Citation Impact
Citing Papers
Molecular Analysis of Commensal Host-Microbial Relationships in the Intestine
2001 StandoutScience
A Sulfilimine Bond Identified in Collagen IV
2009 StandoutScienceNobel
The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins
2013 StandoutScienceNobel
Structural Roles for Human Translation Factor eIF3 in Initiation of Protein Synthesis
2005 StandoutScienceNobel
Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists
2024 StandoutScienceNobel
Structure of eIF3b RNA Recognition Motif and Its Interaction with eIF3j
2006
The Indispensable N-Terminal Half of eIF3j/HCR1 Cooperates with its Structurally Conserved Binding Partner eIF3b/PRT1-RRM and with eIF1A in Stringent AUG Selection
2010
Translation Initiation Factor eIF4G-1 Binds to eIF3 through the eIF3e Subunit
2006
Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice
2009
Rotavirus RNA-binding protein NSP3 interacts with eIF4GI and evicts the poly(A) binding protein from eIF4F
1998
Initiation of translation in prokaryotes and eukaryotes
1999
The NEDD8 Pathway Is Essential for SCFβ-TrCP-mediated Ubiquitination and Processing of the NF-κB Precursor p105
2002 StandoutNobel
Structural basis for the enhancement of eIF4A helicase activity by eIF4G
2005
Selective Uptake of Cytosolic, Peroxisomal, and Plasma Membrane Proteins into the Yeast Lysosome for Degradation
1996 StandoutNobel
The FGF family: biology, pathophysiology and therapy
2009 Standout
Formation of the ∼350-kDa Apg12-Apg5·Apg16 Multimeric Complex, Mediated by Apg16 Oligomerization, Is Essential for Autophagy in Yeast
2002 StandoutNobel
Autoinhibitory Interdomain Interactions and Subfamily-specific Extensions Redefine the Catalytic Core of the Human DEAD-box Protein DDX3
2015 StandoutNobel
Functional Overlap between eIF4G Isoforms in Saccharomyces cerevisiae
2010 StandoutNobel
eIF4E activity is regulated at multiple levels
1999
RNA-binding activity of translation initiation factor eIF4G1 from Saccharomyces cerevisiae
2003
Autophagy regulates lipid metabolism
2009 StandoutNature
The Cryo-EM Structure of a Translation Initiation Complex from Escherichia coli
2005 StandoutNobel
4E-BP3, a New Member of the Eukaryotic Initiation Factor 4E-binding Protein Family
1998
Vaccinia Virus Protein Synthesis Has a Low Requirement for the Intact Translation Initiation Factor eIF4F, the Cap-Binding Complex, within Infected Cells
1998
Insulin Stimulates Hypoxia-inducible Factor 1 through a Phosphatidylinositol 3-Kinase/Target of Rapamycin-dependent Signaling Pathway
2002 StandoutNobel
Systemic Fluorescence Imaging of Zebrafish Glycans with Bioorthogonal Chemistry
2015 StandoutNobel
An mRNA m7G Cap Binding-like Motif within Human Ago2 Represses Translation
2007
Adipocytes as regulators of energy balance and glucose homeostasis
2006 StandoutNature
Hepatitis-C-virus-like internal ribosome entry sites displace eIF3 to gain access to the 40S subunit
2013 StandoutNatureNobel
Cap-Dependent Translation Initiation in Eukaryotes Is Regulated by a Molecular Mimic of eIF4G
1999
Identification and Characterization of a Novel Cap-binding Protein from Arabidopsis thaliana
1998
Identification of stop codon readthrough genes in Saccharomyces cerevisiae
2003
A three-dimensional view of the molecular machinery of RNA interference
2008 StandoutNatureNobel
The Human Protein HSPC021 Interacts with Int-6 and Is Associated with Eukaryotic Translation Initiation Factor 3
2001
Two subcellular localizations of eIF3 p170 and its interaction with membrane-bound microfilaments: implications for alternative functions of p170
2001
Insulin-like Growth Factor 1 Induces Hypoxia-inducible Factor 1-mediated Vascular Endothelial Growth Factor Expression, Which is Dependent on MAP Kinase and Phosphatidylinositol 3-Kinase Signaling in Colon Cancer Cells
2002 StandoutNobel
Using the Acropora digitifera genome to understand coral responses to environmental change
2011 StandoutNature
