Citation Impact
Citing Papers
Structures of the CXCR4 Chemokine GPCR with Small-Molecule and Cyclic Peptide Antagonists
2010 StandoutScience
The 2.6 Angstrom Crystal Structure of a Human A 2A Adenosine Receptor Bound to an Antagonist
2008 StandoutScience
Why Are A2B Receptors Low-Affinity Adenosine Receptors? Mutation of Asn273 to Tyr Increases Affinity of Human A2B Receptor for 2-(1-Hexynyl)adenosine
2000
Cardiovascular and Metabolic Alterations in Mice Lacking Both β1- and β2-Adrenergic Receptors
1999 StandoutNobel
Time dependent changes in DA uptake sites, D1 and D2 receptor binding and mRNA after 6-OHDA lesions of the medial forebrain bundle in the rat brain
1995
Differential effects of D1 and D2 dopamine receptor agonists on substantia nigra pars reticulata neurons
1990
Ischemia and reperfusion—from mechanism to translation
2011 Standout
An update on the mechanisms of the psychostimulant effects of caffeine
2007
The locus coeruleus–noradrenergic system: modulation of behavioral state and state-dependent cognitive processes
2003 Standout
Why Are A2BReceptors Low-Affinity Adenosine Receptors? Mutation of Asn273 to Tyr Increases Affinity of Human A2BReceptor for 2-(1-Hexynyl)adenosine
2000
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
Relationship between low‐dose amphetamine‐induced arousal and extracellular norepinephrine and dopamine levels within prefrontal cortex
2002
Presenilins are essential for regulating neurotransmitter release
2009 StandoutNatureNobel
Adenosine receptors and Huntington's disease: implications for pathogenesis and therapeutics
2003
Adenosine Receptors in Health and Disease
2011
Regional differences in the ability of caffeine to affect haloperidol-induced striatal c-fos mRNA expression in the rat
1998
Fluorescent Labeling of Purified β2 Adrenergic Receptor
1995 StandoutNobel
The selective adenosine A2A receptor antagonist SCH 58261 discriminates between two different binding sites for [3H]-CGS 21680 in the rat brain
1996
Caffeine mimics the effect of a dopamine D23 receptor agonist on the expression of immediate early genes in globus pallidus
1997
Are the Dorsal and Ventral Hippocampus Functionally Distinct Structures?
2010 Standout
Delirium in elderly people
2013 Standout
Adenosine receptor agonists: Synthesis and biological evaluation of the diastereoisomers of 2-(3-hydroxy-3-phenyl-1-propyn-1-yl)NECA
1997
Association of dopamine d, and d2 receptors with specific cellular elements in the basal ganglia of the cat: The uneven topography of dopamine receptors in the striatum is determined by intrinsic striatal cells, not nigrostriatal axons
1988
2-Aralkynyl and 2-Heteroalkynyl Derivatives of Adenosine-5'-N-Ethyluronamide as Selective A2a Adenosine Receptor Agonists
1995
Motor stimulant effects of the adenosine A2A receptor antagonist SCH 58261 do not develop tolerance after repeated treatments in 6-hydroxydopamine-lesioned rats
2001
Opposite tonic modulation of dopamine and adenosine on c-fos gene expression in striatopallidal neurons
1999
The olfactory bulbectomised rat as a model of depression
2005
Lack of tolerance to motor stimulant effects of a selective adenosine A2A receptor antagonist
2000
Tissue distribution of adenosine receptor mRNAs in the rat
1996
Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor
2010 StandoutNatureNobel
Dysregulated IP3Signaling in Cortical Neurons of Knock-In Mice Expressing an Alzheimer's-Linked Mutation inPresenilin1Results in Exaggerated Ca2+Signals and Altered Membrane Excitability
2004
Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist
2012 StandoutNatureNobel
Cardiac adrenergic receptor effects of carvedilol
1996
Diverse inotropic effects of 5-hydroxytryptamine in heart muscles of various mammalian species
1996
Lasting increase in D1 dopamine receptors in the lateral part of the substantia nigra pars reticulata after subchronic methamphetamine administration
1991
G Protein-coupled Receptors
1998 StandoutNobel
Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics
1990 StandoutNature
Functional and molecular distinction between recombinant rat GABAA receptor subtypes by Zn2+
1990 StandoutNobel
Adenosine A2A receptor antagonists as new agents for the treatment of Parkinson's disease
1997
Ectonucleotidases CD39 and CD73 on OvCA cells are potent adenosine-generating enzymes responsible for adenosine receptor 2A-dependent suppression of T cell function and NK cell cytotoxicity
