Standout Papers
Citation Impact
Citing Papers
Variation in Transcription Factor Binding Among Humans
2010 Science
ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation
2009 StandoutScience
Inhibition of vascular endothelial growth factor with a sequence-specific hypoxia response element antagonist
2004 StandoutNobel
MicroRNA-155 is induced during the macrophage inflammatory response
2007 StandoutNobel
Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions
2009 StandoutScience
The Type I Interferon Signaling Pathway Is a Target for Glucocorticoid Inhibition
2010
Induction of interferon-stimulated gene expression and antiviral responses require protein deacetylase activity
2004 StandoutNobel
Stat5a Serine Phosphorylation
2000
Differential expression analysis for sequence count data
2010 Standout
JAK-STAT Signaling: From Interferons to Cytokines
2007
The Interleukin-4 Enhancer CNS-2 Is Regulated by Notch Signals and Controls Initial Expression in NKT Cells and Memory-Type CD4 T Cells
2006 StandoutNobel
The LxxLL motif: a multifunctional binding sequence in transcriptional regulation
2004
Acromegaly
2006 Standout
Endocrine regulation of heat shock protein mRNA levels in long-lived dwarf mice
2009
Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study
2020 Standout
Mechanisms and Functional Implications of Adult Neurogenesis
2008 Standout
Histone deacetylases and cancer
2007
Acetylation-Dependent Signal Transduction for Type I Interferon Receptor
2007
X-ray structure of the orphan nuclear receptor RORbeta ligand-binding domain in the active conformation
2001
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
2002 StandoutNature
Normal-appearing white matter in multiple sclerosis is in a subtle balance between inflammation and neuroprotection
2007
Transcription factors as targets for cancer therapy
2002
Update on glucocorticoid action and resistance
2006
The IL-7 Receptor Controls the Accessibility of the TCRγ Locus by Stat5 and Histone Acetylation
2001 StandoutNobel
Stat3 as an Oncogene
1999 Standout
Linked T Cell Receptor and Cytokine Signaling Govern the Development of the Regulatory T Cell Repertoire
2008
The Human Transcription Factors
2018 Standout
A microRNA program in the C. elegans hypodermis couples to intestinal mTORC2/PQM-1 signaling to modulate fat transport
2016 StandoutNobel
Characterization of Two Mosquito STATs, AaSTAT and CtSTAT
2004
The Epigenomics of Cancer
2007 Standout
Signal integration between IFNγ and TLR signalling pathways in macrophages
2006
Induction of Germline Transcription in the TCRγ Locus by Stat5
1999 StandoutNobel
Mapping and analysis of chromatin state dynamics in nine human cell types
2011 StandoutNature
Serine phosphorylation of STATs
2000
Epigenetics in Cancer
2008 Standout
Multiple sclerosis
2008 Standout
Anticancer activities of histone deacetylase inhibitors
2006 Standout
Regulation of Liver Inflammatory Injury by Signal Transducer and Activator of Transcription-6
2000
Glutamate neurotoxicity and diseases of the nervous system
1988 Standout
Functional Interaction of STAT3 Transcription Factor with the Coactivator NcoA/SRC1a
2002
Expression and Function of Members of a Divergent Nuclear Receptor Family in Caenorhabditis elegans
1999
Interaction of Steroid Hormone Receptors with the Transcription Initiation Complex
1996
The Biological Functions of the Versatile Transcription Factors STAT3 and STAT5 and New Strategies for their Targeted Inhibition
2006
Functional interaction of STAT5 and nuclear receptor co-repressor SMRT: implications in negative regulation of STAT5-dependent transcription
2001
Exacerbated Innate Host Response to SARS-CoV in Aged Non-Human Primates
2010
Functional Association of Nmi with Stat5 and Stat1 in IL-2- and IFN γ-Mediated Signaling
1999
STAT1 as a key modulator of cell death
2006
BMP Induction of Id Proteins Suppresses Differentiation and Sustains Embryonic Stem Cell Self-Renewal in Collaboration with STAT3
2003 Standout
Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders
2005 Standout
A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations
2010 Standout
Region 752–761 of STAT3 is critical for SRC-1 recruitment and Ser727 phosphorylation
2004
IFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage
2013 StandoutNobel
Distinct Foxp3 enhancer elements coordinate development, maintenance, and function of regulatory T cells
2021 StandoutNobel
Molecular basis of agonism and antagonism in the oestrogen receptor
1997 StandoutNature
Prediction of the structure of human Janus kinase 2 (JAK2) comprising the two carboxy-terminal domains reveals a mechanism for autoregulation
2001
Stat Protein Transactivation Domains Recruit p300/CBP through Widely Divergent Sequences
1999
Transcription factor networks in trophoblast development
2022
The Coactivator of Transcription CREB-binding Protein Interacts Preferentially with the Glycosylated Form of Stat5
2004
Cytokine Signaling in 2002
2002 Standout
The Hallmarks of Aging
2013 Standout
The NS5A Protein of Hepatitis C Virus Is a Zinc Metalloprotein
2004 StandoutNobel
Erythropoietin Can Induce the Expression of Bcl-xLthrough Stat5 in Erythropoietin-dependent Progenitor Cell Lines
1999
The Jak-STAT signaling pathway is required but not sufficient for the antiviral response of drosophila
2005 StandoutNobel
