
Identification of RNA Binding Proteins Associated with Dengue Virus RNA in Infected Cells Reveals Temporally Distinct Host Factor Requirements
2016
An Interferon-α-Induced Tethering Mechanism Inhibits HIV-1 and Ebola Virus Particle Release but Is Counteracted by the HIV-1 Vpu Protein
2007
Unraveling the functions of plasmacytoid dendritic cells during viral infections, autoimmunity, and tolerance
2010
HIV-1 Vpu Promotes Release and Prevents Endocytosis of Nascent Retrovirus Particles from the Plasma Membrane
2006
HIV-1 Vpu — an ion channel in search of a job
2013
Pattern Recognition Receptors and Inflammation
2010 Standout
Viral channel proteins in intracellular protein–protein communication: Vpu of HIV-1, E5 of HPV16 and p7 of HCV
2013
Simultaneous Transport of Different Localized mRNA Species Revealed by Live‐Cell Imaging
2008
HIV accessory proteins as therapeutic targets
1997
Fruit bats as reservoirs of Ebola virus
2005 StandoutNature
Screening of the Pan-African Natural Product Library Identifies Ixoratannin A-2 and Boldine as Novel HIV-1 Inhibitors
2015 StandoutNobel
Cell type‐dependence for Vpu function
1994
Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein
2002 StandoutNature
HIV-1 Vpr Triggers Natural Killer Cell–Mediated Lysis of Infected Cells through Activation of the ATR-Mediated DNA Damage Response
2009
Interaction of Retroviral Reverse Transcriptase with Template–Primer Duplexes during Replication
1997
The Simian Immunodeficiency Virus Envelope Glycoprotein Contains Multiple Signals that Regulate its Cell Surface Expression and Endocytosis
2000
Ebola virus entry requires the cholesterol transporter Niemann–Pick C1
2011 StandoutNature
A Serpin Shapes the Extracellular Environment to Prevent Influenza A Virus Maturation
2015 StandoutNobel
Intrinsic Immunity Shapes Viral Resistance of Stem Cells
2017 StandoutNobel
The membrane-proximal intracytoplasmic tyrosine residue of HIV-1 envelope glycoprotein is critical for basolateral targeting of viral budding in MDCK cells
1997
Mitochondrion-mediated apoptosis in HIV-1 infection
2003
MX2 is an interferon-induced inhibitor of HIV-1 infection
2013 StandoutNatureNobel
Antagonists of protein–protein interactions
2000
Nuclear import by karyopherin-βs: Recognition and inhibition
2010
Protein dislocation from the ER
2010
Deletion of the vpu Sequences prior to the env in a Simian–Human Immunodeficiency Virus Results in Enhanced Env Precursor Synthesis but Is Less Pathogenic for Pig-Tailed Macaques
2002
HIV as the cause of AIDS
1996 StandoutNobel
A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
Construction and In Vitro Properties of HIV-1 Mutants with Deletions in "Nonessential" Genes
1994
Increased surface expression of HIV-1 envelope is associated with improved antibody response in vaccinia prime/protein boost immunization
2017 StandoutNobel
Construction and In Vitro Properties of SIV mac Mutants with Deletions in "Nonessential" Genes
1994
Pathogenesis of Ebola Hemorrhagic Fever in Cynomolgus Macaques
2003
Ligand-protein docking studies of potential HIV-1 drug compounds using the algorithm FlexX
2010
Programmed Cell Death as a Mechanism of CD4 and CD8 T Cell Deletion in AIDS: Molecular Control and Effect of Highly Active Anti‐retroviral Therapy
1999 StandoutNobel
Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo
1997 Standout
Characterization of an HIV-2-related virus with a smaller sized extracellular envelope glycoprotein
1989 StandoutNobel
A Membrane-proximal Tyrosine-based Signal Mediates Internalization of the HIV-1 Envelope Glycoprotein via Interaction with the AP-2 Clathrin Adaptor
1998
Messenger-RNA-binding proteins and the messages they carry
2002
The glycoprotein of vesicular stomatitis virus promotes release of virus-like particles from tetherin-positive cells
2017
Catechins containing a galloyl moiety as potential anti-HIV-1 compounds
2012
Autophagy in immunity and inflammation
2011 StandoutNature
N6-methyladenosine-dependent RNA structural switches regulate RNA–protein interactions
2015 StandoutNature
A Novel Human WD Protein, h-βTrCP, that Interacts with HIV-1 Vpu Connects CD4 to the ER Degradation Pathway through an F-Box Motif
1998
Induction of cell differentiation by human immunodeficiency virus 1 vpr
1993
HIV accessory proteins: Leading roles for the supporting cast
1995
Construction and Characterization of a Fluorescently Labeled Infectious Human Immunodeficiency Virus Type 1 Derivative
2004
Molecular and biochemical analyses of human immunodeficiency virus type 1 vpu protein
1989
Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells
