Citation Impact
Citing Papers
IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma
2018
A Comprehensive Survey of Clonal Diversity Measures in Barrett's Esophagus as Biomarkers of Progression to Esophageal Adenocarcinoma
2010
Wild-Type KRAS Is Required for Panitumumab Efficacy in Patients With Metastatic Colorectal Cancer
2008 Standout
Immune Control of Tuberculosis by IFN-γ-Inducible LRG-47
2003 StandoutScience
Reciprocal Regulation of DUSP9 and DUSP16 Expression by HIF1 Controls ERK and p38 MAP Kinase Activity and Mediates Chemotherapy-Induced Breast Cancer Stem Cell Enrichment
2018 StandoutNobel
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Computationally designed sensors detect endogenous Ras activity and signaling effectors at subcellular resolution
2024 StandoutNobel
Thematic review series: Lipid Posttranslational Modifications. Farnesyl transferase inhibitors
2005
Head and neck squamous cell carcinoma
2020 Standout
Differential Membrane Localization of ERas and Rheb, Two Ras-related Proteins Involved in the Phosphatidylinositol 3-Kinase/mTOR Pathway
2005 StandoutNobel
EGFR Antagonists in Cancer Treatment
2008 Standout
MCP-1 deficiency reduces susceptibility to atherosclerosis in mice that overexpress human apolipoprotein B
1999
Management of borderline and locally advanced pancreatic cancer: Where do we stand?
2014
Patient-Derived Xenograft Models: An Emerging Platform for Translational Cancer Research
2014 Standout
Inflammation and Cancer: Triggers, Mechanisms, and Consequences
2019 Standout
Recurrent de novo point mutations in lamin A cause Hutchinson–Gilford progeria syndrome
2003 StandoutNature
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
2003 StandoutNatureNobel
Pancreatic cancer
2020 Standout
The biology and management of non-small cell lung cancer
2018 StandoutNature
The genetics of ageing
2010 StandoutNature
Therapeutic Strategies for Targeting Ras Proteins
2011
Disruption of the Mouse Rce1 Gene Results in Defective Ras Processing and Mislocalization of Ras within Cells
1999
Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future
2017 Standout
OPTIMA: a phase II dose and volume de-escalation trial for human papillomavirus-positive oropharyngeal cancer
2018
VEGF and angiogenesis in acute and chronic MOG(35–55) peptide induced EAE
2009
Pancreatic cancer
2016 Standout
Post-prenylation-processing enzymes as new targets in oncogenesis
2005
Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update
2015
Cancer stem cells revisited
2017 Standout
Ras history
2010
Lung cancer: current therapies and new targeted treatments
2016 Standout
Cancer genes and the pathways they control
2004 Standout
Upstream and downstream of mTOR
2004 Standout
Cell and molecular biology of the assembly and secretion of apolipoprotein B-containing lipoproteins by the liver
1999
Targeting Ras and Rho GTPases as opportunities for cancer therapeutics
2004
Role of Oxidative Modifications in Atherosclerosis
2004 Standout
Urinary Metabolomics for Noninvasive Detection of Borderline and Acute T Cell–Mediated Rejection in Children After Kidney Transplantation
2014
Farnesylation of Pex19p is not essential for peroxisome biogenesis in yeast and mammalian cells
2006
Targeting RAS signalling pathways in cancer therapy
2003 Standout
Angiotensin II promotes atherosclerotic lesions and aneurysms in apolipoprotein E–deficient mice
2000 Standout
Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer
2007 Standout
The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth
2023 Standout
Mechanisms of cutaneous toxicities to EGFR inhibitors
2006
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: a systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer
2008
Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer
2017 StandoutNature
Molecular Basis of the Interaction between Plasma Platelet-activating Factor Acetylhydrolase and Low Density Lipoprotein
1999
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
2015 StandoutNature
Targeted Inactivation of the Isoprenylcysteine Carboxyl Methyltransferase Gene Causes Mislocalization of K-Ras in Mammalian Cells
2000
Clonal evolution in cancer
2012 StandoutNature
let-7 Regulates Self Renewal and Tumorigenicity of Breast Cancer Cells
2007 Standout
Fusobacterium nucleatum Promotes Chemoresistance to Colorectal Cancer by Modulating Autophagy
2017 Standout
MetaboAnalyst 3.0—making metabolomics more meaningful
2015 Standout
Combined Serum Paraoxonase Knockout/Apolipoprotein E Knockout Mice Exhibit Increased Lipoprotein Oxidation and Atherosclerosis
2000 Standout
VEGF in Signaling and Disease: Beyond Discovery and Development
2019 Standout
Atherosclerosis
2001 Standout
Biomarkers for pancreatic cancer: promising new markers and options beyond CA 19-9
2013
Isoprenylcysteine Carboxyl Methyltransferase Deficiency in Mice
2001
