Citation Impact
Citing Papers
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1
2007 StandoutNobel
Direct conversion of fibroblasts to functional neurons by defined factors
2010 StandoutNatureNobel
Hierarchical Mechanisms for Direct Reprogramming of Fibroblasts to Neurons
2013 StandoutNobel
Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons
1993
Focal cerebral ischemia in rats induces expression of p75 neurotrophin receptor in resistant striatal cholinergic neurons
1998
Autophagy Is Activated by Apoptotic Signalling in Sympathetic Neurons: An Alternative Mechanism of Death Execution
1999
C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation
2001 StandoutNobel
ProNGF Induces p75-Mediated Death of Oligodendrocytes following Spinal Cord Injury
2002
Molecular mechanisms of nociception
2001 StandoutNatureNobel
Analysis of any point mutation in DNA. The amplification refractory mutation system (ARMS)
1989 Standout
Severe sensory and sympathetic deficits in mice lacking neurotrophin-3
1994 Nature
Axotomy induces nerve growth factor receptor immunoreactivity in spinal motor neurons
1991
Novel roles for neurotrophins are suggested by BDNF and NT-3 mRNA expression in developing neurons
1992
Piezo2 is required for Merkel-cell mechanotransduction
2014 StandoutNatureNobel
Transneuronal regulation of neuronal specific gene expression in the mouse olfactory bulb
1990
Expression of the Cyclic AMP‐dependent Protein Kinase (PKA) Catalytic Subunit from a Herpes Simplex Virus Vector Extends the Survival of Rat Sympathetic Neurons in the Absence of NGF
1994
A capsaicin-receptor homologue with a high threshold for noxious heat
1999 StandoutNatureNobel
Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide
1999 StandoutNatureNobel
Molecular cloning of rat trkC and distribution of cells expressing messenger RNAs for members of the trk family in the rat central nervous system
1992
The ground state of embryonic stem cell self-renewal
2008 StandoutNature
Basic fibroblast growth factor released from synthetic guidance channels facilitates peripheral nerve regeneration across long nerve gaps
1989
Synaptic transmission: A bidirectional and self-modifiable form of cell-cell communication
1993 StandoutNobel
Neurotrophins and their receptors: A convergence point for many signalling pathways
2003 Standout
SM-20 Is a Novel Mitochondrial Protein That Causes Caspase-dependent Cell Death in Nerve Growth Factor-dependent Neurons
2001
Neuronal differentiation factors/cytokines and synaptic plasticity
1993
The Ras/Phosphatidylinositol 3-Kinase and Ras/ERK Pathways Function as Independent Survival Modules Each of Which Inhibits a Distinct Apoptotic Signaling Pathway in Sympathetic Neurons
2000
Expression of nerve growth factor receptor mRNA is developmentally regulated and increased after axotomy in rat spinal cord motoneurons
1989
A p75NTR and Nogo receptor complex mediates repulsive signaling by myelin-associated glycoprotein
2002
The microenvironment of the tumour–host interface
2001 StandoutNature
The Drosophila gene tailless is expressed at the embryonic termini and is a member of the steroid receptor superfamily
1990 StandoutNobel
Characterization of resiniferatoxin binding sites on sensory neurons: Co-regulation of resiniferatoxin binding and capsaicin sensitivity in adult rat dorsal root ganglia
1993
Induction of BIM, a Proapoptotic BH3-Only BCL-2 Family Member, Is Critical for Neuronal Apoptosis
2001
Expression of the SM‐20 Gene Promotes Death in Nerve Growth Factor‐Dependent Sympathetic Neurons
1999
Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition
2001 StandoutNatureNobel
In situ hybridization detection of trka mRNA in brain: Distribution, colocalization with p75NGFR and up‐regulation by nerve growth factor
1994
Nerve growth factor induces a gene homologous to the glucocorticoid receptor gene
1988
FGF signaling and target recognition in the developing xenopus visual system
1995
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
NGF and BDNF are differentially modulated by visual experience in the developing geniculocortical pathway
1995
Molecular Basis for Species-Specific Sensitivity to “Hot” Chili Peppers
2002 StandoutNobel
The menthol receptor TRPM8 is the principal detector of environmental cold
2007 StandoutNatureNobel
Neuronal Cell Death
1998
The expression, localization and functional significance of β-nerve growth factor in the central nervous system
1987
NGF Utilizes c-Ret Via a Novel GFL-Independent, Inter-RTK Signaling Mechanism to Maintain the Trophic Status of Mature Sympathetic Neurons
2002
Disruption of the low affinity receptor-binding site in NGF allows neuronal survival and differentiation by binding to the trk gene product
1992
PTEN function in mammalian cell size regulation
2002
Whisker-related neuronal patterns fail to develop in the trigeminal brainstem nuclei of NMDAR1 knockout mice
1994 Nobel
Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1
2004 StandoutNatureNobel
A motor neuron‐specific epitope and the low‐affinity nerve growth factor receptor display reciprocal patterns of during development, axotomy, and regeneration
1993
Optimized survival of hippocampal neurons in B27‐supplemented neurobasal™, a new serum‐free medium combination
1993 Standout
Induction of nerve growth factor receptor (p75NGFr) mRNA within hypoglossal motoneurons following axonal injury
1992
The TRA-1A Sex Determination Protein of C. elegans Regulates Sexually Dimorphic Cell Deaths by Repressing the egl-1 Cell Death Activator Gene
1999 StandoutNobel
Neurotrophin Binding to the p75 Receptor Modulates Rho Activity and Axonal Outgrowth
1999
Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system
1992
Differential regulation of SHC proteins by nerve growth factor in sensory neurons and PC12 cells
1998
Neurotrophin signaling through the p75 neurotrophin receptor
2002
The Tumor Necrosis Factor Ligand and Receptor Families
1996 StandoutNobel
Neurotrophins regulate dendritic growth in developing visual cortex
1995
Endocytosis of Activated TrkA: Evidence that Nerve Growth Factor Induces Formation of Signaling Endosomes
1996
Renin-angiotensin system: biochemistry and mechanisms of action.
