Standout Papers
- Multiple cutaneous and subcutaneous lesions occurring simultaneously with hereditary polyposis and osteomatosis. (1953)
Citation Impact
Citing Papers
Neurotoxic protein expression reveals connections between the circadian clock and mating behavior in Drosophila
2006 StandoutNobel
β-Catenin regulates expression of cyclin D1 in colon carcinoma cells
1999 StandoutNature
Are different events involved in the development of sporadic versus hereditary tumours? The possible importance of the microenvironment in hereditary cancer
1990
Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells
1992 StandoutNobel
Dominant genes for colorectal cancer are not rare
1992
The secretory phospholipase A2 gene is a candidate for the Mom1 locus, a major modifier of ApcMin-induced intestinal neoplasia
1995
Genetic instabilities in human cancers
1998 StandoutNature
A genetic model for colorectal tumorigenesis
1990 Standout
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties
1992 StandoutNobel
The ground state of embryonic stem cell self-renewal
2008 StandoutNature
Alleles of the APC gene: An attenuated form of familial polyposis
1993
The Hallmarks of Cancer
2000 Standout
Lessons from Hereditary Colorectal Cancer
1996 Standout
Molecular Diagnosis of Familial Adenomatous Polyposis
1993
Tumor suppressor genes
1991 Standout
Polyglutamine-Expanded Human Huntingtin Transgenes Induce Degeneration of Drosophila Photoreceptor Neurons
1998
Mechanisms of carcinogenesis and the mutant mouse
1996
Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kγ
2000 StandoutNatureNobel
The Molecular Basis of Turcot's Syndrome
1995
The p53 tumour suppressor gene
1991 StandoutNature
The ABC of APC
2001
Immunity, Inflammation, and Cancer
2010 Standout
Mutations of theAPC adenomatous polyposis coli) gene
1993
Hereditary Colorectal Cancer
2003 Standout
Hereditary Gastrointestinal Polyposis and Nonpolyposis Syndromes
1994
C. elegans unc-4 gene encodes a homeodomain protein that determines the pattern of synaptic input to specific motor neurons
1992 StandoutNatureNobel
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
1992 StandoutNature
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
Genetics, natural history, tumor spectrum, and pathology of hereditary nonpolyposis colorectal cancer: An updated review
1993
Restriction of ocular fundus lesions to a specific subgroup of APC mutations in adenomatous polyposis coli patients
1993
Genetic mapping of a second locus predisposing to hereditary non–polyposis colon cancer
1993
The Endophenotype Concept in Psychiatry: Etymology and Strategic Intentions
2003 Standout
Mismatch Repair Deficiency in Phenotypically Normal Human Cells
1995 StandoutScienceNobel
Genetic Alterations during Colorectal-Tumor Development
1988 Standout
The Putative Tumor Suppressors EXT1 and EXT2 Are Glycosyltransferases Required for the Biosynthesis of Heparan Sulfate
1998
Wnt signalling in stem cells and cancer
2005 StandoutNature
Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse
1993
Cyclin A and the retinoblastoma gene product complex with a common transcription factor
1991 StandoutNatureNobel
Hypermutability and mismatch repair deficiency in RER+ tumor cells
1993 StandoutNobel
Evolution of hereditary non-polyposis colorectal cancer.
1992
Allelic Loss in Colorectal Carcinoma
1989
Loss of constitutional heterozygosity in colorectal tumors from patients with familial polyposis coli and those with nonpolyposis colorectal carcinoma.
1989
p53 Mutations in Human Cancers
1991 StandoutScience
Genetics and cancer
1980
The human T-cell receptor α-chain gene maps to chromosome 14
1985 StandoutNatureNobel
Severe Gardner syndrome in families with mutations restricted to a specific region of the APC gene.
1995
Temperature-Sensitive Mutations in Drosophila melanogaster
1970 Science
SQV-7, a protein involved in Caenorhabditis elegans epithelial invagination and early embryogenesis, transports UDP-glucuronic acid, UDP- N - acetylgalactosamine, and UDP-galactose
2001 StandoutNobel
A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
2006 StandoutNature
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Inherited Susceptibility to Colorectal Cancer
2005
Concerted Nonsyntenic Allelic Loss in Human Colorectal Carcinoma
1988 Science
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
Conservation of synteny between the genome of the pufferfish (Fugu rubripes) and the region on human chromosome 14 (14q24.3) associated with familial Alzheimer disease (AD3 locus)
1996 StandoutNobel
HUMAN TUMOR SUPPRESSOR GENES
1990
β-Arrestin1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteins
2001 StandoutNobel
Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC −/− Colon Carcinoma
1997 StandoutScience
Influence of Life Stress on Depression: Moderation by a Polymorphism in the 5-HTT Gene
2003 StandoutScience
Identification of the Cystic Fibrosis Gene: Genetic Analysis
1989 StandoutScience
Developmental Genetics of Homoeosis
1976
Hypomethylation of DNA from Benign and Malignant Human Colon Neoplasms
1985 Science
Tumor Rejection After Direct Costimulation of CD8 + T Cells by B7-Transfected Melanoma Cells
1993 StandoutScienceNobel
Cancer Genome Landscapes
2013 StandoutScience
Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA
1989 StandoutScience
Genetic interactions affecting touch sensitivity in Caenorhabditis elegans.