Beyond EGFR and ALK inhibition: Unravelling and exploiting novel genetic alterations in advanced non small-cell lung cancer
2015
Molecular Basis for G Protein Control of the Prokaryotic ATP Sulfurylase
2006 StandoutNobel
Inactivation of Icmt inhibits transformation by oncogenic K-Ras and B-Raf
2004
Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
2009 Standout
The Many Roles of Chemokines and Chemokine Receptors in Inflammation
2006 Standout
Evolutionary Origins of the Mammalian ApolipoproteinB RNA Editing Enzyme, Apobec-1: Structural Homology Inferred from Analysis of a Cloned Chicken Small Intestinal Cytidine Deaminase
1998
Advanced Atherosclerotic Lesions in the Innominate Artery of the ApoE Knockout Mouse
2000
Small GTP-Binding Proteins
2001 Standout
Head and Neck Cancer
2020 Standout
The Posttranslational Processing of Prelamin A and Disease
2009
Identification of DNA cleavage- and recombination-specific hnRNP cofactors for activation-induced cytidine deaminase
2015 StandoutNobel
Neuropilin 1 deficiency on CD4+Foxp3+ regulatory T cells impairs mouse melanoma growth
2012 StandoutNobel
Targeting Ras signaling through inhibition of carboxyl methylation: An unexpected property of methotrexate
2003
A vesicle carrier that mediates peroxisome protein traffic from the endoplasmic reticulum
2010 StandoutNobel
Molecular Determinants of Regulated Exocytosis
2002 StandoutNobel
Concepts in Ras-directed therapy
1999
Click-Chemistry Based High Throughput Screening Platform for Modulators of Ras Palmitoylation
2017 StandoutNobel
PostprenylationCAAXProcessing Is Required for Proper Localization of Ras but Not Rho GTPases
2005
H-ras but Not K-ras Traffics to the Plasma Membrane through the Exocytic Pathway
2000
Resistance to Anti-Angiogenic Therapy in Cancer—Alterations to Anti-VEGF Pathway
2018
BindingDB Entry 2025: Characterization of the antitumor effects of the selective farnesyl protein transferase inhibitor R115777 in vivo and in vitro.
2007
Adjuvant Systemic Therapy and Adjuvant Radiation Therapy for Stage I to IIIA Completely Resected Non–Small-Cell Lung Cancers: American Society of Clinical Oncology/Cancer Care Ontario Clinical Practice Guideline Update
2017
Correlation between Development of Rash and Efficacy in Patients Treated with the Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Erlotinib in Two Large Phase III Studies
2007
Phospholipase A2Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention
2011 Standout
Inactivation of Icmt inhibits transformation by oncogenic K-Ras and B-Raf
2004
Targeting RAS Membrane Association: Back to the Future for Anti-RAS Drug Discovery?
2015
Vascular Calcification
2008 Standout
Structure of the Sec23p/24p and Sec13p/31p complexes of COPII
2001 StandoutNobel
Fighting cancer by disrupting C-terminal methylation of signaling proteins
2004
Zmpste24 deficiency in mice causes spontaneous bone fractures, muscle weakness, and a prelamin A processing defect
2002
Works of Edward Kim being referenced
Pilot Clinical Trial of Hedgehog Pathway Inhibitor GDC-0449 (Vismodegib) in Combination with Gemcitabine in Patients with Metastatic Pancreatic Adenocarcinoma
2014
Anti-DLL4 Has Broad Spectrum Activity in Pancreatic Cancer Dependent on Targeting DLL4-Notch Signaling in Both Tumor and Vasculature Cells
2012
The Notch Pathway Is Important in Maintaining the Cancer Stem Cell Population in Pancreatic Cancer
2014
Validation of a Molecular and Pathological Model for Five-Year Mortality Risk in Patients with Early Stage Lung Adenocarcinoma
2014
Genetically modified mice for the study of apolipoprotein B
1998
Role of intensity-modulated radiation therapy in gastrointestinal cancer
2009
Urinary Chemokines CXCL9 and CXCL10 Are Noninvasive Markers of Renal Allograft Rejection and BK Viral Infection
2011
Reduced-dose radiotherapy for human papillomavirus-associated squamous-cell carcinoma of the oropharynx: a single-arm, phase 2 study
2017
Managing Dermatologic Toxicities of Epidermal Growth Factor Receptor Inhibitors
2006
Phase II study of dovitinib in patients progressing on anti-vascular endothelial growth factor therapy
2016
Advances in pancreatic cancer
2011
Clinical and Biomarker Outcomes of the Phase II Vandetanib Study from the BATTLE Trial
2013
A multi‐institutional phase 2 study of neoadjuvant gemcitabine and oxaliplatin with radiation therapy in patients with pancreatic cancer
2013
Absence of the CAAX Endoprotease Rce1: Effects on Cell Growth and Transformation
2002
Podoplanin: A Novel Marker for Oral Cancer Risk in Patients With Oral Premalignancy
2008
Management of Rash and Other Toxicities in Patients Treated with Epidermal Growth Factor Receptor—Targeted Agents
2005
Phase I Study of the Farnesyltransferase Inhibitor BMS-214662 Given Weekly in Patients with Solid Tumors
2005
Cloning and Characterization of a Mammalian Prenyl Protein-specific Protease
1999