Two RNA-binding motifs in eIF3 direct HCV IRES-dependent translation
2013 StandoutNobel
C1q and its growing family
2006
Polyamines Regulate Both Transcription and Translation of the Gene Encoding Ornithine Decarboxylase Antizyme in Mouse
1997
Catabolite inactivation of fructose‐1,6‐bisphosphatase in yeast is mediated by the proteasome
1994
Interaction of Translation Initiation Factor eIF4G with eIF4A in the Yeast Saccharomyces cerevisiae
1999
Interaction of polyadenylate-binding protein with the eIF4G homologue PAIP enhances translation
1998 Nature
Fibroblast growth factor signalling: from development to cancer
2010 Standout
Extracellular matrix structure
2015 Standout
The 26S proteasome of the yeast Saccharomyces cerevisiae
1994 StandoutNobel
Processing of p105 Is Inhibited by Docking of p50 Active Subunits to the Ankyrin Repeat Domain, and Inhibition Is Alleviated by Signaling via the Carboxyl-terminal Phosphorylation/ Ubiquitin-Ligase Binding Domain
2001 StandoutNobel
Crystal Structure of NC1 Domains
2002
Conservation and diversity in the structure of translation initiaton factor eIF3 from humans and yeast
1996
Characterization of cDNAs Encoding the p44 and p35 Subunits of Human Translation Initiation Factor eIF3
1998
The structure and proteolytic processing of Cbln1 complexes
2005
Spectrin Domain of Eukaryotic Initiation Factor 3a Is the Docking Site for Formation of the a:b:i:g Subcomplex
2013
Structure of mammalian eIF3 in the context of the 43S preinitiation complex
2015 StandoutNatureNobel
C1q and tumor necrosis factor superfamily: modularity and versatility
2004
Degradation of Ornithine Decarboxylase by the 26S Proteasome
2000
Cooperative modulation by eIF4G of eIF4E-binding to the mRNA 5' cap in yeast involves a site partially shared by p20
1998
Complex Formation by All Five Homologues of Mammalian Translation Initiation Factor 3 Subunits from Yeast Saccharomyces cerevisiae
1998
Insulin signalling and the regulation of glucose and lipid metabolism
2001 StandoutNature
Essential role for the alpha 1 chain of type VIII collagen in Zebrafish notochord formation
2008
Conservation and Diversity of Eukaryotic Translation Initiation Factor eIF3
1997
Internal Ribosome Entry Sites in Cellular mRNAs: Mystery of Their Existence
2005
Reconstitution reveals the functional core of mammalian eIF3
2007
Dual Function of eIF3j/Hcr1p in Processing 20 S Pre-rRNA and Translation Initiation
2001
PCI complexes: pretty complex interactions in diverse signaling pathways
2001
eIF3: a versatile scaffold for translation initiation complexes
2006
The Arabidopsis homologue of an eIF3 complex subunit associates with the COP9 complex1
1998
Signaling, Internalization, and Intracellular Activity of Fibroblast Growth Factor
2004
The Saccharomyces cerevisiae HCR1 Gene Encoding a Homologue of the p35 Subunit of Human Translation Initiation Factor 3 (eIF3) Is a High Copy Suppressor of a Temperature-sensitive Mutation in the Rpg1p Subunit of Yeast eIF3
1999
Stem Cell-derived Neural Stem/Progenitor Cell Supporting Factor Is an Autocrine/Paracrine Survival Factor for Adult Neural Stem/Progenitor Cells
2003 StandoutNobel
A newly identified N-terminal amino acid sequence of human eIF4G binds poly(A)-binding protein and functions in poly(A)-dependent translation
1998
Proteolytic and lipolytic responses to starvation
2006
Mammalian MAP kinase signalling cascades
2001 StandoutNature
eIF4G Functionally Differs from eIFiso4G in Promoting Internal Initiation, Cap-independent Translation, and Translation of Structured mRNAs
2001
Structure of 20S proteasome from yeast at 2.4Å resolution
1997 StandoutNatureNobel
Functional analysis of the interaction between HCV 5'UTR and putative subunits of eukaryotic translation initiation factor eIF3
1998
Depletion of the cap-associated isoform of translation factor eIF4G induces germline apoptosis in C. elegans
2008
