Citation Impact
Citing Papers
Hippo signaling disruption and Akt stimulation of ovarian follicles for infertility treatment
2013 Standout
Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation
2013 StandoutScience
TEAD Transcription Factors Mediate the Function of TAZ in Cell Growth and Epithelial-Mesenchymal Transition
2009
Using the Neandertal genome to study the evolution of small insertions and deletions in modern humans
2017
An integrated encyclopedia of DNA elements in the human genome
2012 StandoutNature
The Hippo Pathway Promotes Notch Signaling in Regulation of Cell Differentiation, Proliferation, and Oocyte Polarity
2008
Cancer Invasion and the Microenvironment: Plasticity and Reciprocity
2011 Standout
The Mechanosensitive Ion Channel Piezo Inhibits Axon Regeneration
2019 StandoutNobel
Chromatin Immunoprecipitation Indirect Peaks Highlight Long-Range Interactions of Insulator Proteins and Pol II Pausing
2014
Syndromes Associated with Insulin Resistance and Acanthosis Nigricans
1998
deepTools2: a next generation web server for deep-sequencing data analysis
2016 Standout
A Mechanical Checkpoint Controls Multicellular Growth through YAP/TAZ Regulation by Actin-Processing Factors
2013 Standout
Filling out the Hippo pathway
2007
The TEAD/TEF Family Protein Scalloped Mediates Transcriptional Output of the Hippo Growth-Regulatory Pathway
2008
Forces in Tissue Morphogenesis and Patterning
2013 Standout
Yap1 Acts Downstream of α-Catenin to Control Epidermal Proliferation
2011
YAP mediates crosstalk between the Hippo and PI(3)K–TOR pathways by suppressing PTEN via miR-29
2012
NDR kinases regulate essential cell processes from yeast to humans
2006
Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function
2017
Crossing paths with Notch in the hyper-network
2007
Salt-inducible kinases regulate growth through the Hippo signalling pathway in Drosophila
2012
Shedding light on Merlin's wizardry
2007
Molecular Mechanisms of Human Hypertension
2001 Standout
From Cell Structure to Transcription: Hippo Forges a New Path
2006
Origins and Mechanisms of miRNAs and siRNAs
2009 Standout
Insulin Resistance — Mechanisms, Syndromes, and Implications
1991
A microRNA Mediates EGF Receptor Signaling and Promotes Photoreceptor Differentiation in the Drosophila Eye
2005
Identification of Happyhour/MAP4K as Alternative Hpo/Mst-like Kinases in the Hippo Kinase Cascade
2015
The Drosophila tumor suppressors Expanded and Merlin differentially regulate cell cycle exit, apoptosis, and Wingless signaling
2006
Protein kinase A activates the Hippo pathway to modulate cell proliferation and differentiation
2013
The Emerging Role of the Hippo Pathway in Cell Contact Inhibition, Organ Size Control, and Cancer Development in Mammals
2008
Delineation of a Fat tumor suppressor pathway
2006
MicroRNAs: Target Recognition and Regulatory Functions
2009 Standout
A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCFβ-TRCP
2010
Mob as tumor suppressor is activated by Hippo kinase for growth inhibition in Drosophila
2007
Tracking Multiple Genomic Elements Using Correlative CRISPR Imaging and Sequential DNA FISH
2017
Fat Cadherin Modulates Organ Size in Drosophila via the Salvador/Warts/Hippo Signaling Pathway
2006
Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer
2015 Standout
Combined Functional Genomic and Proteomic Approaches Identify a PP2A Complex as a Negative Regulator of Hippo Signaling
2010
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
The bantam MicroRNA Is a Target of the Hippo Tumor-Suppressor Pathway
2006
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets
2017 StandoutNobel
The Hippo Signaling Pathway in Development and Cancer
2010 Standout
High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis
1993 Standout
Point mutation causing a single amino acid substitution in the hormone binding domain of the glucocorticoid receptor in familial glucocorticoid resistance.
