Citation Impact
Citing Papers
TFEB Links Autophagy to Lysosomal Biogenesis
2011 StandoutScience
Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
2010 StandoutScience
Impairment of starvation-induced and constitutive autophagy in Atg7 -deficient mice
2005 StandoutNobel
Breast and Ovarian Cancer Risks Due to Inherited Mutations in BRCA1 and BRCA2
2003 StandoutScience
PARP inhibitors: Synthetic lethality in the clinic
2017 StandoutScience
TOR Signaling in Growth and Metabolism
2006 Standout
Triple-Negative Breast Cancer
2010 Standout
Gene expression profiling predicts clinical outcome of breast cancer
2002 StandoutNature
Identification of a RING protein that can interact in vivo with the BRCA1 gene product
1996
Detection of heterozygous mutations in BRCA1 using high density oligonucleotide arrays and two–colour fluorescence analysis
1996
Association of BRCA1 with Rad51 in Mitotic and Meiotic Cells
1997
Cancer Risk Estimates for BRCA1 Mutation Carriers Identified in a Risk Evaluation Program
2002
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
2003 StandoutNobel
A Drosophila Neurexin Is Required for Septate Junction and Blood-Nerve Barrier Formation and Function
1996
AKT/PKB Signaling: Navigating Downstream
2007 Standout
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Mutational Spectra of PTEN/MMAC1 Gene: a Tumor Suppressor With Lipid Phosphatase Activity
1999
Polycomb group protein complexes: do different complexes regulate distinct target genes?
1999
Akt-regulated pathways in prostate cancer
2005
Growth retardation and tumour inhibition by BRCA1
1996
Promoter Hypermethylation and BRCA1 Inactivation in Sporadic Breast and Ovarian Tumors
2000
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas
2004 StandoutNobel
Frontotemporal Dementia and Parkinsonism Linked to Chromosome 17: A New Group of Tauopathies
1998
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
2005 StandoutNature
Ezh1 and Ezh2 Maintain Repressive Chromatin through Different Mechanisms
2008
From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair
1997
The Breast Cancer Susceptibility Gene BRCA1 Is Required for Subnuclear Assembly of Rad51 and Survival following Treatment with the DNA Cross-linking Agent Cisplatin
2000
The multifaceted role of periostin in tumorigenesis
2009
Activation of a Cryptic Splice Site of PTEN and Loss of Heterozygosity in Benign Skin Lesions in Cowden Disease
2001
Cell Death
2004 Standout
PTEN: One Gene, Many Syndromes
2003
Loss of Expression of the PTEN Gene Protein Product Is Associated with Poor Outcome in Breast Cancer
2001
ESDN, a Novel Neuropilin-like Membrane Protein Cloned from Vascular Cells with the Longest Secretory Signal Sequence among Eukaryotes, Is Up-regulated after Vascular Injury
2001 StandoutNobel
Decoding ALS: from genes to mechanism
2016 StandoutNature
Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis
2001
Specific interaction between the XNP/ATR-X gene product and the SET domain of the human EZH2 protein
1998
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
Cloning and Genomic Organization of Beclin 1, a Candidate Tumor Suppressor Gene on Chromosome 17q21
1999
Integrated genomic characterization of endometrial carcinoma
2013 StandoutNature
Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN
1998 StandoutNobel
Identification of a novel contactin-associated transmembrane receptor with multiple domains implicated in protein-protein interactions
1997
Induction of autophagy and inhibition of tumorigenesis by beclin 1
1999 StandoutNature
Autophagy in the Pathogenesis of Disease
2008 Standout
Structure of the Novel C-terminal Domain of Vacuolar Protein Sorting 30/Autophagy-related Protein 6 and Its Specific Role in Autophagy
2012 StandoutNobel
Human Papillomavirus and Survival of Patients with Oropharyngeal Cancer
2010 Standout
The polycomb group protein EZH2 is involved in progression of prostate cancer
2002 StandoutNature
Direct Role for the Replication Protein Treslin (Ticrr) in the ATR Kinase-mediated Checkpoint Response
2013 StandoutNobel
Genetic alterations in breast cancer
1995
Induction of p16 during immortalization by HPV 16 and 18 and not during malignant transformation
1997
Hereditary Colorectal Cancer
2003 Standout
Mutations of the human PTEN gene
2000
