Citation Impact
Citing Papers
ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation
2009 StandoutScience
C-terminal region of activation-induced cytidine deaminase (AID) is required for efficient class switch recombination and gene conversion
2014 StandoutNobel
Mediation of Poly(ADP-Ribose) Polymerase-1-Dependent Cell Death by Apoptosis-Inducing Factor
2002 StandoutScience
The structure of aconitase
1989
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
2005 StandoutNature
Binding of adenosine diphosphoribosyltransferase to the termini and internal regions of linear DNAs
1989
Mammalian single-strand break repair: Mechanisms and links with chromatin
2006
Loss of poly(ADP-ribose) polymerase-1 causes increased tumour latency in p53-deficient mice
2001
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Chromatin Modifications and Their Function
2007 Standout
A specific, low Km ADP‐ribose pyrophosphatase from rat liver
1989
Poly(ADP-ribose)polymerase: a perplexing participant in cellular responses to DNA breakage
1991
The interaction of Adenosine Diphosphoribosyl Transferase (ADPRT) with a cruciform DNA
1990
Crystal structures of aconitase with isocitrate and nitroisocitrate bound
1992
Poly(ADP-ribose) polymerase interacts with a novel human ubiquitin conjugating enzyme: hUbc9
1997
Protein glycation by ADP-ribose: Studies of model conjugates
1993
Equilibrium model in an in vitro poly(ADP-ribose) turnover system
1995
Nutrient-Sensitive Mitochondrial NAD+ Levels Dictate Cell Survival
2007
An Enzymatic Activity in the Yeast Sir2 Protein that Is Essential for Gene Silencing
1999
Sunburn and p53 in the onset of skin cancer
1994 StandoutNature
Role of poly(ADP-ribose)synthetase in inflammation
1998
Inhibitors and activators of ADP-ribosylation reactions
1994
DNA Damage and Oxygen Radical Toxicity
1988 StandoutScience
Stimulation of the catalytic activity of poly(ADP‐ribosyl) transferase by transcription factor Yin Yang 1
1999
Role of poly(ADP-ribose) formation in DNA repair
1992 StandoutNatureNobel
Role of Glutamic Acid 988 of Human Poly-ADP-ribose Polymerase in Polymer Formation
1995
Cloning and functional expression of poly(ADP‐ribose) polymerase cDNA from Sarcophaga peregrina
1994
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
1995 StandoutNature
Polypeptide domains of ADP-ribosyltransferase obtained by digestion with plasmin
1988
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
2000 StandoutNature
Switching and Signaling at the Telomere
2001 StandoutNobel
Direct stimulation of poly(ADP ribose) polymerase in permeabilized cells by double-stranded DNA oligomers
1991
The mitochondrial permeability transition
1995 Standout
The DNA damage response: putting checkpoints in perspective
2000 StandoutNature
Mode of action of poly(ADP-ribose) glycohydrolase
1994
Evidence for an inhibitory effect exerted by yeast NMN adenylyltransferase on poly(ADP-ribose)polymerase activity
1990
Cellular regulation of ADP-ribosylation of proteins
1991
PolyADP-ribose polymerase is a coactivator for AP-2-mediated transcriptional activation
1999
Poly(ADP-ribose) polymerase and XPF–ERCC1 participate in distinct pathways for the repair of topoisomerase I-induced DNA damage in mammalian cells
2011
Sirtuin activators mimic caloric restriction and delay ageing in metazoans
2004 StandoutNature
Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC
1999 StandoutNature
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
2003 StandoutNature
Expression in Escherichia coli of the 36 kDa domain of poly(ADP-ribose) polymerase and investigation of its DNA binding properties
1993
Role of poly(ADP-ribose) synthetase in inflammation and ischaemia–reperfusion
1998
Molecular and biochemical features of poly (ADP-ribose) metabolism
1993
Repair of and checkpoint response to topoisomerase I-mediated DNA damage
2003
Evidence for the participation of histidine residues located in the 56 kDa C‐terminal polypeptide domain of ADP‐ribosyl transferase in its catalytic activity
1990
Identification of Domains of Poly(ADP-ribose) Polymerase for Protein Binding and Self-association
1995
Amino Acid Metabolism in Mammalian Cell Cultures
1959 StandoutScience
Nuclear ADP-Ribosylation Reactions in Mammalian Cells: Where Are We Today and Where Are We Going?