1996 StandoutNobel
The Molecular Genetics of Cancer
1987 StandoutScienceNobel
PTEN , a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer
1997 StandoutScience
A suppressor mutation in the nematode acting on specific alleles of many genes
1978 StandoutNatureNobel
A genetic pathway for the specification of the vulval cell lineages of Caenorhabditis elegans
1987 StandoutNatureNobel
Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC
1997 StandoutScience
Hereditary nonpolyposis colorectal cancer (lynch syndromes I and II). II. Biomarker studies
1985
CpG island clones from a deletion encompassing the gene for adenomatous polyposis coli.
1989
Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs.
1995 StandoutNobel
Biallelic inactivation of hMLH 1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers
1998 StandoutNobel
p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis.
1990
The lin-12 locus specifies cell fates in caenorhabditis elegans
1983 StandoutNobel
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
Mechanisms of Suppression
1973
Gardner syndrome in a man with an interstitial deletion of 5q
1986
Identification and regional localization of DNA markers on chromosome 7 for the cloning of the cystic fibrosis gene.
1988
SIGNALING PATHWAYS IN INTESTINAL DEVELOPMENT AND CANCER
2004
Chromosome 17 Deletions and p53 Gene Mutations in Colorectal Carcinomas
1989 StandoutScience
Allelotype of Colorectal Carcinomas
1989 Science
Multiple Intestinal Neoplasia Caused by a Mutation in the Murine Homolog of the APC Gene
1992 Science
Human c-fos oncogene mapped within chromosomal region 14q21----q31.
1984
Dimer formation by an N-terminal coiled coil in the APC protein.
1993
Expression of ΔNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours
2002
Works of Eldon J. Gardner being referenced
Genetic Analysis of an Inherited Predisposition to Colon Cancer in a Family with a Variable Number of Adenomatous Polyps
1990
GENETICS OF THE EYES-REDUCED MUTANT OF DROSOPHILA MELANOGASTER , WITH SPECIAL REFERENCE TO HOMOEOSIS AND EYELESSNESS
1966
A genetic and clinical study of intestinal polyposis, a predisposing factor for carcinoma of the colon and rectum.
1951
Follow-up study of a family group exhibiting dominant inheritance for a syndrome including intestinal polyps, osteomas, fibromas and epidermal cysts.
1962
Failure to demonstrate a chromosome 2 deletion in adenomatous colorectal polyposis patients
1984
Tumorous Head in Drosophila
1970
Inherited susceptibility to retrovirus-induced transformation of Gardner syndrome cells.
1983
Hereditary multiple exostosis
1987
Spontaneous mesenteric fibromatosis in Gardner's syndrome
1981
The Gene for Familial Polyposis Coli Maps to the Long Arm of Chromosome 5
1987 Science
THE EFFECT OF COPPER AND IRON SALTS AND TRYPTOPHAN ON HEAD ABNORMALITIES AND MELANOTIC TUMORS IN DIFFERENT STOCKS OF DROSOPHILA MELANOGASTER
1960
Upper gastrointestinal polyps in Gardner's syndrome
1984
Hereditary pattern for multiple osteomas in a family group.
1952
Classification and risk assessment of individuals with familial polyposis, Gardner's syndrome, and familial non-polyposis colon cancer from [3H]thymidine labeling patterns in colonic epithelial cells.
1984
Numerical and structural chromosome aberrations in cultured lymphocytes and cutaneous fibroblasts of patients with multiple adenomas of the colorectum
1982
A NEW EYE PHENOTYPE IN DROSOPHILA MELANOGASTER EXPRESSED ONLY AT TEMPERATURES ABOVE 25°C
1962
Multiple cutaneous and subcutaneous lesions occurring simultaneously with hereditary polyposis and osteomatosis.
1953 Standout
MATERNAL EFFECT TRANSFERRED BY INJECTION AND FURTHER ANALYSIS OF TEMPERATURE EFFECTIVE PERIOD FOR TUMOROUS HEAD IN DROSOPHILA MELANOGASTER
1960
The compound eye in the opaque-eye phenotype ofDrosophila melanogaster
1975
Prevalence and Importance of Pigmented Ocular Fundus Lesions in Gardner's Syndrome
1987