Citation Impact
Citing Papers
Switching from Repression to Activation: MicroRNAs Can Up-Regulate Translation
2007 StandoutScience
Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
2002 Standout
Neuronal apoptosis linked to EglN3 prolyl hydroxylase and familial pheochromocytoma genes: Developmental culling and cancer
2005 StandoutNobel
Analysis of 148 kb of Genomic DNA Around thewnt1Locus ofFugu rubripes
1999 StandoutNobel
Identification of receptors and Smad proteins involved in activin signalling in a human epidermal keratinocyte cell line
1998
Regulation of Clusterin Gene Expression by Transforming Growth Factor β
1997
Tumor suppressor genes on chromosome 3p involved in the pathogenesis of lung and other cancers
2002
Human Smad3 and Smad4 Are Sequence-Specific Transcription Activators
1998
TGF-β inhibits p70 S6 kinase via protein phosphatase 2A to induce G1 arrest
2000
Involvement of the p38 Mitogen-activated Protein Kinase Pathway in Transforming Growth Factor-β-induced Gene Expression
1999
Role of Transforming Growth Factor β in Human Disease
2000 Standout
PAX3 and PAX7 exhibit conserved cis-acting transcription repression domains and utilize a common gain of function mechanism in alveolar rhabdomyosarcoma
1999
Mechanisms of TGF-β Signaling from Cell Membrane to the Nucleus
2003 Standout
Molecular mechanisms of epithelial–mesenchymal transition
2014 Standout
Dual role of the Smad4/DPC4 tumor suppressor in TGFβ-inducible transcriptional complexes
1997
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
A Mechanism for Regulating Pulmonary Inflammation and Fibrosis: The Integrin αvβ6 Binds and Activates Latent TGF β1
1999 Standout
Phosphorylation of Ser465 and Ser467 in the C Terminus of Smad2 Mediates Interaction with Smad4 and Is Required for Transforming Growth Factor-β Signaling
1997
DNA sequence of the translocation breakpoints in undifferentiated embryonal sarcoma arising in mesenchymal hamartoma of the liver harboring the t(11;19)(q11;q13.4) translocation
2007
TGF-β signaling in tumor suppression and cancer progression
2001 Standout
TGF-β signalling from cell membrane to nucleus through SMAD proteins
1997 StandoutNature
A cytokine-mediated link between innate immunity, inflammation, and cancer
2007 Standout
Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure
2003 Standout
Smad-dependent and Smad-independent pathways in TGF-β family signalling
2003 StandoutNature
Temporal Gene Regulation During HIV-1 Infection of Human CD4+ T Cells
2001
Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling
1997 StandoutNature
Crystal structure of Pseudomonas fluorescens 4-hydroxyphenylpyruvate dioxygenase: an enzyme involved in the tyrosine degradation pathway
1999
Smad6 inhibits signalling by the TGF-β superfamily
1997 Nature
Pressure-independent enhancement of cardiac hypertrophy in natriuretic peptide receptor A–deficient mice
2001 StandoutNobel
Pax7 Is Required for the Specification of Myogenic Satellite Cells
2000 Standout
A single missense mutant of Smad3 inhibits activation of both Smad2 and Smad3, and has a dominant negative effect on TGF‐β signals
1998
The Hedgehog and Wnt signalling pathways in cancer
2001 StandoutNature
MicroRNAs: Target Recognition and Regulatory Functions
2009 Standout
Stem cells find their niche
2001 StandoutNature
Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3
2017 StandoutNatureNobel
NFIB is a potential target for estrogen receptor‐negative breast cancers
2011
A combined syndrome of juvenile polyposis and hereditary haemorrhagic telangiectasia associated with mutations in MADH4 ( SMAD4)
2004 Standout
Smad2 transduces common signals from receptor serine–threonine and tyrosine kinases
1998
Phosphorylation by Casein Kinase I Promotes the Turnover of the Mdm2 Oncoprotein via the SCFβ-TRCP Ubiquitin Ligase
2010 StandoutNobel
Developmental regulation of the growth plate
2003 StandoutNature
HIV-1 Integration in the Human Genome Favors Active Genes and Local Hotspots
2002 Standout
Blinded by the Light: The Growing Complexity of p53
2009 Standout
Combinatorial signaling through BMP receptor IB and GDF5: shaping of the distal mouse limb and the genetics of distal limb diversity
2000
TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4
1997
TGFβ in Cancer
2008 Standout
Smad3 Mutant Mice Develop Metastatic Colorectal Cancer
1998
Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta
1999
Role of Transforming Growth Factor-beta Signaling in Cancer
2000
Physical and Functional Interaction of SMADs and p300/CBP
1998
let-7 Regulates Self Renewal and Tumorigenicity of Breast Cancer Cells
2007 Standout
Idiopathic pulmonary fibrosis
2011 Standout
Regulating the p53 pathway: in vitro hypotheses, in vivo veritas
2006
SMADs: mediators and regulators of TGF-β signaling
1998
TGFβ Signaling in Growth Control, Cancer, and Heritable Disorders
2000 Standout
Mads and Smads in TGFβ signalling
1998
Extracellular Matrix-Associated Transforming Growth Factor-β: Role in Cancer Cell Growth and Invasion
1998
TβRI Phosphorylation of Smad2 on Ser465 and Ser467 Is Required for Smad2-Smad4 Complex Formation and Signaling
1997
