Citation Impact
Citing Papers
EF-P Is Essential for Rapid Synthesis of Proteins Containing Consecutive Proline Residues
2012 Science
Formation of the First Peptide Bond: The Structure of EF-P Bound to the 70 S Ribosome
2009 StandoutScienceNobel
Nmd3 is a structural mimic of eIF 5A, and activates the cp GTP ase Lsg1 during 60S ribosome biogenesis
2017 StandoutNobel
Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence
2019
Tuning the Transcriptional Response to Hypoxia by Inhibiting Hypoxia-inducible Factor (HIF) Prolyl and Asparaginyl Hydroxylases
2016 StandoutNobel
Interactions of elongation factor EF‐P with the Escherichia coli ribosome
2008
Demethylation of 3-Methylthymine in DNA by Bacterial and Human DNA Dioxygenases
2004 StandoutNobel
A Family of Basic Amino Acid Transporters of the Vacuolar Membrane from Saccharomyces cerevisiae
2004 StandoutNobel
Structure of the hypusinylated eukaryotic translation factor eIF-5A bound to the ribosome
2015
Hypusine-containing protein eIF5A promotes translation elongation
2009 Nature
Physiological and biochemical aspects of hydroxylations and demethylations catalyzed by human 2-oxoglutarate oxygenases
2010
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Nuclear RNA export
1998 StandoutNobel
Inhibition of 2-oxoglutarate dependent oxygenases
2011
Computational Enzyme Design
2013 StandoutNobel
Insulin-promoter-factor 1 is required for pancreas development in mice
1994 StandoutNature
Hallmarks of aging: An expanding universe
2023 Standout
eIF5A hypusination, boosted by dietary spermidine, protects from premature brain aging and mitochondrial dysfunction
2021
Expanding the Enzyme Universe: Accessing Non‐Natural Reactions by Mechanism‐Guided Directed Evolution
2015 StandoutNobel
Functions of Polyamines in Mammals
2016
Translational control in cancer
2010
Two RNA-binding motifs in eIF3 direct HCV IRES-dependent translation
2013 StandoutNobel
What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer
2013 StandoutNobel
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
The yeast nucleoporin Rip1p contributes to multiple export pathways with no essential role for its FG-repeat region
1997 StandoutNobel
Polyamines and Their Metabolites as Diagnostic Markers of Human Diseases
2013
TET enzymes, TDG and the dynamics of DNA demethylation
2013 StandoutNature
Horizontal gene transfer and archaeal origin of deoxyhypusine synthase homologous genes in bacteria
2004
Tandem affinity purification revealed the hypusine‐dependent binding of eukaryotic initiation factor 5A to the translating 80S ribosomal complex
2005
eIF5A Promotes Translation of Polyproline Motifs
2013
Crystal Structure of the Non-heme Iron Dioxygenase PtlH in Pentalenolactone Biosynthesis
2007 StandoutNobel
The NMR structure of the activation domain isolated from porcine procarboxypeptidase B.
1991 StandoutNobel
Dynamic Combinatorial Chemistry Employing Boronic Acids/Boronate Esters Leads to Potent Oxygenase Inhibitors
2012 StandoutNobel
Asparagine and Aspartate Hydroxylation of the Cytoskeletal Ankyrin Family Is Catalyzed by Factor-inhibiting Hypoxia-inducible Factor
2010 StandoutNobel
Emerging Concepts in Targeting the Polyamine Metabolic Pathway in Epithelial Cancer Chemoprevention and Chemotherapy
2006
Fe(II)/α-Ketoglutarate-Dependent Hydroxylases and Related Enzymes
2004
N1-Aminopropylagmatine, a New Polyamine Produced as a Key Intermediate in Polyamine Biosynthesis of an Extreme Thermophile, Thermus thermophilus
2005
Is there a role for eIF5A in translation?
2007
THE HIV-1 REV PROTEIN
1998
Iron-Catalyzed Reactions in Organic Synthesis
2004 Standout
Iron Catalysis in Organic Synthesis
2015 Standout
Dynamic model of globular protein conformations based on NMR studies in solution
1978 StandoutNatureNobel
Ab Initio Evaluation of the Potential Surface for General Base- Catalyzed Methanolysis of Formamide: A Reference Solution Reaction for Studies of Serine Proteases
2000 StandoutNobel
3d Transition Metals for C–H Activation
2018 Standout
Evidence for Tyrosine at the Active Center of Bovine Carboxypeptidase B
1966
Preparation and Characterization of the Active Derivative of Bovine Trypsin‐Kallikrein Inhibitor (Kunitz) with the Reactive Site Lysine‐15 – Alanine‐16 Hydrolyzed
1976
Comparison of the Multiple Forms of Bovine Pancreatic Deoxyribonuclease
1970 StandoutNobel
The Enzymatic Synthesis of S-Adenosyl-l-homocysteine from Adenosine and Homocysteine
1959
Mechanism and regulation of eukaryotic protein synthesis
1992
The Porcine Pancreatic Carboxypeptidase A System
1963
Studies of Carcinogenesis by Avian Sarcoma Viruses
1966 StandoutNobel
Recent Advances in Transition Metal Catalyzed Oxidation of Organic Substrates with Molecular Oxygen
2005 Standout
Evolutionary Conservation of Reactions in Translation
2002
Structural and Functional Aspects of Metal Sites in Biology
1996 Standout
Crystal structure of elongation factor P from Thermus thermophilus HB8
2004
Carboxypeptidase in blood and other fluids—I.
1964
Spermidine in health and disease
2018 StandoutScience
Dioxygen Activation at Mononuclear Nonheme Iron Active Sites: Enzymes, Models, and Intermediates
2004 Standout
A novel translational repressor mRNA is edited extensively in livers containing tumors caused by the transgene expression of the apoB mRNA-editing enzyme.
