Citation Impact
Citing Papers
Multiplex Genome Engineering Using CRISPR/Cas Systems
2013 StandoutScience
Preferential Generation of Follicular B Helper T Cells from Foxp3 + T Cells in Gut Peyer's Patches
2009 StandoutScienceNobel
A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity
2012 StandoutScienceNobel
Staphylococcus aureus RNAIII and the endoribonuclease III coordinately regulate spa gene expression
2005
Induction of CD4+ T Cell Alloantigen-Specific Hyporesponsiveness by IL-10 and TGF-β
1999
Structures of the RNA-guided surveillance complex from a bacterial immune system
2011 StandoutNatureNobel
DNA interrogation by the CRISPR RNA-guided endonuclease Cas9
2014 StandoutNatureNobel
[27] Genetic systems in Staphylococci
1991
Functional diversity of helper T lymphocytes
1996 StandoutNature
Structures of MLSBK Antibiotics Bound to Mutated Large Ribosomal Subunits Provide a Structural Explanation for Resistance
2005 StandoutNobel
The CtsR regulator of stress response is active as a dimer and specifically degraded in vivo at 37°C
2000
Drosophila genes Posterior Sex Combs and Suppressor two of zeste encode proteins with homology to the murine bmi-1 oncogene
1991 Nature
A protein binding to the Jk recombination sequence of immunoglobulin genes contains a sequence related to the integrase motif
1989 Nature
Early Transcription and Silencing of Cytokine Genes Underlie Polarization of T Helper Cell Subsets
2001
Regulatory T Cells
2000 StandoutNobel
New CRISPR–Cas systems from uncultivated microbes
2016 StandoutNatureNobel
CtsR, a novel regulator of stress and heat shock response, controls clp and molecular chaperone gene expression in Gram‐positive bacteria
1999
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
ClpE, a novel type of HSP100 ATPase, is part of the CtsR heat shock regulon of Bacillus subtilis
1999
luxABgene fusions with the arsenic and cadmium resistance operons ofStaphylococcus aureusplasmid pI258
1993
CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III
2011 StandoutNatureNobel
Molecular Events Mediating T Cell Activation
1990
Cytokine production in the central nervous system of Lewis rats with experimental autoimmune encephalomyelitis: dynamics of mRNA expression for interleukin-10, interleukin-12, cytolysin, tumor necrosis factor α and tumor necrosis factor β
1995
Cytokines Induce the Development of Functionally Heterogeneous T Helper Cell Subsets
1998
HIV-1 DNA integration: Mechanism of viral DNA cleavage and DNA strand transfer
1991
Foreign DNA capture during CRISPR–Cas adaptive immunity
2015 StandoutNatureNobel
The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA
2016 StandoutNatureNobel
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
Somatic misexpression of germline P granules and enhanced RNA interference in retinoblastoma pathway mutants
2005 StandoutNatureNobel
A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
1997 StandoutNature
RNA-guided genetic silencing systems in bacteria and archaea
2012 StandoutNatureNobel
B-cell apoptosis induced by antigen receptor crosslinking is blocked by a T-cell signal through CD40
1993 StandoutNatureNobel
XL43 and XL75: two novel RING finger-containing genes expressed during oogenesis and embryogenesis in Xenopus laevis
1998
Interleukin‐12 is required for interferon‐γ production and lethality in lipopolysaccharide‐induced shock in mice
1995
The RING finger/B-Box factor TAM-1 and a retinoblastoma-like protein LIN-35 modulate context-dependent gene silencing in Caenorhabditis elegans
1999 StandoutNobel
Biology and Applications of CRISPR Systems: Harnessing Nature’s Toolbox for Genome Engineering
2016 StandoutNobel
Instruction of Distinct CD4 T Helper Cell Fates by Different Notch Ligands on Antigen-Presenting Cells
2004 StandoutNobel
Integrase-mediated spacer acquisition during CRISPR–Cas adaptive immunity
2015 StandoutNatureNobel
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene
1996 StandoutNatureNobel
Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade
2017 StandoutNobel
The Biology of CRISPR-Cas: Backward and Forward
2018 StandoutNobel
CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
2013 StandoutNobel
Dendritic cells and the control of immunity
1998 StandoutNatureNobel
Cytokines in relapsing experimental autoimmune encephalomyelitis in DA rats: persistent mRNA expression of proinflammatory cytokines and absent expression of interleukin-10 and transforming growth factor-β
1996
Molecular definition and sequence motifs of the 52-kD component of human SS-A/Ro autoantigen.
