Citation Impact
Citing Papers
Serotonin Transporter Genetic Variation and the Response of the Human Amygdala
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Thyroid and adrenal axis in major depression: a controlled study in outpatients
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The origins of sex differences in depressive disorder: bridging the gap
1996
A Meta-Analysis of Cytokines in Major Depression
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Cytokines and Glucocorticoid Receptor Signaling
2009
Major Depressive Disorder and Inflammatory Markers in Elderly Patients With Heart Failure
2007
Altered expression of CD4+CD25+ regulatory T cells and its 5-HT1a receptor in patients with major depression disorder
2009
Th2 cytokine response in Major Depressive Disorder patients before treatment
2006
Hypothalamo-pituitary-adrenal function in patients with depressive disorders is correlated with baseline cytokine levels, but not with cytokine responses to hydrocortisone
2003
The relationship between subtypes of depression and cardiovascular disease: a systematic review of biological models
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Dexamethasone-induced effects on lymphocyte distribution and expression of adhesion molecules in treatment-resistant depression
2002
Association Study of the Interleukin-1beta (C-511T) Genetic Polymorphism with Major Depressive Disorder, Associated Symptomatology, and Antidepressant Response
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Increased plasma peroxides and serum oxidized low density lipoprotein antibodies in major depression: Markers that further explain the higher incidence of neurodegeneration and coronary artery disease
2010
Immune–endocrine host response to endotoxin in major depression
2006
Gender differences in depression in representative national samples: Meta-analyses of diagnoses and symptoms.
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The gut-brain barrier in major depression: intestinal mucosal dysfunction with an increased translocation of LPS from gram negative enterobacteria (leaky gut) plays a role in the inflammatory pathophysiology of depression.
2008
Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways
2012
Increased serum tumor necrosis factor alpha concentrations in major depression and multiple sclerosis
2001
Interleukin-6 levels and HPA axis activation in breast cancer patients with major depressive disorder
2007
Association of depression with medical illness: does cortisol play a role?
2003
A detailed examination of cytokine abnormalities in Major Depressive Disorder
2007
Pro- and Anti-Inflammatory Cytokine Balance in Major Depression: Effect of Sertraline Therapy
2007
Increased IgA and IgM responses against gut commensals in chronic depression: Further evidence for increased bacterial translocation or leaky gut
2012
From stress to inflammation and major depressive disorder: A social signal transduction theory of depression.
2014 Standout
Assessment of the immune system activity in Iranian patients with Major Depression Disorder (MDD).
2007
Interleukin (IL)-6, tumour necrosis factor alpha (TNF-α) and soluble interleukin-2 receptors (sIL-2R) are elevated in patients with major depressive disorder: A meta-analysis and meta-regression
2011
Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: Evidence for an immune-modulated glutamatergic neurotransmission?
2011
Beyond the serotonin hypothesis: Mitochondria, inflammation and neurodegeneration in major depression and affective spectrum disorders
2010
NLRP3 inflammasome is activated in mononuclear blood cells from patients with major depressive disorder
2013
Pathways Linking Major Depression and Immunity in Ambulatory Female Patients
1999
Psychological Stress and Disease
2007 Standout
Increase in Interleukin-1β in Late-Life Depression
2004
Inflammation and Its Discontents: The Role of Cytokines in the Pathophysiology of Major Depression
2009 Standout
Cytokine profiles in women with different subtypes of major depressive disorder
2005
Blood levels of cytokines in elderly patients with major depressive disorder
1998
Changes in the immune system in depression and dementia: causal or co‐incidental effects?
2001
Long-term Cognitive Impairment and Functional Disability Among Survivors of Severe Sepsis
2010 Standout
No health without mental health
2007 Standout
Increased 8-hydroxy-deoxyguanosine, a marker of oxidative damage to DNA, in major depression and myalgic encephalomyelitis / chronic fatigue syndrome.