2011
Synthesis and Release of Dopamine in Rat Brain: Comparison Between Substantia Nigra Pars Compacta, Pars Reticulata, and Striatum
1989 StandoutNobel
The stimulant effects of caffeine on locomotor behaviour in mice are mediated through its blockade of adenosine A2A receptors
2000
Modulation of GABAA receptor desensitization uncouples sleep onset and maintenance in Drosophila
2008 StandoutNobel
Dopamine D1 Agonist SKF 38393 Increases the State of Phosphorylation of ARPP‐21 in Substantia Nigra
1993 StandoutNobel
The structure and function of G-protein-coupled receptors
2009 StandoutNatureNobel
Adenosine A2A receptor antagonism potentiates l-DOPA-induced turning behaviour and c-fos expression in 6-hydroxydopamine-lesioned rats
1997
Down-regulation of adenosine A2A receptors upon NGF-induced differentiation of PC12 cells
1997
Extracellular adenosine concentrations during in vitro ischaemia in rat hippocampal slices
1999
Molecular modeling of adenosine receptors: new results and trends
2007
Role of D-1 and D-2 receptor stimulation in sensitization to amphetamine-induced circling behavior and in expression and extinction of the Pavlovian conditioned response
1990
Characterization of human A2A adenosine receptors with the antagonist radioligand [3H]‐SCH 58261
1997
Structure of a nanobody-stabilized active state of the β2 adrenoceptor
2011 StandoutNatureNobel
Cyclic AMP‐dependent inhibition of human neutrophil oxidative activity by substituted 2‐propynylcyclohexyl adenosine A2A receptor agonists
2001
Immunohistochemical Localization of Dopamine D Receptors in Rat Retina
1996
Pathoetiological Model of Delirium: a Comprehensive Understanding of the Neurobiology of Delirium and an Evidence-Based Approach to Prevention and Treatment
2008
Memory of Extracellular Adenosine A2A Purinergic Receptor-mediated Signaling in Murine T Cells
1997 StandoutNobel
Dopamine transmission in the initiation and expression of drug- and stress-induced sensitization of motor activity
1991 Standout
Distribution, biochemistry and function of striatal adenosine A2A receptors
1999
Microinjections of Sch-23390 into the ventral tegmental area and substantia nigra pars reticulata attenuate the development of sensitization to the locomotor activating effects of systematic amphetamine
1989
Differential Distribution of β-Adrenergic Receptor Subtypes in Blood Vessels of Knockout Mice Lacking β1-or β2-Adrenergic Receptors
2001 StandoutNobel
Adaptive changes in adenosine receptors following long-term treatment with the adenosine receptor agonist R-phenylisopropyl adenosine
1996
N-Terminal T4 Lysozyme Fusion Facilitates Crystallization of a G Protein Coupled Receptor
2012 StandoutNobel
Review: D1 dopamine receptor—the search for a function: A critical evaluation of the D1/D2 dopamine receptor classification and its functional implications
1987
Adenosine A1-A2A receptor heteromers: new targets for caffeine in the brain
2007
Effects of SCH 58261, an Adenosine A2A Receptor Antagonist, on Quinpirole-Induced Turning in 6-Hydroxydopamine-Lesioned Rats Lack of Tolerance after Chronic Caffeine Intake
2000
Adenosine receptor ligands: differences with acute versus chronic treatment
1996
2-Substituted N-ethylcarboxamidoadenosine derivatives as high-affinity agonists at human A3 adenosine receptors
1999
Differential Regulation of Dopamine D1A Receptor Responsiveness by Various G Protein-coupled Receptor Kinases
1996 StandoutNobel
The diversity of GABAA receptors
1998
Structural Instability of a Constitutively Active G Protein-coupled Receptor
1997 StandoutNobel
Stimulation of adenosine A1 receptors prevents the EEG arousal due to dopamine D1 receptor activation in rabbits
1996
Modulation of forebrain electroencephalographic activity in halothane-anesthetized rat via actions of noradrenergic beta-receptors within the medial septal region.
1996
Synthesis of new pyrazolo[4,3-e]1,2,4-triazolo[1,5-c] pyrimidine and 1,2,3-triazolo[4,5-e]1,2,4-triazolo[1,5-c] pyrimidine displaying potent and selective activity as A2a adenosine receptor antagonists.
1994
Inverse agonist activity of beta-adrenergic antagonists.
1994
Adenosine Receptor Antagonists: Translating Medicinal Chemistry and Pharmacology into Clinical Utility
2008
BindingDB Entry 5256: [(3)H]MRE 3008F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A(3) adenosine receptors.