2006
Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease.
1995
DNA Strand Break-Mediated Partitioning of Poly(ADP-Ribose) Polymerase Function
1994
Amino Acid Sequences Common to Rapidly Degraded Proteins: The PEST Hypothesis
1986 StandoutScience
Biochemical Characterization of Mono(ADP-ribosyl)ated Poly(ADP-ribose) Polymerase
1999
Purification and characterization of poly(ADP-ribose) glycohydrolase. Different modes of action on large and small poly(ADP-ribose).
1986
Cloning of cDNA encoding Drosophila poly(ADP-ribose) polymerase: leucine zipper in the auto-modification domain.
1993
Introduction of fluorine into organic molecules: why and how
1978
ADP-Ribosylation Reactions
1982
Controlling Catenations, Properties and Relative Ring-Component Movements in Catenanes with Aromatic Fluorine Substituents
1997 StandoutNobel
Mössbauer studies of aconitase. Substrate and inhibitor binding, reaction intermediates, and hyperfine interactions of reduced 3Fe and 4Fe clusters.
1985
Effects of altered [ADP-ribose]n metabolism on expression of fetal functions by adult hepatocytes
1982 Nature
Loss of the MYC gene amplified in human HL-60 cells after treatment with inhibitors of poly(ADP-ribose) polymerase or with dimethyl sulfoxide.
1989
Prooxidant States and Tumor Promotion
1985 StandoutScience
The role of hormone receptors and GTP-regulatory proteins in membrane transduction
1980 StandoutNatureNobel
Effect of 3-aminobenzamide on the rate of ligation during repair of alkylated DNA in human fibroblasts.
1983
Activation of a Cytosolic ADP-ribosyltransferase by Nitric Oxide-generating Agents
1989
Poly(ADP-ribose) catabolism in mammalian cells
1994
Agonist-promoted coupling of the beta-adrenergic receptor with the guanine nucleotide regulatory protein of the adenylate cyclase system.
1980 StandoutNobel
The regulatory component of adenylate cyclase. Purification and properties.
1981 StandoutNobel
Cholesterol synthesis in vivo and in vitro in the WHHL rabbit, an animal with defective low density lipoprotein receptors
1983 StandoutNobel
On the Origin of Cancer Cells
1956 StandoutScience
Presence of poly (ADP‐ribose) polymerase and poly (ADP‐ribose) glycohydrolase in the dinoflagellate Crypthecodinium cohnii
1984
Immunofluorescent staining of poly(ADP-ribose) in situ in HeLa cell chromosomes in the M phase.
1981
Cyclic AMP-dependent protein kinase I: Cyclic nucleotide binding, structural changes, and release of the catalytic subunits
1981 StandoutNobel
Membrane Cholesterol, Tumorigenesis, and the Biochemical Phenotype of Neoplasia
1981
Genetic evidence that cholera toxin substrates are regulatory components of adenylate cyclase.
1978
Fluorine in Pharmaceuticals: Looking Beyond Intuition
2007 StandoutScience
(ADP-ribose)n participates in DNA excision repair
1980 StandoutNature
Uncoating ATPase is a member of the 70 kilodalton family of stress proteins
1986 StandoutNobel
Pharmacological and immunohistochemical evidence for a functional nitric oxide synthase system in rat peritoneal eosinophils
1997 StandoutNobel
Mitochondrial Diseases in Man and Mouse
1999 StandoutScience
Induction of Cardiac l-Ornithine Decarboxylase by Nicotinamide and Its Regulation by Putrescine
1978
pH regulation of divalent/monovalent Ca/K cation transport selectivity by a macrocyclic carrier molecule.
