Standout Papers

The crystal structure of cyclin A 1995 2026 2005 2015 159
  1. The crystal structure of cyclin A (1995)
    M.E.M. Noble, Jane Endicott et al. Structure

Citation Impact

Citing Papers

Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
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Formylglycine-generating enzyme binds substrate directly at a mononuclear Cu(I) center to initiate O 2 activation
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Crystal Structure of Rhodopsin: A G Protein-Coupled Receptor
2000 StandoutScience
Actin retrograde flow actively aligns and orients ligand-engaged integrins in focal adhesions
2017 StandoutNobel
Focal adhesions are sites of integrin extension
2010
Tight and specific lanthanide binding in a de novo TIM barrel with a large internal cavity designed by symmetric domain fusion
2020 StandoutNobel
The Novel S527F Mutation in the Integrin β3 Chain Induces a High Affinity αIIbβ3 Receptor by Hindering Adoption of the Bent Conformation
2009
Intermediate Trapping on a Mutant Retaining α-Galactosyltransferase Identifies an Unexpected Aspartate Residue
2004
Discovery of archaeal fusexins homologous to eukaryotic HAP2/GCS1 gamete fusion proteins
2022 StandoutNobel
Linking integrin conformation to function
2008
Modulation of Integrin Activation by an Entropic Spring in the β-Knee
2010 StandoutNobel
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
2009 StandoutNobel
Insights into low molecular mass organic gelators: a focus on drug delivery and tissue engineering applications
2013
From molecular to modular cell biology
1999 StandoutNatureNobel
Crystal Structure of the Autocatalytic Initiator of Glycogen Biosynthesis, Glycogenin
2002
Crystal Structure of the Retinoblastoma Protein N Domain Provides Insight into Tumor Suppression, Ligand Interaction, and Holoprotein Architecture
2007
The cancer glycocalyx mechanically primes integrin-mediated growth and survival
2014 StandoutNatureNobel
The Tn Antigen—Structural Simplicity and Biological Complexity
2011
Oligosaccharide substrate binding in Escherichia coli maltodextrin phosphorylase
1997
Self-assembly of Fmoc-diphenylalanine inside liquid marbles
2012
Mucins, Mucus, and Sputum
2009
Crystal structure refinement withSHELXL
2014 Standout
Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis
2016 StandoutNobel
Catalytic Asymmetric Conjugate Addition/Oxidative Dearomatization Towards Multifunctional Spirocyclic Compounds
2011 StandoutNobel
A chemoenzymatic approach toward the identification of fucosylated glycoproteins and mapping of N-glycan sites
2011
Phosphorylase recognition and phosphorolysis of its oligosaccharide substrate: answers to a long outstanding question
1999
Structure-guided evolution of cyan fluorescent proteins towards a quantum yield of 93%
2012
The MORPHEUS protein crystallization screen
2009
Insights into the Synthesis of Lipopolysaccharide and Antibiotics through the Structures of Two Retaining Glycosyltransferases from Family GT4
2006
Zinc‐Triggered Hydrogelation of a Self‐Assembling β‐Hairpin Peptide
2011
Structure-guided mutagenesis of a mucin-selective metalloprotease from Akkermansia muciniphila alters substrate preferences
2022 StandoutNobel
A functional and structural study of the major metalloprotease secreted by the pathogenic fungusAspergillus fumigatus
2013
The importance of the self-assembly process to control mechanical properties of low molecular weight hydrogels
2013
Crystal Structures of the T4 Phage β-Glucosyltransferase and the D100A Mutant in Complex with UDP-glucose: Glucose Binding and Identification of the Catalytic Base for a Direct Displacement Mechanism
2003
Rational design of α-helical tandem repeat proteins with closed architectures
2015 StandoutNatureNobel
Trehalose Is Required for Growth of Mycobacterium smegmatis
2004 StandoutNobel
Reconstruction of Functional β-Propeller Lectins via Homo-oligomeric Assembly of Shorter Fragments
2006
Aromatic peptide amphiphiles: significance of the Fmoc moiety
2013
Electron Crystal Structure of the Transcription Factor and DNA Repair Complex, Core TFIIH
2000 StandoutNobel
Metabolic Labeling of Sialic Acids in Living Animals with Alkynyl Sugars
2009 StandoutNobel
Refinement of macromolecular structures against neutron data withSHELXL2013
2013
Self-assembly of short peptides to form hydrogels: Design of building blocks, physical properties and technological applications
2013
Structural basis for the drug extrusion mechanism by a MATE multidrug transporter
2013 Nature
Active and Inactive Protein Kinases: Structural Basis for Regulation
1996
Glycosylation in health and disease
2019
Insights into Trehalose Synthesis Provided by the Structure of the Retaining Glucosyltransferase OtsA
2002
Structural Evidence of a Passive Base-flipping Mechanism for AGT, an Unusual GT-B Glycosyltransferase
2005
Structure of an integrin with an αI domain, complement receptor type 4
2009
Protein, lipid and water organization in bacteriorhodopsin crystals: a molecular view of the purple membrane at 1.9 Å resolution
1999
Structural and Electronic Snapshots during the Transition from a Cu(II) to Cu(I) Metal Center of a Lytic Polysaccharide Monooxygenase by X-ray Photoreduction
2014
The structure of the integrin αIIbβ3 transmembrane complex explains integrin transmembrane signalling
2009
Lectin-Based Glycoproteomic Techniques for the Enrichment and Identification of Potential Biomarkers
2010
The structure of cyclin H: common mode of kinase activation and specific features
1997
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
2003 StandoutNature
Synthesis and Microcontact Printing of Dual End‐Functionalized Mucin‐like Glycopolymers for Microarray Applications
2009 StandoutNobel
