Citation Impact
Citing Papers
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Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions
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Regulation of alternative splicing by a transcriptional enhancer through RNA pol II elongation
2002 StandoutNobel
ATAC is a double histone acetyltransferase complex that stimulates nucleosome sliding
2008
A Steroid Receptor Coactivator, SRA, Functions as an RNA and Is Present in an SRC-1 Complex
1999
Cloning, expression, and transcriptional properties of the human enhancer factor TEF-1
1991
Estrogen receptor mutations in breast cancer
1993
Influence of Metabolism on Epigenetics and Disease
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A comparison of transcriptional activation by ERα and ERβ
1999
Differential Interaction of Nuclear Receptors with the Putative Human Transcriptional Coactivator hTIF1
1997
Transcription Activation by the Human Estrogen Receptor Subtypeβ (ERβ) Studied with ERβ and ERα Receptor Chimeras1
1998
Chromatin Modifications and Their Function
2007 Standout
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2010
Systematic analysis of essential yeast TAFs in genome-wide transcription and preinitiation complex assembly
2003
The coactivator TIF2 contains three nuclear receptor-binding motifs and mediates transactivation through CBP binding-dependent and -independent pathways
1998
extradenticle, a regulator of homeotic gene activity, is a homolog of the homeobox-containing human proto-oncogene pbx1
1993 StandoutNobel
Activation of an inducible c-FosER fusion protein causes loss of epithelial polarity and triggers epithelial-fibroblastoid cell conversion
1992
Switching of the core transcription machinery during myogenesis
2007
Molecular cloning and characterization of human estrogen receptor betacx: a potential inhibitor ofestrogen action in human
1998
RSC, an Essential, Abundant Chromatin-Remodeling Complex
1996 StandoutNobel
Shifting Players and Paradigms in Cell-Specific Transcription
2009
Promoter specificity of the two transcriptional activation functions of the human oestrogen receptor in yeast
1992
The Mediator complex: a central integrator of transcription
2015
A Mutant Drosophila Homolog of Mammalian Clock Disrupts Circadian Rhythms and Transcription of period and timeless
1998 StandoutNobel
Quantifying transcription factor kinetics: At work or at play?
2013
A signature motif in transcriptional co-activators mediates binding to nuclear receptors
1997 StandoutNature
Modulation of mouse estrogen receptor transcription activity by protein kinase C delta
1998
The mechanism of RU486 antagonism is dependent on the conformation of the carboxy-terminal tail of the human progesterone receptor
1992
Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours
1996 StandoutNature
A novel cis element mediating ligand-independent activation by c-ErbA: Implications for hormonal regulation
1993
Phosphorylation of the human estrogen receptor by mitogen-activated protein kinase and casein kinase II: Consequence on DNA binding
1995
TRIBE: Hijacking an RNA-Editing Enzyme to Identify Cell-Specific Targets of RNA-Binding Proteins
2016 StandoutNobel
Non-heme dioxygenases: cellular sensors and regulators jelly rolled into one?
2007
Single-Molecule Dynamics of Enhanceosome Assembly in Embryonic Stem Cells
2014 StandoutNobel
Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
1990 StandoutNature
p300 and estrogen receptor cooperatively activate transcription via differential enhancement of initiation and reinitiation
1998
The complex language of chromatin regulation during transcription
2007 StandoutNature
A Novel Proteolytic Cleavage Involved in Notch Signaling
2000 Standout
Role of Protein Methylation in Regulation of Transcription
2005
A far upstream estrogen response element of the ovalbumin gene contains several half-palindromic 5′-TGACC-3′ motifs acting synergistically
1992
Different Regions in Activation Function-1 of the Human Estrogen Receptor Required for Antiestrogen- and Estradiol-dependent Transcription Activation
1996
Histone H3 Lys 4 methylation: caught in a bind?
