Citation Impact
Citing Papers
Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1
1996 StandoutNobel
Role of the CLOCK Protein in the Mammalian Circadian Mechanism
1998 StandoutScience
CYCLE Is a Second bHLH-PAS Clock Protein Essential for Circadian Rhythmicity and Transcription of Drosophila period and timeless
1998 StandoutNobel
Characterization of a Subset of the Basic-Helix-Loop-Helix-PAS Superfamily That Interacts with Components of the Dioxin Signaling Pathway
1997
Hypoxia-inducible factor 2α (HIF-2α) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension
2011 StandoutNobel
Molecular evolution of two vertebrate aryl hydrocarbon (dioxin) receptors (AHR1 and AHR2) and the PAS family
1997
The basic-helix–loop–helix-PAS orphan MOP3 forms transcriptionally active complexes with circadian and hypoxia factors
1998
DNA Binding Specificities and Pairing Rules of the Ah Receptor, ARNT, and SIM Proteins
1995
The DNA-damage response in human biology and disease
2009 StandoutNature
Hypoxia-inducible factors in the kidney
2006
The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins
2008 StandoutNature
Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA
1991 StandoutNature
Targeting HIF-1 for cancer therapy
2003 StandoutNobel
Microbial tryptophan catabolites in health and disease
2018 Standout
Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation
2006 StandoutNature
P450 Gene Induction by Structurally Diverse Xenochemicals: Central Role of Nuclear Receptors CAR, PXR, and PPAR
1999
Cell Proliferation in Carcinogenesis
1990 Science
Crystal Structure and Functional Analysis of the HERG Potassium Channel N Terminus
1998 StandoutNobel
An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor
2011 StandoutNature
Cardiac hypertrophy in Aryl hydrocarbon receptor null mice is correlated with elevated angiotensin II, endothelin-1, and mean arterial blood pressure
2003
A Mutant Drosophila Homolog of Mammalian Clock Disrupts Circadian Rhythms and Transcription of period and timeless
1998 StandoutNobel
Biochemical and molecular biological evidence for the presence of type II iodothyronine deiodinase in mouse mammary gland
2000
Environmental and chemical carcinogenesis
2004
Disruption of the Arnt gene in endothelial cells causes hepatic vascular defects and partial embryonic lethality in mice
2006
The aryl hydrocarbon receptor in immunity
2009
An Aryl Hydrocarbon Receptor Odyssey to the Shores of Toxicology: The Deichmann Lecture, International Congress of Toxicology-XI
2007
Type 2 Iodothyronine Deiodinase Transgene Expression in the Mouse Heart Causes Cardiac-Specific Thyrotoxicosis1
2001
Clustering of Hepatotoxins Based on Mechanism of Toxicity Using Gene Expression Profiles
2001
The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism
2000 Nature
Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
1990 StandoutNature
Human nutrition, the gut microbiome and the immune system
2011 StandoutNature
Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ
1998 StandoutNature
Isolation and Expression of cDNAs from Rainbow Trout (Oncorhynchus mykiss) That Encode Two Novel Basic Helix-Loop-Helix/PER-ARNT-SIM (bHLH/PAS) Proteins with Distinct Functions in the Presence of the Aryl Hydrocarbon Receptor
1996
Investigation of type I and type III iodothyronine deiodinases in rat tissues using N-bromoacetyl-iodothyronine affinity labels
1995
Topological Analysis of the Integral Membrane Protein, Type 1 Iodothyronine Deiodinase (D1)
1995
Type I Iodothyronine Deiodinase: Unexpected Complexities in a Simple Deiodination Reaction
1994
The Drosophila gene tailless is expressed at the embryonic termini and is a member of the steroid receptor superfamily
1990 StandoutNobel
PAS is a dimerization domain common to Drosophila Period and several transcription factors
1993 StandoutNatureNobel