Biophysical Studies of eIF4E Cap-binding Protein: Recognition of mRNA 5′ Cap Structure and Synthetic Fragments of eIF4G and 4E-BP1 Proteins
2002
Functional consequences of developmentally regulated alternative splicing
2011
The mRNA 5′ cap-binding protein eIF4E and control of cell growth
1998
Characterization of eIF3k
2003
Compagen, a comparative genomics platform for early branching metazoan animals, reveals early origins of genes regulating stem‐cell differentiation
2008
Translation initiation and viral tricks
2003
Molecular interaction between human tumor marker protein p150, the largest subunit of eIF3, and intermediate filament protein K7
2001
Mutant fibroblast growth factor receptor 3 induces intracellular signaling and cellular transformation in a cell type- and mutation-specific manner
2009
eIF4E expression in tumors: its possible role in progression of malignancies
1999
Molecular mechanisms and clinical applications of angiogenesis
2011 StandoutNature
Structural and functional similarities between the central eukaryotic initiation factor (eIF)4A-binding domain of mammalian eIF4G and the eIF4A-binding domain of yeast eIF4G
2001
Changes in integrity and association of eukaryotic protein synthesis initiation factors during apoptosis
2000
The Crystal Structure of the Costimulatory OX40-OX40L Complex
2006
Related eIF3 subunits TIF32 and HCR1 interact with an RNA recognition motif in PRT1 required for eIF3 integrity and ribosome binding
2001
The j-Subunit of Human Translation Initiation Factor eIF3 Is Required for the Stable Binding of eIF3 and Its Subcomplexes to 40 S Ribosomal Subunits in Vitro
2004 StandoutNobel
Structure of the Mammalian Ribosomal 43S Preinitiation Complex Bound to the Scanning Factor DHX29
2013 StandoutNobel
Cap-dependent eukaryotic initiation factor-mRNA interactions probed by cross-linking
2008
Eukaryotic Translation Initiation Factor 4G Is Targeted for Proteolytic Cleavage by Caspase 3 during Inhibition of Translation in Apoptotic Cells
1998
Targeting the Extracellular Domain of Fibroblast Growth Factor Receptor 3 with Human Single-Chain Fv Antibodies Inhibits Bladder Carcinoma Cell Line Proliferation
2005
A Conserved HEAT Domain within eIF4G Directs Assembly of the Translation Initiation Machinery
2001
The Cambrian Conundrum: Early Divergence and Later Ecological Success in the Early History of Animals
2011 StandoutScience
eIF4 Initiation Factors: Effectors of mRNA Recruitment to Ribosomes and Regulators of Translation
1999 Standout
eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation
2016 StandoutNatureNobel
Phosphorylation of the Cap-Binding Protein Eukaryotic Translation Initiation Factor 4E by Protein Kinase Mnk1 In Vivo
1999
Rapamycin and Wortmannin Enhance Replication of a Defective Encephalomyocarditis Virus
1998
Proteasomes: destruction as a programme
1996
Proteolysis of human eukaryotic translation initiation factor eIF4GII, but not eIF4GI, coincides with the shutoff of host protein synthesis after poliovirus infection
1998
The cell-adhesion G protein-coupled receptor BAI3 is a high-affinity receptor for C1q-like proteins
2011 StandoutNobel
Changes in Ribosomal Binding Activity of eIF3 Correlate with Increased Translation Rates during Activation of T Lymphocytes
2005
Multiple Myeloma
2010
Eukaryotic Initiation Factor 4GII (eIF4GII), but Not eIF4GI, Cleavage Correlates with Inhibition of Host Cell Protein Synthesis after Human Rhinovirus Infection
1999
Antitumor activity of fibroblast growth factor receptor 3–specific immunotoxins in a xenograft mouse model of bladder carcinoma is mediated by apoptosis
2008
The NMR–Rosetta capsid model of M13 bacteriophage reveals a quadrupled hydrophobic packing epitope
2015 StandoutNobel
Specific Isoforms of Translation Initiation Factor 4GI Show Differences in Translational Activity
2006
Hydroxylation of the eukaryotic ribosomal decoding center affects translational accuracy
2014 StandoutNobel
New Ways of Initiating Translation in Eukaryotes?
