Citation Impact
Citing Papers
A Decade of Molecular Studies of Fragile X Syndrome
2002
Promoter-Bound Trinucleotide Repeat mRNA Drives Epigenetic Silencing in Fragile X Syndrome
2014 Science
RIM1α and Interacting Proteins Involved in Presynaptic Plasticity Mediate Prepulse Inhibition and Additional Behaviors Linked to Schizophrenia
2010 StandoutNobel
Linking class-switch recombination with somatic hypermutation
2001 StandoutNobel
Distribution of growth‐associated class I α‐tubulin and class II β‐tubulin mrnas in adult rat brain
1995
Estrogen Receptors: How Do They Signal and What Are Their Targets
2007 Standout
Length-dependent structure formation in Friedreich ataxia (GAA)n{middle dot}(TTC)n repeats at neutral pH
2004
Molecular imaging in living subjects: seeing fundamental biological processes in a new light
2003 Standout
Silencing is golden: negative regulation in the control of neuronal gene transcription
1995
R loops: new modulators of genome dynamics and function
2015
Chromosome fragility at GAA tracts in yeast depends on repeat orientation and requires mismatch repair
2008
Deletion of α‐neurexins does not cause a major impairment of axonal pathfinding or synapse formation
2007 StandoutNobel
Chromatin Remodeling in the Noncoding Repeat Expansion Diseases
2008
Genome-wide demethylation destabilizes CTG·CAG trinucleotide repeats in mammalian cells
2004
The fragile X syndrome repeats form RNA hairpins that do not activate the interferon-inducible protein kinase, PKR, but are cut by Dicer
2003
Glutamate uptake
2001 Standout
Expression of the Smooth Muscle Cell Calponin Gene Marks the Early Cardiac and Smooth Muscle Cell Lineages during Mouse Embryogenesis
1996
Hydrogen peroxide mediates amyloid β protein toxicity
1994 Standout
Modeling familial Alzheimer's disease with induced pluripotent stem cells
2011 StandoutNobel
Role of Replication and CpG Methylation in Fragile X Syndrome CGG Deletions in Primate Cells
2005
The regulation and function of c-fos and other immediate early genes in the nervous system
1990 Standout
Target preference of Type III-A CRISPR-Cas complexes at the transcription bubble
2019 StandoutNobel
Implications of the Human Genome for Understanding Human Biology and Medicine
2001
Mismatch repair and nucleotide excision repair proteins cooperate in the recognition of DNA interstrand crosslinks
2009 StandoutNobel
Characterization of structural features important for T7 RNAP elongation complex stability reveals competing complex conformations and a role for the non-template strand in RNA displacement
1999
Novel Mechanisms of Estrogen Action in the Brain: New Players in an Old Story
1999
Cytosolic and mitochondrial ferritins in the regulation of cellular iron homeostasis and oxidative damage
2010
Transcription as a source of genome instability
2012
Molecular Analysis of Microtubule-Associated Protein-2 Kinase cDNA from Mouse and Rat Brain
1991
Two to Tango: Regulation of Mammalian Iron Metabolism
2010 Standout
Genome Instability and Transcription Elongation Impairment in Human Cells Depleted of THO/TREX
2011
DNA Ligase I Competes with FEN1 to Expand Repetitive DNA Sequences in Vitro
2002
The Growth-Associated Protein GAP-43 Is Increased in the Hippocampus and in the Gyrus Cinguli in Schizophrenia
1999
Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord
2009 Standout
Nerve growth factor and neurotrophin-3 enhance neurite outgrowth and up-regulate the levels of messenger RNA for growth-associated protein GAP-43 and Tα1 α-tubulin in cultured adult rat sensory neurones
1995
Microsatellite repeat instability and neurological disease
2009
Genome-wide Methylation Profiles Reveal Quantitative Views of Human Aging Rates
2012 Standout
Trinucleotide repeats and neurodegenerative disease
2004
DNA triple helices: Biological consequences and therapeutic potential
2008
Search-and-replace genome editing without double-strand breaks or donor DNA
2019 StandoutNature
Understanding the molecular basis of fragile X syndrome
2000
Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis
2019 StandoutNobel
Repeat instability as the basis for human diseases and as a potential target for therapy
2010
Neuronal pathfinding is abnormal in mice lacking the neuronal growth cone protein GAP-43
1995
