Standout Papers
Citation Impact
Citing Papers
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
2018 StandoutScienceNobel
Complement drives Th17 cell differentiation and triggers autoimmune arthritis
2010 StandoutNobel
The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic T reg Cell Homeostasis
2013 StandoutScience
Innate Antiviral Responses by Means of TLR7-Mediated Recognition of Single-Stranded RNA
2004 StandoutScience
Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity
2013 Standout
Metabolic Syndrome and Altered Gut Microbiota in Mice Lacking Toll-Like Receptor 5
2010 StandoutScience
Individual intestinal symbionts induce a distinct population of RORγ + regulatory T cells
2015 Science
Sex Differences in the Gut Microbiome Drive Hormone-Dependent Regulation of Autoimmunity
2013 StandoutScience
Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle
2009
Group 3 innate lymphoid cells mediate intestinal selection of commensal bacteria–specific CD4 + T cells
2015 Science
Adjuvanticity of a synthetic cord factor analogue for subunit Mycobacterium tuberculosis vaccination requires FcRγ–Syk–Card9–dependent innate immune activation
2009
Interactions Between Commensal Fungi and the C-Type Lectin Receptor Dectin-1 Influence Colitis
2012 Science
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
Commensal bacteria protect against food allergen sensitization
2014
The Cell Biology of Phagocytosis
2011
Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells
2013 StandoutScienceNobel
Acute Gastrointestinal Infection Induces Long-Lived Microbiota-Specific T Cell Responses
2012 Science
Secretory IgA-Mediated Neutralization of Shigella flexneri Prevents Intestinal Tissue Destruction by Down-Regulating Inflammatory Circuits
2009
Involvement of the NLRP3 Inflammasome in Innate and Humoral Adaptive Immune Responses to Fungal β-Glucan
2009
Cutting Edge: Mincle Is Essential for Recognition and Adjuvanticity of the Mycobacterial Cord Factor and its Synthetic Analog Trehalose-Dibehenate
2010
Loss of T Cell and B Cell Quiescence Precedes the Onset of Microbial Flora-Dependent Wasting Disease and Intestinal Inflammation in Gimap5-Deficient Mice
2010 StandoutNobel
Macrophages and Myeloid Dendritic Cells, but Not Plasmacytoid Dendritic Cells, Produce IL-10 in Response to MyD88- and TRIF-Dependent TLR Signals, and TLR-Independent Signals
2006
Group A Streptococcus Activates Type I Interferon Production and MyD88-dependent Signaling without Involvement of TLR2, TLR4, and TLR9
2008 StandoutNobel
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
Interleukin-17-Producing γδ T Cells Selectively Expand in Response to Pathogen Products and Environmental Signals
2009
CLEC9A Is a Novel Activation C-type Lectin-like Receptor Expressed on BDCA3+ Dendritic Cells and a Subset of Monocytes
2008
The regulation of IL-10 production by immune cells
2010 Standout
Mucin dynamics and enteric pathogens
2011
New concepts in the generation and functions of IgA
2012
The Role of Syk/CARD9‐Coupled C‐Type Lectin Receptors in Immunity to Mycobacterium tuberculosis Infections
2010
Intestinal Microbial Diversity during Early-Life Colonization Shapes Long-Term IgE Levels
2013
Differential Roles of Interleukin-17A and -17F in Host Defense against Mucoepithelial Bacterial Infection and Allergic Responses
2009
Short-term and long-term effects of caesarean section on the health of women and children
2018 Standout
Intestinal homeostasis and its breakdown in inflammatory bowel disease
2011 StandoutNature
The microbiota in adaptive immune homeostasis and disease
2016 StandoutNature
Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1β production
2009
Foxp3+ Regulatory T Cells Promote T Helper 17 Cell Development In Vivo through Regulation of Interleukin-2
2011
Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function
2010
Toll-like receptor control of the adaptive immune responses
2004 Standout
Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis
2014 Standout
A cytokine-mediated link between innate immunity, inflammation, and cancer
