Citation Impact
Citing Papers
Multidimensional traction force microscopy reveals out-of-plane rotational moments about focal adhesions
2012 StandoutNobel
Taking Cell-Matrix Adhesions to the Third Dimension
2001 StandoutScience
Actin retrograde flow actively aligns and orients ligand-engaged integrins in focal adhesions
2017 StandoutNobel
Dual-color superresolution imaging of genetically expressed probes within individual adhesion complexes
2007 StandoutNobel
Distinct cellular functions mediated by different VLA integrin α subunit cytoplasmic domains
1992
Integrin-Mediated Signal Transduction in Human Endothelial Cells: Analysis of Tyrosine Phosphorylation Events
1994
Release of Biological Activities from Quiescent Fibronectin by a Conformational Change and Limited Proteolysis by Matrix Metalloproteinases
1995
Distinct populations of basal keratinocytes express stromelysin-1 and stromelysin-2 in chronic wounds.
1994
2011 ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention
2011 Standout
Regulated expression and binding of three VLA (β1) integrin receptors on T cells
1990 Nature
A Mechanism for Regulating Pulmonary Inflammation and Fibrosis: The Integrin αvβ6 Binds and Activates Latent TGF β1
1999 Standout
Characteristics of cerebrovascular accidents after percutaneous coronary interventions
2004
Molecular cloning of the human α6 integrin subunit
1991
Affinity of integrins for damaged extracellular matrix: αvβ3 binds to denatured collagen type I through RGD sites
1992
Adhesion molecules in cancer: the role of integrins
1993
Laminins and other strange proteins
1992
Synaptic transmission: A bidirectional and self-modifiable form of cell-cell communication
1993 StandoutNobel
Focal adhesion kinase is abundant in developing blood vessels and elevation of its phosphotyrosine content in vascular smooth muscle cells is a rapid response to angiotensin II
1994
The Hallmarks of Cancer
2000 Standout
Integrins and cancer
1996
The Oncogenic Cysteine-rich LIM domain protein Rbtn2 is essential for erythroid development
1994 StandoutNobel
Adhesion assembly, disassembly and turnover in migrating cells – over and over and over again
2002
A New Equation to Estimate Glomerular Filtration Rate
2009 Standout
Roles of Adhesion Molecules in T‐Cell Recognition: Fundamental Similarities between Four Integrins on Resting Human T Cells (LFA‐1, VLA‐4, VLA‐5, VLA‐6) in Expression, Binding, and Costimulation
1990
Focal Adhesions: A Nexus for Intracellular Signaling and Cytoskeletal Dynamics
2000
Extracellular Matrix Molecules and their Receptors: Functions in Neural Development
1991
The microenvironment of the tumour–host interface
2001 StandoutNature
Cell adhesion: integrating cytoskeletal dynamics and cellular tension
2010 Standout
A polymeric form of fibronectin has antimetastatic effects against multiple tumor types
1996
Role of the extracellular matrix in the degradation of connective tissue
1994
Integrin cytoplasmic domains: mediators of cytoskeletal linkages and extra- and intracellular initiated transmembrane signaling
1993
Degradation of Fibronectin and Vitronectin and Vitronectin in Chronic Wound Fluid: Analysis by Cell Blotting, Immunoblotting, and Cell Adhesion Assays
1992
Cell Migration: A Physically Integrated Molecular Process
1996 Standout
Adhesion receptors of the immune system
1990 StandoutNature
Switching from differentiation to growth in hepatocytes: Control by extracellular matrix
1992
Comparison of Coronary Drug-Eluting Stents Versus Coronary Artery Bypass Grafting in Patients With Diabetes Mellitus
2007
Changes in keratinocyte adhesion during terminal differentiation: Reduction in fibronectin binding precedes α5β1 integrin loss from the cell surface
1990
Association of chronic kidney disease with clinical outcomes after coronary revascularization: The arterial revascularization therapies study (ARTS)
2005
Sensing the environment: a historical perspective on integrin signal transduction
2002
Molecular Mechanisms of Axon Growth and Guidance
1991
Adhesion in cell migration
1995
Signal transduction by integrin receptors for extracellular matrix: cooperative processing of extracellular information
1992
Regulation of cell movement is mediated by stretch-activated calcium channels
1999 Nature
The Hallmarks of Aging
2013 Standout
A matrix metalloproteinase expressed on the surface of invasive tumour cells
1994 StandoutNature
Cardiovascular Outcomes and All-Cause Mortality: Exploring the Interaction Between CKD and Cardiovascular Disease
2006
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Molecular basis of sun-induced premature skin ageing and retinoid antagonism
1996 StandoutNature
Tales from the crypt[ic] sites of the extracellular matrix
2003
Integrins
2002 Standout
Ligands “activate” integrin αIIbβ3 (platelet GPIIb-IIIa)
1991
Integrins.
1991
Eomesodermin is required for mouse trophoblast development and mesoderm formation
2000 StandoutNatureNobel
Matrix Metalloproteinases
1999 Standout
Integrin alpha 6/beta 4 complex is located in hemidesmosomes, suggesting a major role in epidermal cell-basement membrane adhesion.
