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Citing Papers
Computational design of closely related proteins that adopt two well-defined but structurally divergent folds
2020 StandoutNobel
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
2020 Standout
Purification of μ-Calpain by a Novel Affinity Chromatography Approach. NEW INSIGHTS INTO THE MECHANISM OF THE INTERACTION OF THE PROTEASE WITH TARGETS
1995
X-Ray Structure of Acid-Sensing Ion Channel 1–Snake Toxin Complex Reveals Open State of a Na+-Selective Channel
2014 StandoutNobel
Structure of the Hemagglutinin Precursor Cleavage Site, a Determinant of Influenza Pathogenicity and the Origin of the Labile Conformation
1998
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
2018 StandoutNobel
Synthetic Inhibitors of Elastase
1994
Effects of calcium ions on proteolytic processing of HIV‐1 gp160 precursor and on cell fusion
1994 StandoutNobel
Contribution of Proteasomal β-Subunits to the Cleavage of Peptide Substrates Analyzed with Yeast Mutants
1998 Nobel
O-Glycosylation Modulates Proprotein Convertase Activation of Angiopoietin-like Protein 3
2010
Peptidyl (acyloxy)methyl ketones and the quiescent affinity label concept: the departing group as a variable structural element in the design of inactivators of cysteine proteinases
1991
Implication of cysteine proteases calpain, cathepsin and caspase in ischemic neuronal death of primates
2000
A Serpin Shapes the Extracellular Environment to Prevent Influenza A Virus Maturation
2015 StandoutNobel
Mutation in blood coagulation factor V associated with resistance to activated protein C
1994 StandoutNature
Triggering of cyclin degradation in interphase extracts of amphibian eggs by cdc2 kinase
1990 StandoutNatureNobel
Membrane Fusion
2003 StandoutNobel
[24] Multicatalytic endopeptidase complex: Proteasome
1994
Inhibition of Calpain Blocks Platelet Secretion, Aggregation, and Spreading
1999
Serotonin receptors: Subtypes, functional responses and therapeutic relevance
1995
Development and Therapeutic Potential of Calpain Inhibitors
1996
Isolation of a Chinese Hamster Ovary Cell Clone Possessing Decreased µ-Calpain Content and a Reduced Proliferative Growth Rate
1996
Epoxide electrophiles as activity-dependent cysteine protease profiling and discovery tools
2000
Evidence for Participation of a Calpain-like Cysteine Protease in Cell Cycle Progression through Late G1Phase
1997
Crystal Structure of the Hepatitis C Virus NS3 Protease Domain Complexed with a Synthetic NS4A Cofactor Peptide
1996 StandoutNobel
Three-Dimensional Structure of Chymotrypsin Inactivated with (2S)-N-Acetyl-L-alanyl-L-phenylalanyl .alpha.-chloroethane: Implications for the Mechanism of Inactivation of Serine Proteases by Chloroketones
1994
Purification of Active Calpain by Affinity Chromatography on an Immobilized Peptide Inhibitor
1996
Functional Properties of Recombinant Calpain I and of Mutants Lacking Domains III and IV of the Catalytic Subunit
1997
m‐Calpain subunits remain associated in the presence of calcium
1998
Evolutionary families of peptidases
1993
Ca(2+)-activated neutral protease is active in the erythrocyte membrane in its nonautolyzed 80-kDa form.
1994
The structural and energetic basis for high selectivity in a high-affinity protein-protein interaction
2010 StandoutNobel
Molecular Recognition of Protein−Ligand Complexes: Applications to Drug Design
1997 Standout
Molecular orbital studies of enzyme activity: I: Charge relay system and tetrahedral intermediate in acylation of serine proteinases.
1975 StandoutNobel
Activation of factor V during intrinsic and extrinsic coagulation. Inhibition by heparin, hirudin and d -Phe-Pro-Arg-Ch2Cl
1990
Biologically active monomeric and heterodimeric recombinant human calpain I produced using the baculovirus expression system
1996
Purification and Characterisation of Different Active Forms of Pork Trypsin
1973 StandoutNobel
Ubiquitin-lysozyme conjugates. Identification and characterization of an ATP-dependent protease from rabbit reticulocyte lysates.
1986
De Novo-Designed Enzymes as Small-Molecule-Regulated Fluorescence Imaging Tags and Fluorescent Reporters
2014 StandoutNobel
Role of arginine-tRNA in protein degradation by the ubiquitin pathway
1987 StandoutNatureNobel
In situ capture of mu-calpain activation in platelets.