2001
Cancer Genome Landscapes
2013 StandoutScience
Identification of a Translation Initiation Factor 3 (eIF3) Core Complex, Conserved in Yeast and Mammals, That Interacts with eIF5
1998
T-cadherin is a receptor for hexameric and high-molecular-weight forms of Acrp30/adiponectin
2004
Identification in the Ancient Protist Giardia lamblia of Two Eukaryotic Translation Initiation Factor 4E Homologues with Distinctive Functions
2005
Hepatitis C Virus IRES RNA-Induced Changes in the Conformation of the 40 S Ribosomal Subunit
2001 StandoutScienceNobel
Degradation of Ornithine Decarboxylase by the Mammalian and Yeast 26S Proteasome Complexes Requires all the Components of the Protease
1995 StandoutNobel
Universal conservation in translation initiation revealed by human and archaeal homologs of bacterial translation initiation factor IF2
1999
Structural Motifs Involved in Ubiquitin-Mediated Processing of the NF-κB Precursor p105: Roles of the Glycine-Rich Region and a Downstream Ubiquitination Domain
1999 StandoutNobel
Specific Interaction of Eukaryotic Translation Initiation Factor 3 with the 5′ Nontranslated Regions of Hepatitis C Virus and Classical Swine Fever Virus RNAs
1998
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Functional reconstitution of human eukaryotic translation initiation factor 3 (eIF3)
2011 StandoutNobel
Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3
2008 StandoutNobel
THE UBIQUITIN SYSTEM
1998 StandoutNobel
Fibroblast Growth Factor Receptor 1 Promotes Proliferation and Survival via Activation of the Mitogen-Activated Protein Kinase Pathway in Bladder Cancer
2009
Eukaryotic translation initiation factor 4GI and p97 promote cellular internal ribosome entry sequence-driven translation
2005
The target of rapamycin (TOR) proteins
2001
Human eukaryotic translation initiation factor 4G (eIF4G) recruits Mnk1 to phosphorylate eIF4E
1999
Filamentous Phage Display in the New Millennium
2005
Cap-Independent Translation Is Required for Starvation-Induced Differentiation in Yeast
2007 StandoutScienceNobel
Coordinated assembly of human translation initiation complexes by the hepatitis C virus internal ribosome entry site RNA
2004 StandoutNobel
Works of Eran Rom being referenced
A Novel Functional Human Eukaryotic Translation Initiation Factor 4G
1998
The Human Homologue of the Yeast Prt1 Protein Is an Integral Part of the Eukaryotic Initiation Factor 3 Complex and Interacts with p170
1997
Cloning and Characterization of 4EHP, a Novel Mammalian eIF4E-related Cap-binding Protein
1998
The 20S proteasome mediates the degradation of mouse and yeast ornithine decarboxylase in yeast cells
1994
Insight into Schmid Metaphyseal Chondrodysplasia from the Crystal Structure of the Collagen X NC1 Domain Trimer
2002
A Unified Pathway for the Degradation of Ornithine Decarboxylase in Reticulocyte Lysate Requires Interaction with the Polyamine‐Induced Protein, Ornithine Decarboxylase Antizyme
1994
FGF receptors ubiquitylation: dependence on tyrosine kinase activity and role in downregulation
2002
Fibroblast Growth Factor 4 and Its Novel Splice Isoform Have Opposing Effects on the Maintenance of Human Embryonic Stem Cell Self-Renewal
2008
Human Combinatorial Fab Library Yielding Specific and Functional Antibodies against the Human Fibroblast Growth Factor Receptor 3
2003
The inhibitory anti-FGFR3 antibody, PRO-001, is cytotoxic to t(4;14) multiple myeloma cells
2006
Polyamines regulate the expression of ornithine decarboxylase antizyme in vitro by inducing ribosomal frame-shifting.
1994