Citation Impact
Citing Papers
Sustained hypoxia leads to the emergence of cells with enhanced growth, migratory, and promitogenic potentials within the distal pulmonary artery wall
2009
Interleukin-6 Overexpression Induces Pulmonary Hypertension
2008
Remote Ischemic Preconditioning Protects the Brain Against Injury After Hypothermic Circulatory Arrest
2011
Regulation of insulin synthesis and secretion and pancreatic Beta-cell dysfunction in diabetes.
2013
Management of Hyperglycemia in Type 2 Diabetes: A Patient-Centered Approach
2012 Standout
Current knowledge on exosome biogenesis and release
2017 Standout
Genome-wide features of neuroendocrine regulation in Drosophila by the basic helix-loop-helix transcription factor DIMMED
2015 StandoutNobel
The SNARE Proteins SNAP-25 and SNAP-23 Display Different Affinities for Lipid Rafts in PC12 Cells
2004
Nucleotide- and nucleoside-converting ectoenzymes: Important modulators of purinergic signalling cascade
2008 Standout
Munc18-1 Tuning of Vesicle Merger and Fusion Pore Properties
2011 StandoutNobel
Iron-mediated lipid peroxidation and lipid raft disruption in low-dose silica-induced macrophage cytokine production
2011
Glucagon-Like Peptide-1 and Its Class B G Protein–Coupled Receptors: A Long March to Therapeutic Successes
2016
Trends in GPCR drug discovery: new agents, targets and indications
2017 Standout
Targeting oxidative stress in disease: promise and limitations of antioxidant therapy
2021 Standout
PKA Activation Bypasses the Requirement for UNC-31 in the Docking of Dense Core Vesicles from C. elegans Neurons
2007
Neurotransmitter Release: The Last Millisecond in the Life of a Synaptic Vesicle
2013 StandoutNobel
Lipid Raft Association and Cholesterol Sensitivity of P2X1-4 Receptors for ATP
2010
SNAREs Prefer Liquid-disordered over “Raft” (Liquid-ordered) Domains When Reconstituted into Giant Unilamellar Vesicles
2004
Thioredoxin-interacting Protein Mediates High Glucose-induced Reactive Oxygen Species Generation by Mitochondria and the NADPH Oxidase, Nox4, in Mesangial Cells
2013
Efficacy and safety of once-weekly semaglutide monotherapy versus placebo in patients with type 2 diabetes (SUSTAIN 1): a double-blind, randomised, placebo-controlled, parallel-group, multinational, multicentre phase 3a trial
2017
Methyl-β-cyclodextrin reversibly alters the gating of lipid rafts-associated Kv1.3 channels in Jurkat T lymphocytes
2007
IL-6 as a keystone cytokine in health and disease
2015 Standout
Disruption of Lipid Rafts Inhibits P2X1 Receptor-mediated Currents and Arterial Vasoconstriction
2005
Shedding light on the cell biology of extracellular vesicles
2018 Standout
Pancreatic α Cell-Derived Glucagon-Related Peptides Are Required for β Cell Adaptation and Glucose Homeostasis
2017
Metazoan MicroRNAs
2018 Standout
Membrane protein sequestering by ionic protein–lipid interactions
2011 StandoutNatureNobel
Involvement of lipid rafts and caveolae in cardiac ion channel function
2006
Mechanisms of Action and Therapeutic Application of Glucagon-like Peptide-1
2018
The Physiology, Signaling, and Pharmacology of Dopamine Receptors
2011 Standout
Syntaxin‐1 N‐peptide and Habc‐domain perform distinct essential functions in synaptic vesicle fusion
2012 StandoutNobel
Caspase Functions in Cell Death and Disease
2013 Standout
Regulation of the C. elegans molt by pqn-47
2011 StandoutNobel
Disruption of TBP-2 ameliorates insulin sensitivity and secretion without affecting obesity
2010
Transcription Factor NRF2 as a Therapeutic Target for Chronic Diseases: A Systems Medicine Approach
2018 Standout
