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Citing Papers
IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses
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Induction of interferon-stimulated gene expression and antiviral responses require protein deacetylase activity
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Interferon-stimulated transcription: isolation of an inducible gene and identification of its regulatory region.
1986
GAS Elements: A Few Nucleotides with a Major Impact on Cytokine-Induced Gene Expression
1997
Protein ISGylation modulates the JAK-STAT signaling pathway
2003
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
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2002
Analysis of Interferon-Regulated Proteins Binding the Interferon-α-Stimulated Response Element
1998
Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties
1992 StandoutNobel
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2002
IFNs, ISGylation and cancer: Cui prodest?
2012
Regulation of gene expression by cytokines and virus in human cells lacking the type‐I interferon locus
1992
Stat2 Is a Transcriptional Activator That Requires Sequence-specific Contacts Provided by Stat1 and p48 for Stable Interaction with DNA
1997
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2012
Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins
1994 StandoutScience
A transcription factor with SH2 and SH3 domains is directly activated by an interferon α-induced cytoplasmic protein tyrosine kinase(s)
1992
MX2 is an interferon-induced inhibitor of HIV-1 infection
2013 StandoutNatureNobel
Cyclin is a component of maturation-promoting factor from Xenopus
1990 StandoutNobel
Molecular portraits of human breast tumours
2000 StandoutNature
A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
UBP43 (USP18) Specifically Removes ISG15 from Conjugated Proteins
2002
Interferon-induced binding of nuclear factors to promoter elements of the 2-5A synthetase gene.
1988
IFN-λs mediate antiviral protection through a distinct class II cytokine receptor complex
2002 Standout
Identification of Lps2 as a key transducer of MyD88-independent TIR signalling
2003 StandoutNatureNobel
Atg8, a Ubiquitin-like Protein Required for Autophagosome Formation, Mediates Membrane Tethering and Hemifusion
2007 StandoutNobel
Is a p53-Regulated Inhibitor of G2/M Progression
1997
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene
1996 StandoutNatureNobel
Ubiquitin and ubiquitin-like proteins as multifunctional signals
2005
A genetically humanized mouse model for hepatitis C virus infection
2011 StandoutNatureNobel
The Interferon-inducible Ubiquitin-protein Isopeptide Ligase (E3) EFP Also Functions as an ISG15 E3 Ligase
2005
Interferon-stimulated genes and their antiviral effector functions
2011 StandoutNobel
Expressional screening of interferon‐stimulated genes for antiviral activity against hepatitis C virus replication
2006
Complex Modulation of Cell Type-Specific Signaling in Response to Type I Interferons
2006
Genomic response to interferon-α in chimpanzees: Implications of rapid downregulation for hepatitis C kinetics
2006
Interferon-inducible antiviral effectors
2008 Standout
Local and Systemic Effects of Intradermal Recombinant Interferon-γ in Patients with Lepromatous Leprosy
1986 StandoutNobel
Structural patterns in globular proteins
1976 StandoutNatureNobel
Characterization of cloned cDNA representing rat myelin basic protein: Absence of expression in brain of shiverer mutant mice
1983 StandoutNobel
The absence of introns within a human fibroblast interferon gene
1981 StandoutNobel
The long and the short of long–term memory—a molecular framework
1986 StandoutNatureNobel
Transcriptional and posttranscriptional regulation of interferon-induced gene expression in human cells
1984
Proton Magnetic Resonance Study of Ferredoxin from Clostridium pasteurianum
1970 StandoutNobel
Function of Stat2 Protein in Transcriptional Activation by Alpha Interferon
1996
Interferon-induced transcription of a major histocompatibility class I gene accompanies binding of inducible nuclear factors to the interferon consensus sequence.
1988
Poly(A) shortening and degradation of the 3' A+U-rich sequences of human c-myc mRNA in a cell-free system.
1988
The amino-terminal sequence of human fibroblast interferon as deduced from reverse transcripts obtained using synthetic oligonucleotide primers
1980 StandoutNobel
Biosynthesis of transfer RNA in Escherichia coli
1975 StandoutNobel
Combinatorial association and abundance of components of interferon-stimulated gene factor 3 dictate the selectivity of interferon responses.
1995
Purification and in vitro labeling of interferon from a human fibroblastoid cell line.
1978
Transcriptional analyses of interferon-inducible mRNAs.
1987
Intrahepatic Gene Expression during Chronic Hepatitis C Virus Infection in Chimpanzees
2004
Binding of the von Hippel-Lindau Tumor Suppressor Protein to Elongin B and C
1995 StandoutScienceNobel
Active multi-subunit ACh receptor assembled by translation of heterologous mRNA in Xenopus oocytes
1981 StandoutNatureNobel
Purification and cloning of interferon-stimulated gene factor 2 (ISGF2): ISGF2 (IRF-1) can bind to the promoters of both beta interferon- and interferon-stimulated genes but is not a primary transcriptional activator of either.