Isolation and characterization of the 5â²-upstream and untranslated regions of the mouse type II iodothyronine deiodinase gene
2000
Structure of the Human Type I Iodothyronine 5′-Deiodinase Gene and Localization to Chromosome 1p32–p33
1997
Isolation of differentially expressed genes upon immunoglobulin class switching by a subtractive hybridization method using uracil DNA glycosylase
1998
Isolation and Characterization of the Mouse Gene for the Type 3 Iodothyronine Deiodinase1
1999
Dimerization, DNA Binding, and Transactivation Properties of Hypoxia-inducible Factor 1
1996 StandoutNobel
Role reversal: new insights from new ligands for the xenobiotic receptor CAR
2001
Localization of the Type 3 Iodothyronine Deiodinase (DIO3) Gene to Human Chromosome 14q32 and Mouse Chromosome 12F1
1998
Mismatch Repair Deficiency in Phenotypically Normal Human Cells
1995 StandoutScienceNobel
cDNA cloning and structure of mouse putative Ah receptor
1992
Classification of a large microarray data set: Algorithm comparison and analysis of drug signatures
2005
Inhibition of mitochondrial respiration by neutral, monocationic, and dicationic bis-pyridines related to the dopaminergic neurotoxin 1-methyl-4-phenylpyridinium cation (MPP+)
1991
Coordination of circadian timing in mammals
2002 StandoutNature
Transcriptional Activation by the Mouse Ah Receptor.
1995
Specific Expression of Activation-induced Cytidine Deaminase (AID), a Novel Member of the RNA-editing Deaminase Family in Germinal Center B Cells
1999 StandoutNobel
The Deiodinase Family of Selenoproteins
1997
Aryl hydrocarbon receptor inhibition downregulates the TGF-β/Smad pathway in human glioblastoma cells
2009
Peroxisome proliferator-binding protein: identification and partial characterization of nafenopin-, clofibric acid-, and ciprofibrate-binding proteins from rat liver.
1987
Digoxin inhibits development of hypoxic pulmonary hypertension in mice
2012 StandoutNobel
Isolation and Characterization of Revertants from Four Different Classes of Aryl Hydrocarbon Hydroxylase-Deficient Hepa-1 Mutants
1984
Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene.
1993 StandoutNobel
Identification of the Ah Receptor Nuclear Translocator Protein (Arnt) as a Component of the DNA Binding Form of the Ah Receptor
1992 Science
Structural and functional differences in the dio1 gene in mice with inherited type 1 deiodinase deficiency.
1995
A Gene Expression Signature that Predicts the Future Onset of Drug-Induced Renal Tubular Toxicity
2005
Inducible, receptor-dependent protein-DNA interactions at a dioxin-responsive transcriptional enhancer.
1988
Nutritional and Hormonal Regulation of Thyroid Hormone Deiodinases
1995
Activation of the Aryl Hydrocarbon Receptor by Structurally Diverse Exogenous and Endogenous Chemicals
2003
Circadian oscillations in period gene mRNA levels are transcriptionally regulated.
1992 StandoutNobel
Biochemistry, Cellular and Molecular Biology, and Physiological Roles of the Iodothyronine Selenodeiodinases
2002 Standout
Nuclear Receptors and Lipid Physiology: Opening the X-Files
2001 StandoutScience
Novel cysteine-rich motif and homeodomain in the product of the Caenorhabditis elegans cell lineage gene lin-II
1990 StandoutNatureNobel
PER Protein Interactions and Temperature Compensation of a Circadian Clock in Drosophila
1995 StandoutScienceNobel
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.
1995 StandoutNobel
The Steroid and Thyroid Hormone Receptor Superfamily
1988 StandoutScience
Inactivation of the PBRM1 tumor suppressor gene amplifies the HIF-response in VHL −/− clear cell renal carcinoma
2017 StandoutNobel
Abnormal Vascular Function and Hypertension in Mice Deficient in Estrogen Receptor β
2002 StandoutScienceNobel
Prooxidant States and Tumor Promotion
1985 StandoutScience
ExBox: A Polycyclic Aromatic Hydrocarbon Scavenger
2012 StandoutNobel
In vitro analysis of Ah receptor domains involved in ligand-activated DNA recognition.