1991
Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy
2016 StandoutNobel
Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells
1996 StandoutNatureNobel
IL-12-Deficient Mice Are Defective in IFNγ Production and Type 1 Cytokine Responses
1996
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
2016 StandoutNatureNobel
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria
2001 StandoutNatureNobel
mec-3, a homeobox-containing gene that specifies differentiation of the touch receptor neurons in C. elegans
1988 StandoutNobel
Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression
2013 StandoutNobel
Control of pT181 replication II. Mutational analysis.
1984
Viral interleukin 10 (IL-10), the human herpes virus 4 cellular IL-10 homologue, induces local anergy to allogeneic and syngeneic tumors.
1995
Antiinflammatory Effects of CD95 Ligand (FasL)-induced Apoptosis
1998
A Cas9–guide RNA complex preorganized for target DNA recognition
2015 StandoutScienceNobel
Subinhibitory Clindamycin Differentially Inhibits Transcription of Exoprotein Genes in Staphylococcus aureus
2001
The effect of antigen dose on CD4+ T helper cell phenotype development in a T cell receptor-alpha beta-transgenic model.
1995
T helper cell 1-type CD4+ T cells, but not B cells, mediate colitis in interleukin 10-deficient mice.
1996
A catenated DNA molecule as an intermediate in the replication of the resistance transfer factor R6K in Escherichia coli
1973
McsB Is a Protein Arginine Kinase That Phosphorylates and Inhibits the Heat-Shock Regulator CtsR
2009 StandoutScienceNobel
Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation.
1996 Standout
Novel Cassette-Based Shuttle Vector System for Gram-Positive Bacteria
2004 StandoutNobel
IL-12, But Not IFN-γ, Plays a Major Role in Sustaining the Chronic Phase of Colitis in IL-10-Deficient Mice
1998
CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation.
1995 StandoutNobel
Replication of Staphylococcal Multiresistance Plasmids
2000
Contingent Genetic Regulatory Events in T Lymphocyte Activation
1989 Science
Translational fusion with a secretory enzyme as an indicator
1987
Small Staphylococcus aureus plasmids are transduced as linear multimers that are formed and resolved by replicative processes
1986
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
New Vector for Efficient Allelic Replacement in Naturally Nontransformable, Low-GC-Content, Gram-Positive Bacteria
2004
Involvement of the rfp tripartite motif in protein-protein interactions and subcellular distribution
1997
Reversibility of T helper 1 and 2 populations is lost after long-term stimulation.
1996
Programmed DNA destruction by miniature CRISPR-Cas14 enzymes
2018 StandoutScienceNobel
T cell genetic background determines default T helper phenotype development in vitro.
1995
IL-12, but not IFN-gamma, plays a major role in sustaining the chronic phase of colitis in IL-10-deficient mice.
1998
Synthesis of staphylococcal virulence factors is controlled by a regulatory RNA molecule.
1993
Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4.
1995
Interleukin 12 synergizes with B7/CD28 interaction in inducing efficient proliferation and cytokine production of human T cells.
1994
The Yin and Yang of T Cell Costimulation
1995 StandoutScienceNobel
Control of pT181 replication I. The pT181 copy control function acts by inhibiting the synthesis of a replication protein.