1977 Standout
A Prosurvival Function for the p75 Receptor Death Domain Mediated via the Caspase Recruitment Domain Receptor-Interacting Protein 2
2001
Neurotrophins Induce Death of Hippocampal Neurons via the p75 Receptor
2000
Regulation of Neurotrophin-3 Expression by Epithelial-Mesenchymal Interactions: The Role of Wnt Factors
1999 StandoutScienceNobel
The Pathophysiology of Mitochondrial Cell Death
2004 StandoutScience
Neuronal life and death decisions: functional antagonism between the Trk and p75 neurotrophin receptors
1999
Work in progress: Angiotensin III - induced prostaglandin (PG) release
1976
Topographic organization of sensory projections to the olfactory bulb
1994 StandoutNobel
Tissue Engineering
1993 StandoutScience
Induction of motor neuron sprouting in vivo by ciliary neurotrophic factor and basic fibroblast growth factor
1992
A system for characterizing cellular and molecular events in programmed neuronal cell death
1993
Opposing Effects of ERK and JNK-p38 MAP Kinases on Apoptosis
1995 StandoutScience
Regressive Events in Neurogenesis
1984 Science
Caspase Inhibition Extends the Commitment to Neuronal Death Beyond Cytochrome c Release to the Point of Mitochondrial Depolarization
2000
High affinity nerve growth factor binding displays a faster rate of association than p140trk binding. Implications for multi-subunit polypeptide receptors.
1994
Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation.
1988
Regulation of neurotrophin receptors during the maturation of the mammalian visual system
1994
Hormone interactions in the isolated rabbit heart. Synthesis and coronary vasomotor effects of prostaglandins, angiotensin, and bradykinin.
1975
Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor
2002 StandoutNobel
Blockade and stimulation of renal, adrenal, and vascular angiotensin II receptors with 1-Sar, 8-Ala angiotensin II in normal man.
1976
Genetic hypertension in rats is accompanied by a defect in renal prostaglandin catabolism
1976 StandoutNatureNobel
Differentiating effects of murine nerve growth factor in the peripheral and central nervous systems of Xenopus laevis tadpoles.
1985 StandoutNobel
Classical Electrostatics in Biology and Chemistry
1995 StandoutScience
Developing dorsal root ganglion neurons require trophic support from their central processes: evidence for a role of retrogradely transported nerve growth factor from the central nervous system to the periphery.
1984
Cortical neurons express nerve growth factor receptors in advanced age and Alzheimer disease.
1992
Nerve Growth Factor Treatment After Brain Injury Prevents Neuronal Death
1987 Science
Synaptic Activity and the Construction of Cortical Circuits
1996 StandoutScience
Retrograde transport of nerve growth factor (NGF) in motoneurons of developing rats: Assessment of potential neurotrophic effects
1988
Involvement of a metalloprotease in low-affinity nerve growth factor receptor truncation: inhibition of truncation in vitro and in vivo
1993
Impaired Nociception and Pain Sensation in Mice Lacking the Capsaicin Receptor
2000 StandoutScienceNobel
EglN3 hydroxylase stabilizes BIM-EL linking VHL type 2C mutations to pheochromocytoma pathogenesis and chemotherapy resistance
2019 StandoutNobel
Vanilloid (Capsaicin) Receptors and Mechanisms
1999 Standout
Inhibition of Hyperalgesia by Ablation of Lamina I Spinal Neurons Expressing the Substance P Receptor
1997 Science
Overexpression of Nerve Growth Factor in Skin Selectively Affects the Survival and Functional Properties of Nociceptors
1999
Motor Neuron Degeneration in Mice that Express a Human Cu,Zn Superoxide Dismutase Mutation
1994 StandoutScience
Multiple endocytic pathways of G protein-coupled receptors delineated by GIT1 sensitivity
2000 StandoutNobel
Wound Healing--Aiming for Perfect Skin Regeneration
1997 StandoutScience
Neural Science
2000 StandoutNobel
Molecular probes for the development and plasticity of neural crest derivatives
1985 StandoutNobel
Stress and glucocorticoids affect the expression of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in the hippocampus
1995
Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis.