Caveolin-1 Functions as a Novel Cdc42 Guanine Nucleotide Dissociation Inhibitor in Pancreatic β-Cells
2006
The immunology of stroke: from mechanisms to translation
2011 Standout
Physiology and Pathophysiology of Purinergic Neurotransmission
2007 Standout
Interleukin-1 beta targeted therapy for type 2 diabetes
2009
Conformational Changes Induced in Voltage-gated Calcium Channel Cav1.2 by BayK 8644 or FPL64176 Modify the Kinetics of Secretion Independently of Ca2+ Influx
2010
Epac and PKA: a tale of two intracellular cAMP receptors
2008
The thioredoxin antioxidant system
2013 Standout
The mystery of membrane organization: composition, regulation and roles of lipid rafts
2017 Standout
Uniquantal Release through a Dynamic Fusion Pore Is a Candidate Mechanism of Hair Cell Exocytosis
2014 StandoutNobel
Management of hyperglycaemia in type 2 diabetes: a patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
2012 Standout
Thioredoxin-interacting protein links oxidative stress to inflammasome activation
2009 Standout
The Inflammasomes
2010 Standout
Compound Exocytosis in Pituitary Cells
2009
The role of the thioredoxin/thioredoxin reductase system in the metabolic syndrome: towards a possible prognostic marker?
2018
G protein-coupled receptors as targets for anti-diabetic therapeutics
2016
Type 2 diabetes mellitus
2015 Standout
Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication
2018 Standout
Evidence That Vesicles Undergo Compound Fusion on the Synaptic Ribbon
2008
Cholesterol-Independent Effects of Methyl-β-Cyclodextrin on Chemical Synapses
2012
Incretin-Based Therapies for Type 2 Diabetes Mellitus: Properties, Functions, and Clinical Implications
2010
Inflammation in obesity, diabetes, and related disorders
2022 Standout
Munc18/Syntaxin Interaction Kinetics Control Secretory Vesicle Dynamics
2009
The Myofibroblast
2007 Standout
Thioredoxin Interacting Protein: Redox Dependent and Independent Regulatory Mechanisms
2011
AASLD Practice Guidance on the clinical assessment and management of nonalcoholic fatty liver disease
2023 Standout
Rescue of Munc18-1 and -2 Double Knockdown Reveals the Essential Functions of Interaction between Munc18 and Closed Syntaxin in PC12 Cells
2009
Comparative studies of Munc18c and Munc18-1 reveal conserved and divergent mechanisms of Sec1/Munc18 proteins
2013
Exosomes
2019 Standout
From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus
2009 Standout
Munc18a Scaffolds SNARE Assembly to Promote Membrane Fusion
2008
Epac: Defining a New Mechanism for cAMP Action
2010
Minireview: How Peptide Hormone Vesicles Are Transported to the Secretion Site for Exocytosis
2008
SNARE bundle and syntaxin N-peptide constitute a minimal complement for Munc18-1 activation of membrane fusion
2010 StandoutNobel
Incretin Action in the Pancreas: Potential Promise, Possible Perils, and Pathological Pitfalls
2013
ACC/AHA 2008 Guidelines for the Management of Adults With Congenital Heart Disease
2008 Standout
Routes and mechanisms of extracellular vesicle uptake
2014 Standout
SNAREpin/Munc18 promotes adhesion and fusion of large vesicles to giant membranes
2008 StandoutNobel
Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
2018 Standout
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
ACC/AHA 2008 Guidelines for the Management of Adults With Congenital Heart Disease: Executive Summary
2008 Standout
Munc18-1 binding to the neuronal SNARE complex controls synaptic vesicle priming
2009 StandoutNobel
RAL-1 controls multivesicular body biogenesis and exosome secretion
2015
Pathophysiology of Type 2 Diabetes Mellitus
