Citation Impact
Citing Papers
Crystal Structure of a Mammalian Voltage-Dependent Shaker Family K + Channel
2005 StandoutScienceNobel
Breast and Ovarian Cancer Risks Due to Inherited Mutations in BRCA1 and BRCA2
2003 StandoutScience
Crystal Structure of Rhodopsin: A G Protein-Coupled Receptor
2000 StandoutScience
Mutant G-protein-coupled receptors as a cause of human diseases
2004
Computation and Functional Studies Provide a Model for the Structure of the Zinc Transporter hZIP4
2015 StandoutNobel
Rhodopsin and Phototransduction
1993
The open pore conformation of potassium channels
2002 StandoutNatureNobel
Structure of a mammalian ryanodine receptor
2014 StandoutNatureNobel
Mechanisms of (local) anaesthetics on voltage-gated sodium and other ion channels
2002
Structure of the TRPA1 ion channel suggests regulatory mechanisms
2015 StandoutNatureNobel
The Influence of Chromosomal Location on the Expression of Two Transgenes in Mice
1999 StandoutNobel
Cloning of a retinally abundant regulator of G-protein signaling (RGS-r/RGS16): genomic structure and chromosomal localization of the human gene
1998
Voltage-Gated Sodium Channels: Mutations, Channelopathies and Targets
2011
The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases
1993 StandoutNature
NaV1.1 channels and epilepsy
2010
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain
2016 StandoutNatureNobel
The crystal structure of a voltage-gated sodium channel
2011 Nature
Confronting Complexity: the Interlink of Phototransduction and Retinoid Metabolism in the Vertebrate Retina
2001
Rhodopsin: structure, function, and genetics
1992
Molecular Diversity and Specializations among the Cells of the Adult Mouse Brain
2018
Photonic structures in biology
2003 StandoutNature
Transgenic mice with a rhodopsin mutation (Pro23His): A mouse model of autosomal dominant retinitis pigmentosa
1992
Resting-State Structure and Gating Mechanism of a Voltage-Gated Sodium Channel
2019
A Bivalent Tarantula Toxin Activates the Capsaicin Receptor, TRPV1, by Targeting the Outer Pore Domain
2010 StandoutNobel
Degeneration of skeletal muscle, peripheral nerves, and the central nervous system in transgenic mice overexpressing wild-type prion proteins
1994 StandoutNobel
Recessive mutations in the gene encoding the β–subunit of rod phosphodiesterase in patients with retinitis pigmentosa
1993
Evidence That the Penetrance of Mutations at the RP11 Locus Causing Dominant Retinitis Pigmentosa Is Influenced by a Gene Linked to the Homologous RP11 Allele
1997
A linkage map of mouse Chromosome 1 using an interspecific cross segregating for the gld autoimmunity mutation
1992
Insertional mutation of ‘classical’ and novel genes in transgenic mice
1992
Ion Channel Voltage Sensors: Structure, Function, and Pathophysiology
2010
The Rise and Fall of the Chemoattractant Receptor GPR33
2005 StandoutNobel
G Protein-coupled Receptors
1998 StandoutNobel
Potassium channel receptor site for the inactivation gate and quaternary amine inhibitors
2001 Nature
Evidence for nonallelic genetic heterogeneity in autosomal recessive retinitis pigmentosa
1992
Structure and function of voltage‐gated sodium channels at atomic resolution
2013
A Transient Receptor Potential Vanilloid 4-Dependent Mechanism of Hyperalgesia Is Engaged by Concerted Action of Inflammatory Mediators
2006
TRPV1 structures in distinct conformations reveal activation mechanisms
2013 StandoutNatureNobel
A Membrane-proximal Basic Domain and Cysteine Cluster in the C-terminal Tail of CCR5 Constitute a Bipartite Motif Critical for Cell Surface Expression
2001 StandoutNobel
Structure of the TRPV1 ion channel determined by electron cryo-microscopy
2013 StandoutNatureNobel
Calmodulin Suppresses Synaptotagmin-2 Transcription in Cortical Neurons*
2010 StandoutNobel
Constitutively active mutants of rhodopsin
1992
Structural snapshots of TRPV1 reveal mechanism of polymodal functionality
2021 StandoutNobel
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
Mechanisms of voltage-gated ion channel regulation: from gene expression to localization
2008
The Fas Death Factor
1995 StandoutScience
Cystic fibrosis: molecular biology and therapeutic implications
1992 StandoutScience
Voltage-dependent calcium channels: From structure to function
2005
Rhodopsin mutation G90D and a molecular mechanism for congenital night blindness
1994 Nature
Reduced Cell Surface Expression of CCR5 in CCR5Δ32 Heterozygotes Is Mediated by Gene Dosage, Rather Than by Receptor Sequestration
2002 StandoutNobel
Supramolecular Assemblies and Localized Regulation of Voltage-Gated Ion Channels
2009
Retinopathy induced in mice by targeted disruption of the rhodopsin gene
1997 StandoutNobel
Voltage-gated sodium channels as primary targets of diverse lipid-soluble neurotoxins
2002
Comprehensive Integration of Single-Cell Data
2019 Standout
Crystal structure of an orthologue of the NaChBac voltage-gated sodium channel
2012 Nature
A point mutation of the rhodopsin gene in one form of retinitis pigmentosa
1990 StandoutNature
GTPase Activating Specificity of RGS12 and Binding Specificity of an Alternatively Spliced PDZ (PSD-95/Dlg/ZO-1) Domain
1998 StandoutNobel
Tryptophan Scanning of D1S6 and D4S6 C-Termini in Voltage-Gated Sodium Channels
