Citation Impact
Citing Papers
Deficiency in the Repair of DNA Damage by Homologous Recombination and Sensitivity to Poly(ADP-Ribose) Polymerase Inhibition
2006
ATM Activation and Its Recruitment to Damaged DNA Require Binding to the C Terminus of Nbs1
2005
C-terminal region of activation-induced cytidine deaminase (AID) is required for efficient class switch recombination and gene conversion
2014 StandoutNobel
Plants send small RNAs in extracellular vesicles to fungal pathogen to silence virulence genes
2018 StandoutScience
PARP inhibitors: Synthetic lethality in the clinic
2017 StandoutScience
Bifluoride Ion Mediated SuFEx Trifluoromethylation of Sulfonyl Fluorides and Iminosulfur Oxydifluorides
2019 StandoutNobel
The phosphorylation status of PAS‐B distinguishes HIF‐1α from HIF‐2α in NBS1 repression
2006
Sources of variation in baseline gene expression levels from toxicogenomics study control animals across multiple laboratories
2008
Hierarchical Mechanisms for Direct Reprogramming of Fibroblasts to Neurons
2013 StandoutNobel
Evidence that the Nijmegen breakage syndrome protein, an early sensor of double-strand DNA breaks (DSB), is involved in HIV-1 post-integration repair by recruiting the ataxia telangiectasia-mutated kinase in a process similar to, but distinct from, cellular DSB repair
2008
Comparative studies on the enantioselective fluorination of oxindoles with structurally modified N-fluorobenzenesulfonimides
2013
Triple-Negative Breast Cancer
2010 Standout
The DNA-damage response in human biology and disease
2009 StandoutNature
High-resolution mapping of copy-number alterations with massively parallel sequencing
2008
Tipin-Replication Protein A Interaction Mediates Chk1 Phosphorylation by ATR in Response to Genotoxic Stress
2010 StandoutNobel
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
2005 StandoutNature
Epigenetics in human disease and prospects for epigenetic therapy
2004 StandoutNature
Cell-cycle checkpoints and cancer
2004 StandoutNature
SQ/TQ cluster domains: concentrated ATM/ATR kinase phosphorylation site regions in DNA-damage-response proteins
2005
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
2005 StandoutNature
Cellular Senescence in Cancer and Aging
2007 Standout
ATM and related protein kinases: safeguarding genome integrity
2003 Standout
NBS1 Localizes to γ-H2AX Foci through Interaction with the FHA/BRCT Domain
2002
Checkpoint Failure and Chromosomal Instability without Lymphomagenesis in Mre11ATLD1/ATLD1 Mice
2003
The Human Transcription Factors
2018 Standout
Reduced Life- and Healthspan in Mice Carrying a Mono-Allelic BubR1 MVA Mutation
2012
Steroid Receptors Reprogram FoxA1 Occupancy through Dynamic Chromatin Transitions
2016
Identification of Druggable Cancer Driver Genes Amplified across TCGA Datasets
2014
Genetic Evidence for Single-Strand Lesions Initiating Nbs1-Dependent Homologous Recombination in Diversification of Ig V in Chicken B Lymphocytes
2009
A DNA damage checkpoint response in telomere-initiated senescence
2003 StandoutNature
Immunogenicity of induced pluripotent stem cells
2011 StandoutNature
Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage
2003
Tel2 mediates activation and localization of ATM/Tel1 kinase to a double-strand break
2008 StandoutNobel
Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
2011 StandoutNobel
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
Multiple functions of MRN in end-joining pathways during isotype class switching
2009
Wnt/β-Catenin Signaling and Disease
2012 Standout
Ablation of PARP-1 does not interfere with the repair of DNA double-strand breaks, but compromises the reactivation of stalled replication forks
2004
BLM is an early responder to DNA double-strand breaks
2006
Human DNA damage response and repair deficiency syndromes: Linking genomic instability and cell cycle checkpoint proficiency
2009
Pioneer transcription factors: establishing competence for gene expression
2011
Increased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan
2012
Chk2 Oligomerization Studied by Phosphopeptide Ligation
2008 StandoutNobel
Structural and Functional Versatility of the FHA Domain in DNA-Damage Signaling by the Tumor Suppressor Kinase Chk2
2002
Steady-state Regulation of the Human DNA Mismatch Repair System
2000
Requirement of Non-canonical Activity of Uracil DNA Glycosylase for Class Switch Recombination
2006 StandoutNobel
Delineation of the Role of the Mre11 Complex in Class Switch Recombination
2004
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
Nijmegen breakage syndrome gene, NBS1, and molecular links to factors for genome stability
2002
A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
Activation and regulation of ATM kinase activity in response to DNA double-strand breaks
2007
Aneuploidy Acts Both Oncogenically and as a Tumor Suppressor
2006
The MRE11 complex: at the crossroads of DNA repair and checkpoint signalling
2002
The role of senescent cells in ageing
2014 StandoutNature
The Hallmarks of Aging
2013 Standout
Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
2008 StandoutNobel
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
2016 StandoutNature
Inhibition of Poly(ADP-Ribose) Polymerase in Tumors from BRCA Mutation Carriers
2009 Standout