1991
The YAP and TAZ transcription co-activators: Key downstream effectors of the mammalian Hippo pathway
2012
The Hippo Signaling Pathway Coordinately Regulates Cell Proliferation and Apoptosis by Inactivating Yorkie, the Drosophila Homolog of YAP
2005 Standout
The Fat Cadherin Acts through the Hippo Tumor-Suppressor Pathway to Regulate Tissue Size
2006
The TEAD/TEF Family of Transcription Factor Scalloped Mediates Hippo Signaling in Organ Size Control
2008
Odorant Receptors Govern the Formation of a Precise Topographic Map
1998 StandoutNobel
Polycystic Ovary Syndrome
1995 Standout
TEAD mediates YAP-dependent gene induction and growth control
2008 Standout
A role for microRNAs in the Drosophila circadian clock
2009 StandoutNobel
Systematic Protein Location Mapping Reveals Five Principal Chromatin Types in Drosophila Cells
2010
The Hippo Tumor Pathway Promotes TAZ Degradation by Phosphorylating a Phosphodegron and Recruiting the SCFβ-TrCP E3 Ligase
2010
Beyond genetics: epigenetic code in chronic kidney disease
2010
The Hippo pathway: regulators and regulations
2013
A novel partner of Scalloped regulates Hippo signaling via antagonizing Scalloped-Yorkie activity
2013
Modulating F‐actin organization induces organ growth by affecting the Hippo pathway
2011
Architectural Protein Subclasses Shape 3D Organization of Genomes during Lineage Commitment
2013
Hippo signaling regulates Yorkie nuclear localization and activity through 14-3-3 dependent and independent mechanisms
2009
The N-terminal Phosphodegron Targets TAZ/WWTR1 Protein for SCFβ-TrCP-dependent Degradation in Response to Phosphatidylinositol 3-Kinase Inhibition
2012
The Merlin/NF2 Tumor Suppressor Functions through the YAP Oncoprotein to Regulate Tissue Homeostasis in Mammals
2010
Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control
2007 Standout
Mechanisms linking obesity to insulin resistance and type 2 diabetes
2006 StandoutNature
SCALLOPED Interacts with YORKIE, the Nuclear Effector of the Hippo Tumor-Suppressor Pathway in Drosophila
2008
A MicroRNA Imparts Robustness against Environmental Fluctuation during Development
2009
Analysis of variation at transcription factor binding sites in Drosophila and humans
2012
The Cell Adhesion Molecule Echinoid Functions as a Tumor Suppressor and Upstream Regulator of the Hippo Signaling Pathway
2012
Insulin signalling and the regulation of glucose and lipid metabolism
2001 StandoutNature
Hippo signaling in organ size control
2007
The Hippo Pathway Regulates the bantam microRNA to Control Cell Proliferation and Apoptosis in Drosophila
2006
MOBKL1A/MOBKL1B Phosphorylation by MST1 and MST2 Inhibits Cell Proliferation
2008
The tumour suppressor Hippo acts with the NDR kinases in dendritic tiling and maintenance
2006 Nature
Ajuba LIM Proteins Are Negative Regulators of the Hippo Signaling Pathway
2010
Detection of mutations in the insulin receptor gene in patients with insulin resistance by analysis of single-stranded conformational polymorphisms
1992
Kibra Functions as a Tumor Suppressor Protein that Regulates Hippo Signaling in Conjunction with Merlin and Expanded
2010
Mob as tumor suppressor is activated at the cell membrane to control tissue growth and organ size in Drosophila
2009
Modification of Enhancer Chromatin: What, How, and Why?
2013
NDR Kinase Is Activated by RASSF1A/MST1 in Response to Fas Receptor Stimulation and Promotes Apoptosis
2008
Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis
2012
Kibra Is a Regulator of the Salvador/Warts/Hippo Signaling Network
2010
The Hippo signaling pathway and stem cell biology
2012
The Salvador–Warts–Hippo pathway — an emerging tumour-suppressor network
2007
Chromatin Landscape Dictates HSF Binding to Target DNA Elements
2010
Subnuclear segregation of genes and core promoter factors in myogenesis
2011 StandoutNobel
The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis
2005
Genetics of Type 2 diabetes
2005
Expression of Yes-associated protein in common solid tumors
2008
The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism
2009 Standout
CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
2013 StandoutNobel
Three-Dimensional Folding and Functional Organization Principles of the Drosophila Genome
2012
Tumor Suppressor LATS1 Is a Negative Regulator of Oncogene YAP
2007
The FERM-Domain Protein Expanded Regulates Hippo Pathway Activity via Direct Interactions with the Transcriptional Activator Yorkie
2009
Topological domains in mammalian genomes identified by analysis of chromatin interactions
2012 StandoutNature
Structural basis of YAP recognition by TEAD4 in the Hippo pathway
2010
A crucial role of WW45 in developing epithelial tissues in the mouse
2008
Atherosclerosis
2001 Standout
A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping
2014 Standout
Warts Is Required for PI3K-Regulated Growth Arrest, Autophagy, and Autophagic Cell Death in Drosophila
2008
Spatial partitioning of the regulatory landscape of the X-inactivation centre
2012 StandoutNature
Chronic Kidney Disease
2016 Standout
The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal
2011
Elucidation of a Universal Size-Control Mechanism in Drosophila and Mammals
2007 Standout
Role of YAP/TAZ in mechanotransduction
2011 StandoutNature
miR-14 Regulates Autophagy during Developmental Cell Death by Targeting ip3-kinase 2
2014 StandoutNobel
CLOCK:BMAL1 is a pioneer-like transcription factor
2014 StandoutNobel
Organoid single-cell genomic atlas uncovers human-specific features of brain development
2019 StandoutNatureNobel
Leptin Inhibits Bone Formation through a Hypothalamic Relay
2000 Standout
Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes
2013 Standout
Growth Control by Committee: Intercellular Junctions, Cell Polarity, and the Cytoskeleton Regulate Hippo Signaling
2012
Gene insulation. Part I: natural strategies in yeast and Drosophila
2010
The Growth Regulators warts/lats and melted Interact in a Bistable Loop to Specify Opposite Fates in Drosophila R8 Photoreceptors
2005
Structural and functional analysis of the YAP-binding domain of human TEAD2
2010
Regulation of Imaginal Disc Growth by Tumor-Suppressor Genes in Drosophila
2006
Genomes in Focus: Development and Applications of CRISPR‐Cas9 Imaging Technologies
2017 StandoutNobel
YAP1, the nuclear target of Hippo signaling, stimulates heart growth through cardiomyocyte proliferation but not hypertrophy
2012
Hippo Pathway Regulation of Gastrointestinal Tissues
2014
A feedback circuit involving let-7-family miRNAs and DAF-12 integrates environmental signals and developmental timing in Caenorhabditis elegans
2009 StandoutNobel
Brahma is essential for Drosophila intestinal stem cell proliferation and regulated by Hippo signaling
2013
TAZ Promotes Cell Proliferation and Epithelial-Mesenchymal Transition and Is Inhibited by the Hippo Pathway
2008
A nonsense mutation causing decreased levels of insulin receptor mRNA: detection by a simplified technique for direct sequencing of genomic DNA amplified by the polymerase chain reaction.
