Citation Impact
Citing Papers
RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis
2009 StandoutScience
High-throughput characterization of protein–protein interactions by reprogramming yeast mating
2017 StandoutNobel
Dimers of mitochondrial ATP synthase form the permeability transition pore
2013
Mediation of Poly(ADP-Ribose) Polymerase-1-Dependent Cell Death by Apoptosis-Inducing Factor
2002 StandoutScience
Role of the c subunit of the F O ATP synthase in mitochondrial permeability transition
2013
Opening of the Mitochondrial Permeability Transition Pore Causes Depletion of Mitochondrial and Cytosolic NAD+and Is a Causative Event in the Death of Myocytes in Postischemic Reperfusion of the Heart
2001
Singlet Oxygen Produced by Photodynamic Action Causes Inactivation of the Mitochondrial Permeability Transition Pore
1997
Hallmarks of Cancer: The Next Generation
2011 Standout
The Life Span Determinant p66Shc Localizes to Mitochondria Where It Associates with Mitochondrial Heat Shock Protein 70 and Regulates Trans-membrane Potential
2004
Role of hypoxia-inducible factor in cell survival during myocardial ischemia–reperfusion
2008
Effects of permeability transition inhibition and decrease in cytochrome c content on doxorubicin toxicity in K562 cells
2005
Mitochondrial Targeted Cyclophilin D Protects Cells from Cell Death by Peptidyl Prolyl Isomerization
2002
Spermine selectively inhibits high-conductance, but not low-conductance calcium-induced permeability transition pore
2014
The permeability transition pore. Control points of a cyclosporin A-sensitive mitochondrial channel involved in cell death
1996
The Identity and Regulation of the Mitochondrial Permeability Transition Pore
2008
How the Bcl-2 family of proteins interact to regulate apoptosis
2006
Cardioprotection in the Clinical Setting
2010
Complexes between kinases, mitochondrial porin and adenylate translocator in rat brain resemble the permeability transition pore
1996
Necroptosis and its role in inflammation
2015 StandoutNature
Cyclosporin A prevents calpain activation despite increased intracellular calcium concentrations, as well as translocation of apoptosis‐inducing factor, cytochrome c and caspase‐3 activation in neurons exposed to transient hypoglycemia
2003
Cleavage of BID by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis
1998 Standout
Reduced Mitochondrial Membrane Potential and Altered Responsiveness of a Mitochondrial Membrane Megachannel in p53-Induced Senescence
1999
Mitochondrial permeability transitions: how many doors to the house?
2004
Bid acts on the permeability transition pore complex to induce apoptosis
2000
Increased apoptosis of Huntington disease lymphoblasts associated with repeat length-dependent mitochondrial depolarization
1999
Mitochondrial control of apoptosis
1997
Bcl-2 and Bax regulate the channel activity of the mitochondrial adenine nucleotide translocator
2000
Complexes between porin, hexokinase, mitochondrial creatine kinase and adenylate translocator display properties of the permeability transition pore. Implication for regulation of permeability transition by the kinases
1998
Enhancing Mitochondrial Calcium Buffering Capacity Reduces Aggregation of Misfolded SOD1 and Motor Neuron Cell Death without Extending Survival in Mouse Models of Inherited Amyotrophic Lateral Sclerosis
2013
Differences in the Activation of the Mitochondrial Permeability Transition Among Brain Regions in the Rat Correlate with Selective Vulnerability
1999
Transient and Long-Lasting Openings of the Mitochondrial Permeability Transition Pore Can Be Monitored Directly in Intact Cells by Changes in Mitochondrial Calcein Fluorescence
1999
Pharmacological manipulation of cell death: clinical applications in sight?