2006
The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation
2008
Interaction of Steroid Hormone Receptors with the Transcription Initiation Complex
1996
Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
2007 StandoutNature
Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
2020 Standout
The p53 tumour suppressor gene
1991 StandoutNature
Epidermal barrier formation and recovery in skin disorders
2006
The Drosophila gene tailless is expressed at the embryonic termini and is a member of the steroid receptor superfamily
1990 StandoutNobel
Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-α
1995 Nature
The polycomb group protein EZH2 is involved in progression of prostate cancer
2002 StandoutNature
The unc-86 gene product couples cell lineage and cell identity in C. elegans
1990 StandoutNobel
Specific modulation of estrogen receptor mRNA isoforms in rat pituitary throughout the estrous cycle and in response to steroid hormones
1997
Dynamic Lysine Methylation on Histone H3 Defines the Regulatory Phase of Gene Transcription
2005
Interaction between the Amino- and Carboxyl-terminal Regions of the Rat Androgen Receptor Modulates Transcriptional Activity and Is Influenced by Nuclear Receptor Coactivators
1997
Neurotransmitters activate the human estrogen receptor in a neuroblastoma cell line
1997
Multiplicity generates diversity in the retinoic acid signalling pathways
1992
A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins
1995
The yeast Ada complex mediates the ligand-dependent activation function AF-2 of retinoid X and estrogen receptors
1998
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
Roles of TFIID in transcriptional initiation by RNA polymerase II
1991
Molecular cloning and characterization of Japanese eel estrogen receptor cDNA
1996
Molecular basis of agonism and antagonism in the oestrogen receptor
1997 StandoutNature
The interactions of transcription factors and their adaptors, coactivators and accessory proteins
1991
Two Separate Mechanisms for Ligand-Independent Activation of the Estrogen Receptor
1997
The Putative Cofactor TIF1α Is a Protein Kinase That Is Hyperphosphorylated upon Interaction with Liganded Nuclear Receptors
1998
In vivo and in vitro phosphorylation of the human estrogen receptor
1995
Subnuclear segregation of genes and core promoter factors in myogenesis
2011 StandoutNobel
Identification of phosphorylation sites in the mouse oestrogen receptor
1995
Human TAFII30 is present in a distinct TFIID complex and is required for transcriptional activation by the estrogen receptor
1994
Two distinct nuclear receptor interaction domains in NSD1, a novel SET protein that exhibits characteristics of both corepressors and coactivators
1998
Thyroid Hormone Receptors Form Distinct Nuclear Protein-Dependent and Independent Complexes with a Thyroid Hormone Response Element
1990
Developmental regulation of transcription initiation: more than just changing the actors
2010
Human TAF(II)135 potentiates transcriptional activation by the AF-2s of the retinoic acid, vitamin D3, and thyroid hormone receptors in mammalian cells.
1997
The Mechanism of ICI 164,384 Antiestrogenieity Involves Rapid Loss of Estrogen Receptor in Uterine Tissue
1991
Regulation of transcription and cell identity by POU domain proteins
1991 StandoutNobel
Characterization of the Amino-terminal Transcriptional Activation Function of the Human Estrogen Receptor in Animal and Yeast Cells
1995
The POU-specific domain of Pit-1 is essential for sequence-specific, high affinity DNA binding and DNA-dependent Pit-1—Pit-1 interactions
1990
Sexual Dimorphism in Innate Immunity
2017
Determinants for the repression of estrogen receptor transcriptional activity by ligand-occupied progestin receptors
1997
Promoter context- and response element-dependent specificity of the transcriptional activation and modulating functions of retinoic acid receptors
1992
Estrogen Receptor Activation Function 1 Works by Binding p160 Coactivator Proteins
1998
Gene regulation by steroid hormones
1989 Standout
Basal and Thyroid Hormone Receptor Auxiliary Protein- Enhanced Binding of Thyroid Hormone Receptor Isoforms to Native Thyroid Hormone Response Elements
1991
The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
2008 Standout
A conserved retinoic acid response element required for early expression of the homeobox gene Hoxb-1
1994 StandoutNatureNobel
STAGA Recruits Mediator to the MYC Oncoprotein To Stimulate Transcription and Cell Proliferation
2007
Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene.
1993 StandoutNobel
Notch receptor cleavage depends on but is not directly executed by presenilins
2002 StandoutNobel
Conversion of the lac repressor into an allosterically regulated transcriptional activator for mammalian cells.
1990
Cell-Specific Inhibition of Retinoic Acid Receptor-α Silencing by the AF2/τc Activation Domain Can Be Overcome by the Corepressor SMRT, But Not by N-CoR
1998
Ligand-dependent, transcriptionally productive association of the amino- and carboxyl-terminal regions of a steroid hormone nuclear receptor.
1995
Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B.
1990
RIP-140 Interacts with Multiple Nuclear Receptors by Means of Two Distinct Sites
1996
Identification and characterization of a TFIID-like multiprotein complex from Saccharomyces cerevisiae.
1995 StandoutNobel
Ligand-dependent interactions of coactivators steroid receptor coactivator-1 and peroxisome proliferator-activated receptor binding protein with nuclear hormone receptors can be imaged in live cells and are required for transcription
2000 StandoutNobel
Serine 167 is the major estradiol-induced phosphorylation site on the human estrogen receptor.