1990
Identification of the cell multiplication inhibitory factors in interferon preparations as interferons
1976 Nature
Elimination of size and charge heterogeneities of human leukocyte interferons by chemical cleavage
1977
At Least Three Human Type α Interferons: Structure of α2
1980 Science
DNA Microarray Analysis of Chimpanzee Liver during Acute Resolving Hepatitis C Virus Infection
2001
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems
2014 StandoutNobel
Two interferon-induced nuclear factors bind a single promoter element in interferon-stimulated genes.
1988
Human leukocyte and fibroblast interferons are structurally related
1980 Nature
Reexamination of the Role of Ubiquitin-Like Modifier ISG15 in the Phenotype of UBP43-Deficient Mice
2005
Mutant human cells defective in induction of major histocompatibility complex class II genes by interferon gamma.
1993
Induction of the Ly-6A/E gene by interferon alpha/beta and gamma requires a DNA element to which a tyrosine-phosphorylated 91-kDa protein binds.
1993
Mapping of RNA polymerase on mammalian genes in cells and nuclei.
1992
The isolation and amino acid/sugar composition of human fibroblastoid interferon.
1979
A family of structural genes for human lymphoblastoid (leukocyte-type) interferon
1980 Nature
Mouse Interferons: Amino Terminal Amino Acid Sequences of Various Species
1980 Science
Aberrant c-myc RNAs of Burkitt's lymphoma cells have longer half-lives.
1985
Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
1979 Standout
Amino Terminal Sequence of the Major Component of Human Lymphoblastoid Interferon
1980 ScienceNobel
Nucleotide sequence of an avian sarcoma virus oncogene (src) and proposed amino acid sequence for gene product
1980 StandoutNatureNobel
Isolation and in vitro translation of the messenger RNA coding for pancreatic amylase.
1977
Novel Proteinaceous Infectious Particles Cause Scrapie
1982 StandoutScienceNobel
New Protein Sequenator with Increased Sensitivity
1980 Science
Directed transposon Tn5 mutagenesis and complementation analysis of rhizobium meliloti symbiotic nitrogen fixation genes
1982 StandoutNobel
Cytoplasmic activation of ISGF3, the positive regulator of interferon-alpha-stimulated transcription, reconstituted in vitro.
1989
Transcriptional induction by interferon. New protein(s) determine the extent and length of the induction.
1986
Synergistic interaction between interferon-alpha and interferon-gamma through induced synthesis of one subunit of the transcription factor ISGF3.
1990
Interferon-Stimulated Genes: A Complex Web of Host Defenses
2014 StandoutNobel
Positive Regulation of Interferon Regulatory Factor 3 Activation by Herc5 via ISG15 Modification
2010
Interferon-induced nuclear factors that bind a shared promoter element correlate with positive and negative transcriptional control.
1988
Controlling mRNA lifespan
1988 StandoutNatureNobel
Human leukocyte interferon: Isolation and characterization of several molecular forms
1981
c-myc gene is transcribed at high rate in G0-arrested fibroblasts and is post-transcriptionally regulated in response to growth factors
1985 Nature
Posttranscriptional mechanisms are responsible for accumulation of truncated c-myc RNAs in murine plasma cell tumors
1985
Alpha Interferon and Gamma Interferon Stimulate Transcription of a Single Gene through Different Signal Transduction Pathways
1989
Interferon gamma-induced transcription of the high-affinity Fc receptor for IgG requires assembly of a complex that includes the 91-kDa subunit of transcription factor ISGF3.
1993
Structure of the VHL-ElonginC-ElonginB Complex: Implications for VHL Tumor Suppressor Function
1999 StandoutScienceNobel
ISG15, an Interferon-Stimulated Ubiquitin-Like Protein, Is Not Essential for STAT1 Signaling and Responses against Vesicular Stomatitis and Lymphocytic Choriomeningitis Virus
2005
Cloning of the gene and cDNA for mammalian β-adrenergic receptor and homology with rhodopsin
1986 StandoutNatureNobel
The nucleotide sequence of human fibroblast interferon cDNA
1980
Complexity of the early genetic response to growth factors in mouse fibroblasts.
1988
Ribonucleic Acid Maturation in animal Cells
1971
Transcriptional Analyses of Interferon-Inducible mRNAs
1987
Positive regulation of general transcription factor SIII by a tailed ubiquitin homolog.
1995
Inducible high level synthesis of mature human fibroblast interferon inEscherichia coli
1983
Untersuchungen zur Struktur der Ferredoxine
1969
ISGF3, the transcriptional activator induced by interferon alpha, consists of multiple interacting polypeptide chains.
