Citation Impact
Citing Papers
Neuronal apoptosis linked to EglN3 prolyl hydroxylase and familial pheochromocytoma genes: Developmental culling and cancer
2005 StandoutNobel
Involvement of the Acid Sphingomyelinase Pathway in UVA-induced Apoptosis
2001
Signal transduction through the sphingomyelin pathway
1994
Long Chain Ceramides Activate Protein Phosphatase-1 and Protein Phosphatase-2A
1999
Imaging beyond the proteome
2012 StandoutNobel
Structure and function of the spleen
2005 Standout
Models to Study Gravitational Biology of Mammalian Reproduction1
2002
Inflammatory links between obesity and metabolic disease
2011 Standout
The Hindlimb Unloading Rat Model: Literature Overview, Technique Update and Comparison with Space Flight Data
2005
De Novo Sphingolipid Biosynthesis: A Necessary, but Dangerous, Pathway
2002
Calcium's Role in Mechanotransduction during Muscle Development
2014 Standout
Insulin treatment increases myocardial ceramide accumulation and disrupts cardiometabolic function
2015
Ceramides and other bioactive sphingolipid backbones in health and disease: Lipidomic analysis, metabolism and roles in membrane structure, dynamics, signaling and autophagy
2006
Changes in Lipidome Composition during Brain Development in Humans, Chimpanzees, and Macaque Monkeys
2017 StandoutNobel
Sphingolipids and their metabolism in physiology and disease
2017 Standout
Ceramide: a novel second messenger
1992
Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes
2008 Standout
Biochemical Characterization of the Reverse Activity of Rat Brain Ceramidase
2001
The von Hippel‐Lindau Tumor Suppressor Protein: An Update
2007 StandoutNobel
Effect of Solar Particle Event Radiation and Hindlimb Suspension on Gastrointestinal Tract Bacterial Translocation and Immune Activation
2012 StandoutNobel
Fumonisins, mycotoxins of increasing importance: Their nature and their effects
1996
Principles of bioactive lipid signalling: lessons from sphingolipids
2008 Standout
De Novo Ceramide Regulates the Alternative Splicing of Caspase 9 and Bcl-x in A549 Lung Adenocarcinoma Cells
2002
Differential Roles of de Novo Sphingolipid Biosynthesis and Turnover in the “Burst” of Free Sphingosine and Sphinganine, and Their 1-Phosphates and N-Acyl-Derivatives, That Occurs upon Changing the Medium of Cells in Culture
1995
An update of the enzymology and regulation of sphingomyelin metabolism
1990
The Formation of Ceramide-1-phosphate during Neutrophil Phagocytosis and Its Role in Liposome Fusion
1998 StandoutNobel
Sphingosine 1-phosphate signaling pathway in inner ear biology. New therapeutic strategies for hearing loss?
2015
Cell regulation by sphingosine and more complex sphingolipids
1991
Broad-Spectrum Antibiotic or G-CSF as Potential Countermeasures for Impaired Control of Bacterial Infection Associated with an SPE Exposure during Spaceflight
2015 StandoutNobel
Cloning and Characterization of a Protein Kinase A Anchoring Protein (AKAP)-related Protein That Interacts with and Regulates Sphingosine Kinase 1 Activity
2002
Sphingosine-induced apoptosis is dependent on lysosomal proteases
2001
Designing anticancer drugs via the achilles heel: ceramide, allylic ketones, and mitochondria
2003
Simulated weightlessness-induced attenuation of testosterone production may be responsible for bone loss
1999
Hindlimb Suspension and SPE-Like Radiation Impairs Clearance of Bacterial Infections
2014 StandoutNobel
Formation of endogenous free sphingoid bases in cells induced by changing medium conditions
1994
Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance
2008 Standout
Ceramide 1-phosphate/ceramide, a switch between life and death
2006
Enhanced Phagocytosis through Inhibition of de Novo Ceramide Synthesis
2003 StandoutNobel
Ceramide in the eukaryotic stress response
2000
Mutations in SPTLC1, encoding serine palmitoyltransferase, long chain base subunit-1, cause hereditary sensory neuropathy type I
2001
The SPTLC3 Subunit of Serine Palmitoyltransferase Generates Short Chain Sphingoid Bases