1994
Inhibition of estrogen-responsive gene activation by the retinoid X receptor beta: evidence for multiple inhibitory pathways.
1993
Differential ligand-dependent interactions between the AF-2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1.
1996
Coactivator and Corepressor Regulation of the Agonist/Antagonist Activity of the Mixed Antiestrogen, 4-Hydroxytamoxifen
1997
Yeast Taf170 is encoded by MOT1 and exists in a TATA box-binding protein (TBP)-TBP-associated factor complex distinct from transcription factor IID.
1994
Modulation of the ligand-independent activation of the human estrogen receptor by hormone and antihormone.
1993
Transcriptional regulation of Notch and Delta: requirement for neuroblast segregation in Drosophila
1997
Mechanisms for synergistic activation of thyroid hormone receptor and retinoid X receptor on different response elements.
1994
Immunosuppression by Glucocorticoids: Inhibition of NF-κB Activity Through Induction of IκB Synthesis
1995 StandoutScience
DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells
2000 StandoutNobel
Ligand-dependent Cross-talk between Steroid and Thyroid Hormone Receptors
1996
TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors.
1996
Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor.
1995
Abnormal Vascular Function and Hypertension in Mice Deficient in Estrogen Receptor β
2002 StandoutScienceNobel
Down-modulation of interleukin-6 gene expression by 17 beta-estradiol in the absence of high affinity DNA binding by the estrogen receptor.
1994
The Thyroid Hormone Receptor-Associated Protein TRAP220 Is Required at Distinct Embryonic Stages in Placental, Cardiac, and Hepatic Development
2003
The Estrogen Receptor Enhances AP-1 Activity by Two Distinct Mechanisms with Different Requirements for Receptor Transactivation Functions
1999
Physiological coupling of growth factor and steroid receptor signaling pathways: estrogen receptor knockout mice lack estrogen-like response to epidermal growth factor.
1996
GRIP1, a novel mouse protein that serves as a transcriptional coactivator in yeast for the hormone binding domains of steroid receptors.
1996
Holo-TFIID controls the magnitude of a transcription burst and fine-tuning of transcription
2013
Physiological and Molecular Basis of Thyroid Hormone Action
2001 Standout
The TFIID Components Human TAFII140 andDrosophila BIP2 (TAFII155) Are Novel Metazoan Homologues of Yeast TAFII47 Containing a Histone Fold and a PHD Finger
2001
RAC3, a steroid/nuclear receptor-associated coactivator that is related to SRC-1 and TIF2
1997
Mechanisms of Estrogen Action
2001 Standout
Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members
2001 StandoutNobel
Phosphorylation of the human estrogen receptor. Identification of hormone-regulated sites and examination of their influence on transcriptional activity.
1994
Human nuclear receptor heterodimers: opportunities for detecting targets of transcriptional regulation using yeast.
1996
Analysis of estrogen receptor transcriptional enhancement by a nuclear hormone receptor coactivator.
1996
Histone Acetyltransferase Complexes Can Mediate Transcriptional Activation by the Major Glucocorticoid Receptor Activation Domain
1999
Estrogen Receptor-Associated Proteins: Possible Mediators of Hormone-Induced Transcription
1994 Science
The Molecular Pharmacology of SERMs
1999
The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18.
1995
Molecular Determinants of the Estrogen Receptor-Coactivator Interface
1999
Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors.
1992
Role of the two activating domains of the oestrogen receptor in the cell-type and promoter-context dependent agonistic activity of the anti-oestrogen 4-hydroxytamoxifen.
1990
Repression of the Interleukin-6 Promoter by Estrogen Receptor Is Mediated by NF-κB and C/EBPβ
1995
AF-2 Activity and Recruitment of Steroid Receptor Coactivator 1 to the Estrogen Receptor Depend on a Lysine Residue Conserved in Nuclear Receptors
1997
Cloning and characterization of hTAFII18, hTAFII20 and hTAFII28: three subunits of the human transcription factor TFIID.
1995
The putative nuclear receptor mediator TIF1α is tightly associated with euchromatin
1999
Nuclear Receptor Coregulators: Cellular and Molecular Biology*
1999 Standout
Identification of charged residues in an N-terminal portion of the hormone-binding domain of the human estrogen receptor important in transcriptional activity of the receptor.
1993
Definition of a novel ligand binding domain of a nuclear bHLH receptor: co-localization of ligand and hsp90 binding activities within the regulable inactivation domain of the dioxin receptor.
1993
Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins
1989 StandoutScience
Characterization of the ligand-dependent transactivation domain of thyroid hormone receptor.
