Citation Impact
Citing Papers
Preferential Generation of Follicular B Helper T Cells from Foxp3 + T Cells in Gut Peyer's Patches
2009 StandoutScienceNobel
Disruption of T helper 2-immune responses in Epstein–Barr virus-induced gene 3-deficient mice
2002
Innate and Adaptive Immunity Cooperate Flexibly to Maintain Host-Microbiota Mutualism
2009 StandoutScienceNobel
Toll Pathway-Dependent Blockade of CD4 + CD25 + T Cell-Mediated Suppression by Dendritic Cells
2003 StandoutScience
Commensal Bifidobacterium promotes antitumor immunity and facilitates anti–PD-L1 efficacy
2015 StandoutScience
IL-23 plays a key role in Helicobacter hepaticus –induced T cell–dependent colitis
2006
Transgenic mice rich in endogenous omega-3 fatty acids are protected from colitis
2006
Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species
2010 StandoutScience
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
Cutting Edge: Chronic Intestinal Inflammation in STAT-4 Transgenic Mice: Characterization of Disease and Adoptive Transfer by TNF- Plus IFN-γ-Producing CD4+ T Cells That Respond to Bacterial Antigens
1999
G Protein-Coupled Receptor 43 Is Essential for Neutrophil Recruitment during Intestinal Inflammation
2009
Aryl Hydrocarbon Receptor-Induced Signals Up-regulate IL-22 Production and Inhibit Inflammation in the Gastrointestinal Tract
2011
Cytokines in inflammatory bowel disease
2014 Standout
Distinct Profiles of Effector Cytokines Mark the Different Phases of Crohn’s Disease
2013
TL1A (TNFSF15) Regulates the Development of Chronic Colitis by Modulating Both T-Helper 1 and T-Helper 17 Activation
2008
The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells
2006 Standout
The anatomical basis of intestinal immunity
1997
Help for cytotoxic-T-cell responses is mediated by CD40 signalling
1998 StandoutNature
Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome
2015 StandoutNature
Colitis-associated cancer: the role of T cells in tumor development
2009
Intestinal homeostasis and its breakdown in inflammatory bowel disease
2011 StandoutNature
Unravelling the pathogenesis of inflammatory bowel disease
2007 StandoutNature
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
2003 StandoutNature
Pathogenesis and therapy of psoriasis
2007 StandoutNature
Regulatory T Cells
2000 StandoutNobel
Lymphotoxin‐α‐deficient and TNF receptor‐I‐deficient mice define developmental and functional characteristics of germinal centers
1997
The Lymphotoxin β Receptor Controls Organogenesis and Affinity Maturation in Peripheral Lymphoid Tissues
1998 Standout
Ustekinumab Induction and Maintenance Therapy in Refractory Crohn's Disease
2012
Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria
2009 Standout
The inhibitory cytokine IL-35 contributes to regulatory T-cell function
2007 StandoutNature
Layers of mutualism with commensal bacteria protect us from intestinal inflammation
2006
The transcription factor IFN regulatory factor–4 controls experimental colitis in mice via T cell–derived IL-6
2008
Predominant pathogenic role of tumor necrosis factor in experimental colitis in mice
1997
Regulation of T-cell apoptosis in inflammatory bowel disease: to die or not to die, that is the mucosal question
2001
Differential regulation of interleukin 17 and interferon production in inflammatory bowel disease
2009
T-cell help for cytotoxic T lymphocytes is mediated by CD40–CD40L interactions
1998 StandoutNature
Human nutrition, the gut microbiome and the immune system
2011 StandoutNature
Differential Activity of IL-12 and IL-23 in Mucosal and Systemic Innate Immune Pathology
2006
A Randomized Trial of Ustekinumab, a Human Interleukin-12/23 Monoclonal Antibody, in Patients With Moderate-to-Severe Crohn's Disease
2008
IL-23 and Th17 cytokines in intestinal homeostasis
2008
Cytokines in autoimmunity
1996
T-bet upregulation and subsequent interleukin 12 stimulation are essential for induction of Th1 mediated immunopathology in Crohn’s disease
2004
Missing Pieces in the NF-κB Puzzle
2002 Standout
Transforming growth factor-β induces development of the TH17 lineage
