Citation Impact
Citing Papers
Differentiation of muscle, fat, cartilage, and bone from progenitor cells present in a bone-derived clonal cell population: effect of dexamethasone.
1988
Neuronal apoptosis linked to EglN3 prolyl hydroxylase and familial pheochromocytoma genes: Developmental culling and cancer
2005 StandoutNobel
Effects of an Rb mutation in the mouse
1992 StandoutNature
The cellular 107K protein that binds to adenovirus E1A also associates with the large T antigens of SV40 and JC virus
1989
SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene
1988 Standout
Retinoblastoma protein switches the E2F site from positive to negative element
1992 Nature
Requirement for a functional Rb-1 gene in murine development
1992 Nature
Role for the p53 homologue p73 in E2F-1-induced apoptosis
2000 StandoutNatureNobel
The Petinoblastoma Tumor Suppressor Protein
1994
A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F
1992
The retinoblastoma susceptibility gene product undergoes cell cycle-dependent dephosphorylation and binding to and release from SV40 large T
1990
Oncogenes and Tumor-Suppressing Genes
1988
Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis
1992 Nature
An N-Terminal transformation-governing sequence of SV40 large T antigen contributes to the binding of both p110 and a second cellular protein, p120
1989
Retinoblastoma gene mutations in primary human bladder cancer
1995
Structure and partial genomic sequence of the human retinoblastoma susceptibility gene
1989
A new component of the transcription factor DRTF1/E2F
1993 Nature
An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor
1990
The retinoblastoma protein is phosphorylated during specific phases of the cell cycle
1989
Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties
1992 StandoutNobel
Physical interaction of the retinoblastoma protein with human D cyclins
1993
Revisions of the international criteria for neuroblastoma diagnosis, staging, and response to treatment.
1993 Standout
The Hallmarks of Cancer
2000 Standout
The Oncogenic Cysteine-rich LIM domain protein Rbtn2 is essential for erythroid development
1994 StandoutNobel
Tumor suppressor genes
1991 Standout
Cellular targets for transformation by the adenovirus E1A proteins
1989
The E2F transcription factor is a cellular target for the RB protein
1991 Standout
Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product
1988 StandoutNature
Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation
1993 Standout
Retinoblastoma in transgenic mice
1990 Nature
Role of the retinoblastoma protein in the pathogenesis of human cancer.
1997 StandoutNobel
Loss of heterozygosity at the RB locus correlates with loss of RB protein in primary malignant neuro‐endocrine lung carcinomas
1994
The T/E1A-binding domain of the retinoblastoma product can interact selectively with a sequence-specific DNA-binding protein
1991 StandoutNobel
Loss of RB protein expression in primary bladder cancer correlates with loss of heterozygosity at the RB locus and tumor progression
1993
Negative regulation of human c-fos expression by thes retinoblastoma gene product
1990 Nature
Retinoblastoma gene mutations in primary human prostate cancer
1995
Retinoblastoma gene structure and product expression in human gastric carcinomas
1994
Recent advances with liposomes as pharmaceutical carriers
2005 Standout
Oncogenic Point Mutations in the Human Retinoblastoma Gene: Their Application to Genetic Counseling
1989
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
Growth inhibition by TGF-β linked to suppression of retinoblastoma protein phosphorylation
1990
The cell cycle and the retinoblastoma protein family
1994
An analysis of abnormalities of the retinoblastoma gene in human ovarian and endometrial carcinoma
1990
Retinoblastoma cancer suppressor gene product is a substrate of the cell cycle regulator cdc2 kinase.
1991
The alternative product from the human CDKN2A locus, p14ARF, participates in a regulatory feedback loop with p53 and MDM2
1998
Identification of cellular proteins that can interact specifically with the T/ElA-binding region of the retinoblastoma gene product
1991 StandoutNobel
MyoD and the regulation of myogenesis by helix-loop-helix proteins.
