Standout Papers
Citation Impact
Citing Papers
T cell metabolism drives immunity
2015
Aerobic glycolysis promotes T helper 1 cell differentiation through an epigenetic mechanism
2016 Science
Vulnerabilities of PTEN – TP53 -Deficient Prostate Cancers to Compound PARP–PI3K Inhibition
2014
Integrin β 1: A Mechanosignaling Sensor Essential for Connective Tissue Deposition by Fibroblasts
2013
Hypoxic control of metastasis
2016 Science
TSC1 Activates TGF-β-Smad2/3 Signaling in Growth Arrest and Epithelial-to-Mesenchymal Transition
2015
AMPK activation inhibits the functions of myeloid-derived suppressor cells (MDSC): impact on cancer and aging
2019
Metabolic regulation of NLRP 3
2017
Altered metabolite levels in cancer: implications for tumour biology and cancer therapy
2016
Crosstalk between calcium and reactive oxygen species signaling in cancer
2017
Susceptibility to Exacerbation in Chronic Obstructive Pulmonary Disease
2010 Standout
AMPK: guardian of metabolism and mitochondrial homeostasis
2017 Standout
Mechanism and medical implications of mammalian autophagy
2018 Standout
Microbial tryptophan catabolites in health and disease
2018 Standout
Emerging concepts of T cell metabolism as a target of immunotherapy
2016
Mutant p53 induces a hypoxia transcriptional program in gastric and esophageal adenocarcinoma
2019 StandoutNobel
GPCR-Mediated Signaling of Metabolites
2017
The Body-Mass Index, Airflow Obstruction, Dyspnea, and Exercise Capacity Index in Chronic Obstructive Pulmonary Disease
2004 Standout
T Cells and Cancer: How Metabolism Shapes Immunity
2016
The NLRP3 inflammasome: molecular activation and regulation to therapeutics
2019 Standout
Phytochemicals in Cancer Treatment: From Preclinical Studies to Clinical Practice
2020 Standout
Marine natural products
2009
The biology and function of fibroblasts in cancer
2016 Standout
AMPK Protects Leukemia-Initiating Cells in Myeloid Leukemias from Metabolic Stress in the Bone Marrow
2015
Oxygen availability and metabolic adaptations
2016
Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses
2015
New insights into the mechanisms of epithelial–mesenchymal transition and implications for cancer
2018 Standout
Cancer stem cells revisited
2017 Standout
A UBE2O-AMPKα2 Axis that Promotes Tumor Initiation and Progression Offers Opportunities for Therapy
2017
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Autophagy provides metabolic substrates to maintain energy charge and nucleotide pools in Ras-driven lung cancer cells
2016
Mitochondrial control of immunity: beyond ATP
2017
AMPK Is Essential to Balance Glycolysis and Mitochondrial Metabolism to Control T-ALL Cell Stress and Survival
2016
Branched-chain amino acid transaminase 1 (BCAT1) promotes the growth of breast cancer cells through improving mTOR-mediated mitochondrial biogenesis and function
2017
PI(3,4,5)P 3 Engagement Restricts Akt Activity to Cellular Membranes
2017
An Ancient, Unified Mechanism for Metformin Growth Inhibition in C. elegans and Cancer
2016
Dicumarol inhibits PDK1 and targets multiple malignant behaviors of ovarian cancer cells
2017
Harnessing the plasticity of CD4+ T cells to treat immune-mediated disease
2016
Emerging Biological Principles of Metastasis
2017 Standout
Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression
2015 Standout
Sarcopenia
2019 Standout
The Human Knockout Gene CLYBL Connects Itaconate to Vitamin B12
2017
Current understanding of the human microbiome
2018 Standout
Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy
2017 Standout
Hypoxia: Signaling the Metastatic Cascade
2016
Application of ultrasound for muscle assessment in sarcopenia: towards standardized measurements
2018
Understanding the Intersections between Metabolism and Cancer Biology
2017 Standout
AKT/PKB Signaling: Navigating the Network
2017 Standout
Mitochondria as multifaceted regulators of cell death
2019 Standout
Acetyl-CoA Carboxylase 1-Dependent Protein Acetylation Controls Breast Cancer Metastasis and Recurrence
2017
Ferroptosis: mechanisms, biology and role in disease
2021 Standout
Mitochondrial TCA cycle metabolites control physiology and disease
2020 Standout
The PI3K Pathway in Human Disease
2017 Standout
Delayed gut microbiota development in high-risk for asthma infants is temporarily modifiable by Lactobacillus supplementation
2018
The Nature of Small-Airway Obstruction in Chronic Obstructive Pulmonary Disease
2004 Standout
Defining trained immunity and its role in health and disease
2020 Standout
Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin
2016
Reprogramming glucose metabolism in cancer: can it be exploited for cancer therapy?