2005
Sanglifehrin A Acts as a Potent Inhibitor of the Mitochondrial Permeability Transition and Reperfusion Injury of the Heart by Binding to Cyclophilin-D at a Different Site from Cyclosporin A
2002
IκB-α, the NF-κB Inhibitory Subunit, Interacts with ANT, the Mitochondrial ATP/ADP Translocator
2001
Superoxide Flashes in Single Mitochondria
2008
Mitochondrial permeability transition in acute neurodegeneration
2002
Mitochondria and cell death
1999
A role for mitochondria in NLRP3 inflammasome activation
2010 StandoutNature
Ca2+-dependent Control of the Permeability Properties of the Mitochondrial Outer Membrane and Voltage-dependent Anion-selective Channel (VDAC)
2006
Mitochondrial permeability transition in Ca2+-dependent apoptosis and necrosis
2011
Cyclosporin A pretreatment in a rat model of warm ischaemia/reperfusion injury
2002
Proapoptotic multidomain Bcl-2/Bax-family proteins: mechanisms, physiological roles, and therapeutic opportunities
2006
Monoamine oxidases (MAO) in the pathogenesis of heart failure and ischemia/reperfusion injury
2010
Cell Death
2004 Standout
Hexokinase II Detachment from Mitochondria Triggers Apoptosis through the Permeability Transition Pore Independent of Voltage-Dependent Anion Channels
2008
A Distinct Pathway Remodels Mitochondrial Cristae and Mobilizes Cytochrome c during Apoptosis
2002
Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death
2005 StandoutNature
Autophagy: Renovation of Cells and Tissues
2011 Standout
Bcl-2 Family Proteins: Strategies for Overcoming Chemoresistance in Cancer
1997
Mitochondrial permeability transition in CNS trauma: Cause or effect of neuronal cell death?
2004
Endoplasmic reticulum stress and mitochondrial cell death pathways mediate A53T mutant alpha-synuclein-induced toxicity
2005
Necrotic death as a cell fate
2006
Decoding ALS: from genes to mechanism
2016 StandoutNature
Regulation of hexokinase binding to VDAC
2008
Mitochondria, Oxidants, and Aging
2005 Standout
Mitochondria Are Excitable Organelles Capable of Generating and Conveying Electrical and Calcium Signals
1997
A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter
2011 StandoutNature
Life in extreme environments
2001 StandoutNature
Apop-1, a Novel Protein Inducing Cyclophilin D-dependent but Bax/Bak-related Channel-independent Apoptosis
2006 StandoutNobel
Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization
1998
Autophagy in the Pathogenesis of Disease
2008 Standout
The Shape of Cell Death
1997
Reprogramming eukaryotic translation with ligand-responsive synthetic RNA switches
2016
On the Role of VDAC in Apoptosis: Fact and Fiction
2005
Elucidating the molecular mechanism of the permeability transition pore and its role in reperfusion injury of the heart
1998
Immunity, Inflammation, and Cancer
2010 Standout
Modulation of the mitochondrial permeability transition by cyclophilin D: Moving closer to F0–F1 ATP synthase?
2011
Control of apoptosis by IP3and ryanodine receptor driven calcium signals
2000
A reversible component of mitochondrial respiratory dysfunction in apoptosis can be rescued by exogenous cytochrome c
2001
The Mitochondrial Permeability Transition, Release of Cytochrome c and Cell Death
2001
Search-and-replace genome editing without double-strand breaks or donor DNA
2019 StandoutNature
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
Calcium, mitochondria and oxidative stress in neuronal pathology
2006
A model for p53-induced apoptosis
1997 StandoutNature
Regulated necrosis: the expanding network of non-apoptotic cell death pathways
2014
Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma
2019 Nature
Autophagy is defective in collagen VI muscular dystrophies, and its reactivation rescues myofiber degeneration
2010
Origin and physiological roles of inflammation
2008 StandoutNature
Import and processing of heart mitochondrial cyclophilin D
1999
Programmed population control by cell–cell communication and regulated killing
2004 StandoutNatureNobel
Opportunities in discovery and delivery of anticancer drugs targeting mitochondria and cancer cell metabolism☆
2009
Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities
2008 Standout
Molecular characterization of mitochondrial apoptosis-inducing factor
1999 StandoutNature
Regulation and pharmacology of the mitochondrial permeability transition pore
2009
On the origin, evolution, and nature of programmed cell death: a timeline of four billion years
2002
Mitochondrial contact sites: Their role in energy metabolism and apoptosis
2005
Oxidative Stress, Thiol Reagents, and Membrane Potential Modulate the Mitochondrial Permeability Transition by Affecting Nucleotide Binding to the Adenine Nucleotide Translocase
1997
Mitochondrial pathways for ROS formation and myocardial injury: the relevance of p66Shc and monoamine oxidase
2009
The Hallmarks of Aging
2013 Standout
Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter
2011 StandoutNature
VDAC regulation by the Bcl-2 family of proteins
2000
The Mitochondrial Effects of Small Organic Ligands of BCL-2
2006
Selective degradation of mitochondria by mitophagy
2007
Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC
1999 StandoutNature
Recent advances into the understanding of mitochondrial fission
2012
Cyclophilin D controls mitochondrial pore–dependent Ca2+ exchange, metabolic flexibility, and propensity for heart failure in mice
2010
Therapeutic peptides: Targeting the mitochondrion to modulate apoptosis
2006
Oxidation of a critical thiol residue of the adenine nucleotide translocator enforces Bcl-2-independent permeability transition pore opening and apoptosis
2000
Cytochrome c: functions beyond respiration
2008
Regulated and unregulated mitochondrial permeability transition pores: a new paradigm of pore structure and function?