2012
Functional Uncoupling of Adenosine A2A Receptors and Reduced Response to Caffeine in Mice Lacking Dopamine D2Receptors
2000
Receptors for Purines and Pyrimidines
1998 Standout
Presynaptic and postsynaptic D1 dopamine receptors in the nigrostriatal system of the rat brain: a quantitative autoradiographic study using the selective D1 antagonist [3H]SCH 23390
1987
Potent antagonists for the human adenosine A2B receptor. Derivatives of the triazolotriazine adenosine receptor antagonist ZM241385 with high affinity
1999
Dopamine–Adenosine Interactions in the Striatum and the Globus Pallidus: Inhibition of Striatopallidal Neurons through Either D2or A2AReceptors Enhances D1Receptor-Mediated Effects onc-fosExpression
1997
The Stimulatory Action and the Development of Tolerance to Caffeine Is Associated with Alterations in Gene Expression in Specific Brain Regions
1999
2-Amino-6-furan-2-yl-4-substituted Nicotinonitriles as A2A Adenosine Receptor Antagonists
2008
Aquaporin-4 Water Channel Protein in the Rat Retina and Optic Nerve: Polarized Expression in Müller Cells and Fibrous Astrocytes
1998 StandoutNobel
Localization of dopamine D2 receptor mRNA and D1 and D2 receptor binding in the rat brain and pituitary: an in situ hybridization- receptor autoradiographic analysis
1990
Type I and Type II GABA A -Benzodiazepine Receptors Produced in Transfected Cells
1989 Science
A Family of AMPA-Selective Glutamate Receptors
1990 StandoutScienceNobel
Chromone: A Valid Scaffold in Medicinal Chemistry
2014 Standout
Dopamine autoreceptor antagonists: Effects on sleep-wake activity in the rat
1987 StandoutNobel
Isoquinoline and Quinazoline Urea Analogues as Antagonists for the Human Adenosine A3Receptor
2000
Effects of selective agonists and antagonists for A1 or A2A adenosine receptors on sleep-waking patterns in rats
1996
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
Adenosine A2A receptors induced on iNKT and NK cells reduce pulmonary inflammation and injury in mice with sickle cell disease
2010
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
Actions of Caffeine in the Brain with Special Reference to Factors That Contribute to Its Widespread Use
1999 Standout
Drug Abuse: Hedonic Homeostatic Dysregulation
1997 StandoutScience
Conformational Dynamics of Single G Protein-Coupled Receptors in Solution
2011 StandoutNobel
Reciprocal In Vivo Regulation of Myocardial G Protein–Coupled Receptor Kinase Expression by β-Adrenergic Receptor Stimulation and Blockade
1998 StandoutNobel
Molecular Approach to Adenosine Receptors: Receptor-Mediated Mechanisms of Tissue Protection
2001
Different Effects of Gsα Splice Variants on β2-Adrenoreceptor-mediated Signaling
1998 StandoutNobel
Flip and Flop: A Cell-Specific Functional Switch in Glutamate-Operated Channels of the CNS
1990 StandoutScienceNobel
Receptors for Purines and Pyrimidines
2012 Standout
A2AAdenosine Receptor Deficiency Attenuates Brain Injury Induced by Transient Focal Ischemia in Mice
1999
International Union of Pharmacology. XXV. Nomenclature and Classification of Adenosine Receptors
2001 Standout
Role of A2a Extracellular Adenosine Receptor-Mediated Signaling in Adenosine-Mediated Inhibition of T-Cell Activation and Expansion
1997 StandoutNobel
D 1 and D 2 Dopamine Receptor-regulated Gene Expression of Striatonigral and Striatopallidal Neurons
1990 StandoutScience
The effect of ligand efficacy on the formation and stability of a GPCR-G protein complex
2009 StandoutNobel
Increased baseline occupancy of D 2 receptors by dopamine in schizophrenia
2000 Standout
Water-Soluble Phosphate Prodrugs of 1-Propargyl-8-styrylxanthine Derivatives, A2A-Selective Adenosine Receptor Antagonists
2000
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
A(2A) adenosine receptor deficiency attenuates brain injury induced by transient focal ischemia in mice.