2016
Management of COPD exacerbations: a European Respiratory Society/American Thoracic Society guideline
2017 Standout
Using sulfuramidimidoyl fluorides that undergo sulfur(vi) fluoride exchange for inverse drug discovery
2020 StandoutNobel
Metabolic pathways promoting cancer cell survival and growth
2015
Identification of bioactive metabolites using activity metabolomics
2019
Targeting T cell metabolism for therapy
2015
Clinical Practice Guidelines and Quality of Care for Older Patients With Multiple Comorbid Diseases
2005 Standout
L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity
2016
Reprogramming of mitochondrial metabolism by innate immunity
2018
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease
2012 Standout
Toward Understanding Success and Failures in the Use of Selenium for Cancer Prevention
2013
Tumor-infiltrating regulatory T cells as targets of cancer immunotherapy
2023 StandoutNobel
Drug Discovery and Natural Products: End of an Era or an Endless Frontier?
2009 StandoutScience
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase
2014
Immunometabolism governs dendritic cell and macrophage function
2015 Standout
Fundamentals of cancer metabolism
2016 Standout
Nonoverlapping roles of PD-1 and FoxP3 in maintaining immune tolerance in a novel autoimmune pancreatitis mouse model
2016 StandoutNobel
Drug-Induced Oxidative Stress and Toxicity
2012
Insulin Receptor Isoforms in Physiology and Disease: An Updated View
2017
Akt/PKB: one kinase, many modifications
2015
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
Bioenergetics and translational metabolism: implications for genetics, physiology and precision medicine
2019
Spermidine in health and disease
2018 StandoutScience
Oxidative Stress: An Essential Factor in the Pathogenesis of Gastrointestinal Mucosal Diseases
2014 Standout
Chimeric Antigen Receptor Therapy
2018 Standout
Wound Healing: A Cellular Perspective
2018 Standout
Metabolic reprogramming and cancer progression
2020 StandoutScience
Physical Activity and Public Health in Older Adults
2007 Standout
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
Exogenous spermine inhibits hypoxia/ischemia-induced myocardial apoptosis via regulation of mitochondrial permeability transition pore and associated pathways
2016
Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal
2014 Standout
Combination therapy strategies for improving PD‐1 blockade efficacy: a new era in cancer immunotherapy
2017 StandoutNobel
PD-1 restraint of regulatory T cell suppressive activity is critical for immune tolerance
2020
Metabolomics for Investigating Physiological and Pathophysiological Processes
2019
Inflammation and metabolism in tissue repair and regeneration
2017 StandoutScience
Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy
2016 Standout
Pulmonary rehabilitation following exacerbations of chronic obstructive pulmonary disease
2016
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Short Overview of ROS as Cell Function Regulators and Their Implications in Therapy Concepts
2019
MetaboAnalyst 5.0: narrowing the gap between raw spectra and functional insights
2021 Standout
Works of Emma E. Vincent being referenced
PDK1-Dependent Metabolic Reprogramming Dictates Metastatic Potential in Breast Cancer
2015
The Energy Sensor AMPK Regulates T Cell Metabolic Adaptation and Effector Responses In Vivo
2015
The AMP-activated protein kinase (AMPK) and cancer: Many faces of a metabolic regulator
2014
Randomized Controlled Trial of Dietary Creatine as an Adjunct Therapy to Physical Training in Chronic Obstructive Pulmonary Disease
2008
Effects of ulapualide A and synthetic macrolide analogues on actin dynamics and gene regulation
2007
Investigating the effects of lycopene and green tea on the metabolome of men at risk of prostate cancer: The ProDiet randomised controlled trial
2018
Targeting Non-Small Cell Lung Cancer Cells by Dual Inhibition of the Insulin Receptor and the Insulin-Like Growth Factor-1 Receptor
2013
Mitochondrial Phosphoenolpyruvate Carboxykinase Regulates Metabolic Adaptation and Enables Glucose-Independent Tumor Growth
2015
An early rehabilitation intervention to enhance recovery during hospital admission for an exacerbation of chronic respiratory disease: randomised controlled trial
2014
Akt signalling in health and disease
2011 Standout
The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway
2016
Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation
2016
Metformin Antagonizes Cancer Cell Proliferation by Suppressing Mitochondrial-Dependent Biosynthesis
2015
GAM: a web-service for integrated transcriptional and metabolic network analysis
2016
Bedside Assessment of Quadriceps Muscle by Ultrasound after Admission for Acute Exacerbations of Chronic Respiratory Disease
2015
Loss of the tumor suppressor LKB1 promotes metabolic reprogramming of cancer cells via HIF-1α
2014