2003
Nociceptors: the sensors of the pain pathway
2010 StandoutNobel
Apoptosis: Final common pathway of photoreceptor death in rd, rds, and mutant mice
1993
Transmembrane Regions V and VI of the Human Luteinizing Hormone Receptor Are Required for Constitutive Activation by a Mutation in the Third Intracellular Loop
1996 StandoutNobel
α-Neurexins couple Ca2+ channels to synaptic vesicle exocytosis
2003 StandoutNatureNobel
Structural Instability of a Constitutively Active G Protein-coupled Receptor
1997 StandoutNobel
Tracking a complete voltage-sensor cycle with metal-ion bridges
2012
The Role of Voltage-Gated Calcium Channels in Pancreatic β-Cell Physiology and Pathophysiology
2006
Structure and Regulation of Voltage-Gated Ca2+ Channels
2000 Standout
Digenic Retinitis Pigmentosa Due to Mutations at the Unlinked Peripherin/ RDS and ROM1 Loci
1994 Science
A rhodopsin gene mutation responsible for autosomal dominant retinitis pigmentosa results in a protein that is defective in localization to the photoreceptor outer segment
1994
Apoptosis in the Pathogenesis and Treatment of Disease
1995 StandoutScience
PKD2 , a Gene for Polycystic Kidney Disease That Encodes an Integral Membrane Protein
1996 StandoutScience
The hitchhiker’s guide to the voltage-gated sodium channel galaxy
2015
Gating charge interactions with the S1 segment during activation of a Na + channel voltage sensor
2011
Functional redundancy of cryptochromes and classical photoreceptors for nonvisual ocular photoreception in mice
2000 StandoutNobel
Prokaryotic NavMs channel as a structural and functional model for eukaryotic sodium channel antagonism
2014
The Caenorhabditis elegans mucolipin-like gene cup-5 is essential for viability and regulates lysosomes in multiple cell types
2002 StandoutNobel
Positional cloning: Let's not call it reverse anymore
1992
Odorant-selective genes and neurons mediate olfaction in C. elegans
1993 StandoutNobel
Inositol hexakisphosphate suppresses excitatory neurotransmission via synaptotagmin-1 C2B domain in the hippocampal neuron
2012 StandoutNobel
Mutations in the gene encoding the alpha subunit of the rod cGMP-gated channel in autosomal recessive retinitis pigmentosa.
1995
Genetic Dissection of Complex Traits
1994 StandoutScience
Molecular Genetics of Human Retinal Disease
1999
Pharmacology of the Na v 1.1 domain IV voltage sensor reveals coupling between inactivation gating processes
2017 StandoutNobel
GROMACS: High performance molecular simulations through multi-level parallelism from laptops to supercomputers
2015 Standout
Emerging Targets in Photopharmacology
2016 StandoutNobel
Ligand-induced overexpression of a constitutively active β 2 -adrenergic receptor: Pharmacological creation of a phenotype in transgenic mice
1997 StandoutNobel
On the Molecular Genetics of Retinitis Pigmentosa
1992 Science
Structural insights into TRPM8 inhibition and desensitization
2019 StandoutScienceNobel
Hypermorphic mutation of the voltage-gated sodium channel encoding gene Scn10a causes a dramatic stimulus-dependent neurobehavioral phenotype
2011 StandoutNobel
Structure and mechanism of the G protein-coupled receptor kinases.
1993 StandoutNobel
Structural basis for gating charge movement in the voltage sensor of a sodium channel
2011 StandoutNobel
Works of Elizabeth M. Sharp being referenced
A three-base-pair deletion in the peripherin–RDS gene in one form of retinitis pigmentosa
1991 Nature
Functional properties and differential neuromodulation of Nav1.6 channels
2008
Autosomal dominant retinitis pigmentosa (ADRP): Localization of an ADRP gene to the long arm of chromosome 3
1989
Autosomal dominant retinitis pigmentosa: Localization of a disease gene (RP6) to the short arm of chromosome 6
1991
Molecular Determinants of Voltage-dependent Gating and Binding of Pore-blocking Drugs in Transmembrane Segment IIIS6 of the Na+ Channel α Subunit
2001
Epidermolysis bullosa: Evidence for linkage to genetic markers on chromosome 1 in a family with the autosomal dominant simplex form
1990
Fine mapping of the autosomal recessive retinitis pigmentosa locus (RP12) on chromosome 1q; exclusion of the phosducin gene (PDC)
1996
Autosomal dominant retinitis pigmentosa: Linkage to rhodopsin and evidence for genetic heterogeneity
1990
Molecular Mechanism of Convergent Regulation of Brain Na+ Channels by Protein Kinase C and Protein Kinase A Anchored to AKAP-15
2002
Autosomal dominant retinitis pigmentosa (adRP; RP6): cosegregation of RP6 and the peripherin-RDS locus in a late-onset family of Irish origin.
1992
Inhibition of cardiac L-type calcium channels by protein kinase C phosphorylation of two sites in the N-terminal domain
2000
Sequential formation of ion pairs during activation of a sodium channel voltage sensor
2009
Autosomal dominant retinitis pigmentosa: A mutation in codon 178 of the rhodopsin gene in two families of celtic origin
1991
Autosomal dominant retinitis pigmentosa: absence of the rhodopsin proline->histidine substitution (codon 23) in pedigrees from Europe
1990
Construction of a high-affinity receptor site for dihydropyridine agonists and antagonists by single amino acid substitutions in a non- l -type Ca 2+ channel
1997