1997 StandoutNobel
Eukaryotic initiation factor 5A is a cellular target of the human immunodeficiency virus type 1 Rev activation domain mediating trans-activation.
1993
Translation initiation factor 5A and its hypusine modification are essential for cell viability in the yeast Saccharomyces cerevisiae.
1991
Structure of carboxypeptidase B at 2.8 Å resolution
1976
THE DEVELOPMENT OF THE DORSAL AND VENTRAL MAMMALIAN PANCREAS IN VIVO AND IN VITRO
1970
Hydroxylation of the eukaryotic ribosomal decoding center affects translational accuracy
2014 StandoutNobel
Yeast KEX1 gene encodes a putative protease with a carboxypeptidase B-like function involved in killer toxin and α-factor precursor processing
1987
Affinity Labeling of the Active Site of Staphylococcal Nuclease
1969 StandoutNobel
Clathrin: A Role in the Intracellular Retention of a Golgi Membrane Protein
1989 StandoutScienceNobel
Studies on the Guinea Pig Pancreas
1974 StandoutNobel
Identification of a New Endogenous Metabolite and the Characterization of Its Protein Interactions through an Immobilization Approach
2008 StandoutNobel
The Isolation of Porcine Ribonuclease, a Glycoprotein, from Pancreatic Juice
1968
Sulfuration of O-acetylhomoserine and O-acetylserine by two enzyme fractions from spinach
1968
Glutamic Dehydrogenase
1959
Computer simulations of enzyme catalysis: Finding out what has been optimized by evolution
1998 StandoutNobel
Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth
2014 StandoutNobel
Similarities Between the Conformation of Arsanilazotyrosine 248 of Carboxypeptidase A α in the Crystalline State and in Solution
1972 StandoutNobel
Enzymatic synthesis of cysteine and S-methylcysteine in plant extracts
1968
Prepro-alpha-factor has a cleavable signal sequence.
1988 StandoutNobel
Kinetic Studies on Tyrosine-α-ketoglutarate Transaminase
1963
Mechanism of Aconitase Action
1967 StandoutNobel
Functional reconstitution of human eukaryotic translation initiation factor 3 (eIF3)
2011 StandoutNobel
Direct C−H Transformation via Iron Catalysis
2010 Standout
Fate of Angiotensin I in the Circulation
1968 StandoutNatureNobel
Rates of Uncatalyzed Peptide Bond Hydrolysis in Neutral Solution and the Transition State Affinities of Proteases
1996
OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation
2014 StandoutNobel
Modulation of cyclic AMP metabolism by S-adenosylhomocysteine and S-3-deazaadenosylhomocysteine in mouse lymphocytes.
1980 StandoutNobel
Simulating the pulling of stalled elongated peptide from the ribosome by the translocon
2013 StandoutNobel
Translation Initiation Factor 5A and Its Hypusine Modification Are Essential for Cell Viability in the Yeast Saccharomyces cerevisiae
1991
Structure and Chemistry of Cytochrome P450
2005 Standout
Works of Edith C. Wolff being referenced
Hypusine, a polyamine-derived amino acid critical for eukaryotic translation
2018
Enzyme-Substrate Intermediate Formation at Lysine 329 of Human Deoxyhypusine Synthase
1997
Posttranslational synthesis of hypusine: evolutionary progression and specificity of the hypusine modification
2007
The antifungal drug ciclopirox inhibits deoxyhypusine and proline hydroxylation, endothelial cell growth and angiogenesis in vitro
2002
Deoxyhypusine Synthase from Rat Testis: Purification and Characterization
1995
Eukaryotic initiation factor 5A-1 (eIF5A-1) as a diagnostic marker for aberrant proliferation in intraepithelial neoplasia of the vulva
2004
Identification and characterization of eukaryotic initiation factor 5A‐2
2003
Is hypusine essential for eukaryotic cell proliferation?
1993
Reversal of the Deoxyhypusine Synthesis Reaction
2003
eIF5A isoforms and cancer: two brothers for two functions?
2011
The Kinetics of Carboxypeptidase B Activity
1962
Two isoforms of eIF-5A in chick embryo. Isolation, activity, and comparison of sequences of the hypusine-containing proteins.
1992
Features of the spermidine-binding site of deoxyhypusine synthase as derived from inhibition studies. Effective inhibition by bis- and mono-guanylated diamines and polyamines
1993
The effect of thyroxine on isolated dehydrogenases
1957
Comparison of the activities of variant forms of eIF-4D. The requirement for hypusine or deoxyhypusine
1991
Antiproliferative effects of inhibitors of deoxyhypusine synthase. Inhibition of growth of Chinese hamster ovary cells by guanyl diamines.
1994
Cell-free synthesis of deoxyhypusine. Separation of protein substrate and enzyme and identification of 1,3-diaminopropane as a product of spermidine cleavage.
1988
The Kinetics of Carboxypeptidase B Activity
1962
The Kinetics of Carboxypeptidase B Activity
1962
Hypusine: its post-translational formation in eukaryotic initiation factor 5A and its potential role in cellular regulation.
1993
Molecular cloning, expression, and structural prediction of deoxyhypusine hydroxylase: A HEAT-repeat-containing metalloenzyme
2005
ENZYMATIC SYNTHESIS OF S-METHYLCYSTEINE
1956
Cleavage of spermidine as the first step in deoxyhypusine synthesis. The role of NAD.
1990
Cloning and expression of human deoxyhypusine synthase cDNA. Structure-function studies with the recombinant enzyme and mutant proteins.
1995
Complex formation between deoxyhypusine synthase and its protein substrate, the eukaryotic translation initiation factor 5A (eIF5A) precursor
1999