Citation Impact
Citing Papers
Enrichment of a Population of Mammary Gland Cells that Form Mammospheres and Have In vivo Repopulating Activity
2007
Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin
2007
The Dual Role of TGFβ in Human Cancer: From Tumor Suppression to Cancer Metastasis
2012
Functional Interaction between SEL-10, an F-box Protein, and the Nuclear Form of Activated Notch1 Receptor
2001 StandoutNobel
Epithelial-Mesenchymal Transition in Cancer: Parallels Between Normal Development and Tumor Progression
2010
Hallmarks of Cancer: The Next Generation
2011 Standout
Translation Initiation Factor eIF4G-1 Binds to eIF3 through the eIF3e Subunit
2006
Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m 6 A-demethylation of NANOG mRNA
2016 StandoutNobel
Mammary epithelial stem cells: transplantation and self‐renewal analysis
2003
In search of the tumour-suppressor functions of BRCA1 and BRCA2
2000 Nature
Mechanism of activation of the TGF-β receptor
1994 StandoutNature
Human Mammary Luminal Epithelial Cells Contain Progenitors to Myoepithelial Cells
1999
Stromal fibroblasts in cancer initiation and progression
2004 StandoutNature
Notch signaling is required for normal prostatic epithelial cell proliferation and differentiation
2005
Transgenic Mice Expressing a Dominant-Negative Mutant Type II Transforming Growth Factor-β Receptor Exhibit Impaired Mammary Development and Enhanced Mammary Tumor Formation
2003
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
2003 StandoutNobel
Mammary epithelial stem cells
2001
Patterns and Emerging Mechanisms of the Angiogenic Switch during Tumorigenesis
1996 Standout
Epigenetic regulation of aging stem cells
2011
Mechanisms of TGF-β Signaling from Cell Membrane to the Nucleus
2003 Standout
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Modulation of Notch Signaling Elicits Signature Tumors and Inhibits Hras1-Induced Oncogenesis in the Mouse Mammary Epithelium
2004
Cellular expression of estrogen and progesterone receptors in mammary glands: regulation by hormones, development and aging
2002
TGF-beta receptor-activated p38 MAP kinase mediates Smad-independent TGF-beta responses
2002
TGF-β signalling from cell membrane to nucleus through SMAD proteins
1997 StandoutNature
Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
2015 StandoutNature
Smad-dependent and Smad-independent pathways in TGF-β family signalling
2003 StandoutNature
The Hedgehog and Wnt signalling pathways in cancer
2001 StandoutNature
Wnt Proteins Are Self-Renewal Factors for Mammary Stem Cells and Promote Their Long-Term Expansion in Culture
2010
The mammary pathology of genetically engineered mice: the consensus report and recommendations from the Annapolis meeting
2000
Stem cells find their niche
2001 StandoutNature
TGFβ: the molecular Jekyll and Hyde of cancer
2006
Recent advances in cancer stem cells
2008
Translational control in cancer
2010
Models, mechanisms and clinical evidence for cancer dormancy
2007
Developmental Stage and Time Dictate the Fate of Wnt/β-Catenin-Responsive Stem Cells in the Mammary Gland
2012
Two RNA-binding motifs in eIF3 direct HCV IRES-dependent translation
2013 StandoutNobel
Wnt/β-Catenin Signaling and Disease
2012 Standout
The TGF-β family and its composite receptors
1994
Common Adult Stem Cells in the Human Breast Give Rise to Glandular and Myoepithelial Cell Lineages: A New Cell Biological Concept
2002
Modulation of Notch signaling by mastermind-like (MAML) transcriptional co-activators and their involvement in tumorigenesis
2004
Notch Signaling in Vertebrate Development and Disease
1997
Structure of mammalian eIF3 in the context of the 43S preinitiation complex
2015 StandoutNatureNobel
Stat5a is mandatory for adult mammary gland development and lactogenesis.