1994
Specification of Cerebral Cortical Areas
1988 StandoutScience
Angiotensin II Stimulation of Prostaglandin Production in Cultured Human Vascular Endothelium
1975 Science
Spatiotemporal dynamics of guanosine 3′,5′-cyclic monophosphate revealed by a genetically encoded, fluorescent indicator
2001 StandoutNobel
Physiology of the Neurotrophins
1996 Standout
Subcellular localization of low-affinity nerve growth factor receptor-immunoreactive protein in adult rat purkinje cells following traumatic injury
1998
Central neuronal loss and behavioral impairment in mice lacking neurotrophin receptor p75
1999
Generation of Calcium Oscillations in Fibroblasts by Positive Feedback Between Calcium and IP 3
1991 StandoutScienceNobel
DEVELOPMENT OF THE VERTEBRATE NEUROMUSCULAR JUNCTION
1999
The Molecular Biology of Axon Guidance
1996 StandoutScience
Regionally selective elimination of cutaneous thermal nociception in rats by neonatal capsaicin
1987
Enhanced Neurotrophin-Induced Axon Growth in Myelinated Portions of the CNS in Mice Lacking the p75 Neurotrophin Receptor
1999
Autophagy as a Regulated Pathway of Cellular Degradation
2000 StandoutScience
Synaptic Assembly of the Brain in the Absence of Neurotransmitter Secretion
2000 StandoutScienceNobel
Syngeneic Schwann cells derived from adult nerves seeded in semipermeable guidance channels enhance peripheral nerve regeneration
1992
NEUROTROPHINS AND SYNAPTIC PLASTICITY
1999
Profile of Circulating Vasoactive Substances in Hemorrhagic Shock and Their Pharmacologic Manipulation
1974
Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten
2004 StandoutNobel
The Nerve Growth Factor 35 Years Later
1987 StandoutScienceNobel
Activation of the Sphingomyelin Cycle Through the Low-Affinity Neurotrophin Receptor
1994 Science
Nerve growth factor increases mRNA levels for the prion protein and the beta-amyloid protein precursor in developing hamster brain.
1988 StandoutNobel
The p75 receptor transduces the signal from myelin-associated glycoprotein to Rho
2002
Mechanisms and Genes of Cellular Suicide
1995 StandoutScience
Unraveling Function in the TNF Ligand and Receptor Families
1994 StandoutScienceNobel
The p75 nerve growth factor receptor mediates survival or death depending on the stage of sensory neuron development.
1994
Axons regulate Schwann cell expression of the major myelin and NGF receptor genes
1988
Works of EM Johnson being referenced
The effects of nerve growth factor and its antiserum on the postnatal development and survival after injury of sensory neurons in rat dorsal root ganglia
1984
Retrograde transport of nerve growth factor in lesioned goldfish retinal ganglion cells
1983
Nerve growth factor receptors on cultured rat Schwann cells
1988
Cytosine arabinoside kills postmitotic neurons in a fashion resembling trophic factor deprivation: evidence that a deoxycytidine-dependent process may be required for nerve growth factor signal transduction
1990
Rapid DNA analysis of alpha 1-antitrypsin deficiency: application of an improved method for amplifying mutated gene sequences.
1988
Cytosine arabinoside kills postmitotic neurons: evidence that deoxycytidine may have a role in neuronal survival that is independent of DNA synthesis
1989
Expression of nerve growth factor receptors by Schwann cells of axotomized peripheral nerves: ultrastructural location, suppression by axonal contact, and binding properties
1988
Nerve growth factor-dependence of herpes simplex virus latency in peripheral sympathetic and sensory neurons in vitro
1990
Determinants and modification of adrenergic and vascular resistance in the kidney
1974
Retrograde transport of nerve growth factor in lesioned goldfish retinal ganglion cells.
1983
Chronic depolarization prevents programmed death of sympathetic neurons in vitro but does not support growth: requirement for Ca2+ influx but not Trk activation
1995
An immunohistochemical study of the nerve growth factor receptor in developing rats
1988
Nerve growth factor regulates sympathetic ganglion cell morphology and survival in the adult mouse
1990
Fetal NGF augmentation preserves excess trigeminal ganglion cells and interrupts whisker-related pattern formation
1994
Specific stimulation and inhibition of renal prostaglandin release by angiotensin analogs
1973
Demonstration of the retrograde transport of nerve growth factor receptor in the peripheral and central nervous system
1987
Demonstration of retrogradely transported endogenous nerve growth factor in axons of sympathetic neurons
1984
Basic fibroblast growth factor: receptor-mediated internalization, metabolism, and anterograde axonal transport in retinal ganglion cells
1990