2009
Neutral amino acid availability in two major psychiatric disorders
1995
Primary dysthymia: A study of several psychosocial, endocrine and immune correlates
1996
Child abuse: Adolescent records vs. adult recall
1990 Standout
Beta adrenergic blockade decreases the immunomodulatory effects of social disruption stress
2012
Cytokines, “Depression Due to A General Medical Condition,” and Antidepressant Drugs
1999
Increased plasma levels of 8-iso-PGF2α and IL-6 in an elderly population with depression
2008
The inflammasome: Pathways linking psychological stress, depression, and systemic illnesses
2012
Evidence for an immune response in major depression: A review and hypothesis
1995
Influence of psychological stress on immune-inflammatory variables in normal humans. Part II. Altered serum concentrations of natural anti-inflammatory agents and soluble membrane antigens of monocytes and T lymphocytes
1999
T‐helper 1/T‐helper 2 cytokine imbalance and clinical phenotypes of acute‐phase major depression
2007
Plasma Concentrations of Interleukin-1β, Interleukin-6, Soluble Interleukin-2 Receptor and Tumor Necrosis Factor α of Depressed Patients in Japan
2001
Elevated levels of serum interleukin-1β in combat-related posttraumatic stress disorder
1997
The relationship between social support and physiological processes: A review with emphasis on underlying mechanisms and implications for health.
1996 Standout
Association of Interleukin‐6 and Other Biologic Variables with Depression in Older People Living in the Community
1999
Is Caregiving Hazardous to One's Physical Health? A Meta-Analysis.
2003 Standout
Multiple aberrations in shared inflammatory and oxidative & nitrosative stress (IO&NS) pathways explain the co-association of depression and cardiovascular disorder (CVD), and the increased risk for CVD and due mortality in depressed patients
2010
Interleukine-6 serum levels correlate with response to antidepressant sleep deprivation and sleep phase advance
2002
Differences in interleukins’ patterns between dysthymia and major depression
2001
Immune dysfunction associated with chronic professional stress in nurses
1999
Perceived discrimination and health: A meta-analytic review.
2009 Standout
Neural regulation of innate immunity: a coordinated nonspecific host response to pathogens
2006 Standout
Antidepressant effects of TNF-α blockade in an animal model of depression
2013
Different immune patterns in melancholic and non-melancholic major depression
2001
Chronic inflammation in the etiology of disease across the life span
2019 Standout
Melanin Pigmentation in Mammalian Skin and Its Hormonal Regulation
2004 Standout
Cytokines and depression
2002
Brain-immune interactions and disease susceptibility
2005
Are the Dorsal and Ventral Hippocampus Functionally Distinct Structures?
2010 Standout
Expert Committee Recommendations Regarding the Prevention, Assessment, and Treatment of Child and Adolescent Overweight and Obesity: Summary Report
2007 Standout
Treatment with interferon-alpha (IFNα) of hepatitis C patients induces lower serum dipeptidyl peptidase IV activity, which is related to IFNα-induced depressive and anxiety symptoms and immune activation
2001
Immune activation in non-treated suicidal major depression
1999
Depression and immunity: A meta-analytic review.