Dipeptide hydrogelation triggered via ultraviolet light
2012
Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH
2022 StandoutNobel
Exploring the repeat protein universe through computational protein design
2015 StandoutNatureNobel
Lectin Domains of Polypeptide GalNAc Transferases Exhibit Glycopeptide Binding Specificity
2011 StandoutNobel
Structure of a Complete Integrin Ectodomain in a Physiologic Resting State and Activation and Deactivation by Applied Forces
2008
Crystal structure of the retaining galactosyltransferase LgtC from Neisseria meningitidis in complex with donor and acceptor sugar analogs.
2001
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
One Step Closer to a Sweet Conclusion
2002
Intact αIIbβ3 Integrin Is Extended after Activation as Measured by Solution X-ray Scattering and Electron Microscopy
2011
Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21
2015 StandoutNobel
Accurate design of megadalton-scale two-component icosahedral protein complexes
2016 StandoutScienceNobel
The Unexpected Importance of the Primary Structure of the Hydrophobic Part of One-Component Ionizable Amphiphilic Janus Dendrimers in Targeted mRNA Delivery Activity
2022 StandoutNobel
The effect of solvent choice on the gelation and final hydrogel properties of Fmoc–diphenylalanine
2014
Investigating Cell Surface Galectin-Mediated Cross-Linking on Glycoengineered Cells
2012 StandoutNobel
A synthon approach to spiro compounds
2005
Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists
1999 StandoutNobel
Targeted and Equally Distributed Delivery of mRNA to Organs with Pentaerythritol-Based One-Component Ionizable Amphiphilic Janus Dendrimers
2023 StandoutNobel
Supramolecular Hydrogelators and Hydrogels: From Soft Matter to Molecular Biomaterials
2015 Standout
Density Variant Glycan Microarray for Evaluating Cross-Linking of Mucin-like Glycoconjugates by Lectins
2012 StandoutNobel
Phosphonate and α-Fluorophosphonate Analogue Probes of the Ionization State of Pyridoxal 5‘-Phosphate (PLP) in Glycogen Phosphorylase
1996
Seamless Metallic Coating and Surface Adhesion of Self-Assembled Bioinspired Nanostructures Based on Di-(3,4-dihydroxy-l-phenylalanine) Peptide Motif
2014
Microarrays with Varying Carbohydrate Density Reveal Distinct Subpopulations of Serum Antibodies
2009
Copper-free click chemistry for dynamic in vivo imaging
2007 StandoutNobel
One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA
2021 StandoutNobel
Silver mineralization on self-assembled peptide nanofibers for long term antimicrobial effect
2011
Crystal Structure of an Archaeal Glycogen Synthase
2005
Gelation properties of self-assembling N-acyl modified cytidine derivatives
2014
Impact of β2 integrin deficiency on mouse natural killer cell development and function
2011 StandoutNobel
Computational design of a self-assembling symmetrical β-propeller protein
2014
Fluorogenic Azidofluoresceins for Biological Imaging
2012 StandoutNobel
Imaging bacterial peptidoglycan with near-infrared fluorogenic azide probes
2014 StandoutNobel
Functional π-Gelators and Their Applications
2014 Standout
CYCLIN-DEPENDENT KINASES: Engines, Clocks, and Microprocessors
1997 Standout
The effect of polymer additives on the rheological properties of dipeptide hydrogelators
2012
Nanoscale dynamics and aging of fibrous peptide-based gels
2014
Differential Self-Assembly and Tunable Emission of Aromatic Peptide Bola-Amphiphiles Containing Perylene Bisimide in Polar Solvents Including Water
2014
A systematic dissection of determinants and consequences of snoRNA-guided pseudouridylation of human mRNA
2022 StandoutNobel
Targeted Delivery of mRNA with One-Component Ionizable Amphiphilic Janus Dendrimers
2021 StandoutNobel
Structural Mechanism for STI-571 Inhibition of Abelson Tyrosine Kinase
2000 StandoutScience
Two approaches for the engineering of homogeneous small-molecule hydrogels
2013
Imaging the glycome
2008 StandoutNobel
Development of orally active inhibitors of protein and cellular fucosylation
2013
Evidence for equilibrium gels of valence-limited particles
2014
Substrate recruitment to cyclin-dependent kinase 2 by a multipurpose docking site on cyclin A
1998
De Novo Carborane-Containing Macrocyclic Peptides Targeting Human Epidermal Growth Factor Receptor
2019 StandoutNobel
Assessing the Utility of Infrared Spectroscopy as a Structural Diagnostic Tool for β-Sheets in Self-Assembling Aromatic Peptide Amphiphiles
2013
Phenylalanine-containing cyclic dipeptides – the lowest molecular weight hydrogelators based on unmodified proteinogenic amino acids
2013
Mimicking Complex Biological Membranes and Their Programmable Glycan Ligands with Dendrimersomes and Glycodendrimersomes
2017
The influence of the kinetics of self-assembly on the properties of dipeptide hydrogels
2013
Cytidine 5‘-Monophosphate (CMP)-Induced Structural Changes in a Multifunctional Sialyltransferase from Pasteurella multocida,
2006
Glycosyltransferases: Structures, Functions, and Mechanisms
2007 Standout
Pickering Stabilized Peptide Gel Particles as Tunable Microenvironments for Biocatalysis
2013
Noncovalent Cell Surface Engineering: Incorporation of Bioactive Synthetic Glycopolymers into Cellular Membranes
2008 StandoutNobel
Second-Generation Difluorinated Cyclooctynes for Copper-Free Click Chemistry
2008 StandoutNobel
CalFluors: A Universal Motif for Fluorogenic Azide Probes across the Visible Spectrum
2015 StandoutNobel
Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells
2007
Real-Time Bioluminescence Imaging of Glycans on Live Cells
2010 StandoutNobel
Salt-induced hydrogels from functionalised-dipeptides
2013
Chemical Glycoproteomics
2016 StandoutNobel
An Array-Based Method To Identify Multivalent Inhibitors
2010