PTEN Deletion and Concomitant c-Myc Activation Do Not Lead to Tumor Formation in Pancreatic β Cells
2008 StandoutNobel
Cdc7-Dbf4 and the Human S Checkpoint Response to UVC
2007 StandoutNobel
WHSC1, a 90 kb SET Domain-Containing Gene, Expressed in Early Development and Homologous to a Drosophila Dysmorphy Gene Maps in the Wolf-Hirschhorn Syndrome Critical Region and is Fused to IgH in t(1;14) Multiple Myeloma
1998
PTEN/MMAC1 mutations in hepatocellular carcinomas
1999
Frequency and Carrier Risk Associated with Common BRCA1 and BRCA2 Mutations in Ashkenazi Jewish Breast Cancer Patients
1998
Mammalian homologues of the Polycomb-group gene Enhancer of zeste mediate gene silencing in Drosophila heterochromatin and at S.cerevisiae telomeres
1997
Regulation of chromatin structure by site-specific histone H3 methyltransferases
2000 StandoutNature
BRCT Domain-containing Protein TopBP1 Functions in DNA Replication and Damage Response
2001
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Functional Demarcation of Active and Silent Chromatin Domains in Human HOX Loci by Noncoding RNAs
2007 Standout
The Hallmarks of Aging
2013 Standout
Environmental and Heritable Factors in the Causation of Cancer — Analyses of Cohorts of Twins from Sweden, Denmark, and Finland
2000 Standout
Binding Properties of Neuroligin 1 and Neurexin 1β Reveal Function as Heterophilic Cell Adhesion Molecules
1997 StandoutNobel
The Polycomb complex PRC2 and its mark in life
2011 StandoutNature
In Swedish Families with Hereditary Prostate Cancer, Linkage to the HPC1 Locus on Chromosome 1q24-25 Is Restricted to Families with Early-Onset Prostate Cancer
1999
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
1997 Standout
A trithorax-group complex purified from Saccharomyces cerevisiae is required for methylation of histone H3
2001 StandoutNobel
Selective Colorimetric Detection of Polynucleotides Based on the Distance-Dependent Optical Properties of Gold Nanoparticles
1997 StandoutScience
Founder BRCA1 and BRCA2 mutations in Ashkenazi Jews in Israel: frequency and differential penetrance in ovarian cancer and in breast-ovarian cancer families.
1997
The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics
2002 StandoutScience
Role of Autophagy in Breast Cancer
2007
Membrane proteomics of phagosomes suggests a connection to autophagy
2008 StandoutNobel
Protection against Fatal Sindbis Virus Encephalitis by Beclin, a Novel Bcl-2-Interacting Protein
1998
“The Race” to Clone BRCA1
2014 Science
The Biology and Clinical Relevance of the PTEN Tumor Suppressor Pathway
2004
Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain
1997
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
2018 StandoutNobel
Candidate autism gene screen identifies critical role for cell-adhesion molecule CASPR2 in dendritic arborization and spine development
2012 StandoutNobel
PTEN mutations and microsatellite instability in complex atypical hyperplasia, a precursor lesion to uterine endometrioid carcinoma.
1998
Interaction of Mouse Polycomb-Group (Pc-G) Proteins Enx1 and Enx2 with Eed: Indication for Separate Pc-G Complexes
1998
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
Autophagy as a Regulated Pathway of Cellular Degradation
2000 StandoutScience
Point Mutations in the WD40 Domain of Eed Block Its Interaction with Ezh2
1998
Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten
2004 StandoutNobel
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
Autophagy in Health and Disease: A Double-Edged Sword
2004 StandoutScience
Works of Elizabeth Ostermeyer being referenced
Inherited Mutations in PTEN That Are Associated with Breast Cancer, Cowden Disease, and Juvenile Polyposis
1997
Characterization ofEZH1,a Human Homolog ofDrosophila Enhancer of zestenearBRCA1
1996
Confirmation of BRCA1 by analysis of germline mutations linked to breast and ovarian cancer in ten families
1994
22 genes from chromosome 17q21: cloning, sequencing, and characterization of mutations in breast cancer families and tumors
1995
Novel inherited mutations and variable expressivity of BRCA1 alleles, including the founder mutation 185delAG in Ashkenazi Jewish families.
1995
Founding BRCA1 mutations in hereditary breast and ovarian cancer in southern Sweden.
1996
The search for BRCA1.
1994