1993
Incidence of hypercortisolism and dexamethasone resistance increases with age among wild baboons
1991
Mechanistic explanations how cell-mediated immune activation, inflammation and oxidative and nitrosative stress pathways and their sequels and concomitants play a role in the pathophysiology of unipolar depression
2011
Interleukin-1β and tumor necrosis factor-α in children with major depressive disorder or dysthymia
2002
Inflammation and interleukin-1 signaling network contribute to depressive symptoms but not cognitive decline in old age
2007
The olfactory bulbectomised rat as a model of depression
2005
Cellular Immunity in Depressed, Conduct Disorder, and Normal Adolescents: Role of Adverse Life Events
1994
PLASMA INFLAMMATORY CYTOKINE RESPONSE TO SURGICAL TRAUMA IN CHRONIC DEPRESSED PATIENTS
2001
Endotoxin produces a depressive-like episode in rats
1996
Why is depression bad for the failing heart? a review of the mechanistic relationship between depression and heart failure
2004
Neuroendocrine measures and lymphocyte subsets in depressive illness: Influence of a clinical interview concerning life experiences
1997
Depression is an inflammatory disease, but cell-mediated immune activation is the key component of depression
2010
Variations of lymphocyte subsets associated with stress in depressive populations
1996
Acute phase proteins in major depression
1997
Interleukin 1α (IL-1α) induced activation of p38 mitogen-activated protein kinase inhibits glucocorticoid receptor function
2003
Th1, Th2, and Th3 cytokine alterations in major depression
2005
The inflammatory response system and the availability of plasma tryptophan in patients with primary sleep disorders and major depression
1998
Inflammatory Proteins and Depression in the Elderly
2003
Significantly increased expression of T-cell activation markers (interleukin-2 and HLA-DR) in depression: Further evidence for an inflamatory process during that illness
1993
Life’s Essential 8: Updating and Enhancing the American Heart Association’s Construct of Cardiovascular Health: A Presidential Advisory From the American Heart Association
2022 Standout
Depression, comorbidities and the TNF-α system
2008
When Not Enough Is Too Much: The Role of Insufficient Glucocorticoid Signaling in the Pathophysiology of Stress-Related Disorders
2003
The inflammatory & neurodegenerative (I&ND) hypothesis of depression: leads for future research and new drug developments in depression
2008
Immunoendocrine aspects of major depression
1995
Increased Depressive Ratings in Patients With Hepatitis C Receiving Interferon-α–Based Immunotherapy Are Related to Interferon-α–Induced Changes in the Serotonergic System
2002
The etiology of poststroke depression: a review of the literature and a new hypothesis involving inflammatory cytokines
2006
Social Relationships and Mortality Risk: A Meta-analytic Review
2010 Standout
Antioxidative enzyme activities and lipid peroxidation in major depression: alterations by antidepressant treatments
2001
Plasma Interleukin-18 Levels in Patients With Psychiatric Disorders
2002
Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies
2013 Standout
The evolutionary significance of depression in Pathogen Host Defense (PATHOS-D)
2012
Α Review on the Acute Phase Response in Major Depression
1993
Acute Stressors and Cortisol Responses: A Theoretical Integration and Synthesis of Laboratory Research.
2004 Standout
Progression to AIDS, a clinical AIDS condition and mortality: psychosocial and physiological predictors
2002
Inflammatory markers and depressed mood in older persons: results from the health, aging and body composition study
2003
Glucocorticoid receptors in major depression: relevance to pathophysiology and treatment
2001
Risk factors for suicidal thoughts and behaviors: A meta-analysis of 50 years of research.
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Higher Than Normal Plasma Interleukin-6 Concentrations in Cancer Patients With Depression: Preliminary Findings
2001
Depression in Heart Failure
2006 Standout
Physiological stress in ecology: lessons from biomedical research
2004 Standout
Depression, stress and immunological activation: The role of cytokines in depressive disorders
1998
Interleukin-6-(IL-6) plasma levels in depression and schizophrenia: comparison between the acute state and after remission
1997
Stress and the inflammatory response: A review of neurogenic inflammation
2002
Cytokines, stress, and depressive illness
2002
The role of IL-12 and TGF-β1 in the pathophysiology of major depressive disorder
2006
Stress and the brain: from adaptation to disease
2005 Standout
The plasma levels of interleukin-12 in schizophrenia, major depression, and bipolar mania: effects of psychotropic drugs
2002
Cytokines as mediators of depression: What can we learn from animal studies?
2005
Immune system to brain signaling: Neuropsychopharmacological implications
2011
Immune Correlates of Depression
1999
Beyond diathesis stress: Differential susceptibility to environmental influences.