Dual modes of CLOCK:BMAL1 inhibition mediated by Cryptochrome and Period proteins in the mammalian circadian clock
2014 StandoutNobel
Signal Transducer and Activator of Transcription‐3, Inflammation, and Cancer
2009 Standout
Lysine Acetylation: Codified Crosstalk with Other Posttranslational Modifications
2008
A light-sensing knot revealed by the structure of the chromophore-binding domain of phytochrome
2005 Nature
A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
2005 StandoutNature
The Jak-STAT pathway
2000
Notch1 and Notch3 Instructively Restrict bFGF-Responsive Multipotent Neural Progenitor Cells to an Astroglial Fate
2001 StandoutNobel
Integrating cell-signalling pathways with NF-κB and IKK function
2006 Standout
Repurposed Antiviral Drugs for Covid-19 — Interim WHO Solidarity Trial Results
2020 Standout
Chemical Topology: Complex Molecular Knots, Links, and Entanglements
2011 StandoutNobel
Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy
2023 StandoutNobel
The Transcriptional Integrator CREB-Binding Protein Mediates Positive Cross Talk between Nuclear Hormone Receptors and the Hematopoietic bZip Protein p45/NF-E2
1997
Orphan nuclear receptor TLX recruits histone deacetylases to repress transcription and regulate neural stem cell proliferation
2007
Principles of interleukin (IL)-6-type cytokine signalling and its regulation
2003 Standout
DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells
2000 StandoutNobel
Nuclear Receptors and Lipid Physiology: Opening the X-Files
2001 StandoutScience
An Intron Transcriptional Enhancer Element Regulates IL-4 Gene Locus Accessibility in Mast Cells
2000
Signal transducers and activators of transcription 3 (STAT3) inhibits transcription of the inducible nitric oxide synthase gene by interacting with nuclear factor κB
2002
Membrane proteomics of phagosomes suggests a connection to autophagy
2008 StandoutNobel
Emerging Models for the Molecular Basis of Mammalian Circadian Timing
2014
The hepatitis C virus NS5A protein binds to members of the Src family of tyrosine kinases and regulates kinase activity
2004
2-Aroylindoles and 2-Aroylbenzofurans with N-Hydroxyacrylamide Substructures as a Novel Series of Rationally Designed Histone Deacetylase Inhibitors
2007
Metal-Catalyzed Decarboxylative C–H Functionalization
2017 Standout
Uses for JNK: the Many and Varied Substrates of the c-Jun N-Terminal Kinases
2006
Interferon-Stimulated Genes: A Complex Web of Host Defenses
2014 StandoutNobel
The Two Faces of Interferon-γ in Cancer
2011
Maximal Induction of a Subset of Interferon Target Genes Requires the Chromatin-Remodeling Activity of the BAF Complex
2002
Epigenetic conversion of conventional T cells into regulatory T cells by CD28 signal deprivation
2020 StandoutNobel
Estrogen inhibits GH signaling by suppressing GH-induced JAK2 phosphorylation, an effect mediated by SOCS-2
2003
Erythropoietin crosses the blood–brain barrier to protect against experimental brain injury
2000 Standout
Synergistic Signaling in Fetal Brain by STAT3-Smad1 Complex Bridged by p300
1999 Science
Stat5b Inhibits NFκB-Mediated Signaling
2000
Metabolic labeling enables selective photocrosslinking of O-GlcNAc-modified proteins to their binding partners
2012 StandoutNobel
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Works of Edith Pfitzner being referenced
Cytokine Receptor-independent, Constitutively Active Variants of STAT5
1997
Heat shock protein-90-alpha, a prolactin-STAT5 target gene identified in breast cancer cells, is involved in apoptosis regulation
2008
Acetylation of Stat1 modulates NF-κB activity
2006
Interactions in the transcriptional regulation exerted by Stat5 and by members of the steroid hormone receptor family
1999
Leukemia inhibitory factor triggers activation of signal transducer and activator of transcription 3, proliferation, invasiveness, and altered protease expression in choriocarcinoma cells
2005
Coactivators in Gene Regulation by STAT5
2005
Transcriptional Activation by STAT6 Requires the Direct Interaction with NCoA-1
2001
Structure of the NCoA-1/SRC-1 PAS-B Domain Bound to the LXXLL Motif of the STAT6 Transactivation Domain
2004 StandoutNobel
p300/CBP is required for transcriptional induction by interleukin-4 and interacts with Stat6
1999
An LXXLL Motif in the Transactivation Domain of STAT6 Mediates Recruitment of NCoA-1/SRC-1
2002
Regulation of the trans-activation potential of STAT5 through its DNA-binding activity and interactions with heterologous transcription factors
2000
The Role of STATs in Inflammation and Inflammatory Diseases
2004
p300/CREB-Binding Protein Enhances the Prolactin-Mediated Transcriptional Induction through Direct Interaction with the Transactivation Domain of Stat5, but Does Not Participate in the Stat5-Mediated Suppression of the Glucocorticoid Response
1998
p300/CREB-Binding Protein Enhances the Prolactin-Mediated Transcriptional Induction through Direct Interaction with the Transactivation Domain of Stat5, but Does Not Participate in the Stat5-Mediated Suppression of the Glucocorticoid Response
1998
Functional antagonism between the retinoic acid receptor and the viral transactivator BZLF1 is mediated by protein-protein interactions.
1995
Recombinant activation domains of virion protein 16 and human estrogen receptor generate transcriptional interference in vitro by distinct mechanisms.
1993