The Friedreich ataxia GAA repeat expansion mutation induces comparable epigenetic changes in human and transgenic mouse brain and heart tissues
2007
Ectopic hypermethylation of flower-specific genes in Arabidopsis
2000
MutLα and Proliferating Cell Nuclear Antigen Share Binding Sites on MutSβ
2010 StandoutNobel
Unique features of long non-coding RNA biogenesis and function
2015 Standout
Purkinje cell injury, structural plasticity and fusion in patients with Friedreich’s ataxia
2016
Mechanism of Stimulation of Human DNA Ligase I by the Rad9-Rad1-Hus1 Checkpoint Complex
2006 StandoutNobel
Frequent but biased class switch recombination in the Sμ flanking regions
1998 StandoutNobel
Local protein synthesis and its role in synapse-specific plasticity
2000 StandoutNobel
Immunolocalization of B-50 (GAP-43) in the mouse olfactory bulb: Predominant presence in preterminal axons
1992
Genome instability: a mechanistic view of its causes and consequences
2008
Histone deacetylase inhibitors reverse gene silencing in Friedreich's ataxia
2006
Estrogenic regulation and sex dimorphism of growth-associated protein 43 kDa (GAP-43) messenger RNA in the rat
1991
Cell cycle, CDKs and cancer: a changing paradigm
2009 Standout
Chemistry of Class 1 CRISPR-Cas effectors: Binding, editing, and regulation
2020 StandoutNobel
Production and Actions of Estrogens
2002 Standout
Epigenetic modifications and human disease
2010 Standout
Chromatin remodeller SMARCA4 recruits topoisomerase 1 and suppresses transcription-associated genomic instability
2016 StandoutNobel
Mechanisms of trinucleotide repeat instability during human development
2010
Friedreich's ataxia: Pathology, pathogenesis, and molecular genetics
2011
RNA: DNA complex formation upon transcription of immunoglobulin switch regions: implications for the mechanism and regualtion of class switch recombination
1995
Trk receptors: mediators of neurotrophin action
2001 StandoutNobel
NGF induction of the gene encoding the protease transin accompanies neuronal differentiation in PC12 cells
1989
Analysis of DNA Replication Intermediates Suggests Mechanisms of Repeat Sequence Expansion
2003
Friedreich's Ataxia Induced Pluripotent Stem Cells Model Intergenerational GAA⋅TTC Triplet Repeat Instability
2010
Genetic Demonstration of a Role for PKA in the Late Phase of LTP and in Hippocampus-Based Long-Term Memory
1997 StandoutNobel
The glutamatergic nerve terminal
1993
Molecular Regulation of Vascular Smooth Muscle Cell Differentiation in Development and Disease
2004 Standout
DNA methylation and human disease
2005 Standout
The mitochondrial protein frataxin prevents nuclear damage
2002
Cell fate determination in the peripheral nervous system: The sympathoadrenal progenitor
1993
R Loops: From Transcription Byproducts to Threats to Genome Stability
2012
Regional differences in endothelin converting enzyme activity in rat brain: inhibition by phosphoramidon and EDTA
1992 StandoutNobel
Ca2+ Influx Regulates BDNF Transcription by a CREB Family Transcription Factor-Dependent Mechanism
1998 Standout
Iron Regulatory Proteins: From Molecular Mechanisms to Drug Development
2010
PCNA function in the activation and strand direction of MutLα endonuclease in mismatch repair
2010 StandoutNobel
Genome Regulation by Long Noncoding RNAs
2012 Standout
R loops stimulate genetic instability of CTG·CAG repeats
2009
Neurotrophins: Roles in Neuronal Development and Function
2001 Standout
Response to “The Reality of Pervasive Transcription”
2011
Molecular Mechanism of Class Switch Recombination: Linkage with Somatic Hypermutation
2002 StandoutNobel
EUKARYOTIC CYTOSINE METHYLTRANSFERASES
2005 Standout
Modeling hepatitis C virus infection using human induced pluripotent stem cells
2012 StandoutNobel
Neuronal Expression of the 5HT3Serotonin Receptor Gene Requires Nuclear Factor 1 Complexes
1998 StandoutNobel
Nerve growth factor-induced neuronal differentiation after dominant repression of both type I and type II cAMP-dependent protein kinase activities
1991
Early VGLUT1-specific parallel fiber synaptic deficits and dysregulated cerebellar circuit in the KIKO mouse model of Friedreich ataxia
2017
Neurodegeneration in Friedreich’s Ataxia: From Defective Frataxin to Oxidative Stress
2013
Schwannoma-derived growth factor promotes the neuronal differentiation and survival of PC12 cells.