2007 Standout
Recognition of microorganisms and activation of the immune response
2007 StandoutNature
Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis
2016 StandoutNobel
Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity
2011 Standout
Interleukin-22-Producing Natural Killer Cells and Lymphoid Tissue Inducer-like Cells in Mucosal Immunity
2009
Recognition of fungal pathogens by Toll-like receptors
2004
The roles of TLRs, RLRs and NLRs in pathogen recognition
2009
The TLR2-MyD88-NOD2-RIPK2 signalling axis regulates a balanced pro-inflammatory and IL-10-mediated anti-inflammatory cytokine response to Gram-positive cell walls
2008
Modulating vaccine responses with dendritic cells and Toll‐like receptors
2004
Intracellular Toll-like Receptors
2010 StandoutNobel
Role of the Microbiota in Immunity and Inflammation
2014 Standout
Myeloid C-type Lectin Receptors in Pathogen Recognition and Host Defense
2011
Thymus-derived regulatory T cells contribute to tolerance to commensal microbiota
2013 Nature
Eater, a Transmembrane Protein Mediating Phagocytosis of Bacterial Pathogens in Drosophila
2005 StandoutNobel
Host Remodeling of the Gut Microbiome and Metabolic Changes during Pregnancy
2012 Standout
IL-23 and Th17 cytokines in intestinal homeostasis
2008
Microbial Stimulation Fully Differentiates Monocytes to DC-SIGN/CD209+ Dendritic Cells for Immune T Cell Areas
2010 StandoutNobel
Plasmacytoid dendritic cells: sensing nucleic acids in viral infection and autoimmune diseases
2008
Innate and Adaptive Immunity Interact to Quench Microbiome Flagellar Motility in the Gut
2013
IFN-γ Suppresses IL-10 Production and Synergizes with TLR2 by Regulating GSK3 and CREB/AP-1 Proteins
2006
Toll-like receptor 3 promotes cross-priming to virus-infected cells
2005 Nature
The CD8+ dendritic cell subset
2010
Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity
2006 Nature
Segmented Filamentous Bacterium Uses Secondary and Tertiary Lymphoid Tissues to Induce Gut IgA and Specific T Helper 17 Cell Responses
2014
Enterochromaffin Cells Are Gut Chemosensors that Couple to Sensory Neural Pathways
2017 StandoutNobel
Foxp3+ T Cells Regulate Immunoglobulin A Selection and Facilitate Diversification of Bacterial Species Responsible for Immune Homeostasis
2014
Activation of the innate immune receptor Dectin-1 upon formation of a ‘phagocytic synapse’
2011 Nature
Innate immune mechanisms for recognition and uptake of Candida species
2010
Diversification of memory B cells drives the continuous adaptation of secretory antibodies to gut microbiota
2015
Taking dendritic cells into medicine
2007 StandoutNatureNobel
Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9
2008
Signalling through C-type lectin receptors: shaping immune responses
2009
Immune adaptations that maintain homeostasis with the intestinal microbiota
2010
Selective C-Rel Activation via Malt1 Controls Anti-Fungal TH-17 Immunity by Dectin-1 and Dectin-2
2011
TGF-β and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain TH-17 cell–mediated pathology
2007
TLR9-Dependent Recognition of MCMV by IPC and DC Generates Coordinated Cytokine Responses that Activate Antiviral NK Cell Function
2004
The Functional Effects of Physical Interactions among Toll-like Receptors 7, 8, and 9
2006
Pathogenesis of Flavivirus Infections: Using and Abusing the Host Cell
2009
A Homozygous CARD9 Mutation in a Family with Susceptibility to Fungal Infections
2009
Phagocytosis
2005
Viral infection switches non-plasmacytoid dendritic cells into high interferon producers
2003 Nature
Dendritic-cell control of pathogen-driven T-cell polarization
2003
Dendritic Cells In Vivo: A Key Target for a New Vaccine Science
2008 StandoutNobel
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
An Essential Role for the NLRP3 Inflammasome in Host Defense against the Human Fungal Pathogen Candida albicans
2009
Identification of a dendritic cell receptor that couples sensing of necrosis to immunity
2009 Nature
Fungal Recognition by TLR2 and Dectin-1
2007
