Citation Impact
Citing Papers
Nitrogen substituted cyclic enediynes: synthesis, thermal reactivity and complexation with metal ions
2000
Structure-Based Optimization Strategies for G Protein-Coupled Receptor (GPCR) Allosteric Modulators: A Case Study from Analyses of New Metabotropic Glutamate Receptor 5 (mGlu 5 ) X-ray Structures
2018
Computational design of soluble and functional membrane protein analogues
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Ionotropic and metabotropic glutamate receptor structure and pharmacology
2005
A Multi-Step Continuous Flow Process for the N-Demethylation of Alkaloids
2012
An efficient and convenient Cu(OAc)2/air mediated oxidative coupling of azoles via C–H activation
2009
RIM1α and Interacting Proteins Involved in Presynaptic Plasticity Mediate Prepulse Inhibition and Additional Behaviors Linked to Schizophrenia
2010 StandoutNobel
O2-Dependent Cleavage of DNA by Tetrazomine
1994
Reaching for high-hanging fruit in drug discovery at protein–protein interfaces
2007 StandoutNature
Synthesis and antitumor activity of water-soluble enediyne compounds related to dynemicin a
1997
Small‐Molecule Affinity Ligands for Protein Purification: Combined Computational Enrichment and Automated In‐line Screening of an Optically Encoded Library
2010 StandoutNobel
Mechanochemistry: opportunities for new and cleaner synthesis
2011 Standout
Glutamate and Schizophrenia: Phencyclidine, N‐Methyl‐d‐Aspartate Receptors, and Dopamine–Glutamate Interactions
2007
DNA Cleavage, antiviral and cytotoxic reactions photosensitized by simple enediyne compounds
1993
Recent advances in the transition metal-catalyzed twofold oxidative C–H bond activation strategy for C–C and C–N bond formation
2011 Standout
Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor
2010 StandoutNatureNobel
One Century of Aryne Chemistry
2003 Standout
Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders
2008
The structure and function of G-protein-coupled receptors
2009 StandoutNatureNobel
Strategies for Targeting Protein–Protein Interactions With Synthetic Agents
2005
Interactions with Aromatic Rings in Chemical and Biological Recognition
2003 Standout
Versatile tools in the construction of substituted 2,2′-bipyridines—cross-coupling reactions with tin, zinc and boron compounds
2008
Formation of cis-Enediyne Complexes from Rhenium Alkynylcarbene Complexes
2002
Monofluorination of Organic Compounds: 10 Years of Innovation
2015 Standout
Iron Catalysis in Organic Synthesis
2015 Standout
3d Transition Metals for C–H Activation
2018 Standout
Sequential and domino Sonogashira coupling: Efficient tools for the synthesis of diarylalkynes
2005
Bond Formations between Two Nucleophiles: Transition Metal Catalyzed Oxidative Cross-Coupling Reactions
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The nickel-catalyzed Sonogashira–Hagihara reaction
2003
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
UDFT and MCSCF Descriptions of the Photochemical Bergman Cyclization of Enediynes
2001
Retro-Diels−Alder Femtosecond Reaction Dynamics
1996 StandoutNobel
A revisit to the Hantzsch reaction: Unexpected products beyond 1,4-dihydropyridines
2009
A novel strategy for the synthesis of 2-arylpyridines using one-pot 6π-azaelectrocyclization
2008
An Accurate Description of the Bergman Reaction Using Restricted and Unrestricted DFT: Stability Test, Spin Density, and On-Top Pair Density
2000
The synthesis of a 10-membered benzo-oxadiyne ring
1990
Cross‐Coupling Reactions on Azoles with Two and More Heteroatoms
2006
Efficient and Regioselective Halogenations of 2-Amino-1,3-thiazoles with Copper Salts
2009
Femtosecond Dynamics of Transition States and the Concept of Concertedness: Nitrogen Extrusion of Azomethane Reactions
1998 StandoutNobel
Controlled Acceleration and Inhibition of Bergman Cyclization by Metal Chlorides
1995 Science
Transition Structures of Hydrocarbon Pericyclic Reactions
1992 Standout
Oxidative Coupling between Two Hydrocarbons: An Update of Recent C–H Functionalizations
2015 Standout
Antitumor Antibiotics: Bleomycin, Enediynes, and Mitomycin
2005 Standout
Electronic Control of the Bergman Cycloaromatization: Synthesis and Chemistry of Chloroenediynes
2000
New Palladium‐Catalyzed Domino Reaction with Intramolecular Ring Closure of an N‐(2‐Chloro‐3‐heteroaryl)arylamide: First Synthesis of Oxazolo[4,5‐b]pyrazines
2014
Hydroamination: Direct Addition of Amines to Alkenes and Alkynes
2008 Standout
Molecular design, chemical synthesis, and biological action of enediynes
