Citation Impact
Citing Papers
Complement and microglia mediate early synapse loss in Alzheimer mouse models
2016 StandoutScience
A Gene Network Regulating Lysosomal Biogenesis and Function
2009 StandoutScience
Reversal of Neurological Defects in a Mouse Model of Rett Syndrome
2007 StandoutScience
Decreased Clearance of CNS β-Amyloid in Alzheimer’s Disease
2010 StandoutScience
Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis
2006 StandoutScience
Structure of the human TRPM4 ion channel in a lipid nanodisc
2017 StandoutScienceNobel
Sleep Drives Metabolite Clearance from the Adult Brain
2013 StandoutScience
Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses
2003
Preventive methylene blue treatment preserves cognition in mice expressing full-length pro-aggregant human Tau
2015
Genetic Dissection of the Amyloid Precursor Protein in Developmental Function and Amyloid Pathogenesis
2010 StandoutNobel
Roles of tau protein in health and disease
2017
Negatively Charged Amino Acids Near and in Transient Receptor Potential (TRP) Domain of TRPM4 Channel Are One Determinant of Its Ca2+ Sensitivity
2014
Acetylated tau destabilizes the cytoskeleton in the axon initial segment and is mislocalized to the somatodendritic compartment
2016
Oligomer Formation of Tau Protein Hyperphosphorylated in Cells
2014
Cleavage of Tau by calpain in Alzheimer's disease: the quest for the toxic 17 kD fragment
2010
Role of the Tau N-terminal region in microtubule stabilization revealed by newendogenous truncated forms
2015
Pro-aggregant Tau impairs mossy fiber plasticity due to structural changes and Ca++ dysregulation
2015
Tau phosphorylation: the therapeutic challenge for neurodegenerative disease
2009
Axonal Transport RatesIn VivoAre Unaffected by Tau Deletion or Overexpression in Mice
2008
Inducible Expression of Tau Repeat Domain in Cell Models of Tauopathy
2005
Understanding Synapses: Past, Present, and Future
2008 StandoutNobel
A yeast artificial chromosome covering the tyrosinase gene confers copy number-dependent expression in transgenic mice
1993 Nature
Phosphorylated Tau Interacts with c-Jun N-terminal Kinase-interacting Protein 1 (JIP1) in Alzheimer Disease
2009
Mechanisms of neurodegeneration and axonal dysfunction in multiple sclerosis
2014
Requirement of Adenylate Cyclase 1 for the Ephrin-A5-Dependent Retraction of Exuberant Retinal Axons
2006
Selective Capability of SynCAM and Neuroligin for Functional Synapse Assembly
2005 StandoutNobel
Alzheimer Mechanisms and Therapeutic Strategies
2012
Mild overexpression of MeCP2 causes a progressive neurological disorder in mice
2004
Inhibition of tau aggregation in a novel Caenorhabditis elegans model of tauopathy mitigates proteotoxicity
2012
Conservation and divergence of axon guidance mechanisms
1999
Structural Polymorphism of 441-Residue Tau at Single Residue Resolution
2009
Strategies for expressing human antibody repertoires in transgenic mice
1996
Amyloid Oligomers Exacerbate Tau Pathology in a Mouse Model of Tauopathy
2012 Standout
Novel diffusion barrier for axonal retention of Tau in neurons and its failure in neurodegeneration
2011
The Molecular Motor Toolbox for Intracellular Transport
2003
Imaging of cAMP Levels and Protein Kinase A Activity Reveals That Retinal Waves Drive Oscillations in Second-Messenger Cascades
2006 StandoutNobel
Axon pathology in neurological disease: a neglected therapeutic target
2002
Tau phosphorylation and aggregation in Alzheimer's disease pathology
2006
Interaction of Endogenous Tau Protein with Synaptic Proteins Is Regulated by N-Methyl-d-aspartate Receptor-dependent Tau Phosphorylation
2012
The Potential for β-Structure in the Repeat Domain of Tau Protein Determines Aggregation, Synaptic Decay, Neuronal Loss, and Coassembly with Endogenous Tau in Inducible Mouse Models of Tauopathy
2008
Eph receptor signalling casts a wide net on cell behaviour
2005
Electrical signals control wound healing through phosphatidylinositol-3-OH kinase-γ and PTEN
2006 StandoutNatureNobel
Amyloid‐β‐induced toxicity of primary neurons is dependent upon differentiation‐associated increases in tau and cyclin‐dependent kinase 5 expression
2003
Are Tangles as Toxic as They Look?