1990
THE LDL RECEPTOR LOCUS IN FAMILIAL HYPERCHOLESTEROLEMIA: Mutational Analysis of a Membrane Protein
1990 Nobel
Spermidine in health and disease
2018 StandoutScience
The Hippo pathway regulates intestinal stem cell proliferation duringDrosophilaadult midgut regeneration
2010
Fas Preassociation Required for Apoptosis Signaling and Dominant Inhibition by Pathogenic Mutations
2000 StandoutScienceNobel
Actin-Capping Protein and the Hippo pathway regulate F-actin and tissue growth in Drosophila
2011
Human Diabetes Associated with a Mutation in the Tyrosine Kinase Domain of the Insulin Receptor
1989 Science
Spermidine Enhances the Silk Production by Mulberry Silkworm
2014
Mammalian Tead proteins regulate cell proliferation and contact inhibition as transcriptional mediators of Hippo signaling
2008
Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance
1993 StandoutScience
Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression
2010
Investigation of the mechanism of the dominant negative effect of mutations in the tyrosine kinase domain of the insulin receptor.
1994
W mutant mice with mild or severe developmental defects contain distinct point mutations in the kinase domain of the c-kit receptor.
1990
Transforming properties of YAP , a candidate oncogene on the chromosome 11q22 amplicon
2006
daf-2 , an Insulin Receptor-Like Gene That Regulates Longevity and Diapause in Caenorhabditis elegans
1997 StandoutScienceNobel
Redundant Roles of Tead1 and Tead2 in Notochord Development and the Regulation of Cell Proliferation and Survival
2008
Human LATS1 Is a Mitotic Exit Network Kinase
2005
The Caenorhabditis elegans gene mek-2 is required for vulval induction and encodes a protein similar to the protein kinase MEK.
1995 StandoutNobel
Downstream of Mutant KRAS, the Transcription Regulator YAP Is Essential for Neoplastic Progression to Pancreatic Ductal Adenocarcinoma
2014
Differential requirement of Salvador-Warts-Hippo pathway members for organ size control in Drosophila melanogaster
2010
Caenorhabditis elegans microRNAs of the let-7 family act in innate immune response circuits and confer robust developmental timing against pathogen stress
2015 StandoutNobel
IRS-1-Mediated Inhibition of Insulin Receptor Tyrosine Kinase Activity in TNF-α- and Obesity-Induced Insulin Resistance
1996 StandoutScience
Hippo signaling: growth control and beyond
2010
Clinical significance of the loss of MATS1 mRNA expression in colorectal cancer
2007
Mammalian Hippo signalling: a kinase network regulated by protein–protein interactions
2012
Works of Edward Ramos being referenced
Tissue-specific variation in DNA methylation levels along human chromosome 1
2009
Distinct isoforms of the Drosophila Brd4 homologue are present at enhancers, promoters and insulator sites
2013
DNA Topoisomerase II Modulates Insulator Function in Drosophila
2011
Drosophila CTCF tandemly aligns with other insulator proteins at the borders of H3K27me3 domains
2012
Regulation of Chromatin Organization and Inducible Gene Expression by a Drosophila Insulator
2011
Genomic Organization of gypsy Chromatin Insulators in Drosophila melanogaster
2006
Genome-wide association study identifies novel loci association with fasting insulin and insulin resistance in African Americans
2012
Notch Activation of yan Expression Is Antagonized by RTK/Pointed Signaling in the Drosophila Eye
2002
Control of Cell Proliferation and Apoptosis by Mob as Tumor Suppressor, Mats
2005
Genome-wide phosphoacetylation of histone H3 at Drosophila enhancers and promoters
2012
Three subclasses of a Drosophila insulator show distinct and cell type-specific genomic distributions
2009
A mutation in the insulin receptor gene that impairs transport of the receptor to the plasma membrane and causes insulin-resistant diabetes.
1989