1992
A Comprehensive History of Arynes in Natural Product Total Synthesis
2012 Standout
Palladium-Catalyzed C–H Bond Direct Alkynylation of 5-Membered Heteroarenes: A Well-Defined Synthetic Route to Azole Derivatives Containing Two Different Alkynyl Groups
2012
A general strategy using η2co2(co)6 acetylene complexes for the synthesis of the enediyne antitumor agents esperamicin, calicheamicin, dy
1994
Ynamides: A Modern Functional Group for the New Millennium
2010 Standout
Gold-Catalyzed Cycloisomerizations of Enynes: A Mechanistic Perspective
2008 Standout
Divergent Enantioselective Synthesis of (−)-Galanthamine and (−)-Morphine
2005
Ortho Effect in the Bergman Cyclization: Comparison of Experimental Approaches and Dissection of Cycloaromatization Kinetics
2006
Enantioselective Total Synthesis of (−)-Galanthamine
2000
Oxidative Nucleobase Modifications Leading to Strand Scission
1998 Standout
Facile Synthesis of 2-Alkynyl Buta-1,3-dienes via Sonogashira Cross-Coupling Methodology
2005
The Sonogashira Reaction: A Booming Methodology in Synthetic Organic Chemistry
2007 Standout
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
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Conceptual Density Functional Theory
2003 Standout
Regioselective synthesis of cytotoxic 4-(1-alkynyl)-substituted 2-(5H)-furanones
2003
Sonogashira–Hagihara Coupling towards Diaryl Alkynes Catalyzed by FeCl3⋅6 H2O/Cationic 2,2'‐Bipyridyl
2012
Occurrence, Biogenesis, and Synthesis of Biologically Active Carbazole Alkaloids
2012 Standout
Carboxylate-Assisted Transition-Metal-Catalyzed C−H Bond Functionalizations: Mechanism and Scope
2011 Standout
Density Functional Study of Bergman Cyclization of Enediynes
1998
Thermolysis of 1,3,8-Nonatriyne: Evidence for Intramolecular [2 + 4] Cycloaromatization to a Benzyne Intermediate
1997
Solvent dependent bergman cyclization of 2,3-diethynylquinoxaline
1999
N-Heterocyclic Carbenes in Late Transition Metal Catalysis
2009 Standout
Chemistry and Biology of the Tetrahydroisoquinoline Antitumor Antibiotics
2002 Standout
Strategien zur Modulation von Protein‐Protein‐Wechselwirkungen mit synthetischen Substanzen
2005
Cyclic enediynes: relationship between ring size, alkyne carbon distance, and cyclization barrier
1998
Ground- and Excited-State Reactions of Norbornene and Isomers: A CASSCF Study and Comparison with Femtosecond Experiments
1999 StandoutNobel
Catalytic Dehydrogenative Cross-Coupling: Forming Carbon−Carbon Bonds by Oxidizing Two Carbon−Hydrogen Bonds
2011 Standout
Aryl−Aryl Bond Formation by Transition-Metal-Catalyzed Direct Arylation
2007 Standout
Eine neue Diradikal‐Cyclisierung als Alternative zur Myers‐Saito‐Cycloaromatisierung bei der thermischen Umsetzung von Eninallenen
1996
Helicenes: Synthesis and Applications
2011 Standout
Methyl 4‐Hydroxy‐5‐iodo‐2,3‐dimethoxy‐6‐methylbenzoate: The Aromatic Fragment of Calichemicin γ. Synthesis, X‐Ray Crystallographic Analysis, and Properties
1988
A Surprising Switch from the Myers–Saito Cyclization to a Novel Biradical Cyclization in Enyne–Allenes: Formal Diels–Alder and Ene Reactions with High Synthetic Potential
1997
1,4‐Didehydronaphthalin
1996
Femtosecond β-cleavage dynamics: Observation of the diradical intermediate in the nonconcerted reactions of cyclic ethers
1998 StandoutNobel
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Benzannelation alters the rate limiting step in enediyne cycloaromatization
1999
A Field Guide to Foldamers
2001 Standout
Synthesis and reactivity of enediynyl amino acids and peptides: a novel concept in lowering the activation energy of Bergman cyclisation by H-bonding and electrostatic interactions
2003
Aerobic Copper-Catalyzed Organic Reactions
2013 Standout
Benzannelation Effect on Enediyne Cycloaromatization: An ab Initio Molecular Orbital Study
1999
Chelation-Controlled Bergman Cyclization: Synthesis and Reactivity of Enediynyl Ligands
2003
Electronic Control of the Bergman Cyclization: The Remarkable Role of Vinyl Substitution
2001
Organic Reactions in Aqueous Media with a Focus on Carbon−Carbon Bond Formations: A Decade Update
2005 Standout
Synthesis and properties of novel thiaarenecyclynes
2003
Cascade Radical Cyclizations via Biradicals Generated from Enediynes, Enyne-Allenes, and Enyne-Ketenes
1996
Propargylic Sulfone-Armed Lariat Crown Ethers: Alkali Metal Ion-Regulated DNA Cleavage Agents
2000
Large-Scale Applications of Transition Metal-Catalyzed Couplings for the Synthesis of Pharmaceuticals
2011 Standout