1999
Different Effects of Gsα Splice Variants on β2-Adrenoreceptor-mediated Signaling
1998 StandoutNobel
[3H]MRE 3008F20: A Novel Antagonist Radioligand for the Pharmacological and Biochemical Characterization of Human A3 Adenosine Receptors
2000
Role of A2a Extracellular Adenosine Receptor-Mediated Signaling in Adenosine-Mediated Inhibition of T-Cell Activation and Expansion
1997 StandoutNobel
Modulation of Forebrain Electroencephalographic Activity in Halothane-Anesthetized Rat via Actions of Noradrenergic β-Receptors within the Medial Septal Region
1996
Dopamine-adenosine interactions in the striatum and the globus pallidus: inhibition of striatopallidal neurons through either D2 or A2A receptors enhances D1 receptor-mediated effects on c-fos expression.
1997
Pharmacology of adenosine A2A receptors
1996
Comparison of the vascular effects of adenosine in isolated mouse heart and aorta
2002
Adenosine A2A receptor antagonists as new agents for the treatment of Parkinson's disease
1997
Heteromeric NMDA Receptors: Molecular and Functional Distinction of Subtypes
1992 StandoutScienceNobel
Works of E. Ongini being referenced
Pharmacology of the new selective A2a adenosine receptor agonist 2-hexynyl-5'-N-ethylcarboxamidoadenosine.
1994
Telemetry monitoring of hemodynamic effects induced over time by adenosine agonists in spontaneously hypertensive rats.
1995
Labeling of A2A adenosine receptors in human platelets by use of the new nonxanthine antagonist radioligand [3H]SCH 58261.
1996
D1 dopamine receptors in the rat retina: effect of dark adaptation and chronic blockade by SCH 23390
1987
Interaction of Selected Vasodilating β-Blockers with Adrenergic Receptors in Human Cardiovascular Tissues
1989
Effects of nonsedating histamine H1-antagonists on EEG activity and behavior in the cat
1989
β1 and β2 Adrenoceptors are Involved in Mediating Vasodilation in the Human Coronary Artery
1993
Comparison of CGS 15943, ZM 241385 and SCH 58261 as antagonists at human adenosine receptors
1999
A2A adenosine receptors in human peripheral blood cells
2000
Antagonism of adenosine A2A receptors underlies the behavioural activating effect of caffeine and is associated with reduced expression of messenger RNA for NGFI-A and NGFI-B in caudate–putamen and nucleus accumbens
1997
The D1 dopamine receptor antagonist SCH 23390 enhances REM sleep in the rat
1990
Preferential affinity of 3H-2-oxo-quazepam for type I benzodiazepine recognition sites in the human brain
1988
Effects of selective A1 and A2 adenosine receptor agonists on cardiovascular tissues
1993
Binding affinity of adenosine receptor agonists and antagonists at human cloned A3 adenosine receptors
1998
Role of 5-HT2 receptors in serotonin-induced contraction in the human mammary artery
1990
The non-xanthine heterocyclic compound SCH 58261 is a new potent and selective A2a adenosine receptor antagonist.
1996
Synthesis of imidazo[1,2-c]pyrazolo[4,3-e]pyrimidines, pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidines and 1,2,4-triazolo[5,1-i]purines: new potent adenosine A2 receptor antagonists
1993
Stimulation of dopamine D-1 receptors by SKF 38393 induces EEG desynchronization and behavioral arousal
1985
Presenilin-1 regulates the neuronal threshold to excitotoxicity both physiologically and pathologically
2000
Repeated administration of selective adenosine A1 and A2 receptor agonists in the spontaneously hypertensive rat: tolerance develops to A1-mediated hemodynamic effects.
1994
Current Developments of A2a Adenosine Receptor Antagonists
1995
ChemInform Abstract: Novel N6‐(Substituted‐phenylcarbamoyl)adenosine‐5′‐uronamides as Potent Agonists for A3 Adenosine Receptors.
1996
Pharmacology of adenosine A2A receptors
1996
Differential effects of dopamine D-1 and D-2 receptor antagonist antipsychotics on sleep-wake patterns in the rat.
1993
Effects of selected beta-adrenergic blocking agents on sleep stages in spontaneously hypertensive rats.
1991
In vitro pharmacology of SCH 58261, a new potent and selective A2a adenosine receptor antagonist
1995
6-Hydroxydopamine-induced degeneration of nigral dopamine neurons: Differential effect on nigral and striatal D-1 dopamine receptors
1987
3H-SCH 23390 binding sites in the rat substantia nigra: Evidence for a presynaptic localization and innervation by dopamine
1986
Characterization of Dilevalol Affinity for β- and α-Adrenergic Receptors of Human Cardiovascular Tissues
1988
(E)-1-(Heterocyclyl or cyclohexyl)-2-[1,3,7-trisubstituted (xanthin-8-yl)] ethenes as A2a adenosine receptor antagonists
1996