2011
Trafficking and Proteolytic Processing of APP
2012
β‐amyloid precursor protein can be transported independent of any sorting signal to the axonal and dendritic compartment
2007
Structural Principles of Tau and the Paired Helical Filaments of Alzheimer’s Disease
2007
SUT-1 enables tau-induced neurotoxicity in C . elegans
2007
Stages of the Pathologic Process in Alzheimer Disease: Age Categories From 1 to 100 Years
2011
Tau Mislocalization to Dendritic Spines Mediates Synaptic Dysfunction Independently of Neurodegeneration
2010
cAMP oscillations and retinal activity are permissive for ephrin signaling during the establishment of the retinotopic map
2007 StandoutNobel
Neurotransmitter Release at the Thalamocortical Synapse Instructs Barrel Formation But Not Axon Patterning in the Somatosensory Cortex
2012 StandoutNobel
Tau in physiology and pathology
2015 Standout
Tau post-translational modifications in wild-type and human amyloid precursor protein transgenic mice
2015
Immunogenicity of induced pluripotent stem cells
2011 StandoutNature
PIP2 and PIP3 interact with N-terminus region of TRPM4 channel
2015
Mitochondria: In Sickness and in Health
2012 Standout
TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model
2015 Standout
Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector
2018
EphA receptors and ephrin-A ligands exhibit highly regulated spatial and temporal expression patterns in the developing olfactory system
2002
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
A myocardial lineage derives from Tbx18 epicardial cells
2008 StandoutNature
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
2012 Standout
Parkinson's disease
2015 Standout
Immunopathology of multiple sclerosis
2015 Standout
The axonal transport of mitochondria
2012
Tau-Induced Defects in Synaptic Plasticity, Learning, and Memory Are Reversible in Transgenic Mice after Switching Off the Toxic Tau Mutant
2011
Generation of germline-competent induced pluripotent stem cells
2007 StandoutNatureNobel
A gene expression atlas of the central nervous system based on bacterial artificial chromosomes
2003 StandoutNature
Non-canonical inflammasome activation targets caspase-11
2011 StandoutNature
Alzheimer's Disease
2010 Standout
Neurotoxicity of Amyloid -Protein: Synaptic and Network Dysfunction
2012
Loss of autophagy in the central nervous system causes neurodegeneration in mice
2006 StandoutNature
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
2006 StandoutNature
Overview and recent advances in neuropathology. Part 2: Neurodegeneration
2011
Amyloid‐β oligomers induce synaptic damage via Tau‐dependent microtubule severing by TTLL6 and spastin
2013
Lysosomal Activation Is a Compensatory Response Against Protein Accumulation and Associated Synaptopathogenesis—An Approach for Slowing Alzheimer Disease?
2003
Modulation of EphA Receptor Function by Coexpressed EphrinA Ligands on Retinal Ganglion Cell Axons
1999
The Amyloid State of Proteins in Human Diseases
2012 Standout
Three dimensions of the amyloid hypothesis: time, space and 'wingmen'
2015
The Transthyretin Amyloidoses: From Delineating the Molecular Mechanism of Aggregation Linked to Pathology to a Regulatory-Agency-Approved Drug
2012
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Neurodegenerative diseases: a decade of discoveries paves the way for therapeutic breakthroughs
2004
Soluble Aβ Oligomers Are Rapidly Sequestered from Brain ISF In Vivo and Bind GM1 Ganglioside on Cellular Membranes
2014
Controlling Cell Behavior Electrically: Current Views and Future Potential
2005 Standout
Cognitive defects are reversible in inducible mice expressing pro-aggregant full-length human Tau
2012
Biochemistry and Cell Biology of Tau Protein in Neurofibrillary Degeneration
2012
In VivoMicrodialysis Reveals Age-Dependent Decrease of Brain Interstitial Fluid Tau Levels in P301S Human Tau Transgenic Mice
2011
Bac to the future: The use of bac transgenic mice for neuroscience research
2001
Evolution and Functions of Long Noncoding RNAs
2009 Standout
The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes
2012 Standout
Control of hippocampal dendritic spine morphology through ephrin-A3/EphA4 signaling
2002
Tau phosphorylation in Alzheimer's disease: pathogen or protector?