Characterization of Human FAST-1, a TGFβ and Activin Signal Transducer
1998
Transforming Growth Factor β Signal Transducer Smad2 Is Expressed in Mouse Meiotic Germ Cells, Sertoli Cells, and Leydig Cells During Spermatogenesis1
1999
Endothelial-to-mesenchymal transition contributes to cardiac fibrosis
2007 Standout
Cell Signaling by Receptor Tyrosine Kinases
2000 Standout
starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein–RNA interaction networks from large-scale CLIP-Seq data
2013 Standout
Negative Regulation of Myofibroblast Differentiation by PTEN (Phosphatase and Tensin Homolog Deleted on Chromosome 10)
2005
TGF-β SIGNAL TRANSDUCTION
1998 Standout
Short-Chain Fatty Acids and Human Colonic Function: Roles of Resistant Starch and Nonstarch Polysaccharides
2001 Standout
Impaired TGF-β Responses in Peripheral T Cells of Gαi2−/− Mice
2005 StandoutNobel
Molecular Physiology of P2X Receptors
2002 Standout
Nonimmunoglobulin target loci of activation-induced cytidine deaminase (AID) share unique features with immunoglobulin genes
2012 StandoutNobel
Lack of a role for transforming growth factor-β in cytotoxic T lymphocyte antigen-4-mediated inhibition of T cell activation
2001 StandoutNobel
The L3 loop: a structural motif determining specific interactions between SMAD proteins and TGF-beta receptors
1998
Transforming Growth Factor (TGF-β)-specific Signaling by Chimeric TGF-β Type II Receptor with Intracellular Domain of Activin Type IIB Receptor
1997
Temporal Gene Regulation During HIV-1 Infection of Human CD4+T Cells
2001
A quantitative analysis of signal transduction from activin receptor to nucleus and its relevance to morphogen gradient interpretation
1999 StandoutNobel
Transforming growth factor β-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells
1997
Dioxygen Activation at Mononuclear Nonheme Iron Active Sites: Enzymes, Models, and Intermediates
2004 Standout
The hereditary renal cell carcinoma 3;8 translocation fuses FHIT to a patched- related gene, TRC8
1998
Expression of P2X7 purinoceptors on human lymphocytes and monocytes: evidence for nonfunctional P2X7 receptors
2000
Signal Transduction by the TGF-β Superfamily
2002 StandoutScience
Control of stem cell self-renewal and differentiation by the heterochronic genes and the cellular asymmetry machinery in Caenorhabditis elegans
2015 StandoutNobel
Specific Activation of Smad1 Signaling Pathways by the BMP7 Type I Receptor, ALK2
1998
Myostatin Inhibits Myoblast Differentiation by Down-regulating MyoD Expression
2002 Standout
Targeted Disruption of Smad3 Reveals an Essential Role in Transforming Growth Factor β-Mediated Signal Transduction
1999
The regulation of genes and genomes by small RNAs
2007 StandoutNobel
Failure of egg cylinder elongation and mesoderm induction in mouse embryos lacking the tumor suppressor smad2
1998
A mechanism of suppression of TGF–β/SMAD signaling by NF-κB/RelA
2000
TGF-β signalling through the Smad pathway
1997
B-Cell Chronic Lymphocytic Leukemia: A Bird of a Different Feather
1999
Effect of Single-Drug Therapy on Reduction of Left Atrial Size in Mild to Moderate Hypertension
1998
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
2004 Standout
A mechanism of suppression of TGF-beta/SMAD signaling by NF-kappa B/RelA.
2000
Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated by Stress and Inflammation
2001 Standout
Disrupting the Pairing Between let-7 and Hmga2 Enhances Oncogenic Transformation
2007 Science
Alterations in components of the TGF-β superfamily signaling pathways in human cancer
2005
Swift Is a Novel BRCT Domain Coactivator of Smad2 in Transforming Growth Factor β Signaling
2001 StandoutNobel
Integrin α3β1–dependent β-catenin phosphorylation links epithelial Smad signaling to cell contacts
2009
The two faces of transforming growth factor β in carcinogenesis
2003 Standout
Regulation of Wound Healing by Growth Factors and Cytokines
2003 Standout
Works of E. Röijer being referenced
Expression of reciprocal hybrid transcripts of HMGIC and FHIT in a pleomorphic adenoma of the parotid gland.
1997
Promoter swapping between the genes for a novel zinc finger protein and β-catenin in pleiomorphic adenomas with t(3;8)(p21;q12) translocations
1997
Chromosomal localization of three human genes encoding members of the TGF-β superfamily of type I serine/threonine kinase receptors
1998
Assignment<sup>1</sup> of the Smad7 gene (MADH7) to human chromosome 18q21.1 by fluorescence in situ hybridization
1998
Chromosomal localization of three human genes encoding bone morphogenetic protein receptors
1999
Identification of Smad2, a Human Mad-related Protein in the Transforming Growth Factor β Signaling Pathway
1997
Amplification of multiple regions of chromosome 12, including 12q13–15, in chronic lymphocytic leukaemia
1997
Regional assignment of the human 4-hydroxyphenylpyruvate dioxygenase gene (HPD) to 12q24→qter by fluorescence in situ hybridization
1995
Translocation, Deletion/Amplification, and Expression of HMGIC and MDM2 in a Carcinoma ex Pleomorphic Adenoma
2002
Identification of NFIB as recurrent translocation partner gene of HMGIC in pleomorphic adenomas
1998