Citation Impact
Citing Papers
A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex.
1996
Chromosome 5 allele loss at the glucocorticoid receptor locus in human colorectal carcinomas
1988
Periampullary adenomas and adenocarcinomas in familial adenomatous polyposis: Cumulative risks and APC gene mutations
2001
Are different events involved in the development of sporadic versus hereditary tumours? The possible importance of the microenvironment in hereditary cancer
1990
Elastin: molecular description and function
1999
Loss of constitutional heterozygosity in colon carcinoma from patients with familial polyposis coli
1988 Nature
Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related gene
1994 StandoutNature
A New Protein Conjugation System in Human
1998 StandoutNobel
Tumor suppressor genes: the p53 and retinoblastoma sensitivity genes and gene products
1990
Ubc9p Is the Conjugating Enzyme for the Ubiquitin-like Protein Smt3p
1997 StandoutNobel
The secretory phospholipase A2 gene is a candidate for the Mom1 locus, a major modifier of ApcMin-induced intestinal neoplasia
1995
A genetic model for colorectal tumorigenesis
1990 Standout
Genetic pathways in colorectal and other cancers
1999
Risks of cancer in BRCA1-mutation carriers
1994 Standout
Colon cancer genetics
1992
Alleles of the APC gene: An attenuated form of familial polyposis
1993
HAPPY mapping of a YAC reveals alternative haplotypes in the human immunoglobulin VHlocus
1993 StandoutNobel
Juvenile polyposis: A case with early presentation and death attributable to adenocarcinoma of the pancreas
1989
Multiple endocrine neoplasia type 1 gene maps to chromosome 11 and is lost in insulinoma
1988 Nature
Reshaping human antibodies for therapy
1988 StandoutNatureNobel
Lessons from Hereditary Colorectal Cancer
1996 Standout
Molecular Diagnosis of Familial Adenomatous Polyposis
1993
Tumor suppressor genes
1991 Standout
Laryngeal carcinoma in a lynch syndrome II kindred
1988
A protein conjugation system essential for autophagy
1998 StandoutNatureNobel
Development of multiple endocrine neoplasia type 2A does not involve substantial deletions of chromosome 10
1989
The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimer
1997
Close linkage of a highly polymorphic marker (D5S37) to familial adenomatous polyposis (FAP) and confirmation of FAP localization on chromosome 5q21-q22
1988
Genetic and Epigenetic Losses of Heterozygosity in Cancer Predisposition and Progression
1990
Structure and polymorphism of human telomere-associated DNA
1990
Amplification of a gene encoding a p53-associated protein in human sarcomas
1992 StandoutNature
Phenotypic variation in colorectal adenoma/cancer expression in two families. Hereditary flat adenoma syndrome
1990
Hereditary Colorectal Cancer
2003 Standout
Molecular themes in oncogenesis
1991 StandoutNobel
Modification of yeast Cdc53p by the ubiquitin-related protein Rub1p affects function of the SCFCdc4 complex
1998
Fibulin-5/DANCE is essential for elastogenesis in vivo
2002 StandoutNatureNobel
Restriction of ocular fundus lesions to a specific subgroup of APC mutations in adenomatous polyposis coli patients
1993
Genes specifically expressed at growth arrest of mammalian cells
1988
Genetic mapping of a second locus predisposing to hereditary non–polyposis colon cancer
1993
MULTIPLE GENETIC ALTERATIONS IN DISTAL AND PROXIMAL COLORECTAL CANCER
1989
Mdm2 Is a RING Finger-dependent Ubiquitin Protein Ligase for Itself and p53
2000
The role of autophagy during the early neonatal starvation period
2004 StandoutNatureNobel
Genetic Alterations during Colorectal-Tumor Development
1988 Standout
UPPER GASTROINTESTINAL CANCER IN PATIENTS WITH FAMILIAL ADENOMATOUS POLYPOSIS
1989
Genetic Analysis of an Inherited Predisposition to Colon Cancer in a Family with a Variable Number of Adenomatous Polyps
1990
Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse
1993
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
A ubiquitin-like system mediates protein lipidation
2000 StandoutNatureNobel
Virus-specific CD8+ T-cell memory determined by clonal burst size
1994 StandoutNatureNobel
Allelic Loss in Colorectal Carcinoma
1989
Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22
1984 Standout
The LDL Receptor Gene: A Mosaic of Exons Shared with Different Proteins
1985 StandoutScienceNobel
Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis
1978 Standout
Differential DNA sequence deletions from chromosomes 3, 11, 13, and 17 in squamous-cell carcinoma, large-cell carcinoma, and adenocarcinoma of the human lung.