2009 Standout
Depression, Distress, Lymphocyte Subsets, and Human Immunodeficiency Virus Symptoms on Two Occasions in HIV-Positive Homosexual Men
1991
Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC
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Differential modulation of cytokine production in major depressive disorder by cortisol and dexamethasone
2008
Cytokine-to-brain communication: A review & analysis of alternative mechanisms
1995
Depressive symptoms in patients with chronic hepatitis C are correlated with elevated plasma levels of interleukin-1β and tumor necrosis factor-α
2007
Increased 24‐hour urinary cortisol excretion in patients with post‐traumatic stress disorder and patients with major depression, but not h patients with fibromyalgia
1998
Dyadic Relationship Conflict, Gender, and Mortality in Urban Hemodialysis Patients
2000
The Relationship of Depression and Stressors to Immunological Assays: A Meta-Analytic Review
2001
The stress system in the human brain in depression and neurodegeneration
2005
Indicators of immune activation in major depression
1996
A prospective evaluation of the directionality of the depression–inflammation relationship
2009
Major Depressive Disorder
2008 Standout
Major Depression and Activation of The Inflammatory Response System
1999
Inflammatory markers in major depression and melancholia
2001
Increased neopterin and interferon-gamma secretion and lower availability of L-tryptophan in major depression: Further evidence for an immune response
1994
NLRP3 Inflammasome Mediates Chronic Mild Stress-Induced Depression in Mice via Neuroinflammation
2015
Stress-induced immune dysfunction: implications for health
2005 Standout
Effect of Duloxetine on Pain, Function, and Quality of Life Among Patients With Chemotherapy-Induced Painful Peripheral Neuropathy
2013 Standout
The cyclooxygenase-2 inhibitor celecoxib has therapeutic effects in major depression: results of a double-blind, randomized, placebo controlled, add-on pilot study to reboxetine
2006
Increased plasma concentrations of interleukin-6, soluble interleukin-6, soluble interleukin-2 and transferrin receptor in major depression
1995
Depression, Inflammation, and Incident Cardiovascular Disease in Women With Suspected Coronary Ischemia
2007
Inflammatory and oxidative and nitrosative stress pathways underpinning chronic fatigue, somatization and psychosomatic symptoms
2008
Low Bone Mass in Premenopausal Women With Depression
2007
The immune-mediated alteration of serotonin and glutamate: towards an integrated view of depression
2007
The psychoneuroimmuno-pathophysiology of cytokine-induced depression in humans
2002
Depressive symptoms and inflammation among heart failure patients
2005
Plasma-soluble interleukin-2 and transferrin receptor in schizoprenia and major depression
1995
Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour
2012 Standout
Interleukin-6, a mental cytokine
2011
The new ‘5-HT’ hypothesis of depression: Cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression
2010
A review on the oxidative and nitrosative stress (O&NS) pathways in major depression and their possible contribution to the (neuro)degenerative processes in that illness
2010 Standout
Depressive disorders and immunity: 20 years of progress and discovery
2007
Psychological Stress and the Human Immune System: A Meta-Analytic Study of 30 Years of Inquiry.
2004 Standout
Successful Antidepressant Therapy Restores the Disturbed Interplay Between TNF-α System and HPA Axis
2006
Relation of C-reactive protein to stroke, cognitive disorders, and depression in the general population: systematic review and meta-analysis
2005
Acute-Phase Proteins and Other Systemic Responses to Inflammation
1999 Standout
Targeting abnormal neural circuits in mood and anxiety disorders: from the laboratory to the clinic
2007 Standout
Interleukin-6 and the soluble IL-6 receptor are decreased in cerebrospinal fluid of geriatric patients with major depression: no alteration of soluble gp130
1999
From inflammation to sickness and depression: when the immune system subjugates the brain
2007 Standout
Health outcomes of bereavement
2007 Standout
If it goes up, must it come down? Chronic stress and the hypothalamic-pituitary-adrenocortical axis in humans.
2007 Standout
Allergy is associated with suicide completion with a possible mediating role of mood disorder - a population-based study
2010
The molecular neurobiology of depression
2008 StandoutNature
Can we vaccinate against depression?