1993
Complete cDNA and derived amino acid sequence of human factor V.
1987
Naloxone-induced reversal of schizophrenic hallucinations
1977
The selective inactivation of thiol proteasesin vitro andin vivo
1984
Cytoskeletal Protein ABP-280 Directs the Intracellular Trafficking of Furin and Modulates Proprotein Processing in the Endocytic Pathway
1997 StandoutNobel
Functional information and the emergence of biocomplexity
2007 StandoutNobel
Contribution of long-range electrostatic interactions to the stabilization of the catalytic transition state of the serine protease subtilisin BPN'
1993
Carbon-13 NMR characterization of the papain adduct formed by peptidyl acyloxy-, aryloxy-, and chloromethyl ketone irreversible inhibitors
1992
Calpain inhibitors as potential treatment for stroke and other neurodegenerative diseases: recent trends and developments
1998
Inactivation of a Serotonin-Gated Ion Channel by a Polypeptide Toxin from Marine Snails
1998 StandoutScienceNobel
Interaction of serotonin and lysergic acid diethylamide (LSD) in the central nervous system
1955
Mapping epitopes and antigenicity by site-directed masking
2006 StandoutNobel
Endorphins: Profound Behavioral Effects in Rats Suggest New Etiological Factors in Mental Illness
1976 StandoutScienceNobel
Ubiquitin-aldehyde: a general inhibitor of ubiquitin-recycling processes.
1987 StandoutNobel
Peptidyl Epoxides: Novel Selective Inactivators of Cysteine Proteases1
1996
Calpain Regulates Actin Remodeling during Cell Spreading
1998
The Calpain System
2003 Standout
Mass spectrometry-based proteomics
2003 StandoutNature
Copper-Catalyzed Synthesis of Mixed Alkyl Aryl Phosphonates
2014 StandoutNobel
Factors Modulating Brain Serotonin Turnover
1968
β-Endorphin: Endogenous Opiate or Neuroleptic?
1977 StandoutScienceNobel
Molecular orbital studies of enzyme activity: catalytic mechanism of serine proteinases.
1976 StandoutNobel
3,4-Dihydroxyphenylalanine and 5-Hydroxytryptophan as Reserpine Antagonists
1957 StandoutNatureNobel
THE RELATIONSHIP BETWEEN THE PENETRATION OF TRYPTAMINE AND 5‐HYDROXYTRYPTAMINE INTO SMOOTH MUSCLE AND THE ASSOCIATED CONTRACTIONS
1967 StandoutNobel
Receptor Binding and Membrane Fusion in Virus Entry: The Influenza Hemagglutinin
2000 Standout
Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
2020 StandoutScience
Engineering Orthogonal Polypeptide GalNAc-Transferase and UDP-Sugar Pairs
2019 StandoutNobel
Control of programmed cyclin destruction in a cell-free system.
1989
The Release of Cytochrome c from Mitochondria: A Primary Site for Bcl-2 Regulation of Apoptosis
1997 StandoutScience
ROLE OF BRAIN SEROTONIN IN RESERPINE ACTION
1957 StandoutNobel
Cleavage motifs of the yeast 20S proteasome β subunits deduced from digests of enolase 1
1998 Nobel
ATP-dependent incorporation of 20S protease into the 26S complex that degrades proteins conjugated to ubiquitin.
1989 StandoutNobel
Ischemic Cell Death in Brain Neurons
1999 Standout
Electrostatic Basis for Enzyme Catalysis
2006 StandoutNobel
Brain Tryptophan Hydroxylation: Dependence on Arterial Oxygen Tension
1973 StandoutScienceNobel
Crystallographic structure studies of an IgG molecule and an Fc fragment
1976 StandoutNatureNobel
5-Hydroxytryptamine in the Circulation of the Dog
1967 StandoutNatureNobel
Circadian Rhythm in Pineal Serotonin: Effect of Monoamine Oxidase Inhibition and Reserpine
1965 StandoutScienceNobel
Serotonin Release as a Possible Mechanism of Reserpine Action
1955 Science
Conformational flexibility in protein molecules
1979 StandoutNatureNobel
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
The effects of 5‐hydroxytryptamine on gastric secretion in anaesthetized dogs
1958 StandoutNobel
Ghrelin is a growth-hormone-releasing acylated peptide from stomach
1999 StandoutNature
The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade
2020
THE UBIQUITIN SYSTEM
1998 StandoutNobel
Structure of the complex formed by bovine trypsin and bovine pancreatic trypsin inhibitor
1973 StandoutNobel
TMPRSS2 and TMPRSS4 Facilitate Trypsin-Independent Spread of Influenza Virus in Caco-2 Cells
2010
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
Synthesis of peptide fluoromethyl ketones and the inhibition of human cathepsin B
1985
Furin: a mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteins
1997
α-Ketocarbonyl Peptides: A General Approach to Reactive Resin-Bound Intermediates in the Synthesis of Peptide Isosteres for Protease Inhibitor Screening on Solid Support
2001 StandoutNobel
Effect of monoclonal antibodies specific for the 28-kDa subunit on catalytic properties of the calpains.