2002
Mitochondria and calcium signaling
2005
A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis
2002
Necrosis, a well-orchestrated form of cell demise: Signalling cascades, important mediators and concomitant immune response
2006
Reconstituted adenine nucleotide translocase forms a channel for small molecules comparable to the mitochondrial permeability transition pore
1998
Up-regulation of Apoptosis Inhibitory Protein IAP-2 by Hypoxia
2001 StandoutNobel
The permeability transition pore complex: another view
2002
Adenine nucleotide translocator isoforms 1 and 2 are differently distributed in the mitochondrial inner membrane and have distinct affinities to cyclophilin D
2001
Mitochondrial implication in apoptosis. Towards an endosymbiont hypothesis of apoptosis evolution
1997
Cyclophilin D is required for mitochondrial removal by autophagy in cardiac cells
2010
Defects in the Ubiquitin Pathway Induce Caspase-independent Apoptosis Blocked by Bcl-2
1998 StandoutNobel
The mitochondrial permeability transition pore and cyclophilin D in cardioprotection
2011
The Functional and Neuroprotective Actions of Neu2000, a Dual-Acting Pharmacological Agent, in the Treatment of Acute Spinal Cord Injury
2009
Mitochondrial Pathways, Permeability Transition Pore, and Redox Signaling in Cardioprotection: Therapeutic Implications
2012
VDAC: The channel at the interface between mitochondria and the cytosol
2003
Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death
2001 StandoutScience
Mitochondrial Transport of Cations: Channels, Exchangers, and Permeability Transition
1999
Clues from cell metabolism
2010 StandoutNatureNobel
Bax and Bcl-xL independently regulate apoptotic changes of yeast mitochondria that require VDAC but not adenine nucleotide translocator
2000
The Pathophysiology of Mitochondrial Cell Death
2004 StandoutScience
The mitochondrial permeability transition initiates autophagy in rat hepatocytes
2001
The Bcl-2 Protein Family: Arbiters of Cell Survival
1998 StandoutScience
Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia
2005
Requirement of JNK for Stress- Induced Activation of the Cytochrome c-Mediated Death Pathway
2000 StandoutScience
Mitochondria: The Hub of Cellular Ca2+Signaling
2008
Suppression of Apoptosis by Cyclophilin D via Stabilization of Hexokinase II Mitochondrial Binding in Cancer Cells
2006
Bax and Adenine Nucleotide Translocator Cooperate in the Mitochondrial Control of Apoptosis
1998 Science
Direct demonstration of a specific interaction between cyclophilin-D and the adenine nucleotide translocase confirms their role in the mitochondrial permeability transition
1998
Prevention of Apoptosis by Bcl-2: Release of Cytochrome c from Mitochondria Blocked
1997 StandoutScience
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release
2014 Standout
Mitochondrial Fission, Fusion, and Stress
2012 StandoutScience
A pore way to die: the role of mitochondria in reperfusion injury and cardioprotection
2010
The permeability transition pore signals apoptosis by directing Bax translocation and multimerization
2002
Role of Glycogen Synthase Kinase-3β in Cardioprotection
2009
The mitochondrial permeability transition pore and its role in cell death
1999 Standout
Resveratrol, a tumor‐suppressive compound from grapes, induces apoptosis via a novel mitochondrial pathway controlled by Bcl‐2
2001
Spermidine in health and disease
2018 StandoutScience
Mitochondrial Diseases in Man and Mouse
1999 StandoutScience
The Permeability Transition Pore Complex: A Target for Apoptosis Regulation by Caspases and Bcl-2–related Proteins
1998
Bax directly induces release of cytochrome c from isolated mitochondria
1998
The Release of Cytochrome c from Mitochondria: A Primary Site for Bcl-2 Regulation of Apoptosis
1997 StandoutScience
Metabolic reprogramming and cancer progression
2020 StandoutScience
Noxa, a BH3-Only Member of the Bcl-2 Family and Candidate Mediator of p53-Induced Apoptosis
2000 StandoutScience
Mitochondria and Apoptosis
1998 StandoutScience
Bcl-2 inhibits the mitochondrial release of an apoptogenic protease.