2006 StandoutNature
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
2001 StandoutNature
PPAR-γ agonists inhibit production of monocyte inflammatory cytokines
1998 StandoutNature
The role of Th1/Th2 polarization in mucosal immunity
2002
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
2005 StandoutNature
Functional interactions between the gut microbiota and host metabolism
2012 StandoutNature
Oxazolone Colitis, a Th2 Colitis Model Resembling Ulcerative Colitis, Is Mediated by IL-13-Producing NK-T Cells
2002
Interleukin-21 enhances T-helper cell type I signaling and interferon-γ production in Crohn’s disease
2005
The TNF-family cytokine TL1A drives IL-13-dependent small intestinal inflammation
2010
TWEAK, a New Secreted Ligand in the Tumor Necrosis Factor Family That Weakly Induces Apoptosis
1997
Th1-type responses mediate spontaneous ileitis in a novel murine model of Crohn’s disease
2001
Inflammatory Skin Disease in K14/p40 Transgenic Mice: Evidence for Interleukin-12-Like Activities of p40
2001
New players in the cytokine orchestra of inflammatory bowel disease
2007
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
1999 StandoutNature
Ligands working as receptors: reverse signaling by members of the TNF superfamily enhance the plasticity of the immune system
2004
PU.1 and Interferon Consensus Sequence-binding Protein Regulate the Myeloid Expression of the Human Toll-like Receptor 4 Gene
2000 StandoutNobel
Immunity, Inflammation, and Cancer
2010 Standout
Constitutive p40 promoter activation and IL-23 production in the terminal ileum mediated by dendritic cells
2003
CD8+ Cytotoxic T Cells Induce Relapsing Colitis in Normal Mice
2006
Caspase-1 processes IFN-γ-inducing factor and regulates LPS-induced IFN- γ production
1997 Nature
CD40 and Its Ligand in Host Defense
1996
Local administration of antisense phosphorothiate olignucleotides to the p65 subunit of NF–κB abrogates established experimental colitis in mice
1996
Taking dendritic cells into medicine
2007 StandoutNatureNobel
Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
1999 StandoutNature
Recognition of Commensal Microflora by Toll-Like Receptors Is Required for Intestinal Homeostasis
2004 Standout
The roles of CCR6 in migration of Th17 cells and regulation of effector T-cell balance in the gut
2009
The changing preference of T and B cells for partners as T‐dependent antibody responses develop
1997
Characteristics of Intestinal Dendritic Cells in Inflammatory Bowel Diseases
2005
Non-canonical inflammasome activation targets caspase-11
2011 StandoutNature
Development of chronic colitis is dependent on the cytokine MIF
2001
RORγ-Expressing Th17 Cells Induce Murine Chronic Intestinal Inflammation via Redundant Effects of IL-17A and IL-17F
2008
Interleukin‐18 overproduction exacerbates the development of colitis with markedly infiltrated macrophages in interleukin‐18 transgenic mice
2003
Cells and Cytokines in the Pathogenesis of Inflammatory Bowel Disease: New Insights from Mouse T Cell Transfer Models
2000
Immune Modulatory Treatment of Trinitrobenzene Sulfonic Acid Colitis with Calcitriol Is Associated with a Change of a T Helper (Th) 1/Th17 to a Th2 and Regulatory T Cell Profile
2007
A microbial symbiosis factor prevents intestinal inflammatory disease
2008 StandoutNature
A central role of CD40 ligand in the regulation of CD4+ T-cell responses
1996
Molecular pathogenesis of inflammatory bowel disease: Genotypes, phenotypes and personalized medicine
2007
Anti–interleukin 12 treatment regulates apoptosis of Th1 T cells in experimental colitis in mice
1999
CCR6 has a non‐redundant role in the development of inflammatory bowel disease
2003
Inflammatory bowel disease: Etiology and pathogenesis
1998 Standout
Regulatory T cells and inflammatory bowel disease
1999
Anti–Interleukin-12 Antibody for Active Crohn's Disease
2004
Tolerance towards resident intestinal flora in mice is abrogated in experimental colitis and restored by treatment with interleukin‐10 or antibodies to interleukin‐12
1996