1993
Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factor.
1992
The Galvanization of Biology: A Growing Appreciation for the Roles of Zinc
1996 StandoutScience
Regulating the regulator: Factors that control levels and activity of the aryl hydrocarbon receptor
2006
Plasma Insulin-Like Growth Factor-I and Prostate Cancer Risk: A Prospective Study
1998 StandoutScience
Transcriptional activation function of the mouse Ah receptor nuclear translocator.
1994
AH RECEPTOR SIGNALING PATHWAYS
1996
Mechanisms of Estrogen Action
2001 Standout
A constitutively active dioxin/aryl hydrocarbon receptor induces stomach tumors
2002
Regulation of cytochrome P1-450 gene transcription by 2,3,7, 8-tetrachlorodibenzo-p-dioxin in wild type and variant mouse hepatoma cells.
1984
Distinct Tissue-Specific Roles for Thyroid Hormone Receptors β and α1 in Regulation of Type 1 Deiodinase Expression
2001
The stages of initiation and promotion in hepatocarcinogenesis
1980
On the biochemical mechanism of tumorigenesis in mouse skin
1977
Tumor initiators and promoters in the induction of Epstein—Barr virus
1979 StandoutNobel
Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth
1997 StandoutNobel
Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins
1989 StandoutScience
Mechanism of Action of a Repressor of Dioxin-Dependent Induction of Cyplal Gene Transcription
1992
Characterization of a murine Ahr null allele: involvement of the Ah receptor in hepatic growth and development.
1996
Cloning of a Factor Required for Activity of the Ah (Dioxin) Receptor
1991 Science
Protein-DNA interactions at a dioxin-responsive enhancer. Analysis of six bona fide DNA-binding sites for the liganded Ah receptor.
1993
Cancer risk assessment, indicators, and guidelines for polycyclic aromatic hydrocarbons in the ambient air.
2002
Quantitative evaluation of the promotion by 2,3,7,8-tetrachlorodibenzo-p-dioxin of hepatocarcinogenesis from diethylnitrosamine.
1980
Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue
2016 StandoutNobel
A Macrophage Factor Inhibits Adipocyte Gene Expression: An in Vitro Model of Cachexia
1985 StandoutScienceNobel
Renal Cyst Development in Mice with Conditional Inactivation of the von Hippel-Lindau Tumor Suppressor
2006
Mechanically induced intramolecular electron transfer in a mixed-valence molecular shuttle
2012 StandoutNobel
A Transmembrane Intracellular Estrogen Receptor Mediates Rapid Cell Signaling
2005 StandoutScience
Activation of the Estrogen Receptor Through Phosphorylation by Mitogen-Activated Protein Kinase
1995 StandoutScience
Differential regulation of mammalian Period genes and circadian rhythmicity by cryptochromes 1 and 2
1999 StandoutNobel
The Search for Endogenous Activators of the Aryl Hydrocarbon Receptor
2007
Effects of Selenium Deficiency on Tissue Selenium Content, Deiodinase Activity, and Thyroid Hormone Economy in the Rat during Development*
2000
The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease
2006 StandoutScience
Hypoxia-inducible factor 1 transcriptional activity in endothelial cells is required for acute phase cardioprotection induced by ischemic preconditioning
2012 StandoutNobel
Estrogen inhibits the vascular injury response in estrogen receptor β-deficient female mice
1999 StandoutNobel
cDNA Cloning and Tissue-Specific Expression of a Novel Basic Helix-Loop-Helix/PAS Factor (Arnt2) with Close Sequence Similarity to the Aryl Hydrocarbon Receptor Nuclear Translocator (Arnt)
1996
Detection of a nafenopin-binding protein in rat liver cytosol associated with the induction of peroxisome proliferation by hypolipidemic compounds
1983
Works of Edward Glover being referenced
Gestational exposure of Ahr and Arnt hypomorphs to dioxin rescues vascular development
2004
Chlorinated Biphenyl Induction of Aryl Hydrocarbon Hydroxylase Activity: a Study of the Structure-Activity Relationship
1977
1,4-Bis[2-(3,5-Dichloropyridyloxy)]Benzene, a Potent Phenobarbital-Like Inducer of Microsomal Monooxygenase Activity
1980
Comparison of 2,3,7,8-Tetrachlorodibenzo-p-dioxin, a Potent Inducer of Aryl Hydrocarbon Hydroxylase, with 3-Methylcholanthrene
1974
Structure-activity relationship of bispyridyloxybenzene for induction of mouse hepatic aminopyrine N-demethylase activity. Chemical, biological, and X-ray crystallographic studies.