1984
Interleukin-10 and the Interleukin-10 Receptor
2001 Standout
The future of immune checkpoint therapy
2015 StandoutScienceNobel
Molecular Mechanisms RegulatinG Th1 Immune Responses
2003
Genetic switches by DNA inversions in prokaryotes
1984
Synthesis of a Site-Specific DNA-Binding Peptide
1987 StandoutScienceNobel
Nucleotide sequence and expression of the beta-lactamase gene from Staphylococcus aureus plasmid pI258 in Escherichia coli, Bacillus subtilis, and Staphylococcus aureus
1987
Cloning and nucleotide sequence of a chromosomally encoded tetracycline resistance determinant, tetA(M), from a pathogenic, methicillin-resistant strain of Staphylococcus aureus
1990
Erythromycin resistance by ribosome modification
1995
Induction of CD4+ T cell alloantigen-specific hyporesponsiveness by IL-10 and TGF-beta.
1999
A putative zinc-binding protein on lampbrush chromosome loops.
1993
Structure, localization and transcriptional properties of two classes of retinoic acid receptor alpha fusion proteins in acute promyelocytic leukemia (APL): structural similarities with a new family of oncoproteins.
1992
An Essential Role for Interleukin 10 in the Function of Regulatory T Cells That Inhibit Intestinal Inflammation
1999
Extrachromosomal copies of transposon Tc1 in the nematode Caenorhabditis elegans.
1984
In Vivo Detection of Dendritic Cell Antigen Presentation to CD4+ T Cells
1997
Enhancement of Antitumor Immunity by CTLA-4 Blockade
1996 StandoutScienceNobel
Rewriting a genome
2013 StandoutNatureNobel
Regulation of the Ets-Related Transcription Factor Elf-1 by Binding to the Retinoblastoma Protein
1993 StandoutScienceNobel
Tn554—a site-specific represser-controlled transposon in Staphylococcus aureus
1979 Nature
Unique insertion site of Tn7 in the E. coli chromosome
1982 StandoutNatureNobel
Cloning yeast telomeres on linear plasmid vectors
1982 StandoutNobel
Interleukin-10 Is a Natural Suppressor of Cytokine Production and Inflammation in a Murine Model of Allergic Bronchopulmonary Aspergillosis
1997
Works of Ellen Murphy being referenced
Nucleotide sequence of a spectinomycin adenyltransferase AAD(9) determinant from Staphylococcus aureus and its relationship to AAD(3″) (9)
1985
Penicillinase plasmids of Staphylococcus aureus: Restriction-deletion maps
1979
Transposition of Tn554 does not generate a target duplication
1984 Nature
Nucleotide sequence of ermA, a macrolide-lincosamide-streptogramin B determinant in Staphylococcus aureus
1985
Inhibition of Tn554 transposition: Deletion analysis
1983
Site-specific recombination between plasmids of Staphylococcus aureus
1980
Characterizing the Effect of theStaphylococcus aureusVirulence Factor Regulator, SarA, on Log-Phase mRNA Half-Lives
2006
A catenated intermediate in plasmid replication
1973
Transposon Tn554 encodes three products required for transposition.
1988
rpt-1, an intracellular protein from helper/inducer T cells that regulates gene expression of interleukin 2 receptor and human immunodeficiency virus type 1.
1988
Penicillinase plasmids of Staphylococcus aureus: Structural and evolutionary relationships
1980
B7 and interleukin 12 cooperate for proliferation and interferon gamma production by mouse T helper clones that are unresponsive to B7 costimulation.
1994
Global Regulation of Staphylococcus aureus Genes by Rot
2003
Tn554: Isolation and characterization of plasmid insertions
1981
Transposon Tn554: complete nucleotide sequence and isolation of transposition-defective and antibiotic-sensitive mutants.
1985
Circular DNA of human immunodeficiency virus: analysis of circle junction nucleotide sequences
1991
Physical mapping of Staphylococcus aureus penicillinase plasmid pI524: Characterization of an invertible region
1979
Heterogeneity of intracellular cytokine synthesis at the single-cell level in polarized T helper 1 and T helper 2 populations.
1995