1991
Molecular analysis of the retinoblastoma gene in primary ovarian cancer cells
1994
E2F-1 Functions in Mice to Promote Apoptosis and Suppress Proliferation
1996 StandoutNobel
Molecular themes in oncogenesis
1991 StandoutNobel
p73 is a human p53-related protein that can induce apoptosis
1997 StandoutNatureNobel
Ras signalling is required for inactivation of the tumour suppressor pRb cell-cycle control protein
1997
The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle
1991
Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex
2004 StandoutNatureNobel
Short Dysfunctional Telomeres Impair Tumorigenesis in the INK4aΔ2/3 Cancer-Prone Mouse
1999 StandoutNobel
Molecular cloning, chromosomal mapping, and expression of the cDNA for p107, a retinoblastoma gene product-related protein
1991
lin-35 and lin-53, Two Genes that Antagonize a C. elegans Ras Pathway, Encode Proteins Similar to Rb and Its Binding Protein RbAp48
1998 StandoutNobel
Cyclin A and the retinoblastoma gene product complex with a common transcription factor
1991 StandoutNatureNobel
G1/S phosphorylation of the retinoblastoma protein is associated with an altered affinity for the nuclear compartment
1991
The retinoblastoma protein copurifies with E2F-I, an E1A-regulated inhibitor of the transcription factor E2F
1991
Phosphorylation of CrkII Adaptor Protein at Tyrosine 221 by Epidermal Growth Factor Receptor
1998
Multilineage Potential of Adult Human Mesenchymal Stem Cells
1999 StandoutScience
Generation of Lymphohematopoietic Cells from Embryonic Stem Cells in Culture
1994 StandoutScienceNobel
Point Mutational Inactivation of the Retinoblastoma Antioncogene
1989 Science
Oncogenic point mutations in exon 20 of the RB1 gene in families showing incomplete penetrance and mild expression of the retinoblastoma phenotype.
1992
Identification of a growth suppression domain within the retinoblastoma gene product.
1992 StandoutNobel
Antibodies specific for the human retinoblastoma protein identify a family of related polypeptides.
1991
Cell cycle regulation of the human cdc2 gene.
1992
The retinoblastoma gene functions as a growth and tumor suppressor in human bladder carcinoma cells.
1991
E1A induces phosphorylation of the retinoblastoma protein independently of direct physical association between the E1A and retinoblastoma products.
1991
Definition of the Minimal Simian Virus 40 Large Τ Antigen- and Adenovirus E1A-Binding Domain in the Retinoblastoma Gene Product
1990 StandoutNobel
The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines.
1991
Direct Transcriptional Repression by pRB and Its Reversal by Specific Cyclins
1995
The E7 proteins of the nononcogenic human papillomavirus type 6b (HPV-6b) and of the oncogenic HPV-16 differ in retinoblastoma protein binding and other properties
1990
The retinoblastoma protein physically associates with the human cdc2 kinase.
1992
Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus
1990 Standout
Binding of the von Hippel-Lindau Tumor Suppressor Protein to Elongin B and C
1995 StandoutScienceNobel
Tumor Suppressor Genes
1991 Science
Expression and state of phosphorylation of the retinoblastoma susceptibility gene product in cycling and noncycling human hematopoietic cells.
1990
p53 Functions as a Cell Cycle Control Protein in Osteosarcomas
1990
Memory Suppressor Genes: Inhibitory Constraints on the Storage of Long-Term Memory
1998 StandoutScienceNobel
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Abnormalities in Structure and Expression of the Human Retinoblastoma Gene in SCLC
1988 Science
RBF, a novel RB-related gene that regulates E2F activity and interacts with cyclin E in Drosophila.
1996
The retinoblastoma protein is phosphorylated on multiple sites by human cdc2.
1991
Promoter deletion and loss of retinoblastoma gene expression in human prostate carcinoma.
1990
p53 functions as a cell cycle control protein in osteosarcomas.
1990
Altered structure and expression of the human retinoblastoma susceptibility gene in small cell lung cancer
1991
The Transcription Factor E2F-1 Is a Downstream Target of RB Action
1995 StandoutNobel
Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein.
1993
Deletion of a splice donor site ablates expression of the following exon and produces an unphosphorylated RB protein unable to bind SV40 T antigen.
1990
The retinoblastoma protein and cell cycle control
1995 Standout
Suppression of the Neoplastic Phenotype by Replacement of the RB Gene in Human Cancer Cells
1988 Science
Hyperphosphorylation of the retinoblastoma gene product is determined by domains outside the simian virus 40 large-T-antigen-binding regions.
1990
Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein.
1996 StandoutNobel
Loss of heterozygosity for the short arm of chromosome 1 in human neuroblastomas: correlation with N-myc amplification.
1989
Adenovirus E1a prevents the retinoblastoma gene product from repressing the activity of a cellular transcription factor.
1992
Regulation of retinoblastoma protein functions by ectopic expression of human cyclins
1992 Standout
Viruses in Human Cancers
1991 StandoutScienceNobel
The retinoblastoma gene product regulates Sp1-mediated transcription.