2012
The role of childhood trauma in the neurobiology of mood and anxiety disorders: preclinical and clinical studies
2001 Standout
Early parental loss and salivary cortisol in young adulthood: The moderating role of family environment
2006
Depression as a risk factor for the onset of type 2 diabetes mellitus. A meta-analysis
2006
The Intestinal Microbiota Affect Central Levels of Brain-Derived Neurotropic Factor and Behavior in Mice
2011 Standout
Cytokine imbalance in the pathophysiology of major depressive disorder
2007
Clinically Significant Drug Interactions with Newer Antidepressants
2011
Physiology of β-endorphins. A close-up view and a review of the literature
1993
The role of inflammatory mediators in the biology of major depression: central nervous system cytokines modulate the biological substrate of depressive symptoms, regulate stress-responsive systems, and contribute to neurotoxicity and neuroprotection
1999
Acute phase proteins in schizophrenia, mania and major depression: modulation by psychotropic drugs
1997
The role of inflammation in depression: from evolutionary imperative to modern treatment target
2015 Standout
Dipeptidyl-Peptidase IV from Bench to Bedside: An Update on Structural Properties, Functions, and Clinical Aspects of the Enzyme DPP IV
2003
Cytokine-effects on glucocorticoid receptor function: Relevance to glucocorticoid resistance and the pathophysiology and treatment of major depression
2006
Guidelines for the Treatment of Hypothyroidism: Prepared by the American Thyroid Association Task Force on Thyroid Hormone Replacement
2014 Standout
Comparison of Immunological and Endocrinological Markers Associated with Major Depression
2003
Influence of perceived psychological stress and distress on antibody response to low dose rDNA hepatitis B vaccine
1993
A relação entre a função tireoidiana e a depressão: uma revisão
2004
Role of serotonergic and noradrenergic systems in the pathophysiology of depression and anxiety disorders
2000
Current concepts in the diagnosis and management of cytokine release syndrome
2014 Standout
Pharmacological interventions for somatoform disorders in adults
2014 Standout
Sex and depression
1998
Cerebrospinal fluid interleukin (IL)-6 in unipolar major depression
2003
Depression and Coronary Heart Disease
2008 Standout
Association between decreased serum tryptophan concentrations and depressive symptoms in cancer patients undergoing cytokine therapy
2002
Current and Potential Drugs for Treatment of Obesity
1999
Microglia Function in the Central Nervous System During Health and Neurodegeneration
2017 Standout
Levels of Serum Interleukin (IL)-6, IL-1β, Tumour Necrosis Factor-α and Leptin and Their Correlation in Depression
2007
Lower serum zinc in major depression is a sensitive marker of treatment resistance and of the immune/inflammatory response in that illness
1997
Psychoneuroimmunology Meets Neuropsychopharmacology: Translational Implications of the Impact of Inflammation on Behavior
2011
How Do Glucocorticoids Influence Stress Responses? Integrating Permissive, Suppressive, Stimulatory, and Preparative Actions*
2000 Standout
Risky families: Family social environments and the mental and physical health of offspring.
2002 Standout
Vulnerability to psychopathology: A biosocial model.
1999
Lower whole blood glutathione peroxidase (GPX) activity in depression, but not in myalgic encephalomyelitis / chronic fatigue syndrome: another pathway that may be associated with coronary artery disease and neuroprogression in depression.
2011
Increased serum soluble CD8 or suppressor/cytotoxic antigen concentrations in depression: Suppressive effects of glucocorticoids
1996
Depressive symptoms and production of proinflammatory cytokines by peripheral blood mononuclear cells stimulated in vitro
2006
Plasma cytokine profiles in depressed patients who fail to respond to selective serotonin reuptake inhibitor therapy
2006
PSYCHOSOCIAL FACTORS AND CARDIOVASCULAR DISEASES
2005
Cortisol synthesis inhibition: A new treatment strategy for the clinical and endocrine manifestations of depression
1995
Stress, glucocorticoids, and aging
1992
Depression, Medical Illness, and Interleukin-1β in Older Cardiac Patients
2001
The cytokine hypothesis of depression: inflammation, oxidative & nitrosative stress (IO&NS) and leaky gut as new targets for adjunctive treatments in depression.