1996
Physiologic Functions of Cyclophilin D and the Mitochondrial Permeability Transition Pore
2013
Grafted human-induced pluripotent stem-cell–derived neurospheres promote motor functional recovery after spinal cord injury in mice
2011 StandoutNobel
Mitochondrial superoxide flashes: From discovery to new controversies
2012
Apoptosis, the Role of Oxidative Stress and the Example of Solar UV Radiation
1999
Cell Survival Promoted by the Ras-MAPK Signaling Pathway by Transcription-Dependent and -Independent Mechanisms
1999 StandoutScience
Ca 2+ -Induced Apoptosis Through Calcineurin Dephosphorylation of BAD
1999 Science
Autophagy as a Regulated Pathway of Cellular Degradation
2000 StandoutScience
Regulation of Cell Death Protease Caspase-9 by Phosphorylation
1998 StandoutScience
Hypoxia-inducible factor 1 transcriptional activity in endothelial cells is required for acute phase cardioprotection induced by ischemic preconditioning
2012 StandoutNobel
Bax-induced Cytochrome C Release from Mitochondria Is Independent of the Permeability Transition Pore but Highly Dependent on Mg2+ Ions
1998
Works of Emy Basso being referenced
Cyclophilin D inactivation protects axons in experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis
2007
Properties of the Permeability Transition Pore in Mitochondria Devoid of Cyclophilin D
2005
Mitochondrial Ca2+ transport and permeability transition in zebrafish (Danio rerio)
2010
Cyclophilin D in mitochondrial pathophysiology
2009
Electrophysiological characterization of the Cyclophilin D-deleted mitochondrial permeability transition pore
2006
The mitochondrial permeability transition fromin vitroartifact to disease target
2006
Phosphate Is Essential for Inhibition of the Mitochondrial Permeability Transition Pore by Cyclosporin A and by Cyclophilin D Ablation
2008
The mitochondrial permeability transition from yeast to mammals
2010
Developmental Shift of Cyclophilin D Contribution to Hypoxic-Ischemic Brain Injury
2009
Genetic ablation of cyclophilin D rescues mitochondrial defects and prevents muscle apoptosis in collagen VI myopathic mice
2009
Cyclophilin D Modulates Mitochondrial F0F1-ATP Synthase by Interacting with the Lateral Stalk of the Complex
2009
Interactions of Cyclophilin with the Mitochondrial Inner Membrane and Regulation of the Permeability Transition Pore, a Cyclosporin A-sensitive Channel
1996
Enhancement of anxiety, facilitation of avoidance behavior, and occurrence of adult-onset obesity in mice lacking mitochondrial cyclophilin D
2008
Two modes of activation of the permeability transition pore: The role of mitochondrial cyclophilin
1997
Potential role of cyclosporin A-sensitive mitochondrial channels in ischemia-reperfusion injury.
1995
Perspectives on the mitochondrial permeability transition
1998
Two modes of activation of the permeability transition pore: The role of mitochondrial cyclophilin
1997
Biochemical and Genetic Analysis of the Mitochondrial Response of Yeast to BAX and BCL-XL
2000