1993
Reversible phosphorylation controls the activity of cyclosome-associated cyclin-ubiquitin ligase.
1995 StandoutNobel
Structure of the complex formed by bovine trypsin and bovine pancreatic trypsin inhibitor
1974 StandoutNobel
Works of E Shaw being referenced
Some Neurophysiological Aspects of Serotonin
1954
Processing of viral glycoproteins by the subtilisin-like endoprotease furin and its inhibition by specific peptidylchloroalkylketones
1994
Iodination of peptidyl chloromethyl ketones for protease affinity labels
1988
The design of peptidyldiazomethane inhibitors to distinguish between the cysteine proteinases calpain II, cathepsin L and cathepsin B
1988
Isolation and characterization of a trypsin-like serine proteinase from the membranes of Walker 256 carcino-sarcoma cells
1983
Identification of histidine 64 in the active site of subtilisin.
1968
Proteolytic cleavage of wild type and mutants of the F protein of human parainfluenza virus type 3 by two subtilisin-like endoproteases, furin and Kex2
1994
Synthesis and properties of Cbz-Phe-Arg-CHN2 (benzyloxycarbonylphenylalanylarginyldiazomethane) as a proteinase inhibitor
1988
A BIOCHEMICAL AND PHARMACOLOGICAL SUGGESTION ABOUT CERTAIN MENTAL DISORDERS
1954
Evaluation of inhibitor constants and alkylation rates for a series of thrombin affinity labels
1985
Inactivation of cathepsin B by active site-directed disulfide exchange. Application in covalent affinity chromatography.
1983
The synthesis and properties of peptidylmethylsulphonium salts with two cationic residues as potential inhibitors of prohormone processing
1988
DIFFERENTIATION BETWEEN RECEPTORS FOR SEROTONIN AND TRYPTAMINE BY MEANS OF THE EXQUISITE SPECIFICITY OF ANTIMETABOLITES
1957
Pseudotrypsin
1969
Reaction of proteasomes with peptidylchloromethanes and peptidyldiazomethanes
1993
Some Serotoninlike Activities of Lysergic Acid Diethylamide
1956 Science
The synthesis of inhibitors for processing proteinases and their action on the Kex2 proteinase of yeast
1993
The inhibition of macrophage protein turnover by a selective inhibitor of thiol proteinases
1980
Peptidyl diazomethyl ketones are specific inactivators of thiol proteinases.
1981
Affinity labelling of the Ca2+-activated neutral proteinase (calpain) in intact human platelets
1993
The synthesis of lysylfluoromethanes and their properties as inhibitors of trypsin, plasmin and cathepsin B
1987
Investigation of the role of calpain as a stimulus-response mediator in human platelets using new synthetic inhibitors
1991
Peptidyl sulfonium salts. A new class of protease inhibitors.
1988
Synthesis and properties of peptidyl derivatives of arginylfluoromethanes
1988
Inactivation of prolyl endopeptidase by a peptidylchloromethane. Kinetics of inactivation and identification of sites of modification
1991
The synthesis of peptidylfluoromethanes and their properties as inhibitors of serine proteinases and cysteine proteinases
1986
Peptidyldiazomethanes. A novel mechanism of interaction with prolyl endopeptidase
1992
Cofactor dependence of factor Xa incorporation into the prothrombinase complex.
1981
SOME ANTIMETABOLITES OF SEROTONIN AND THEIR POSSIBLE APPLICATION TO THE TREATMENT OF HYPERTENSION
1952
Influenza virus hemagglutinin with multibasic cleavage site is activated by furin, a subtilisin-like endoprotease.
1992
Synthesis of lysine-containing sulphonium salts and their properties as proteinase inhibitors
1988