2010 StandoutNobel
Characterization of Novel Splice Variants of Zinc Finger Antiviral Protein (ZAP)
2019 StandoutNobel
The Pathophysiology of Mitochondrial Cell Death
2004 StandoutScience
Regulation of human immunodeficiency virus env expression by the rev gene product
1989
The human immunodeficiency virus type 1 vpr gene prevents cell proliferation during chronic infection
1995
The dsRNA binding protein family: critical roles, diverse cellular functions
2003
The long cytoplasmic tail of gp41 is required in a cell type-dependent manner for HIV-1 envelope glycoprotein incorporation into virions
2000
The human immunodeficiency virus type 1 capsid p2 domain confers sensitivity to the cyclophilin-binding drug SDZ NIM 811
1996
In Vivo Attenuation of Simian Immunodeficiency Virus by Disruption of a Tyrosine-Dependent Sorting Signal in the Envelope Glycoprotein Cytoplasmic Tail
2001
Regulation of Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Fusion by a Membrane-Interactive Domain in the gp41 Cytoplasmic Tail
2005
Human immunodeficiency virus type 1 envelope protein endocytosis mediated by a highly conserved intrinsic internalization signal in the cytoplasmic domain of gp41 is suppressed in the presence of the Pr55gag precursor protein
1996
Importance of vpr for infection of rhesus monkeys with simian immunodeficiency virus
1993
Rbx1, a Component of the VHL Tumor Suppressor Complex and SCF Ubiquitin Ligase
1999 StandoutScienceNobel
The human immunodeficiency virus type 1 Vif protein modulates the postpenetration stability of viral nucleoprotein complexes
1996
Nuclear import and cell cycle arrest functions of the HIV-1 Vpr protein are encoded by two separate genes in HIV-2/SIV(SM).
1996
Evidence for a Functional Link between Uncoating of the Human Immunodeficiency Virus Type 1 Core and Nuclear Import of the Viral Preintegration Complex
2006
ATP-independent diffusion of double-stranded RNA binding proteins
2012 StandoutNobel
Interferon-Induced SCYL2 Limits Release of HIV-1 by Triggering PP2A-Mediated Dephosphorylation of the Viral Protein Vpu
2012
Persistent infection of macaques with simian-human immunodeficiency viruses
1995
Alphavirus-based expression vectors: strategies and applications.
1996 StandoutNobel
Highly Purified Human Immunodeficiency Virus Type 1 Reveals a Virtual Absence of Vif in Virions
1999
Human Immunodeficiency Virus Type 1 Vif Protein Is an Integral Component of an mRNP Complex of Viral RNA and Could Be Involved in the Viral RNA Folding and Packaging Process
2000
Functional role of human immunodeficiency virus type 1 vpu.
1989
The Vif protein of human and simian immunodeficiency viruses is packaged into virions and associates with viral core structures
1995
A single amino acid change in the cytoplasmic domain of the simian immunodeficiency virus transmembrane molecule increases envelope glycoprotein expression on infected cells
1995
Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
2020 StandoutScience
The broadening reach of frustrated Lewis pair chemistry
2016 StandoutScience
Activation of Alkynes with B(C6F5)3 – Boron Allylation Reagents Derived from Propargyl Esters
2013
Interactions of the Cytoplasmic Domains of Human and Simian Retroviral Transmembrane Proteins with Components of the Clathrin Adaptor Complexes Modulate Intracellular and Cell Surface Expression of Envelope Glycoproteins
1999
Thymocyte-Thymic Epithelial Cell Interaction Leads to High-Level Replication of Human Immunodeficiency Virus Exclusively in Mature CD4+CD8−CD3+Thymocytes: a Critical Role for Tumor Necrosis Factor and Interleukin-7
1999 StandoutNobel
Surface Stability and Immunogenicity of the Human Immunodeficiency Virus Envelope Glycoprotein: Role of the Cytoplasmic Domain
2004
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Envelope Glycoprotein Internalization Protects Human and Simian Immunodeficiency Virus-Infected Cells from Antibody-Dependent Cell-Mediated Cytotoxicity
2015
Domains of the human immunodeficiency virus type 1 matrix and gp41 cytoplasmic tail required for envelope incorporation into virions
1996
Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus
2006 StandoutNobel
Dissociative inhibition of dimeric enzymes. Kinetic characterization of the inhibition of HIV-1 protease by its COOH-terminal tetrapeptide
1991
Truncation of the Membrane-Spanning Domain of Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Defines Elements Required for Fusion, Incorporation, and Infectivity
2009
Critical role of reverse transcriptase in the inhibitory mechanism of CNI-H0294 on HIV-1 nuclear translocation.