1997
Identification and expansion of human colon-cancer-initiating cells
2006 StandoutNature
Genome maintenance mechanisms for preventing cancer
2001 StandoutNature
Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy
2017 Standout
Asparaginyl Hydroxylation of the Notch Ankyrin Repeat Domain by Factor Inhibiting Hypoxia-inducible Factor
2007 StandoutNobel
Slug and Sox9 Cooperatively Determine the Mammary Stem Cell State
2012
Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids
2018 StandoutNobel
Sca-1pos Cells in the Mouse Mammary Gland Represent an Enriched Progenitor Cell Population
2002
Experimental mammary epithelial morphogenesis in anin vivo model: Evidence for distinct cellular progenitors of the ductal and lobular phenotype
1996
Generation of a functional mammary gland from a single stem cell
2006 StandoutNature
Characterization of bipotent mammary epithelial progenitor cells in normal adult human breast tissue
2001
Stem cells in normal breast development and breast cancer
2003
Purification and unique properties of mammary epithelial stem cells
2006 Nature
Jak2 Is an Essential Tyrosine Kinase Involved in Pregnancy-Mediated Development of Mammary Secretory Epithelium
2002
Clonal evolution in cancer
2012 StandoutNature
In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells
2003 Standout
The canonical Notch/RBP-J signaling pathway controls the balance of cell lineages in mammary epithelium during pregnancy
2006 StandoutNobel
The Hallmarks of Aging
2013 Standout
Extracellular Matrix-Associated Transforming Growth Factor-β: Role in Cancer Cell Growth and Invasion
1998
Wnt signalling in stem cells and cancer
2005 StandoutNature
Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
2009 StandoutNature
Functional mammary gland development and oncogene-induced tumor formation are not affected by the absence of the retinoblastoma gene
2001
MMTV-induced mutations in mouse mammary tumors: Their potential relevance to human breast cancer
1996
Role of YAP/TAZ in mechanotransduction
2011 StandoutNature
The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
2008 Standout
Functional and molecular characterisation of mammary side population cells
2002
Transgenic and gene knockout mice in cancer research
1995
Stem Cell Characteristics of Transplanted Rat Mammary Clonogens
2000
Tumor suppressor activity of the TGF-β pathway in human cancers
1996
Label-retaining epithelial cells in mouse mammary gland divide asymmetrically and retain their template DNA strands
2005
Tumour stem cells and drug resistance
2005 Standout
Targeted inactivation of the EGF and amphiregulin genes reveals distinct roles for EGF receptor ligands in mouse mammary gland development
1999
Phenotypic consequences of lung-specific inducible expression of FGF-3
2001 StandoutNobel
Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
1997 Standout
Intracisternal Type A Particle-Mediated Activation of the Notch4/int3 Gene in a Mouse Mammary Tumor: Generation of Truncated Notch4/int3 mRNAs by Retroviral Splicing Events
1999 StandoutNobel
STATs and Gene Regulation
1997 StandoutScience
Identification of Notch1 as a Frequent Target for Provirus Insertional Mutagenesis in T-Cell Lymphomas Induced by Leukemogenic Mutants of Mouse Mammary Tumor Virus
2000 StandoutNobel
Programmed assembly of 3-dimensional microtissues with defined cellular connectivity
2009 StandoutNobel
A Perspective on Cancer Cell Metastasis
2011 StandoutScience
The transforming activity of Wnt effectors correlates with their ability to induce the accumulation of mammary progenitor cells
2004
Information networks in the mammary gland
2005
Identification and behavior of epithelial stem cells in the Drosophila ovary
1995
Cancer Immunoediting: Integrating Immunity’s Roles in Cancer Suppression and Promotion
2011 StandoutScience
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
Squamous cell carcinoma and mammary abscess formation through squamous metaplasia inSmad4/Dpc4conditional knockout mice
2003
Dose-dependent induction of distinct phenotypic responses to Notch pathway activation in mammary epithelial cells
2010
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
2018 StandoutNobel
A novel RU486 inducible system for the activation and repression of genes
1998
Notch Signaling: Cell Fate Control and Signal Integration in Development
1999 StandoutScience
MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands
2010 StandoutNobel
Epithelial Plasticity: A Common Theme in Embryonic and Cancer Cells
2013 StandoutScience
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
2015 StandoutNobel
Signal transducer and activator of transcription (Stat) 5 controls the proliferation and differentiation of mammary alveolar epithelium
2001
Stem cells in normal breast development and breast cancer
2003
Functional reconstitution of human eukaryotic translation initiation factor 3 (eIF3)
2011 StandoutNobel
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
Dual Role of Transforming Growth Factor β in Mammary Tumorigenesis and Metastatic Progression
2005
Of Extracellular Matrix, Scaffolds, and Signaling: Tissue Architecture Regulates Development, Homeostasis, and Cancer
2006
Identification of Stem Cell Units in the Terminal End Bud and Duct of the Mouse Mammary Gland
2001
A type 1 serine/threonine kinase receptor that can dorsalize mesoderm in Xenopus.
1995 StandoutNobel
Works of Edith C. Kordon being referenced
Ectopic TGFβ1 Expression in the Secretory Mammary Epithelium Induces Early Senescence of the Epithelial Stem Cell Population
1995
Impairment of mammary lobular development induced by expression of TGF?1 under the control of WAP promoter does not suppress tumorigenesis in MMTV-infected transgenic mice
2001
Detection and location of amphiregulin and Cripto‐1 expression in the developing postnatal mouse mammary gland
1995
Evidence for the transforming activity of a truncated Int6 gene, in vitro
2001
A novel non-mouse mammary tumor virus activation of the Int-3 gene in a spontaneous mouse mammary tumor
1995
Transforming growth factor-alpha promotes mammary tumorigenesis through selective survival and growth of secretory epithelial cells.
1995
Selection of Early-Occurring Mutations Dictates Hormone-Independent Progressionin Mouse Mammary TumorLines
2006
Progression of Pregnancy-Dependent Mouse Mammary Tumors after Long Dormancy Periods. Involvement of Wnt Pathway Activation
2004
Expression of a truncated Int3 gene in developing secretory mammary epithelium specifically retards lobular differentiation resulting in tumorigenesis.
1996
Targeting expression of a transforming growth factor beta 1 transgene to the pregnant mammary gland inhibits alveolar development and lactation.
1993
An entire functional mammary gland may comprise the progeny from a single cell
1998