2005
Oxidative modification and down-regulation of Pin1 in Alzheimer's disease hippocampus: A redox proteomics analysis
2005
The DIAN‐TU Next Generation Alzheimer's prevention trial: Adaptive design and disease progression model
2016
Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export
2012
Single-cell transcriptomic analysis of Alzheimer’s disease
2019 StandoutNature
Angiogenesis as a therapeutic target
2005 StandoutNature
Pathways towards and away from Alzheimer's disease
2004 StandoutNature
Generating transgenic mice from bacterial artificial chromosomes: transgenesis efficiency, integration and expression outcomes
2009
The Cleavage Products of Amyloid-β Precursor Protein Are Sorted to Distinct Carrier Vesicles That Are Independently Transported within Neurites
2009
Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP
2010 StandoutNobel
Molecular motors implicated in the axonal transport of tau and α-synuclein
2005
Axonal Ephrin-As and Odorant Receptors
2003 StandoutNobel
The L1 Cell Adhesion Molecule Is Essential for Topographic Mapping of Retinal Axons
2003
Eph Receptors, Ephrins, and Synaptic Function
2004
Tau interaction with microtubules in vivo
2004
A Century of Alzheimer's Disease
2006 StandoutScience
The serosal mesothelium is a major source of smooth muscle cells of the gut vasculature
2005
Amyloid-β signals through tau to drive ectopic neuronal cell cycle re-entry in Alzheimer's disease
2013
Degradation of tau protein by autophagy and proteasomal pathways
2012
The Slow Axonal Transport of the Microtubule-Associated Protein Tau and the Transport Rates of Different Isoforms and Mutants in Cultured Neurons
2002
Chemically Optimizing Operational Efficiency of Molecular Rotary Motors
2014 StandoutNobel
Microtubule-associated protein tau is essential for long-term depression in the hippocampus
2013
Drug Discovery: A Historical Perspective
2000 StandoutScience
Tau Suppression in a Neurodegenerative Mouse Model Improves Memory Function
2005 StandoutScience
The β-Propensity of Tau Determines Aggregation and Synaptic Loss in Inducible Mouse Models of Tauopathy
2007
Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate
2013 StandoutNobel
Recombineering: a powerful new tool for mouse functional genomics
2001
Netrin-G1: a Novel Glycosyl Phosphatidylinositol-Linked Mammalian Netrin That Is Functionally Divergent from Classical Netrins
2000 StandoutNobel
Protein Kinase MARK/PAR-1 Is Required for Neurite Outgrowth and Establishment of Neuronal Polarity
2002
Dendritic BC200 RNA in aging and in Alzheimer's disease
2007
The Caenorhabditis elegans IMPAS gene, imp-2, is essential for development and is functionally distinct from related presenilins
2004 StandoutNobel
Reducing Endogenous Tau Ameliorates Amyloid ß-Induced Deficits in an Alzheimer's Disease Mouse Model
2007 StandoutScience
Temporally and spatially coordinated roles for Rho, Rac, Cdc42 and their effectors in growth cone guidance by a physiological electric field
2006
Differential Regulation of Dynein and Kinesin Motor Proteins by Tau
2008 Science
YACs to the rescue
1993 StandoutNatureNobel
Finite Scale of Spatial Representation in the Hippocampus
2008 StandoutScienceNobel
Trimeric Tau Is Toxic to Human Neuronal Cells at Low Nanomolar Concentrations
2013
MOLECULAR GRADIENTS AND DEVELOPMENT OF RETINOTOPIC MAPS
2005
Works of Edda Thies being referenced
MARK/PAR1 kinase is a regulator of microtubule-dependent transport in axons
2004
Inhibition of APP Trafficking by Tau Protein Does Not Increase the Generation of Amyloid‐β Peptides
2006
Missorting of Tau in Neurons Causes Degeneration of Synapses That Can Be Rescued by the Kinase MARK2/Par-1
2007
TRPM4 cation channel mediates axonal and neuronal degeneration in experimental autoimmune encephalomyelitis and multiple sclerosis
2012
Neuronal growth cone collapse triggers lateral extensions along trailing axons
1999
Aβ Oligomers Cause Localized Ca 2+ Elevation, Missorting of Endogenous Tau into Dendrites, Tau Phosphorylation, and Destruction of Microtubules and Spines
2010
Transgenic mice generated by pronuclear injection of a yeast artificial chromosome
1992
Independent roles of Rho‐GTPases in growth cone and axonal behavior
2002
Swimming against the Tide: Mobility of the Microtubule-Associated Protein Tau in Neurons
2007
A method for the generation of YAC transgenic mice by pronuclear microinjection
1993
Cellular Localization of Ephrin-A2, Ephrin-A5, and Other Functional Guidance Cues Underlies Retinotopic Development across Species
1998
Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress
2002