1983 StandoutNobel
The Release of Cytochrome c from Mitochondria: A Primary Site for Bcl-2 Regulation of Apoptosis
1997 StandoutScience
Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions
1999 Standout
Nuclear architecture and ultrastructural distribution of poly(ADP-ribosyl)transferase, a multifunctional enzyme
1996
Stereochemistry of the interconversions of citrate and acetate catalyzed by citrate synthase, adenosine triphosphate citrate lyase, and citrate lyase
1971 StandoutNobel
Poly(ADP-ribose) degradation by glycohydrolase starts with an endonucleolytic incision.
1988
ADP-ribosylation of nuclear proteins in mouse testis
1982
Protein Control of Redox Potentials of Iron−Sulfur Proteins
1996 StandoutNobel
Purification of the regulatory component of adenylate cyclase.
1980 StandoutNobel
Iron-Sulfur Clusters: Nature's Modular, Multipurpose Structures
1997 StandoutScience
Differential regulation of S-region hypermutation and class-switch recombination by noncanonical functions of uracil DNA glycosylase
2014 StandoutNobel
Metabolism of Fluorine-Containing Drugs
2001
A23187: A Divalent Cation Ionophore
1972
The production of antibodies to DNA in normal mice following immunization with poly(ADP-ribose).
1986
ADP-ribosylation of the Mr 83,000 stress-inducible and glucose-regulated protein in avian and mammalian cells: modulation by heat shock and glucose starvation.
1983
Poly(ADP-ribose) and ADP-ribosylation of proteins
1976
The energy relay: a proofreading scheme based on dynamic cooperativity and lacking all characteristic symptoms of kinetic proofreading in DNA replication and protein synthesis.
1980 StandoutNobel
Poly(ADP-ribose) may signal changing metabolic conditions to the chromatin of mammalian cells.
1987
Bilirubin Is an Antioxidant of Possible Physiological Importance
1987 StandoutScience
Association of poly(ADP-ribose) polymerase with nuclear subfractions catalyzed with sodium tetrathionate and hydrogene peroxide crosslinks
1996
The guanine nucleotide activating site of the regulatory component of adenylate cyclase. Identification by ligand binding.
1982 StandoutNobel
Enzymatic recycling of clathrin from coated vesicles
1986 StandoutNobel
The Utilization of Carbohydrates by Human Cell Cultures
1958
Poly(ADP-ribose) polymerase stimulates DNA polymerase alpha by physical association.
1993
Cytosolic Ca2+ homeostasis in Ehrlich and Yoshida carcinomas. A new, membrane-permeant chelator of heavy metals reveals that these ascites tumor cell lines have normal cytosolic free Ca2+.
1985 StandoutNobel
Tumor promoter phorbol-12-myristate-13-acetate induces poly(ADP)-ribosylation in fibroblasts.
1985
Adenosine Diphosphoribosylation of Certain Basic Chromosomal Proteins in Isolated Trout Testis Nuclei
1977
Mechanistic Studies on Synthetic Fe−S-Based Clusters and Their Relevance to the Action of Nitrogenases
2005 StandoutNobel
APE1 is dispensable for S-region cleavage but required for its repair in class switch recombination
2014 StandoutNobel
THE UBIQUITIN SYSTEM
1998 StandoutNobel
A new family of mesoporous molecular sieves prepared with liquid crystal templates
1992 Standout
Conformational Adaptability in Enzymes
1973
DNA strand breaks and ADP-ribosyl transferase activation during cell differentiation
1982 Nature
Enzymic studies on ascitic tumors and their host's blood plasmas
1953
Poly(ADP-ribose) polymerase is a catalytic dimer and the automodification reaction is intermolecular.