Selective disruption of lymphotoxin ligands reveals a novel set of mucosal lymph nodes and unique effects on lymph node cellular organization
1997
Cancer-related inflammation
2008 StandoutNature
A phase 1/2A Trial of STA 5326, an oral interleukin-12/23 inhibitor, in patients with active moderate to severe Crohnʼs disease
2006
Proinflammatory Cytokines in the Pathogenesis of Inflammatory Bowel Diseases
2011
The TRAF Family of Signal Transducers Mediates NF-κB Activation by the TRANCE Receptor
1998 StandoutNobel
Interleukin-22, a TH17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis
2006 StandoutNature
Macrophage-derived IL-18–mediated intestinal inflammation in the murine model of Crohn's disease
2001
Neutralization of tumour necrosis factor (TNF) but not of IL-1 reduces inflammation in chronic dextran sulphate sodium-induced colitis in mice
1997
Mice Deficient in Nuclear Factor (NF)-κB/p52 Present with Defects in Humoral Responses, Germinal Center Reactions, and Splenic Microarchitecture
1998
Helicobacter hepaticusTriggers Colitis in Specific-Pathogen-Free Interleukin-10 (IL-10)-Deficient Mice through an IL-12- and Gamma Interferon-Dependent Mechanism
1998
Interleukin-23 drives innate and T cell–mediated intestinal inflammation
2006
Ribosomal Crystallography: Peptide Bond Formation, Chaperone Assistance, and Antibiotics Inactivation
2007 StandoutNobel
Up-Regulation of the IL-12 Receptor β2 Chain in Crohn’s Disease
2000
Repression of B7.2 on Self-reactive B Cells Is Essential to Prevent Proliferation and Allow Fas-mediated Deletion by CD4+ T Cells
1998 StandoutNobel
BAFF, a Novel Ligand of the Tumor Necrosis Factor Family, Stimulates B Cell Growth
1999
T Helper 1 and T Helper 2 Cells Are Pathogenic in an Antigen-specific Model of Colitis
2002
The transition state for formation of the peptide bond in the ribosome
2006 StandoutNobel
Intestinal Bacteria and the Regulation of Immune Cell Homeostasis
2010
Factors Involved in the Differentiation of TGF-β-Producing Cells from Naive CD4+ T Cells: IL-4 and IFN-γ Have Opposing Effects, While TGF-β Positively Regulates Its Own Production
1998
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production
2008 StandoutNature
Commensal Host-Bacterial Relationships in the Gut
2001 StandoutScience
Resident Enteric Bacteria Are Necessary for Development of Spontaneous Colitis and Immune System Activation in Interleukin-10-Deficient Mice
1998
T Cell–mediated Pathology in Two Models of Experimental Colitis Depends Predominantly on the Interleukin 12/Signal Transducer and Activator of Transcription (Stat)-4 Pathway, but Is Not Conditional on Interferon γ Expression by T Cells
1998
Constitutive p40 promoter activation and IL-23 production in the terminal ileum mediated by dendritic cells
2003
An Anti-IL-12p40 Antibody Down-Regulates Type 1 Cytokines, Chemokines, and IL-12/IL-23 in Psoriasis
2006
The Transcription Factor T-bet Regulates Mucosal T Cell Activation in Experimental Colitis and Crohn's Disease
2002
Costimulation via OX40L Expressed by B Cells Is Sufficient to Determine the Extent of Primary CD4 Cell Expansion and Th2 Cytokine Secretion In Vivo
2003
The transcription factor NFATc2 controls IL-6–dependent T cell activation in experimental colitis
2008
Treatment of T Cell-Dependent Experimental Colitis in SCID Mice by Local Administration of an Adenovirus Expressing IL-18 Antisense mRNA
2002
Network of dendritic cells within the muscular layer of the mouse intestine
2005 StandoutNobel
The Immunology of Mucosal Models of Inflammation
2002
Dendritic cells require maturation via CD40 to generate protective antitumor immunity.
1998
A β-oxidation-resistant lipoxin A4analog treats hapten-induced colitis by attenuating inflammation and immune dysfunction
2004
Death Receptors: Signaling and Modulation
1998 StandoutScience
Cytotoxic T lymphocyte antigen-4 (CTLA-4) limits the expansion of encephalitogenic T cells in experimental autoimmune encephalomyelitis (EAE)-resistant BALB/c mice
2002 StandoutNobel
IL-12, but not IFN-gamma, plays a major role in sustaining the chronic phase of colitis in IL-10-deficient mice.