1996 StandoutNobel
Importance of the nef gene for maintenance of high virus loads and for development of AIDS
1991
Antiviral Efficacy of the Novel Compound BIT225 against HIV-1 Release from Human Macrophages
2009
Role of the karyopherin pathway in human immunodeficiency virus type 1 nuclear import
1996
Structure of HIV-1 reverse transcriptase bound to an inhibitor active against mutant reverse transcriptases resistant to other nonnucleoside inhibitors
2004 StandoutNobel
Human Immunodeficiency Virus Type 1 Vif Protein Is Packaged into the Nucleoprotein Complex through an Interaction with Viral Genomic RNA
2001
The HIV-1 Envelope Glycoproteins: Fusogens, Antigens, and Immunogens
1998 StandoutScience
The Vpu protein of human immunodeficiency virus type 1 forms cation-selective ion channels
1996
A Molecular Imaging Primer: Modalities, Imaging Agents, and Applications
2012
The Trojan exosome hypothesis
2003
Inhibitors of human immunodeficiency virus integrase.
1993 StandoutNobel
In Vivo Gene Delivery and Stable Transduction of Nondividing Cells by a Lentiviral Vector
1996 StandoutScience
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
VPX mutants of HIV-2 are infectious in established cell lines but display a severe defect in peripheral blood lymphocytes.
1989 StandoutNobel
Vpu and Tsg101 Regulate Intracellular Targeting of the Human Immunodeficiency Virus Type 1 Core Protein Precursor Pr55 gag
2006
Human immunodeficiency virus type 1 Vpr induces apoptosis following cell cycle arrest
1997
Potential New Anti-Human Immunodeficiency Virus Type 1 Compounds Depress Virus Replication in Cultured Human Macrophages
2004
The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade
2020
Deficiency of Niemann-Pick Type C-1 Protein Impairs Release of Human Immunodeficiency Virus Type 1 and Results in Gag Accumulation in Late Endosomal/Lysosomal Compartments
2009
Unique double-ring structure of the peroxisomal Pex1/Pex6 ATPase complex revealed by cryo-electron microscopy
2015 StandoutNobel
The human immunodeficiency virus type 1-specific protein vpu is required for efficient virus maturation and release
1990
Metabolic labeling enables selective photocrosslinking of O-GlcNAc-modified proteins to their binding partners
2012 StandoutNobel
Vpu Increases Susceptibility of Human Immunodeficiency Virus Type 1-Infected Cells to Fas Killing
1999
Genetic Dissection of the Host Tropism of Human-Tropic Pathogens
2015
An internalization signal in the simian immunodeficiency virus transmembrane protein cytoplasmic domain modulates expression of envelope glycoproteins on the cell surface.
1996
The Highly Conserved C-Terminal Dileucine Motif in the Cytosolic Domain of the Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Is Critical for Its Association with the AP-1 Clathrin Adapter
2001
Works of Éric A. Cohen being referenced
The effect of vpu on HIV-1-induced syncytia formation.