Tumour evolution inferred by single-cell sequencing
2011 StandoutNature
Cell cycle kinases as therapeutic targets for cancer
2009
The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator
2012 StandoutNobel
Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets
2010
Current Contributions of Organofluorine Compounds to the Agrochemical Industry
2020
Requirement of the MRN complex for ATM activation by DNA damage
2003
CLOCK:BMAL1 is a pioneer-like transcription factor
2014 StandoutNobel
p21 Both Attenuates and Drives Senescence and Aging in BubR1 Progeroid Mice
2013
MDC1 regulates intra-S-phase checkpoint by targeting NBS1 to DNA double-strand breaks
2008
Copper-Mediated Annulation of Phosphorus-Containing Arenes with Alkynes: An Approach to Phosphindolium Salts
2017
Monofluorination of Organic Compounds: 10 Years of Innovation
2015 Standout
3d Transition Metals for C–H Activation
2018 Standout
Novel interferon-β-induced gene expression in peripheral blood cells
2007
Contribution of Organofluorine Compounds to Pharmaceuticals
2020 Standout
Mechanisms of double-strand break repair in somatic mammalian cells
2009
Current and Prospective Protein Biomarkers of Lung Cancer
2017
Ataxia telangiectasia mutated (Atm) is not required for telomerase-mediated elongation of short telomeres
2006 StandoutNobel
Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage–modified chromatin
2008
Chiral N‐Fluorodibenzenesulfonimide Analogues for Enantioselective Electrophilic Fluorination and Oxidative Fluorination
2013
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites
2009
Chk2 Activation Dependence on Nbs1 after DNA Damage
2001
Enantioselective Fluorination of 2‐Oxindoles by Structure‐Micro‐Tuned N‐Fluorobenzenesulfonamides
2014
Interferon-Stimulated Genes: A Complex Web of Host Defenses
2014 StandoutNobel
Targeted Disruption of the Wnt Regulator Kremen Induces Limb Defects and High Bone Density
2008
The broadening reach of frustrated Lewis pair chemistry
2016 StandoutScience
Rapid metabolic evolution in human prefrontal cortex
2011 StandoutNobel
Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair
2008 StandoutNobel
Extrahelical (CAG)/(CTG) triplet repeat elements support proliferating cell nuclear antigen loading and MutLα endonuclease activation
2013 StandoutNobel
Per- and polyfluoroalkyl substances in the environment
2022 StandoutScience
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Histone3 lysine4 trimethylation regulated by the facilitates chromatin transcription complex is critical for DNA cleavage in class switch recombination
2010 StandoutNobel
Metal-Free Aromatic Hydrogenation: Aniline to Cyclohexyl-amine Derivatives
2012
Molecular Origin of Blood‐Based Infrared Spectroscopic Fingerprints**
2021 StandoutNobel
Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints
2004 StandoutNobel
Salinity tolerance of crops – what is the cost?
2015 Standout
A hereditary nonpolyposis colorectal carcinoma case associated with hypermethylation of the MLH1 gene in normal tissue and loss of heterozygosity of the unmethylated allele in the resulting microsatellite instability-high tumor.
2002
Works of Emi Ito being referenced
NOTCH3 Signaling Pathway Plays Crucial Roles in the Proliferation of ErbB2-Negative Human Breast Cancer Cells
2008
Expression screening of 17q12–21 amplicon reveals GRB7 as an ERBB2‐dependent oncogene
2012
Differential responses of normal human coronary artery endothelial cells against multiple cytokines comparatively assessed by gene expression profiles
2006
FAM83B is a novel biomarker for diagnosis and prognosis of lung squamous cell carcinoma
2015
The Wnt Signaling Antagonist Kremen1 is Required for Development of Thymic Architecture
2006
Influence of inhalation anesthesia assessed by comprehensive gene expression profiling
2005
Understanding the Thalidomide Chirality in Biological Processes by the Self-disproportionation of Enantiomers
2018
A membrane trafficking pathway regulated by the plant-specific RAB GTPase ARA6
2011
Promoter analysis of the human mismatch repair gene hMSH2
1998
FoxA1 as a lineage-specific oncogene in luminal type breast cancer
2007
Nbs1 is essential for DNA repair by homologous recombination in higher vertebrate cells
2002 Nature
Monoallelic BUB1B mutations and defective mitotic‐spindle checkpoint in seven families with premature chromatid separation (PCS) syndrome
2006
A Core Promoter and a Frequent Single-Nucleotide Polymorphism of the Mismatch Repair GenehMLH1
1999
The Forkhead-associated Domain of NBS1 Is Essential for Nuclear Foci Formation after Irradiation but Not Essential for hRAD50·hMRE11·NBS1 Complex DNA Repair Activity
2001
An in vivo screening system to identify tumorigenic genes
2016
Self-disproportionation of enantiomers of thalidomide and its fluorinated analogue via gravity-driven achiral chromatography: mechanistic rationale and implications
2014
Isolation and Characterization of the 5′ Region of the Human Mismatch Repair GenehPMS1
1998
Asymmetric Synthesis of Both Mirror Images of 3′-Fluorothalidomide by Enantiodivergent Fluorination Using a Single, Cinchona Alkaloid
2010
Zwitterionic Ladder Stilbenes with Phosphonium and Borate Bridges: Intramolecular Cascade Cyclization and Structure–Photophysical Properties Relationship
2011