Citation Impact
Citing Papers
Sex Differences in the Gut Microbiome Drive Hormone-Dependent Regulation of Autoimmunity
2013 StandoutScience
EglN2 associates with the NRF 1‐ PGC 1α complex and controls mitochondrial function in breast cancer
2015 StandoutNobel
Optical control of insulin release using a photoswitchable sulfonylurea
2014
Crosstalk between the canonical NF-κB and Notch signaling pathways inhibits Pparγ expression and promotes pancreatic cancer progression in mice
2011
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
2009 StandoutNature
Inhibition of Silencing and Accelerated Aging by Nicotinamide, a Putative Negative Regulator of Yeast Sir2 and Human SIRT1
2002
Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health
2004
Nicotinamide inhibits enhanced in vitro production of interleukin-12 and tumour necrosis factor-α in peripheral whole blood of people at high risk of developing Type 1 diabetes and people with newly diagnosed Type 1 diabetes
2000
Type 2 diabetes and cancer: umbrella review of meta-analyses of observational studies
2015
Severe Hypoglycemia and Risks of Vascular Events and Death
2010 Standout
Hepatocellular carcinoma
2018 Standout
Linkage and associated studies of schizophrenia
2000
Pathophysiology of sex hormone binding globulin (SHBG): Relation to insulin
1991
Insulin-IGF2 region on chromosome 11p encodes a gene implicated in HLA-DR4-dependent diabetes susceptibility
1991 Nature
The Effect of Infections on Susceptibility to Autoimmune and Allergic Diseases
2002 Standout
Survival as a function of HbA1c in people with type 2 diabetes: a retrospective cohort study
2010
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
2013 StandoutNature
Hallmarks of aging: An expanding universe
2023 Standout
Molecular cloning and expression of the fas ligand, a novel member of the tumor necrosis factor family
1993 Standout
Epidemiology of childhood IDDM in Northern Ireland 1989?1994: Low incidence in areas with highest population density and most household crowding
1996
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
2001 StandoutNature
Prognostic implications of glucose-lowering treatment in patients with acute myocardial infarction and diabetes: experiences from an extended follow-up of the Diabetes Mellitus Insulin–Glucose Infusion in Acute Myocardial Infarction (DIGAMI) 2 Study
2011
Inhibition of Sex Hormone-Binding Globulin Production in the Human Hepatoma (Hep G2) Cell Line by Insulin and Prolactin*
1988
Interferon alpha—a potential link in the pathogenesis of viral-induced type 1 diabetes and autoimmunity
2004
Insulin analogues and cancer risk: cause for concern orcause célèbre?
2010
The Therapeutic Potential of Poly(ADP-Ribose) Polymerase Inhibitors
2002 Standout
Celiac Disease
2007 Standout
Declining incidence of severe retinopathy and persisting decrease of nephropathy in an unselected population of Type 1 diabetes—the Linköping Diabetes Complications Study
2004
Therapeutic window for nicotinamide following transient focal cerebral ischemia
2002
Two Genetic Loci Regulate T Cell–Dependent Islet Inflammation and Drive Autoimmune Diabetes Pathogenesis
2000
Diabetic Retinopathy
2012 Standout
A Phase 3 Randomized Trial of Nicotinamide for Skin-Cancer Chemoprevention
2015
The Emerging Role of CTLA-4 as an Immune Attenuator
1997 StandoutNobel
The safety profile of exogenous insulin in people with type 2 diabetes: justification for concern
2011
Prediabetes: prediction and prevention trials
2004
Diabetes and cancer
2009
Essential role for interferon-gamma and interleukin-6 in autoimmune insulin-dependent diabetes in NOD/Wehi mice.
1991
Polycystic Ovary Syndrome
1995 Standout
Time-resolved fluorescence imaging in islet cell autoantibody quantitation
1997
The tissue distribution of tumor necrosis factor biosynthesis during endotoxemia.
1992 StandoutNobel
Cytokine gene polymorphism in human disease: on-line databases
1999
Global and societal implications of the diabetes epidemic
2001 StandoutNature
Does Insulin Therapy Promote, Reduce, or Have a Neutral Effect on Cancers?
2010
Gut metagenome in European women with normal, impaired and diabetic glucose control
2013 StandoutNature
CTLA4 Alanine-17 Confers Genetic Susceptibility to Graves’ Disease and to Type 1 Diabetes Mellitus1
1997
Cell-mediated cytotoxicity
1993 StandoutNobel
Evidence for enhanced rates of complement activation in serum from patients with newly diagnosed insulin-dependent diabetes mellitus exposed to rat islet cells and complement-dependent induction of islet cell apoptosis
1999
The TNF receptor superfamily of cellular and viral proteins: Activation, costimulation, and death
1994 Standout
The British Diabetic Association Cohort Study, I: all‐cause mortality in patients with insulin‐treated diabetes mellitus
1999
Analysis of tumor necrosis factor promoter responses to ultraviolet light.
1994 StandoutNobel
Lymphotoxin ?, a novel member of the TNF family that forms a heteromeric complex with lymphotoxin on the cell surface
1993
Nicotinamide decreases MHC class II but not MHC class I expression and increases intercellular adhesion molecule-1 structures in non-obese diabetic mouse pancreas
1999
Molecular mechanisms of cancer development in obesity
2011
The quest to slow ageing through drug discovery
2020
Focal expression of interleukin-2 does not break unresponsiveness to "self" (viral) antigen expressed in beta cells but enhances development of autoimmune disease (diabetes) after initiation of an anti-self immune response.