Regioselective cross-coupling reactions of multiple halogenated nitrogen-, oxygen-, and sulfur-containing heterocycles
2004
Photochemische Cycloaromatisierung nichtbenzoider Endiine
1999
Biradical formation from acyclic conjugated eneyne-allene system related to neocarzinostatin and esperamicin-calichemicin
1989
Enantioconvergent synthesis of a promising HMG CoA reductase inhibitor NK-104 from both enantiomers of epichlorohydrin
1993
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
On the Mechanism of Quinone Formation from the Bergman Cyclization: Some Theoretical Insights
2001
Structure and stability of enediynes containing heteroatoms—a quantum chemical investigation
2000
Chemie und Biologie von Endiin‐Cytostatica/Antibiotica
1991
Switching from the Myers reaction to a new thermal cyclization mode in enyne-allenes
1995
Cyclic conjugated enediynes via elimination of a thionocarbonate in a latent Z-hex-3-ene-1,5-diyne unit
1993
Nucleus-Independent Chemical Shifts (NICS) as an Aromaticity Criterion
2005 Standout
Intramolecular 1,3-dipolar nitrone cycloaddition route to bicyclic fused enediyne
2005
Substituent effects on the Bergman cyclization of (Z)‐1,5‐hexadiyne‐3‐enes: a systematic computational study
2001
From 2000 to Mid-2010: A Fruitful Decade for the Synthesis of Pyrazoles
2011 Standout
Designed Enediynes: A New Class of DNA-Cleaving Molecules with Potent and Selective Anticancer Activity
1992 Science
Chemistry and Biology of the Enediyne Anticancer Antibiotics
1991 Standout
Application of recoverable nanosized palladium(0) catalyst in Sonogashira reaction
2005
An Unprecedented Biradical Cyclization as an Alternative Pathway to the Myers–Saito Cycloaromatization in the Thermal Reactions of Enyne Allenes
1996
Stereoselective syntheses of di-, tri-, and tetrasubstituted enediynes from enynyl iodides via Pd-catalyzed coupling reactions
1991
An Amine‐, Copper‐ and Phosphine‐Free Sonogashira Coupling Reaction Catalyzed by Immobilization of Palladium in Organic–Inorganic Hybrid Materials
2006
Computer Design of Anticancer Drugs. A New Enediyne Warhead
2000
Some Typical Advances in the Synthetic Applications of Allenes
2005 Standout
Synthesis and Structure−Activity Relationships of 3-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]pyridine Analogues as Potent, Noncompetitive Metabotropic Glutamate Receptor Subtype 5 Antagonists; Search for Cocaine Medications
2006
Clean Inversion of Configuration in the Pd-Catalyzed Cross-Coupling of 2-Bromo-1,3-dienes
2003 StandoutNobel
Crown Ethers: Sensors for Ions and Molecular Scaffolds for Materials and Biological Models
2004 Standout
Design, Synthesis, and Structure−Activity Relationships of Novel Bicyclic Azole-amines as Negative Allosteric Modulators of Metabotropic Glutamate Receptor 5
2010
Photoinduced Bergman cycloaromatization of imidazole-fused enediynes
2005
Synthesis and thermal reactivity of a novel macrocyclic enediyne and its copper(II) complex
1998
Silver-Catalyzed Csp−H and Csp−Si Bond Transformations and Related Processes
2008
Metal-Free Multicomponent Syntheses of Pyridines
2014 Standout
Asymmetric Transition-Metal-Catalyzed Allylic Alkylations: Applications in Total Synthesis
2003 Standout
Works of Edwin J. Schweiger being referenced
5-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]-2,3′-bipyridine: a highly potent, orally active metabotropic glutamate subtype 5 (mGlu5) receptor antagonist with anxiolytic activity
2004
[3H]-Methoxymethyl-MTEP and [3H]-Methoxy-PEPy: potent and selective radioligands for the metabotropic glutamate subtype 5 (mGlu5) receptor
2003
Design and Synthesis of a Competent Pyrrolinone−Peptide Hybrid Ligand for the Class II Major Histocompatibility Complex Protein HLA-DR1
1999
A New Class of DNA‐Cleaving Molecules: pH‐Dependent DNA Cleavage by Propargylic and Allenic Sulfones
1989
Cyclic conjugated enediynes related to calicheamicins and esperamicins: calculations, synthesis, and properties
1988
Synthesis and biological activity of galanthamine derivatives as acetylcholinesterase (AChE) inhibitors
1991
Chemical and pharmacological characterization of galanthamine, an acetylcholinesterase inhibitor, and its derivatives. A potential application in Alzheimer's disease?
1992
Eine neue Klasse DNA‐spaltender Verbindungen: pH‐abhängige DNA‐Spaltung durch Propargyl‐ und Allenylsulfone
1989
3-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]- pyridine: A Potent and Highly Selective Metabotropic Glutamate Subtype 5 Receptor Antagonist with Anxiolytic Activity
2002