Genetics and pathogenesis of inflammatory bowel disease
2011 StandoutNature
MyD88 Signaling in T Cells Directs IgA-Mediated Control of the Microbiota to Promote Health
2015
Dendritic cells in intestinal immune regulation
2008
Instruction of Distinct CD4 T Helper Cell Fates by Different Notch Ligands on Antigen-Presenting Cells
2004 StandoutNobel
Intestinal microbiota, evolution of the immune system and the bad reputation of pro-inflammatory immunity
2011
Control of pathogens and pathobionts by the gut microbiota
2013
Commensal Bacteroides Species Induce Colitis in Host-Genotype-Specific Fashion in a Mouse Model of Inflammatory Bowel Disease
2011
Neuro-Immune Interactions at Barrier Surfaces
2016
Intrinsic and cooperative antigen-presenting functions of dendritic-cell subsets in vivo
2007
Toll-like receptors and innate immunity
2009
C-Type Lectin DC-SIGN Modulates Toll-like Receptor Signaling via Raf-1 Kinase-Dependent Acetylation of Transcription Factor NF-κB
2007
Intestinal microbiota: Shaping local and systemic immune responses
2011
Interleukin‐10‐secreting type 1 regulatory T cells in rodents and humans
2006
Compartmentalized and systemic control of tissue immunity by commensals
2013
Immunity to fungal infections
2011 Standout
Immunoglobulin A Coating Identifies Colitogenic Bacteria in Inflammatory Bowel Disease
2014
Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence
2009 Nature
Toll-like receptors in inflammatory bowel diseases: A decade later
2010
Chapter 5 Emergence of the Th17 Pathway and Its Role in Host Defense
2008
The SYK tyrosine kinase: a crucial player in diverse biological functions
2010
Microbiota-mediated colonization resistance against intestinal pathogens
2013
Innate and Adaptive Humoral Responses Coat Distinct Commensal Bacteria with Immunoglobulin A
2015
Intraluminal Containment of Commensal Outgrowth in the Gut during Infection-Induced Dysbiosis
2013
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
Understanding and exploiting the endogenous interleukin-10/STAT3-mediated anti-inflammatory response
2006
Pathogen Recognition and Innate Immunity
2006 Standout
Innate immune recognition of infected apoptotic cells directs TH17 cell differentiation
2009 Nature
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
Coactivation of Syk Kinase and MyD88 Adaptor Protein Pathways by Bacteria Promotes Regulatory Properties of Neutrophils
2009
Regulation of the Antimicrobial Response by NLR Proteins
2011
Inflammatory monocytes regulate pathologic responses to commensals during acute gastrointestinal infection
2013
The role of interleukin-2 during homeostasis and activation of the immune system
2012
The science of adjuvants
2007
Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells
2010 StandoutNobel
Signal Regulatory Protein Molecules Are Differentially Expressed by CD8− Dendritic Cells
2006
The adaptor molecule CARD9 is essential for tuberculosis control
2010
The Th17 Pathway and Inflammatory Diseases of the Intestines, Lungs, and Skin
2011
CD4+CD25−LAG3+regulatory T cells controlled by the transcription factor Egr-2
2009 StandoutNobel
Herpes simplex virus type 1 activates murine natural interferon-producing cells through toll-like receptor 9
2003
Recognition of single-stranded RNA viruses by Toll-like receptor 7
2004
DEC-205 receptor on dendritic cells mediates presentation of HIV gag protein to CD8 + T cells in a spectrum of human MHC I haplotypes
2007 StandoutNobel
Immunologically Active Autoantigens: The Role of Toll-Like Receptors in the Development of Chronic Inflammatory Disease
2007
Intestinal Bacteria and the Regulation of Immune Cell Homeostasis
2010
Interactions Between the Microbiota and the Immune System
2012 StandoutScience
GPR15-Mediated Homing Controls Immune Homeostasis in the Large Intestine Mucosa
2013 Science
A single gene encodes multiple neuropeptides mediating a stereotyped behavior
1983 StandoutNobel
Identifying Gut Microbe–Host Phenotype Relationships Using Combinatorial Communities in Gnotobiotic Mice
2014
IL-17 and Th17 Cells
2009 Standout