1998
Role of appendix in the development of inflammatory bowel disease in TCR-alpha mutant mice.
1996
Inflammatory Bowel Disease
2010 Standout
TSLP-activated dendritic cells induce an inflammatory T helper type 2 cell response through OX40 ligand
2005
Neutralization of interleukin-18 reduces severity in murine colitis and intestinal IFN-γ and TNF-α production
2001
Fas Preassociation Required for Apoptosis Signaling and Dominant Inhibition by Pathogenic Mutations
2000 StandoutScienceNobel
Cutting edge: chronic intestinal inflammation in STAT-4 transgenic mice: characterization of disease and adoptive transfer by TNF- plus IFN-gamma-producing CD4+ T cells that respond to bacterial antigens.
1999
Oxazolone Colitis: A Murine Model of T Helper Cell Type 2 Colitis Treatable with Antibodies to Interleukin 4
1998
IL-6 Is Required for the Development of Th1 Cell-Mediated Murine Colitis
2000
A Role for NK Cells as Regulators of CD4+ T Cells in a Transfer Model of Colitis
1998
Antibodies Against IL-12 Prevent Superantigen-Induced and Spontaneous Relapses of Experimental Autoimmune Encephalomyelitis
1998
Increased interleukin 12 production in progressive multiple sclerosis: Induction by activated CD4+T cells via CD40 ligand
1997
Regulation of Interleukin (IL)-12 Receptor β2 Subunit Expression by Endogenous IL-12: A Critical Step in the Differentiation of Pathogenic Autoreactive T Cells
1999
Specific Regulation of T Helper Cell 1–mediated Murine Colitis by CEACAM1
2004
CD40 AND CD154 IN CELL-MEDIATED IMMUNITY
1998
PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors
2010 StandoutNobel
IL-23 Production by Cosecretion of Endogenous p19 and Transgenic p40 in Keratin 14/p40 Transgenic Mice: Evidence for Enhanced Cutaneous Immunity
2003
MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands
2010 StandoutNobel
Requirement for CD40 Ligand in Costimulation Induction, T Cell Activation, and Experimental Allergic Encephalomyelitis
1996 Science
Treatment of Murine Colitis by Lactococcus lactis Secreting Interleukin-10
2000 Science
THE INTERLEUKIN-12/INTERLEUKIN-12-RECEPTOR SYSTEM: Role in Normal and Pathologic Immune Responses
1998
Factors involved in the differentiation of TGF-beta-producing cells from naive CD4+ T cells: IL-4 and IFN-gamma have opposing effects, while TGF-beta positively regulates its own production.
1998
An Inherited Disorder of Lymphocyte Apoptosis: The Autoimmune Lymphoproliferative Syndrome
1999
IL-23 is essential for T cell–mediated colitis and promotes inflammation via IL-17 and IL-6
2006
IL-27 Regulates Homeostasis of the Intestinal CD4+ Effector T Cell Pool and Limits Intestinal Inflammation in a Murine Model of Colitis
2009
Biologic therapy for inflammatory bowel disease
1997
Cutting Edge: Dendritic Cells Require Maturation via CD40 to Generate Protective Antitumor Immunity
1998
Compromised Ox40 Function in Cd28-Deficient Mice Is Linked with Failure to Develop Cxc Chemokine Receptor 5–Positive Cd4 Cells and Germinal Centers
1999
Interferon (IFN) Consensus Sequence-binding Protein, a Transcription Factor of the IFN Regulatory Factor Family, Regulates Immune Responses In Vivo through Control of Interleukin 12 Expression
1997
Experimental granulomatous colitis in mice is abrogated by induction of TGF-beta-mediated oral tolerance.
1996
Reciprocal Control of T Helper Cell and Dendritic Cell Differentiation
1999 StandoutScience
Works of E. Stüber being referenced
Putrescine Uptake and Metabolism in Isolated Rat Pancreatic Acini
1992
Blocking the CD40L-CD40 interaction in vivo specifically prevents the priming of T helper 1 cells through the inhibition of interleukin 12 secretion.
1996
Antibodies to interleukin 12 abrogate established experimental colitis in mice.
1995
The T cell-B cell interaction via OX40-OX40L is necessary for the T cell-dependent humoral immune response.
1996