1993
The interpretation of non-hyperbolic rate curves for two-substrate enzymes. A possible mechanism for phosphofructokinase
1966
Aconitase as Iron−Sulfur Protein, Enzyme, and Iron-Regulatory Protein
1996
Low-Barrier Hydrogen Bonds and Enzymic Catalysis
1994 StandoutScience
Poly(adenosine diphosphate ribose) polymerase activity and nicotinamide adenine dinucleotide in differentiating cardiac muscle
1976
Works of É. Kun being referenced
Prevention of Ca2+ induced cation efflux from liver mitochondria by a cytoplasmic factor and by oligomycin
1971
Apparent Role of Adenosine Diphosphoribosyl Transferase in the Development of Mytilus edulis and the Inhibition of Differentiation by Ligands of the Enzyme Protein
1991
Interaction of a cytoplasmic factor with electron and ion transfer coupled functions of mitochondria
1970
Studies on Specific Enzyme Inhibitors
1964
Control of cation movements in liver mitochondria by a cytoplasmic factor
1971
Studies with Specific Enzyme Inhibitors
1969
Isolation and properties of malic dehydrogenase from ox-heart mitochondria
1957
Cell cycle-dependent intervention by benzamide of carcinogen-induced neoplastic transformation and in vitro poly(ADP-ribosyl)ation of nuclear proteins in human fibroblasts.
1983
Macromolecular association of ADP-ribosyltransferase and its correlation with enzymic activity
1990
Studies on Specific Enzyme Inhibitors
1964
The dependence of oxidative phosphorylation and ATP-ase of liver mitochondria on bound Mg2+
1970
Macromolecular enzymatic product of NAD+ in liver mitochondria.
1975
Regulation of components of the inflammatory response by 5-iodo-6-amino-1,2-benzopyrone, an inhibitor of poly(ADP-ribose) synthetase and pleiotropic modifier of cellular signal pathways
1997
Spectral analysis of the conformation of polyadenosine diphosphoribose. Evidence indicating secondary structure.
1983
Activation of topoisomerase I by poly [ADP-ribose] polymerase.
2000
Prevention of tumorigenesis of oncogene-transformed rat fibroblasts with DNA site inhibitors of poly(ADP ribose) polymerase.
1987
Poly(ADP-ribose) polymerase, a potential target for drugs: Cellular regulatory role of the polymer and the polymerase protein mediated by catalytic and macromolecular colligative actions (Review).
1998
Inactivation of the tricarboxylate carrier of liver mitochondria by (−)-erythrofluorocitrate
1972
Probable helical conformation of poly(ADP-ribose). The effect of cations on spectral properties.
1983
Enzymatic Synthesis of Monofluorocitrate from β-Fluoro-oxaloacetate
1962
Separation and characterization of aconitate hydratase isoenzymes from pig tissues
1971
The in vivo distribution of immunoreactive larger than tetrameric polyadenosine diphosphoribose in histone and non-histone protein fractions of rat liver.
1979
Modification of growth related enzymatic pathways and apparent loss of tumorigenicity of a ras-transformed bovine endothelial cell line by treatment with 5-iodo-6-amino-1,2-benzopyrone (INH2BP)
1996
Covalent modification of proteins by metabolites of NAD+.
1976
Molecular interactions between DNA, poly(ADP-ribose) polymerase, and histones.
1988
Quantitative isolation of oligo- and polyadenosine-diphosphoribosylated proteins by affinity chromatography from livers of normal and dimethylnitrosamine-treated Syrian hamsters. In vivo and in vitro metabolism of the homopolymer.
1981
Studies on the Ehrlich ascites tumor. I. The enzymic and metabolic activities of the ascitic cells and the ascitic plasma.
1951
Age-dependent variation of rates of polyadenosine-diphosphoribose synthesis by cardiocyte nuclei and the lack of correlation of enzymatic activity with macromolecular size distribution of DNA.
1981
Fluorocitrate Inhibition of Aconitase: Relative Configuration of Inhibitory Isomer by X-ray Crystallography
1970 Science
The effect of in vivo treatment with triiodothyronine on the in vitro synthesis of protein-poly(ADP)-ribose adducts by isolated cardiocyte nuclei and the separation of poly(ADP)-ribosylated proteins by phenol extraction and electrophoresis.
1983