1994
Members of the steroid hormone receptor superfamily interact with TFIIB (S300-II).
1992
Coactivator TIF1β Interacts with Transcription Factor C/EBPβ and Glucocorticoid Receptor To Induce α1-Acid Glycoprotein Gene Expression
1998
Human TAF(II28) promotes transcriptional stimulation by activation function 2 of the retinoid X receptors.
1996
A 10-Amino-Acid Sequence in the N-Terminal A/B Domain of Thyroid Hormone Receptor α Is Essential for Transcriptional Activation and Interaction with the General Transcription Factor TFIIB
1995
Analysis of estrogen receptor function in vitro reveals three distinct classes of antiestrogens.
1995
Steroid receptor induction of gene transcription: A two-step model
1997
Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth
2014 StandoutNobel
Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet
2011 StandoutNobel
Several regions of human estrogen receptor are involved in the formation of receptor-heat shock protein 90 complexes
1990
Yeast RNA polymerase II initiation factor e: isolation and identification as the functional counterpart of human transcription factor IIB.
1992 StandoutNobel
Notch Signaling: Cell Fate Control and Signal Integration in Development
1999 StandoutScience
Cooperative Interactions Between the Caenorhabditis elegans Homeoproteins UNC-86 and MEC-3
1993 StandoutScienceNobel
Divergent Pathways Regulate Ligand-Independent Activation of ERα in SK-N-BE Neuroblastoma and COS-1 Renal Carcinoma Cells
1998
Sequence and Characterization of a Coactivator for the Steroid Hormone Receptor Superfamily
1995 StandoutScience
Evidence for a factor required for transcriptional stimulation by the chimeric acidic activator GAL-VP16 in HeLa cell extracts.
1991
Conversion of the lac Repressor into an Allosterically Regulated Transcriptional Activator for Mammalian Cells
1990
Interaction of proteins with transcriptionally active estrogen receptors.
1994
Transcriptional Activators Differ in Their Responses to Overexpression of TATA-Box-Binding Protein
1995
A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor.
1993
Yeast RSP5 and Its Human Homolog hRPF1 Potentiate Hormone-Dependent Activation of Transcription by Human Progesterone and Glucocorticoid Receptors
1996
Modulation of transcriptional activation by ligand-dependent phosphorylation of the human oestrogen receptor A/B region.
1993
The t4 Activation Domain of the Thyroid Hormone Receptor Is Required for Release of a Putative Corepressor(s) Necessary for Transcriptional Silencing
1995
Enhancement of human estrogen receptor activity by SPT6: a potential coactivator.
1995
Phosphorylation of Human Estrogen Receptor α by Protein Kinase A Regulates Dimerization
1999
Activation of the Estrogen Receptor Through Phosphorylation by Mitogen-Activated Protein Kinase
1995 StandoutScience
Selective antagonism of thyroid hormone action by retinoic acid.
1992
Simple derivation of TFIID-dependent RNA polymerase II transcription systems from Schizosaccharomyces pombe and other organisms, and factors required for transcriptional activation.
1992 StandoutNobel
Functional analysis of a transactivation domain in the thyroid hormone beta receptor.
1994
A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors.
1996
Association of the Mediator complex with enhancers of active genes
2003 StandoutNobel
A Nuclear Receptor Corepressor Modulates Transcriptional Activity of Antagonist-Occupied Steroid Hormone Receptor
1998
Works of Elisabeth Scheer being referenced
The architecture of human general transcription factor TFIID core complex
2013 Nature
TAF10 is required for the establishment of skin barrier function in foetal, but not in adult mouse epidermis
2005
The human estrogen receptor has two independent nonacidic transcriptional activation functions
1989
Gene-Specific Modulation of TAF10 Function by SET9-Mediated Methylation
2004
Identification of a Small TAF Complex and Its Role in the Assembly of TAF-Containing Complexes
2007
Different TBP-associated factors are required for mediating the stimulation of transcriptionin vitroby the acidic transactivator GAL-VP16 and the two nonacidic activation functions of the estrogen receptor
1993
Chromatin interaction of TATA-binding protein is dynamically regulated in human cells
2010
Two Different Drosophila ADA2 Homologues Are Present in Distinct GCN5 Histone Acetyltransferase-Containing Complexes
2002
Distinct classes of transcriptional activating domains function by different mechanisms
1990
TAF10 (TAFII30) Is Necessary for TFIID Stability and Early Embryogenesis in Mice
2003
TAF9b (Formerly TAF9L) Is a Bona Fide TAF That Has Unique and Overlapping Roles with TAF9
2005