1991
Developmental regulation of integrin expression at the time of implantation in the mouse embryo
1993
Altered metabolic and adhesive properties and increased tumorigenesis associated with increased expression of transforming growth factor beta 1.
1992
Physical and biochemical regulation of integrin release during rear detachment of migrating cells
1998
Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice
1995 StandoutNature
Kidney Disease as a Risk Factor for Development of Cardiovascular Disease
2003 Standout
Stimulation of tyrosine phosphorylation and accumulation of GTP-bound p21ras upon antibody-mediated alpha 2 beta 1 integrin activation in T-lymphoblastic cells.
1993
Integrin alpha subunit ratios, cytoplasmic domains, and growth factor synergy regulate muscle proliferation and differentiation.
1996
A systems approach to cancer therapy
1996
Cell type-specific integrin variants with alternative alpha chain cytoplasmic domains.
1991
Mapping in vivo associations of cytoplasmic proteins with integrin beta 1 cytoplasmic domain mutants.
1995
Insoluble fibronectin activates the Na/H antiporter by clustering and immobilizing integrin alpha 5 beta 1, independent of cell shape.
1991
Extracellular matrix alters PDGF regulation of fibroblast integrins.
1996
Neural crest cell locomotion induced by antibodies to β1 integrins A tool for studying the roles of substratum molecular avidity and density in migration
1991
Cell Migration: Integrating Signals from Front to Back
2003 StandoutScience
Rho- and Rac-dependent Assembly of Focal Adhesion Complexes and Actin Filaments in Permeabilized Fibroblasts: An Essential Role for Ezrin/Radixin/Moesin Proteins
1997
Tissue Engineering
1993 StandoutScience
Role of Rac1 and Oxygen Radicals in Collagenase-1 Expression Induced by Cell Shape Change
1998 Science
HMG-1 as a Late Mediator of Endotoxin Lethality in Mice
1999 StandoutScience
FOCAL ADHESIONS, CONTRACTILITY, AND SIGNALING
1996 Standout
The induction of 72-kD gelatinase in T cells upon adhesion to endothelial cells is VCAM-1 dependent.
1994
Integrin dynamics on the tail region of migrating fibroblasts
1996
Signal transduction by integrins: increased protein tyrosine phosphorylation caused by clustering of beta 1 integrins.
1991
Signal transduction from the extracellular matrix.
1993
Lymphocyte Homing and Homeostasis
1996 StandoutScience
Integrins: Versatility, modulation, and signaling in cell adhesion
1992 Standout
Calcium transients induce spatially coordinated increases in traction force during the movement of fish keratocytes
2004
Expression of NG2 proteoglycan causes retention of type VI collagen on the cell surface.
1993
Mechanotransduction Across the Cell Surface and Through the Cytoskeleton
1993 StandoutScience
Laminin receptors in the retina: sequence analysis of the chick integrin alpha 6 subunit. Evidence for transcriptional and posttranslational regulation.
1991
Transforming growth factor beta differentially regulates expression of integrin subunits in guinea pig airway epithelial cells.
1992
Cancer Cell Cycles
1996 StandoutScience
Laminin-binding integrin alpha 7 beta 1: functional characterization and expression in normal and malignant melanocytes.
1991
Tissue Cells Feel and Respond to the Stiffness of Their Substrate
2005 StandoutScience
Survival After Coronary Revascularization Among Patients With Kidney Disease
2004
Integrin-mediated cell adhesion activates mitogen-activated protein kinases.
1994
The vitronectin receptor serves as an accessory molecule for the activation of a subset of gamma/delta T cells.
1991
Human colon carcinoma cells use multiple receptors to adhere to laminin: involvement of alpha 6 beta 4 and alpha 2 beta 1 integrins.
1990
Signal transduction by the platelet integrin alpha IIb beta 3: induction of calcium oscillations required for protein-tyrosine phosphorylation and ligand-induced spreading of stably transfected cells.
1992
Integrin beta 1- and beta 3-mediated endothelial cell migration is triggered through distinct signaling mechanisms.
1993
Integrin cytoplasmic domains mediate inside-out signal transduction
1994
Stromal regulation of epithelial function
1991
Rolling replication of short DNA circles.
1995 StandoutNobel
Exploring and Engineering the Cell Surface Interface
2005 StandoutScience
The extracellular matrix geneFrem1is essential for the normal adhesion of the embryonic epidermis
2004 StandoutNobel
Rho-stimulated contractility drives the formation of stress fibers and focal adhesions.
1996
Integrins and Signal Transduction Pathways: the Road Taken
1995 StandoutScience
Autonomous Expression of a Noncatalytic Domain of the Focal Adhesion-Associated Protein Tyrosine Kinase pp125FAK
1993
Wound Healing--Aiming for Perfect Skin Regeneration
1997 StandoutScience
Integrin Signaling
1999 StandoutScience
Segregation and activation of myosin IIB creates a rear in migrating cells
2008
Cytokines in context.
1991
The assembly of integrin adhesion complexes requires both extracellular matrix and intracellular rho/rac GTPases.