2009
The mystery of membrane organization: composition, regulation and roles of lipid rafts
2017 Standout
Identification and Characterization of Saccharomyces cerevisiae Dihydrosphingosine-1-phosphate Phosphatase
1997
Reactive oxygen species have a causal role in multiple forms of insulin resistance
2006 StandoutNature
Neuroblastoma
2007 Standout
Endotoxemia and hepatic injury in a rodent model of hindlimb unloading
2003
Molecular mechanisms of necroptosis: an ordered cellular explosion
2010 Standout
Inhibition of Carnitine Palmitoyltransferase I Augments Sphingolipid Synthesis and Palmitate-induced Apoptosis
1997 StandoutNobel
New cancer targets emerging from studies of the Von Hippel‐Lindau tumor suppressor protein
2010 StandoutNobel
The von Hippel–Lindau protein, HIF hydroxylation, and oxygen sensing
2005 StandoutNobel
Sphingosine Kinase Type 1 Promotes Estrogen-Dependent Tumorigenesis of Breast Cancer MCF-7 Cells
2002
Increase of Ceramide and Induction of Mixed Apoptosis/Necrosis by N-(4-Hydroxyphenyl)- retinamide in Neuroblastoma Cell Lines
1999
Revisiting STAT3 signalling in cancer: new and unexpected biological functions
2014 Standout
Emptying of intracellular Ca2+ stores releases a novel small messenger that stimulates Ca2+ influx
1993 StandoutNatureNobel
Sphingosine-1-phosphate: an enigmatic signalling lipid
2003 Standout
Synergistic Cytotoxicity in Solid Tumor Cell Lines Between N-(4-Hydroxyphenyl)retinamide and Modulators of Ceramide Metabolism
2000
Ceramide synthases in biomedical research
2015
The Role of Sphingosine Kinase in the Signaling Initiated at the High-Affinity Receptor for IgE (FcεRI) in Mast Cells
2000
Integrated signalling pathways for mast-cell activation
2006 Standout
Expression of the Sphingosine 1-Phosphate Receptor, S1P1, on T-cells Controls Thymic Emigration
2004
Activation of a Plasma Membrane–Associated Neutral Sphingomyelinase and Concomitant Ceramide Accumulation During IgG-Dependent Phagocytosis in Human Polymorphonuclear Leukocytes
1998 StandoutNobel
Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis.
1994 Standout
Sphingosine inhibits phosphatidate phosphohydrolase in human neutrophils by a protein kinase C-independent mechanism
1991
Gravity Force Transduced by the MEC-4/MEC-10 DEG/ENaC Channel Modulates DAF-16/FoxO Activity in Caenorhabditis elegans
2007 StandoutNobel
The sphingosine kinase 1/sphingosine‐1‐phosphate pathway mediates COX‐2 induction and PGE 2 production in response to TNF‐α
2003
Use of d -erythro-sphingosine as a pharmacological inhibitor of protein kinase C in human platelets
1991
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet–Induced Obesity and Diabetes in Mice
2008 Standout
A Role for Sphingolipids in Producing the Common Features of Type 2 Diabetes, Metabolic Syndrome X, and Cushing’s Syndrome
2005
Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis
2016 Standout
Characterization of a ceramide kinase activity from human leukemia (HL-60) cells. Separation from diacylglycerol kinase activity.
1990
Intracellular Calcium Release Mediated by Sphingosine Derivatives Generated in Cells
1990 Science
MALDI Imaging of Lipid Biochemistry in Tissues by Mass Spectrometry
2011
Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor
2002 StandoutNobel
Ceramide 1-phosphate, a novel phospholipid in human leukemia (HL-60) cells. Synthesis via ceramide from sphingomyelin.
1990
Signal transduction of stress via ceramide
1998
Ceramide stimulates epidermal growth factor receptor phosphorylation in A431 human epidermoid carcinoma cells. Evidence that ceramide may mediate sphingosine action
1991
Sphingoid base 1-phosphate phosphatase: A key regulator of sphingolipid metabolism and stress response
1998
Programmed Cell Death Induced by Ceramide
1993 StandoutScience
Mycotoxins
2003 Standout
Fumonisin B1 inhibits sphingosine (sphinganine) N-acyltransferase and de novo sphingolipid biosynthesis in cultured neurons in situ.