2020 Standout
Intimal Smooth Muscle Cells of Porcine and Human Coronary Artery Express S100A4, a Marker of the Rhomboid Phenotype In Vitro
2007
Incretins and the development of type 2 diabetes
2006
Reactive Oxygen Species-Induced Lipid Peroxidation in Apoptosis, Autophagy, and Ferroptosis
2019 Standout
Reactive Oxygen Species in Metabolic and Inflammatory Signaling
2018 Standout
Receptors for Purines and Pyrimidines
2012 Standout
Pathobiology of Pulmonary Hypertension
2007
Thioredoxin‐interacting protein deficiency induces Akt/Bcl‐xL signaling and pancreatic beta‐cell mass and protects against diabetes
2008
Hypoxia-Inducible Factor 1α Is a Critical Downstream Mediator for Hypoxia-Induced Mitogenic Factor (FIZZ1/RELMα)–Induced Pulmonary Hypertension
2015 StandoutNobel
Pulmonary arterial remodeling induced by a Th2 immune response
2008
SNAREs can promote complete fusion and hemifusion as alternative outcomes
2005 StandoutNobel
Pancreatic β-Cell Electrical Activity and Insulin Secretion: Of Mice and Men
2017
Targeting the gastrointestinal tract to treat type 2 diabetes
2016
Regulation of Insulin Synthesis and Secretion and Pancreatic Beta-Cell Dysfunction in Diabetes
2012
UNC-18 Promotes Both the Anterograde Trafficking and Synaptic Function of Syntaxin
2008
The Membrane Fusion Enigma: SNAREs, Sec1/Munc18 Proteins, and Their Accomplices—Guilty as Charged?
2012 StandoutNobel
Lipotoxicity disrupts incretin-regulated human β cell connectivity
2013
Mechanisms of Endocytosis
2009 Standout
Deletion of Pten in Pancreatic β-Cells Protects Against Deficient β-Cell Mass and Function in Mouse Models of Type 2 Diabetes
2010 StandoutNobel
Dual roles of Munc18-1 rely on distinct binding modes of the central cavity with Stx1A and SNARE complex
2011
miR-204 Controls Glucagon-Like Peptide 1 Receptor Expression and Agonist Function
2017
Hyper-Progressive Disease: The Potential Role and Consequences of T-Regulatory Cells Foiling Anti-PD-1 Cancer Immunotherapy
2020 StandoutNobel
Works of Edwin Kwan being referenced
The RalA GTPase Is a Central Regulator of Insulin Exocytosis from Pancreatic Islet Beta Cells
2008
Visualization of Sequential Exocytosis in Rat Pancreatic Islet β Cells
2002
Disruption of Pancreatic β-Cell Lipid Rafts Modifies Kv2.1 Channel Gating and Insulin Exocytosis
2004
Pancreatic GLP-1 receptor activation is sufficient for incretin control of glucose metabolism in mice
2011
High β-cell mass prevents streptozotocin-induced diabetes in thioredoxin-interacting protein-deficient mice
2009
S100A4/Mts1 Produces Murine Pulmonary Artery Changes Resembling Plexogenic Arteriopathy and Is Increased in Human Plexogenic Arteriopathy
2004
Activation of Exchange Protein Directly Activated by Cyclic Adenosine Monophosphate and Protein Kinase A Regulate Common and Distinct Steps in Promoting Plasma Membrane Exocytic and Granule-to-Granule Fusions in Rat Islet β Cells
2007
SNAREing Voltage-Gated K+ and ATP-Sensitive K+ Channels: Tuning β-Cell Excitability with Syntaxin-1A and Other Exocytotic Proteins
2007
Distinct In Vivo Roles of Caspase-8 in β-Cells in Physiological and Diabetes Models
2007
Munc13-1 Deficiency Reduces Insulin Secretion and Causes Abnormal Glucose Tolerance
2006
Munc18-1 Is Critical for Plasma Membrane Localization of Syntaxin1 but Not of SNAP-25 in PC12 Cells
2007
Interaction Between Munc13-1 and RIM Is Critical for Glucagon-Like Peptide-1–Mediated Rescue of Exocytotic Defects in Munc13-1–Deficient Pancreatic β-Cells
2007
Glucagon-Like Peptide 1 Regulates Sequential and Compound Exocytosis in Pancreatic Islet β-Cells
2005