1985
Species Differences in Responsiveness to 1,4-Bis[2-(3,5-dichloropyridyloxy)]-benzene, a Potent Phenobarbital-Like Inducer of Microsomal Monooxygenase Activity
1981
Genetic Expression of Aryl Hydrocarbon Hydroxylase by 2,3,7,8-Tetrachlorodibenzo-p-dioxin: Evidence for a Receptor Mutation in Genetically Non-responsive Mice
1975
Resistance to 2,3,7,8-Tetrachlorodibenzo-p-dioxin Toxicity and Abnormal Liver Development in Mice Carrying a Mutation in the Nuclear Localization Sequence of the Aryl Hydrocarbon Receptor
2003
Identification of toxicologically predictive gene sets using cDNA microarrays
2001
The Aryl Hydrocarbon Receptor Signaling Pathway Is Modified through Interactions with a Kelch Protein
2006
Aryl hydrocarbon receptor response to indigoids in vitro and in vivo
2004
Physiological and genetic analyses of inbred mouse strains with a type I iodothyronine 5' deiodinase deficiency.
1993
The Aryl Hydrocarbon Receptor Is Required for Developmental Closure of the Ductus Venosus in the Neonatal Mouse
2004
Patent Ductus Venosus and Dioxin Resistance in Mice Harboring a Hypomorphic Arnt Allele
2004
A Maternal Ahr Null Genotype Sensitizes Embryos to Chemical Teratogenesis
2004
Analysis of the four alleles of the murine aryl hydrocarbon receptor.
1994
Studies on the mechanism of action of halogenated aromatic hydrocarbons.
1985
2,3,7,8,-Tetrachlorodibenzo-p-dioxin: segregation of toxocity with the Ah locus.
1980
An estimate of the maximum in vivo covalent binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin to rat liver protein, ribosomal RNA, and DNA.
1979
Characterization of polyclonal antibodies to the Ah receptor prepared by immunization with a synthetic peptide hapten.
1991
Stereospecific, high affinity binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin by hepatic cytosol. Evidence that the binding species is receptor for induction of aryl hydrocarbon hydroxylase.
1976
Purification and N-terminal amino acid sequence of the Ah receptor from the C57BL/6J mouse.
1991
Tumour promotion by TCDD in skin of HRS/J hairless mice
1982 Nature
The murine Ah locus: a new allele and mapping to chromosome 12.
1987
Variation in the molecular mass of the Ah receptor among vertebrate species and strains of rats
1987
Aryl hydrocarbon receptor-dependent liver development and hepatotoxicity are mediated by different cell types
2005
Photoaffinity labeling of the Ah receptor.
1986
2,3,7,8-Tetrachlorodibenzo-p-dioxin: A Potent Inducer of δ-Aminolevulinic Acid Synthetase
1973 Science
Characterization and strain distribution pattern of the murine Ah receptor specified by the Ahd and Ahb-3 alleles.
1990
Chlorinated dibenzo-p-dioxins: potent inducers of delta-aminolevulinic acid synthetase and aryl hydrocarbon hydroxylase. II. A study of the structure-activity relationship.
1973
Genetic Expression of Aryl Hydrocarbon Hydroxylase Activity
1974
Portosystemic shunting and persistent fetal vascular structures in aryl hydrocarbon receptor-deficient mice
2000