2008
Works of E. Suy being referenced
Cortisol escape from suppression by dexamethasone during depression is strongly predicted by basal cortisol hypersecretion and increasing age combined
1991
An augmented escape of β-endorphins to suppression by dexamethasone in severely depressed patients
1990
Autoimmunity in depression: increased antiphospholipid autoantibodies
1993
Coexisting dysregulations of both the sympathoadrenal system and hypothalamic-pituitary-adrenal-axis in melancholia
1991
Seasonality in severity of depression: relationships to suicide and homicide occurrence
1993
Sleep disorders and anxiety as symptom profiles of sympathoadrenal system hyperactivity in major depression
1993
Decreased serum dipeptidyl peptidase IV activity in major depression
1991
Immune Disturbances during Major Depression: Upregulated Expression of Interleukin-2 Receptors
1990
A multivariate study of simultaneous escape from suppression by dexamethasone of urinary free cortisol, plasma cortisol, adrenocorticotropic hormone and β‐endorphin in melancholic patients
1991
Effects of dexamethasone on the availability of l-tryptophan and on the insulin and FFA concentrations in unipolar depressed patients
1990
Impaired Lymphocyte Stimulation by Mitogens in Severely Depressed Patients
1989
An evaluation of basal hypothalamic-pituitary-thyroid axis function in depression: Results of a large-scaled and controlled study
1993
Relationships between interleukin-6 activity, acute phase proteins, and function of the hypothalamic-pituitary-adrenal axis in severe depression
1993
Evidence for a systemic immune activation during depression: results of leukocyte enumeration by flow cytometry in conjunction with monoclonal antibody staining
1992
Abnormal pituitary function during melancholia: Reduced α-melanocyte-stimulating hormone secretion and increased intact ACTH non-suppression
1991
The relationships between the availability ofL-tryptophan to the brain, the spontaneous HPA-axis activity, and the HPA-axis responses to dexamethasone in depressed patients
1991
Prediction of the DST results in depressives by means of urinary-free cortisol excretion, dexamethasone levels, and age
1990
Suppressant effects of dexamethasone on the availability of plasma L‐tryptophan and tyrosine in healthy controls and in depressed patients
1990
Immune cell parameters in severely depressed patients: negative findings
1989
Disturbances in acute phase plasma proteins during melancholia: Additional evidence for the presence of an inflammatory process during that illness
1992
Sex-related differences in the relationships between self-rated depression and biological markers
1988
Depression‐related disturbances in mitogen‐induced lymphocyte responses and interleukin‐1β and soluble interleukin‐2 receptor production
1991
Lower angiotensin I converting enzyme activity in melancholic subjects: A pilot study
1992
A further exploration of the relationships between immune parameters and the HPA-axis activity in depressed patients
1991
Relationships between lower plasma L-tryptophan levels and immune-inflammatory variables in depression
1993
Psychomotor retardation, anorexia, weight loss, sleep disturbances, and loss of energy: Psychopathological correlates of hyperhaptoglobinemia during major depression
1993
Antiphospholipid, antinuclear, epstein-barr and cytomegalovirus antibodies, and soluble interleukin-2 receptors in depressive patients
1991
Absolute Number and Percentage of Circulating Natural Killer, Non-MHC-Restricted T Cytotoxic, and Phagocytic Cells in Unipolar Depression
1994
Prediction of subtype and severity of depression by means of dexamethasone suppression test, l-tryptophan: Competing amino acid ratio and MHPG flow
1987
The renal excretion of xanthurenic acid following L ‐tryptophan loading in depressed patients
1987
HPA-Axis hormones and prolactin responses to dextro-fenfluramine in depressed patients and healthy controls
1991
Interleukin-1 beta: a putative mediator of HPA axis hyperactivity in major depression?
1993
The dexamethasone suppression test, the Hamilton Depression Rating Scale and the DSM-III depression categories
1986
Relationship between the dexamethasone suppression test and the l-tryptophan/competing amino acids ratio in depression
1987
Use of the dexamethasone suppression test in an inpatient setting: A replication and new findings
1989