1989
The Chronic Myelocytic Cell Line K562 Contains a Breakpoint in bcr and Produces a Chimeric bcr/c-abl Transcript
1986
Loss of constitutional heterozygosity in colorectal tumors from patients with familial polyposis coli and those with nonpolyposis colorectal carcinoma.
1989
Cell-free synthesis and segregation of beta 2-microglobulin.
1979 StandoutNobel
Control of HLA-A,B,C synthesis and expression in interferon-treated cells.
1982 StandoutNobel
Checkpoints: Controls That Ensure the Order of Cell Cycle Events
1989 StandoutScienceNobel
Altering Genotype and Phenotype by DNA-Mediated Gene Transfer
1980 StandoutScienceNobel
Gene losses in human tumours
1988 Nature
An appraisal of the application of recombinant DNA techniques to chromosome defects
1985
Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences
1984 StandoutNature
Production of Specific Antisera to Human B Lymphocytes
1976
Regulation of Receptor Fate by Ubiquitination of Activated β 2 -Adrenergic Receptor and β-Arrestin
2001 StandoutScienceNobel
Amplification of N- myc in Untreated Human Neuroblastomas Correlates with Advanced Disease Stage
1984 StandoutScienceNobel
Extracellular matrix 4: The elastic fiber
1993
Tumor Suppressor Genes: The Puzzle and the Promise
1989 Science
Loss of allelic heterozygosity at a second locus on chromosome 11 in sporadic Wilms' tumor cells.
1989
Role for the Wilms tumor gene in genital development?
1990
The Chromosomal Basis of Human Neoplasia
1983 Science
The Galvanization of Biology: A Growing Appreciation for the Roles of Zinc
1996 StandoutScience
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
The human cellular abl gene product in the chronic myelogenous leukemia cell line K562 has an associated tyrosine protein kinase activity
1985
p53 mutations in colorectal cancer.
1990
Abnormalities in Structure and Expression of the Human Retinoblastoma Gene in SCLC
1988 Science
Diversity of murine gamma genes and expression in fetal and adult T lymphocytes
1986 StandoutNatureNobel
Inheritance of human breast cancer: evidence for autosomal dominant transmission in high-risk families.
1988
Polymorphisms of a human variable heavy chain gene show linkage with constant heavy chain genes.
1984 StandoutNobel
Serological identification of HL-A-linked human ‘Ia-type’ antigens
1975 Nature
Molecular Characterization of the SUMO-1 Modification of RanGAP1 and Its Role in Nuclear Envelope Association
1998
c-sis is translocated from chromosome 22 to chromosome 9 in chronic myelocytic leukemia.
1983
Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A
1986 StandoutNature
Human DNA ligase I cDNA: cloning and functional expression in Saccharomyces cerevisiae.
1990 StandoutNobel
Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms.
1989 Standout
Concerted Nonsyntenic Allelic Loss in Human Colorectal Carcinoma
1988 Science
The N-rasoncogene assigned to the short arm of human chromosome 1
1983
A cellular oncogene (c-Ki-ras) is amplified, overexpressed, and located within karyotypic abnormalities in mouse adrenocortical tumour cells
1983 StandoutNatureNobel
Role of a tumor-suppressor gene in the negative control of anchorage-independent growth of Syrian hamster cells.
1989
Two tandemly organized human genes encoding the T-cell γ constant-region sequences show multiple rearrangement in different T-cell types
1985 Nature
Fused transcript of abl and bcr genes in chronic myelogenous leukaemia
1985 StandoutNature
Molecular structure of human histocompatibility antigens: the HLA‐C series
1977
Evolution of tumours and the impact of molecular oncology
1985 Nature
Localization of the c-abl oncogene adjacent to a translocation break point in chronic myelocytic leukaemia
1983 Nature
Binding of APC to the Human Homolog of the Drosophila Discs Large Tumor Suppressor Protein
1996 Science
An 8-kilobase abl RNA transcript in chronic myelogenous leukemia.