1995 StandoutNobel
What We Talk About When We Talk About Fat
2014 Standout
Increased incidence of non-insulin-dependent diabetes mellitus among adolescents
1996
A Dominant Complement Fixation Pathway for Pneumococcal Polysaccharides Initiated by SIGN-R1 Interacting with C1q
2006 StandoutNobel
Epidemiological aspects of neoplasms in diabetes
2010
Cancer-related inflammation
2008 StandoutNature
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
2003 StandoutNature
Prediabetes: a high-risk state for diabetes development
2012 Standout
Development of Insulitis and Diabetes in B Cell-Deficient NOD Mice
1997
Epidemiology and Estimated Population Burden of Selected Autoimmune Diseases in the United States
1997 Standout
Innate immunity and intestinal microbiota in the development of Type 1 diabetes
2008 StandoutNature
A review of the recent epidemiological data on the worldwide incidence of Type 1 (insulin-dependent) diabetes mellitus
1993
The Tumor Necrosis Factor Ligand and Receptor Families
1996 StandoutNobel
Interleukin-1 polymorphisms associated with increased risk of gastric cancer
2000 StandoutNature
Pancreatic expression of interleukin-4 abrogates insulitis and autoimmune diabetes in nonobese diabetic (NOD) mice.
1996
Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM).
1993 Standout
Early expression of antiinsulin autoantibodies of humans and the NOD mouse: Evidence for early determination of subsequent diabetes
2000
Investigation of the Role of B-Cells in Type 1 Diabetes in the NOD Mouse
2004
Lanthanide Luminescence for Biomedical Analyses and Imaging
2010 Standout
Metformin Associated With Lower Cancer Mortality in Type 2 Diabetes
2009
Interactions Between the Microbiota and the Immune System
2012 StandoutScience
PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice
2011 StandoutNobel
Gluten, major histocompatibility complex, and the small intestine
1992 Standout
Diabetes and Cancer
2010 Standout
Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man
1985 Standout
TYPE I INTERFERONS (α/β) IN IMMUNITY AND AUTOIMMUNITY
2004 StandoutNobel
Intensive Diabetes Treatment and Cardiovascular Disease in Patients with Type 1 Diabetes
2005 Standout
Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs
2005 Standout
Artificial Molecular Machines
2015 Standout
The Future of Genetic Studies of Complex Human Diseases
1996 StandoutScience
Genetic Dissection of Complex Traits
1994 StandoutScience
THE BASAL PLASMA GLUCOSE: A SIMPLE RELEVANT INDEX OF MATURITY‐ONSET DIABETES
1981
CD25+ CD4+ T Cells, Expanded with Dendritic Cells Presenting a Single Autoantigenic Peptide, Suppress Autoimmune Diabetes
2004 StandoutNobel
Investigating Metformin for Cancer Prevention and Treatment: The End of the Beginning
2012
Effect of COMT Val 108/158 Met genotype on frontal lobe function and risk for schizophrenia
2001 Standout
Emerging Targets in Photopharmacology
2016 StandoutNobel
Pioglitazone and Bladder Cancer
2011
Tissue-specific expression of B7x protects from CD4 T cell–mediated autoimmunity
2011 StandoutNobel
Molecular characterization of murine and human OX40/OX40 ligand systems: identification of a human OX40 ligand as the HTLV-1-regulated protein gp34.
1994 StandoutNobel
Basal Insulin and Cardiovascular and Other Outcomes in Dysglycemia
2012 Standout
Androgen treatment prevents diabetes in nonobese diabetic mice.
1992
Obesity and the Environment: Where Do We Go from Here?
2003 StandoutScience
Spontaneous Autoimmune Diabetes in Monoclonal T Cell Nonobese Diabetic Mice
1997
Unraveling Function in the TNF Ligand and Receptor Families
1994 StandoutScienceNobel
Works of E.A.M. Gale being referenced
Incidence of insulin dependent diabetes in England: a study in the Oxford region, 1985-6.
1989
Restriction fragment length polymorphism analysis of HLA haplotypes in families with Type I diabetes mellitus
1990
Islet autoantibody markers in IDDM: risk assessment strategies yielding high sensitivity
1995
Safety of high-dose nicotinamide: a review
2000
Diabetes and cancer (2): evaluating the impact of diabetes on mortality in patients with cancer
2012
A comparison of the prevalence of islet autoantibodies in children from two countries with differing incidence of diabetes
2001
BASAL AND STIMULATED INSULIN LEVELS RISE WITH ADVANCING PUBERTY
1988
The influence of glucose-lowering therapies on cancer risk in type 2 diabetes
2009
TNF‐alpha GENE POLYMORPHISMS: ASSOCIATION WITH TYPE I (INSULIN‐DEPENDENT) DIABETES MELLITUS
1989
Lessons from the NOD mouse for the pathogenesis and immunotherapy of human Type 1 (insulin-dependent) diabetes mellitus
1989
The natural history of lymphocyte subsets infiltrating the pancreas of NOD mice
1989
Insulin and Growth Factors Adaptation to Normal Puberty
1992
SELF-MONITORING OF BLOOD-GLUCOSE
1978
Progression to diabetes in relatives with islet autoantibodies. Is it inevitable?
1999
DNA polymorphic haplotypes on the short arm of chromosome 11 and the inheritance of type I diabetes mellitus.
1986
Optimized autoantibody-based risk assessment in family members. Implications for future intervention trials.
1999
Nicotinamide: Potential for the Prevention of Type 1 Diabetes?
1996