Works of Edward P. Mitchell being referenced

The ID23-1 structural biology beamline at the ESRF
2006
Structural basis for recognition of breast and colon cancer epitopes Tn antigen and Forssman disaccharide by Helix pomatia lectin
2007
Near‐Atomic Resolution Neutron Crystallography on Perdeuterated Pyrococcus furiosus Rubredoxin: Implication of Hydronium Ions and Protonation State Equilibria in Redox Changes
2012
Isolectins I-A and I-B of Griffonia(Bandeiraea) simplicifolia
2002
Crystal Structure of Fungal Lectin
2003
Design of metal‐binding sites onto self‐assembled peptide fibrils
2009
Structural basis for oligosaccharide-mediated adhesion of Pseudomonas aeruginosa in the lungs of cystic fibrosis patients
2002
Structural basis of calcium and galactose recognition by the lectin PA‐IL of Pseudomonas aeruginosa
2003
A Structural Hypothesis for the Transition between Bent and Extended Conformations of the Leukocyte β2 Integrins
2007
The ID23-2 structural biology microfocus beamline at the ESRF
2009
Biochemical and Structural Analysis of Helix pomatia Agglutinin
2006
The crystal structure of cyclin A
1995 StandoutNobel
The Fucose-binding Lectin from Ralstonia solanacearum
2005
Design of Inhibitors of Glycogen Phosphorylase: A Study of .alpha.- and .beta.-C-Glucosides and 1-Thio-.beta.-D-glucose Compounds
1994
Ternary Complex Crystal Structures of Glycogen Phosphorylase with the Transition State Analogue Nojirimycin Tetrazole and Phosphate in the T and R States,
1996
Flash freezing of protein crystals: investigation of mosaic spread and diffraction limit with variation of cryoprotectant concentration
1994
Potent inhibition of glycogen phosphorylase by a spirohydantoin of glucopyranose: First pyranose analogues of hydantocidin
1995
Diamond: a multilayer and sagittally focusing crystal as optical elements on the ID14/Quadriga-3 beamline at ESRF
1998
The Rheological and Structural Properties of Fmoc-Peptide-Based Hydrogels: The Effect of Aromatic Molecular Architecture on Self-Assembly and Physical Characteristics
2012
Rankless by CCL
2026