1984
Cell-free translation of the mRNAs for the heavy and light chains of HLA-A and HLA-B antigens.
1979
The Gene for Familial Polyposis Coli Maps to the Long Arm of Chromosome 5
1987 Science
Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia
1985 StandoutScienceNobel
The expression and relation of HLA, β2 ‐microglobulin and receptor for marmoset red blood cells on man/mouse and man/Chinese hamster hybrid cells
1977
Suppression of the Neoplastic Phenotype by Replacement of the RB Gene in Human Cancer Cells
1988 Science
Loss of heterozygosity for the short arm of chromosome 1 in human neuroblastomas: correlation with N-myc amplification.
1989
Translocation of immunoglobulin VH genes in Burkitt lymphoma.
1982
Cloning of the gene and cDNA for mammalian β-adrenergic receptor and homology with rhodopsin
1986 StandoutNatureNobel
Structural Rearrangement of the Retinoblastoma Gene in Human Breast Carcinoma
1988 Science
Cell surface antigens coded for by the human chromosome 7
1976
Lambda lg constant region genes are translocated to chromosome 8 in Burkitt's lymphoma with t(8:22
1983
Normal Development of Mice Deficient in β 2 M, MCClass I Proteins, and CD8 + T Cells
1990 StandoutScienceNobel
Loss of genes on the short arm of chromosome 11 in human lung carcinomas.
1987
Sequence of a human immunoglobulin gamma 3 heavy chain constant region gene: comparison with the other human Cγgenes
1986
Major histocompatibility antigens: The human (HLA-A,-B,-C) and murine (H-2K, H-2D) class I molecules
1981
Cell-surface expression of H-2Db requires N-linked glycans
1987
The Status of the Gene Map of the Human Chromosomes
1977 Science
Chromosome 18 allele loss at the D18S6 locus in human colorectal carcinomas
1988
Tumor Rejection After Direct Costimulation of CD8 + T Cells by B7-Transfected Melanoma Cells
1993 StandoutScienceNobel
Detection and Surveillance of Colorectal Cancer
1990
The Molecular Genetics of Cancer
1987 StandoutScienceNobel
Hu- ets -1 and Hu- ets -2 Genes Are Transposed in Acute Leukemias with (4;11) and (8;21) Translocations
1986 Science
Exposure of K562 cells to anti-receptor monoclonal antibody OKT9 results in rapid redistribution and enhanced degradation of the transferrin receptor.
1986
The Genetic Control of HLA‐A and B Antigens in Somatic Cell Hybrids: Requirement for β2 Microglobulin
1978
Hereditary Nonpolyposis Colorectal Cancer—Lynch Syndromes I and II
1988
Regulation of viral and cellular oncogene expression by cytosine methylation
1983
Translocation joins c-myc and immunoglobulin γ1 genes in a Burkitt lymphoma revealing a third exon in the c-myc oncogene
1983 Nature
Extracolonic manifestations associated with familial adenomatous polyposis.
1990
Protein phosphorylation at tyrosine is induced by the v-erbB gene product in vivo and in vitro
1985
CpG island clones from a deletion encompassing the gene for adenomatous polyposis coli.
1989
c-erbB activation in ALV-induced erythroblastosis: novel RNA processing and promoter insertion result in expression of an amino-truncated EGF receptor
1985
Translocation and Rearrangements of the c- myc Oncogene Locus in Human Undifferentiated B-Cell Lymphomas
1983 Science
Low incidence of loss of chromosome 10 in sporadic and hereditary human medullary thyroid carcinoma.
1989
Identification of transforming gene in two human sarcoma cell lines as a new member of the ras gene family located on chromosome 1
1983 Nature
Translocation of c-abl oncogene correlates with the presence of a Philadelphia chromosome in chronic myelocytic leukaemia
1983 Nature
Oncogene Amplification in Tumor Cells
1986
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
1987 Standout
Apg7p/Cvt2p: A Novel Protein-activating Enzyme Essential for Autophagy
1999 StandoutNobel
Replacing the complementarity-determining regions in a human antibody with those from a mouse
1986 StandoutNatureNobel
A polymorphic DNA marker linked to cystic fibrosis is located on chromosome 7
1985 Nature
The independent expression of HLA and? 2-microglobulin on human-mouse hybrids
1976
ALTERED TRANSCRIPTION OF AN ONCOGENE IN CHRONIC MYELOID LEUKAEMIA
1984
A genetic study of Gardner syndrome and congenital hypertrophy of the retinal pigment epithelium.