Functional characterization of IgA-targeted bacterial taxa from undernourished Malawian children that produce diet-dependent enteropathy
2015
Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A
2011 StandoutNobel
TLR-Independent Induction of Dendritic Cell Maturation and Adaptive Immunity by Negative-Strand RNA Viruses
2004
The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria
2008 Standout
Cutting Edge: Generation of Splenic CD8+ and CD8− Dendritic Cell Equivalents in Fms-Like Tyrosine Kinase 3 Ligand Bone Marrow Cultures
2005
Tumor therapy in mice via antigen targeting to a novel, DC-restricted C-type lectin
2008
Inflammatory Bowel Disease
2010 Standout
Host-microbiota interactions in inflammatory bowel disease
2012
Human TLRs and IL-1Rs in Host Defense: Natural Insights from Evolutionary, Epidemiological, and Clinical Genetics
2011
Emerging Challenges in Regulatory T Cell Function and Biology
2007 StandoutScienceNobel
Found in translation: the human equivalent of mouse CD8+ dendritic cells
2010
Immunization with HIV-1 Gag Protein Conjugated to a TLR7/8 Agonist Results in the Generation of HIV-1 Gag-Specific Th1 and CD8+ T Cell Responses
2005
Cutting Edge: Cooperation of IPS-1- and TRIF-Dependent Pathways in Poly IC-Enhanced Antibody Production and Cytotoxic T Cell Responses
2008
Wound Healing: A Cellular Perspective
2018 Standout
Cutting Edge: Conventional CD8α+ Dendritic Cells Are Generally Involved in Priming CTL Immunity to Viruses
2004
Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus
2006 StandoutNobel
Herpes simplex virus type-1 induces IFN-α production via Toll-like receptor 9-dependent and -independent pathways
2004
Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease
2014 StandoutScienceNobel
Induced CD4+Foxp3+Regulatory T Cells in Immune Tolerance
2012
Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection
2004 StandoutNobel
Partial nucleotide sequence of human calcitonin precursor mRNA identifies flanking cryptic peptides
1982 Nature
The Immune Response Modifier and Toll-Like Receptor 7 Agonist S-27609 Selectively Induces IL-12 and TNF-α Production in CD11c+CD11b+CD8− Dendritic Cells
2003
HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation
2004 StandoutNobel
The microbial mimic poly IC induces durable and protective CD4+T cell immunity together with a dendritic cell targeted vaccine
2008 StandoutNobel
The Antibacterial Lectin RegIIIγ Promotes the Spatial Segregation of Microbiota and Host in the Intestine
2011 Science
Signaling Pathways Downstream of Pattern-Recognition Receptors and Their Cross Talk
2007
Works of Emma Slack being referenced
Reversible Microbial Colonization of Germ-Free Mice Reveals the Dynamics of IgA Immune Responses
2010 Science
Innate and Adaptive Immunity Cooperate Flexibly to Maintain Host-Microbiota Mutualism
2009 StandoutScienceNobel
Syk‐dependent ERK activation regulates IL‐2 and IL‐10 production by DC stimulated with zymosan
2007
The mucosal firewalls against commensal intestinal microbes
2009
Myeloid C-type lectins in innate immunity
2006
Syk-Dependent Cytokine Induction by Dectin-1 Reveals a Novel Pattern Recognition Pathway for C Type Lectins
2005
Systemic antibody responses to gut commensal bacteria during chronic HIV-1 infection
2011
Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17
2007
The Microbiota Mediates Pathogen Clearance from the Gut Lumen after Non-Typhoidal Salmonella Diarrhea
2010
Functional Flexibility of Intestinal IgA – Broadening the Fine Line
2012
Toll‐like receptor expression in murine DC subsets: lack of TLR7 expression by CD8α+ DC correlates with unresponsiveness to imidazoquinolines
2003
The habitat, double life, citizenship, and forgetfulness of IgA
2011
The functional interactions of commensal bacteria with intestinal secretory IgA
2007
Thyroid origin of Calcitonin
1964 Nature
The Liver May Act as a Firewall Mediating Mutualism Between the Host and Its Gut Commensal Microbiota
2014
Intestinal Bacterial Colonization Induces Mutualistic Regulatory T Cell Responses
2011