1993
Activation of a Plasma Membrane–Associated Neutral Sphingomyelinase and Concomitant Ceramide Accumulation During IgG-Dependent Phagocytosis in Human Polymorphonuclear Leukocytes
1998 StandoutNobel
Sphingosine Blocks Human Polymorphonuclear Leukocyte Phagocytosis Through Inhibition of Mitogen-Activated Protein Kinase Activation
1999 StandoutNobel
Inhibition of sphingolipid biosynthesis by fumonisins. Implications for diseases associated with Fusarium moniliforme
1991 Standout
Oxidative Stress and Stress-Activated Signaling Pathways: A Unifying Hypothesis of Type 2 Diabetes
2002 Standout
Functions of Ceramide in Coordinating Cellular Responses to Stress
1996 StandoutScience
CD1d-Restricted and TCR-Mediated Activation of V α 14 NKT Cells by Glycosylceramides
1997 StandoutScience
Spaceflight induces changes in splenocyte subpopulations: effectiveness of ground-based models
2000
Obesity-Related Derangements in Metabolic Regulation
2006
Role of ceramide as a lipid mediator of 1 alpha,25-dihydroxyvitamin D3-induced HL-60 cell differentiation.
1990
Sphingolipid metabolism: roles in signal transduction and disruption by fumonisins.
2001
Ceramide inhibition of phospholipase D and its relationship to RhoA and ARF1 translocation in GTPγS-stimulated polymorphonuclear leukocytes
2003 StandoutNobel
Sphingolipids, Insulin Resistance, and Metabolic Disease: New Insights from in Vivo Manipulation of Sphingolipid Metabolism
2008
Ceramide Inhibits IgG-Dependent Phagocytosis in Human Polymorphonuclear Leukocytes
1997 StandoutNobel
Expression of neutral sphingomyelinase‐2 (NSMase‐2) in primary rat hepatocytes modulates IL‐β‐induced JNK activation
2004
Cellular and Molecular Dissection of Reperfusion Injury
2000 StandoutNobel
Sphingosine-dependent apoptosis: A unified concept based on multiple mechanisms operating in concert
2004
Satellite Cells and the Muscle Stem Cell Niche
2013 Standout
The dihydrosphingosine-1-phosphate phosphatases of Saccharomyces cerevisiae are important regulators of cell proliferation and heat stress responses
1999
Regulation of Mammalian Autophagy in Physiology and Pathophysiology
2010 Standout
Genetics of Sensory Mechanotransduction
2002 StandoutNobel
Works of E. Wang being referenced
Chronic toxicity of fumonisins from Fusarium moniliforme culture material (M-1325) to mink
1995
Fumonisin B1 Alters Sphingolipid Metabolism and Disrupts the Barrier Function of Endothelial Cells in Culture
1995
[3] Ceramide synthase
2000
Alteration in sphingolipid metabolism: bioassays for fumonisin- and ISP-I-like activity in tissues, cells and other matrices
1999
Fumonisin Toxicity and Sphingolipid Biosynthesis
1996
Effects of Feeding Fusarium moniliforme Culture Material, Containing Known Levels of Fumonisin B1, on the Young Broiler Chick
1993
Sphingolipids—The Enigmatic Lipid Class: Biochemistry, Physiology, and Pathophysiology
1997
Characterization of Cell-cycle Arrest by Fumonisin B1 in CV-1 Cells
1998
Regulation of de novo sphingolipid biosynthesis and the toxic consequences of its disruption
2001
Analyses of plasma for metabolic and hormonal changes in rats flown aboard COSMOS 2044
1992
Free Sphingosine Formation from Endogenous Substrates by a Liver Plasma Membrane System with a Divalent Cation Dependence and a Neutral pH Optimum
1989
Differences in glycogen, lipids, and enzymes in livers from rats flown on COSMOS 2044
1992