1995
pVHL 19 is a biologically active product of the von Hippel–Lindau gene arising from internal translation initiation
1998 StandoutNobel
Alpha 6 beta 4 integrin heterodimer is a component of hemidesmosomes.
1990
Skeletal myoblasts utilize a novel beta 1-series integrin and not alpha 6 beta 1 for binding to the E8 and T8 fragments of laminin.
1991
Rho GTPases and the Actin Cytoskeleton
1998 StandoutScience
Control of intracellular pH and growth by fibronectin in capillary endothelial cells.
1990
Synthetic peptides from the carboxy-terminal globular domain of the A chain of laminin: their ability to promote cell adhesion and neurite outgrowth, and interact with heparin and the beta 1 integrin subunit.
1991
Probing the integrin-actin linkage using high-resolution protein velocity mapping
2006
Alteration of collagen-dependent adhesion, motility, and morphogenesis by the expression of antisense α2 integrin mrna in mammary cells
1995
Characterization of the integrin alpha v beta 6 as a fibronectin-binding protein.
1992
Growth Factors and Cancer
1991 StandoutScience
Normalization of Tumor Vasculature: An Emerging Concept in Antiangiogenic Therapy
2005 StandoutScience
Integrin recognition of different cell-binding fragments of laminin (P1, E3, E8) and evidence that alpha 6 beta 1 but not alpha 6 beta 4 functions as a major receptor for fragment E8.
1990
Systematic Review: The Comparative Effectiveness of Percutaneous Coronary Interventions and Coronary Artery Bypass Graft Surgery
2007
A hierarchy of ECM-mediated signalling regulates tissue-specific gene expression
1995
Alpha v integrins mediate the rise in intracellular calcium in endothelial cells on fibronectin even though they play a minor role in adhesion
1994
Regulation of development and differentiation by the extracellular matrix
1993
Integrin-associated protein: a 50-kD plasma membrane antigen physically and functionally associated with integrins.
1990
Collagen-induced activation of the M(r) 72,000 type IV collagenase in normal and malignant human fibroblastoid cells.
1992
The major laminin receptor of mouse embryonic stem cells is a novel isoform of the alpha 6 beta 1 integrin.
1991
Cooperative Interactions Between the Caenorhabditis elegans Homeoproteins UNC-86 and MEC-3
1993 StandoutScienceNobel
Paxillin phosphorylation at Ser273 localizes a GIT1–PIX–PAK complex and regulates adhesion and protrusion dynamics
2006
Requirement of Vascular Integrin α v β 3 for Angiogenesis
1994 StandoutScience
Regulation of Myosin Phosphatase by Rho and Rho-Associated Kinase (Rho-Kinase)
1996 StandoutScience
Matrix Metalloproteinases: A Review
1993 Standout
The Molecular Biology of Axon Guidance
1996 StandoutScience
Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions.
1993
Neurexins: Synaptic Cell Surface Proteins Related to the α-Latrotoxin Receptor and Laminin
1992 StandoutScienceNobel
Concanavalin A produces a matrix-degradative phenotype in human fibroblasts. Induction and endogenous activation of collagenase, 72-kDa gelatinase, and Pump-1 is accompanied by the suppression of the tissue inhibitor of matrix metalloproteinases.
1990
2011 ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention
2011 Standout
A Link Between Cyclin A Expression and Adhesion-Dependent Cell Cycle Progression
1993 Science
Integrins as a primary signal transduction molecule regulating monocyte immediate-early gene induction.
1992
Geometric Control of Cell Life and Death
1997 StandoutScience
Fibronectin controls capillary endothelial cell growth by modulating cell shape.
1990
Urokinase Receptor and Fibronectin Regulate the ERKMAPK to p38MAPK Activity Ratios That Determine Carcinoma Cell Proliferation or Dormancy In Vivo
2001
Zyxin and cCRP: two interactive LIM domain proteins associated with the cytoskeleton.
1992
Signal Transduction and Signal Modulation by Cell Adhesion Receptors: The Role of Integrins, Cadherins, Immunoglobulin-Cell Adhesion Molecules, and Selectins
1998
Components of the nuclear signaling cascade that regulate collagenase gene expression in response to integrin-derived signals.
1995
Adhesive properties of the beta 3 integrins: comparison of GP IIb-IIIa and the vitronectin receptor individually expressed in human melanoma cells.
1991
ß-Arrestin 2 Mediates Endocytosis of Type III TGF-ß Receptor and Down-Regulation of Its Signaling
2003 StandoutScienceNobel
Works of Eileen Crowley being referenced
Outcomes of Patients With Chronic Renal Insufficiency in the Bypass Angioplasty Revascularization Investigation
2002
Tyrosine phosphorylation and cytoskeletal tension regulate the release of fibroblast adhesions.
1995
Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression.
1989
Melanoma cell adhesion to basement membrane mediated by integrin-related complexes.
1989
The alpha 1/beta 1 and alpha 6/beta 1 integrin heterodimers mediate cell attachment to distinct sites on laminin.
1990