1992
Identification of brain-derived neurotrophic factor promoter regions mediating tissue-specific, axotomy-, and neuronal activity-induced expression in transgenic mice.
1995
An Unbiased cDNA Library Prepared from IsolatedAplysiaSensory Neuron Processes Is Enriched for Cytoskeletal and Translational mRNAs
2003 StandoutNobel
Ischemic Cell Death in Brain Neurons
1999 Standout
Mitogen-Activated Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human
1999 Standout
Expression of the potent vasoconstrictor endothelin in the human central nervous system.
1990
Flap Endonuclease 1: A Central Component of DNA Metabolism
2004
A Transcription-Dependent Switch Controls Competence of Adult Neurons for Distinct Modes of Axon Growth
1997
Structural Basis for the Transition from Initiation to Elongation Transcription in T7 RNA Polymerase
2002 StandoutScienceNobel
Extrahelical (CAG)/(CTG) triplet repeat elements support proliferating cell nuclear antigen loading and MutLα endonuclease activation
2013 StandoutNobel
Quantitative Regulation of Class Switch Recombination by Switch Region Transcription
2001 StandoutNobel
Evolutionary Comparison of the Mechanism of DNA Cleavage with Respect to Immune Diversity and Genomic Instability
2012 StandoutNobel
The Molecular Biology of Axon Guidance
1996 StandoutScience
The human Rad9–Rad1–Hus1 checkpoint complex stimulates flap endonuclease 1
2004 StandoutNobel
Mouse neurexin-1α deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments
2009 StandoutNobel
Long CTG Tracts from the Myotonic Dystrophy Gene Induce Deletions and Rearrangements during Recombination at the APRT Locus in CHO Cells
2003
AID to overcome the limitations of genomic information
2005 StandoutNobel
Works of Ed Grabczyk being referenced
Progressive GAA·TTC Repeat Expansion in Human Cell Lines
2009
A persistent RNA{middle dot}DNA hybrid formed by transcription of the Friedreich ataxia triplet repeat in live bacteria, and by T7 RNAP in vitro
2007
GAP-43 gene expression during development: persistence in a distinctive set of neurons in the mature central nervous system
1989
Alleviating transcript insufficiency caused by Friedreich's ataxia triplet repeats
2000
Long Uninterrupted CGG Repeats within the First Exon of the Human FMR1 Gene Are Not Intrinsically Unstable in Transgenic Mice
1998
Ferritin L and H Subunits Are Differentially Regulated on a Post-transcriptional Level
2007
A Novel Tandem Reporter Quantifies RNA Polymerase II Termination in Mammalian Cells
2009
The GAATTC triplet repeat expanded in Friedreich's ataxia impedes transcription elongation by T7 RNA polymerase in a length and supercoil dependent manner
2000
Cloning and Characterization of the Rat Gene Encoding GAP‐43
1990
A Long Purine-Pyrimidine Homopolymer Acts as a Transcriptional Diode
1995
Regional FMRP deficits and large repeat expansions into the full mutation range in a new Fragile X premutation mouse model
2007
Generation of Microgram Quantities of Trinucleotide Repeat Tracts of Defined Length, Interspersion Pattern, and Orientation
1999
Dual regulation of GAP-43 gene expression by nerve growth factor and glucocorticoids.
1988
DNA repeat expansions and human disease
2000
GAP-43 transgenic mice: dispersed genomic sequences confer a GAP-43- like expression pattern during development and regeneration
1994