1988
Transcriptional activation of the translocated c- myc oncogene in Burkitt lymphoma
1983
Structure and function of telomeres
1991 StandoutNatureNobel
Transcriptional activation of an unrearranged and untranslocated c-myc oncogene by translocation of a C lambda locus in Burkitt.
1983
Chromosomal location of human kappa and lambda immunoglobulin light chain constant region genes
1982
The sequence of a human immunoglobulin epsilon heavy chain constant region gene, and evidence for three non-allelic genes.
1982
Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction
1987 Standout
Enhanced expression of HLA antigens and β2‐microglobulin on interferon‐treated human lymphoid cells
1979
Genetics and biochemistry of collagen binding-triggered glandular differentiation in a human colon carcinoma cell line.
1988
SUMO-1 Modification and Its Role in Targeting the Ran GTPase-activating Protein, RanGAP1, to the Nuclear Pore Complex
1998 StandoutNobel
Molecular cloning of cDNA encoding human interleukin-2 receptor
1984 StandoutNatureNobel
Chromosome 17 Deletions and p53 Gene Mutations in Colorectal Carcinomas
1989 StandoutScience
Allelotype of Colorectal Carcinomas
1989 Science
Multiple Intestinal Neoplasia Caused by a Mutation in the Murine Homolog of the APC Gene
1992 Science
Dimer formation by an N-terminal coiled coil in the APC protein.
1993
Altered nucleotide sequences of a translocated c-myc gene in Burkitt lymphoma
1983 Nature
A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukaemia
1982 Nature
Transcription enhancer identified near the human Cμ immunoglobulin heavy chain gene is unavailable to the translocated c-myc gene in a Burkitt lymphoma
1983 Nature
Works of E. Solomon being referenced
Genetic analysis of colorectal cancer.
1989
The solution structure of the RING finger domain from the acute promyelocytic leukaemia proto-oncoprotein PML.
1995
Chromosomal assignment of seven human genomic DNA sequences associated with restriction fragment length polymorphisms
1986
The human type II collagen gene (COL2A1) assigned to 12q14.3
1986
Expression of human transferrin receptor is controlled by a gene on chromosome 3: Assignment using species specificity of a monoclonal antibody
1982
Assignment of the human locus determining phosphoglycolate phosphatase (PGP) to chromosome 16
1980
Human myosin heavy chain genes assigned to chromosome 17 using a human cDNA clone as probe
1985
PIC 1, a novel ubiquitin-like protein which interacts with the PML component of a multiprotein complex that is disrupted in acute promyelocytic leukaemia.
1996
Chromosome 5 allele loss in human colorectal carcinomas
1987 Nature
Human gene mapping using an X/autosome translocation
1976
Genetic analysis of the 15;17 chromosome translocation associated with acute promyelocytic leukemia.
1983
Localization of the gene for familial adenomatous polyposis on chromosome 5
1987 Nature
A somatic cell hybrid map of the long arm of human chromosome 17, containing the familial breast cancer locus (BRCA1).
1993
Immunochemical analysis of the <i>N</i>-acetyl hexosaminidases in human-mouse hybrids made using a double selective system
1977
Integration of Ecogpt and SV40 early region sequences into human chromosome 17: a dominant selection system in whole cell and microcell human-mouse hybrids.
1983
Chromosomal localisation of the human homologues to the oncogenes erbA and B.
1984
Assignment of the structural gene for the third component of human complement to chromosome 19.
1982
The chromosomal location of T-cell receptor genes and a T cell rearranging gene: possible correlation with specific translocations in human T cell leukaemia.
1985
Chromosomal localization of human cellular homologues of two viral oncogenes
1982 Nature
The β2-microglobulin gene is on chromosome 15 and not in the HL-A region
1975 Nature
THRA1 and D17S183 flank an interval of < 4 cM for the breast-ovarian cancer gene (BRCA1) on chromosome 17q21.
1993
Human elastin gene: new evidence for localization to the long arm of chromosome 7.
1991
A human T-cell antigen receptor beta chain gene maps to chromosome 7.
1984
Immunoglobulin heavy chain genes in humans are located on chromosome 14
1981