1993
Requirements for the selective degradation of CD4 receptor molecules by the human immunodeficiency virus type 1 Vpu protein in the endoplasmic reticulum
2007
Recent Advances in the Understanding of HIV-1 Vpu Accessory Protein Functions
2004
HIV‐1 Vpu Antagonizes BST‐2 by Interfering Mainly with the Trafficking of Newly Synthesized BST‐2 to the Cell Surface
2011
HIV Nef and Vpu protect HIV-infected CD4+ T cells from antibody-mediated cell lysis through down-modulation of CD4 and BST2
2014
Vpu Exerts a Positive Effect on HIV-1 Infectivity by Down-modulating CD4 Receptor Molecules at the Surface of HIV-1-producing Cells
2003
Structural and Functional Analysis of the Membrane-Spanning Domain of the Human Immunodeficiency Virus Type 1 Vpu Protein
1998
Stable Expression of the Transfected HIV-1 env Gene in a Human B Cell Line: Characterization of gp120-Expressing Clones and Immunobiological Studies
1993
Role of envelope processing and gp41 membrane spanning domain in the formation of human immunodeficiency virus type 1 (HIV-1) fusion–competent envelope glycoprotein complex
2006
In VitroCharacterization of Purified Human Thymic Dendritic Cells Infected with Human Immunodeficiency Virus Type 1
1996
Vpr R77Q is associated with long-term nonprogressive HIV infection and impaired induction of apoptosis
2003
Effects of Vpu Expression onXenopusOocyte Membrane Conductance
1998
Antagonism of Tetherin Restriction of HIV-1 Release by Vpu Involves Binding and Sequestration of the Restriction Factor in a Perinuclear Compartment
2010
Degradation of CD4 Induced by Human Immunodeficiency Virus Type 1 Vpu Protein: A Predicted Alpha-Helix Structure in the Proximal Cytoplasmic Region of CD4 Contributes to Vpu Sensitivity
1995
Human immunodeficiency virus type 1 vpr protein transactivation function: mechanism and identification of domains involved
1998
HIV-1 Vpr Causes Neuronal Apoptosis andIn VivoNeurodegeneration
2007
Identification of a protein encoded by the vpu gene of HIV-1
1988 Nature
Genome-wide RNAi Screen Reveals a New Role of a WNT/CTNNB1 Signaling Pathway as Negative Regulator of Virus-induced Innate Immune Responses
2013
Characterization of the Cytotoxic Factor(s) Released from Thymic Dendritic Cells upon Human Immunodeficiency Virus Type 1 Infection
1998
Molecular biology of the human immunodeficiency virus accessory proteins
1994
Productive Human Immunodeficiency Virus Type 1 Assembly Takes Place at the Plasma Membrane
2007
Functional Analysis of the Phosphorylation Sites on the Human Immunodeficiency Virus Type 1 Vpu Protein
1995
Envelope glycoprotein and CD4 independence of vpu-facilitated human immunodeficiency virus type 1 capsid export
1992
Vpr Stimulates Viral Expression and Induces Cell Killing in Human Immunodeficiency Virus Type 1-Infected Dividing Jurkat T Cells
1998
RNA Trafficking Signals in Human Immunodeficiency Virus Type 1
2001
Suppression of Tetherin-Restricting Activity upon Human Immunodeficiency Virus Type 1 Particle Release Correlates with Localization of Vpu in the trans -Golgi Network
2009
Vpu protein of human immunodeficiency virus type 1 enhances the release of capsids produced by gag gene constructs of widely divergent retroviruses.
1993
Polarized Human Immunodeficiency Virus Budding in Lymphocytes Involves a Tyrosine-Based Signal and Favors Cell-to-Cell Viral Transmission
1999
Major Histocompatibility Complex Class II Molecules Promote Human Immunodeficiency Virus Type 1 Assembly and Budding to Late Endosomal/Multivesicular Body Compartments
2006
The p6gag domain of human immunodeficiency virus type 1 is sufficient for the incorporation of Vpr into heterologous viral particles
1995
Human immunodeficiency virus vpr product is a virion-associated regulatory protein
1990
Importin α3 Interacts with HIV-1 Integrase and Contributes to HIV-1 Nuclear Import and Replication
2010
Two distinct oncornaviruses harbor an intracytoplasmic tyrosine-based basolateral targeting signal in their viral envelope glycoprotein
1997
Identification of tRNAs incorporated into wild-type and mutant human immunodeficiency virus type 1
1993
Requirement of the Pr55gag precursor for incorporation of the Vpr product into human immunodeficiency virus type 1 viral particles
1994
Putative alpha-helical structures in the human immunodeficiency virus type 1 Vpu protein and CD4 are involved in binding and degradation of the CD4 molecule
1997
Assessment of the Role of the Central DNA Flap in Human Immunodeficiency Virus Type 1 Replication by Using a Single-Cycle Replication System
2004
HIV-1 Vpr up-regulates expression of ligands for the activating NKG2D receptor and promotes NK cell–mediated killing
2009
Difunctional enols of N-protected amino acids as low molecular weight and novel inhibitors of HIV-1 protease.
1993
Neuroinflammation-Induced Interactions between Protease-Activated Receptor 1 and Proprotein Convertases in HIV-Associated Neurocognitive Disorder
2015
Specific inhibition of herpesvirus ribonucleotide reductase by a nonapeptide derived from the carboxy terminus of subunit 2
1986 Nature
The intracytoplasmic domain of gp41 mediates polarized budding of human immunodeficiency virus type 1 in MDCK cells
1994
Mutagenic analysis of human immunodeficiency virus type 1 Vpr: role of a predicted N-terminal alpha-helical structure in Vpr nuclear localization and virion incorporation
1995
The Double-Stranded RNA-Binding Protein Staufen Is Incorporated in Human Immunodeficiency Virus Type 1: Evidence for a Role in Genomic RNA Encapsidation
2000