1992
The adenovirus E1A-associated 130-kD protein is encoded by a member of the retinoblastoma gene family and physically interacts with cyclins A and E.
1993
Definition of the minimal simian virus 40 large T antigen- and adenovirus E1A-binding domain in the retinoblastoma gene product.
1990 StandoutNobel
Tumor Rejection After Direct Costimulation of CD8 + T Cells by B7-Transfected Melanoma Cells
1993 StandoutScienceNobel
The Molecular Genetics of Cancer
1987 StandoutScienceNobel
Establishment of two rabbit mammary epithelial cell lines with distinct oncogenic potential and differentiated phenotype after microinjection of transforming genes.
1986
Frequent loss of heterozygosity at the retinoblastoma locus in human esophageal cancers.
1991
Nonfunctional mutants of the retinoblastoma protein are characterized by defects in phosphorylation, viral oncoprotein association, and nuclear tethering.
1991
Identification of HPV-16 E7 peptides that are potent antagonists of E7 binding to the retinoblastoma suppressor protein.
1990
Transcriptional repression by the Rb-related protein p107.
1993
Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis.
1994 StandoutNobel
Genetically encoded fluorescent reporters of protein tyrosine kinase activities in living cells
2001 StandoutNobel
Collaboration of G1 cyclins in the functional inactivation of the retinoblastoma protein.
1994
DNA tumor virus oncoproteins and retinoblastoma gene mutations share the ability to relieve the cell's requirement for cyclin D1 function in G1.
1994
Inhibition of E2F-1 Transactivation by Direct Binding of the Retinoblastoma Protein
1993
A single amino acid substitution results in a retinoblastoma protein defective in phosphorylation and oncoprotein binding.
1990
A maize cDNA encoding a member of the retinoblastoma protein family: involvement in endoreduplication.
1996 StandoutNobel
Dual roles of the retinoblastoma protein in cell cycle regulation and neuron differentiation.
1994
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
Identification of p53 Gene Mutations in Bladder Cancers and Urine Samples
1991 Science
Regulation of the Ets-Related Transcription Factor Elf-1 by Binding to the Retinoblastoma Protein
1993 StandoutScienceNobel
Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product.
1992
Two distinct and frequently mutated regions of retinoblastoma protein are required for binding to SV40 T antigen.
1990
Coexpression of messenger RNA for TRK protooncogene and low affinity nerve growth factor receptor in neuroblastoma with favorable prognosis.
1993
Inactivation of the Retinoblastoma Susceptibility Gene in Human Breast Cancers
1988 Science
Suppression of Tumorigenicity of Human Prostate Carcinoma Cells by Replacing a Mutated RB Gene
1990 Science
Cell type and differentiation dependent heterogeneity in retinoblastoma protein expression in SCID mouse fetuses.
1992
Altered expression of the cyclin D1 and retinoblastoma genes in human esophageal cancer.
1993
Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein.
1993
The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F.
1992
Works of Emil Bogenmann being referenced
Immunoliposomal fenretinide: a novel antitumoral drug for human neuroblastoma
2003
Lack of High-Affinity Nerve Growth Factor Receptors in Aggressive Neuroblastomas
1993
The RET and TRKA pathways collaborate to regulate neuroblastoma differentiation
2004
Effects of complex extracellular matrices on 5-azacytidine-induced myogenesis
1986
Frequent inactivation of the retinoblastoma anti-oncogene is restricted to a subset of human tumor cells.
1990
Expression of the MyoD1 Muscle Determination Gene Defines Differentiation Capability but Not Tumorigenicity of Human Rhabdomyosarcomas
1989
Nerve Growth Factor (NGF) Induces Neuronal Differentiation in Neuroblastoma Cells Transfected with the NGF Receptor cDNA
1990
Expression of the MyoD1 muscle determination gene defines differentiation capability but not tumorigenicity of human rhabdomyosarcomas.
1989
Nerve growth factor induces a multimeric TrkA receptor complex in neuronal cells that includes Crk, SHC and PLC-gamma 1 but excludes P130CAS.
1996
Structure and expression of the murine retinoblastoma gene and characterization of its encoded protein.
1989
Cone Cell-Specific Genes Expressed in Retinoblastoma
1988 Science
Deletions of a DNA sequence in retinoblastomas and mesenchymal tumors: organization of the sequence and its encoded protein.
1987
Effect of cell shape change on the function and differentiation of rabbit mammary cells in culture
1983