1990
Ube1L and Protein ISGylation Are Not Essential for Alpha/Beta Interferon Signaling
2005
The Molecular Genetics of Cancer
1987 StandoutScienceNobel
Proton Magnetic Resonance, Magnetic Susceptibility and Mössbauer Studies of Clostridium pasteurianum Rubredoxin
1970 StandoutNatureNobel
Interferon response element of the human gene 6-16.
1988
Structure and Properties of a Synthetic Analogue of Bacterial Iron-Sulfur Proteins
1972 StandoutNobel
Activation of Transcription Factors by Interferon-Alpha in a Cell-Free System
1992 Science
Subunit of an alpha-interferon-responsive transcription factor is related to interferon regulatory factor and Myb families of DNA-binding proteins.
1992
Interferon-alpha regulates nuclear translocation and DNA-binding affinity of ISGF3, a multimeric transcriptional activator.
1990
Effect of Interferon-α1 from E. coli on Some Cell Functions
1980 StandoutScienceNobel
Myocardial expression of a constitutively active alpha 1B-adrenergic receptor in transgenic mice induces cardiac hypertrophy.
1994 StandoutNobel
Proteins of transcription factor ISGF-3: one gene encodes the 91-and 84-kDa ISGF-3 proteins that are activated by interferon alpha.
1992
Ferredoxins: Chemistry and Function in Photosynthesis, Nitrogen Fixation, and Fermentative Metabolism
1970
γ-Interferon transcriptionally regulates an early-response gene containing homology to platelet proteins
1985 Nature
Cardiac myocyte hypertrophy is associated with c-myc protooncogene expression.
1986
Human lymphoblastoid interferon. Large scale production and partial purification.
1977 Nobel
A Macrophage Factor Inhibits Adipocyte Gene Expression: An in Vitro Model of Cachexia
1985 StandoutScienceNobel
Physical and genetic characterization of symbiotic and auxotrophic mutants of Rhizobium meliloti induced by transposon Tn5 mutagenesis
1982 StandoutNobel
Heterogeneity of poly(I).poly(C)-induced human fibroblast interferon mRNA species
1980 Nature
Human leukocyte interferon: production, purification to homogeneity, and initial characterization.
1979
Human fibroblast interferon gene lacks introns
1981
pH‐abhängige magnetostatische und spektrale Eigenschaften des oxydierten Ferredoxins aus Clostridium pasterianum
1967
Interferon-Dependent Tyrosine Phosphorylation of a Latent Cytoplasmic Transcription Factor
1992 Science
Interactions of alpha- and gamma-interferon in the transcriptional regulation of the gene encoding a guanylate-binding protein.
1989
Synthesis of human interferon by Xenopus laevis oocytes: two structural genes for interferons in human cells.
1977
NH2-terminal amino acid sequence of human fibroblast interferon.
1980
On the varied biologic effects of interferon
1977
Structure of the Oxidized Form of a Flavodoxin at 2.5-Å Resolution: Resolution of the Phase Ambiguity by Anomalous Scattering
1972
[43] Phosphorylation of Human Immune Interferon (IFN-γ)
1986
Isolation and structure of a human fibroblast interferon gene
1980 Nature
Lipopolysaccharide Stimulates the MyD88-Independent Pathway and Results in Activation of IFN-Regulatory Factor 3 and the Expression of a Subset of Lipopolysaccharide-Inducible Genes
2001
Enhancer-like interferon responsive sequences of the human and murine (2′-5′) oligoadenylate synthetase gene promoters.
1988
Altered molecular species of human interferon produced in the presence of inhibitors of glycosylation.
1977
Overlapping sites for constitutive and induced DNA binding factors involved in interferon-stimulated transcription.
1989
The complete amino acid sequence of human fibroblast interferon as deduced using synthetic oligodeoxyribonucleotide primers of reverse transcriptase
1980 StandoutNobel
Defective Lymphoid Development in Mice Lacking Jak3
1995 StandoutScienceNobel
Biosynthesis of mouse interferon by translation of its messenger RNA in a cell-free system.
1975 StandoutNobel
Isolation of a cDNA cLone Derived from a Blood-Borne Non-A, Non-B Viral Hepatitis Genome
1989 StandoutScienceNobel
Transcription factor ISGF-3 formation requires phosphorylated Stat91 protein, but Stat113 protein is phosphorylated independently of Stat91 protein.
1994
Works of E. Knight being referenced
Human Fibroblast Interferon: Amino Acid Analysis and Amino Terminal Amino Acid Sequence
1980 Science
TURNOVER OF HE LA RIBOSOMAL RNA
1971
ATP-dependent reduction of azide and HCN by N2-fixing enzymes of Azotobacter vinelandii and Clostridium pasteurianum
1967
THE NATURE OF IRON IN FERREDOXIN
1964
IFN-induced 15-kDa protein is released from human lymphocytes and monocytes
1991
Transcriptional induction of two genes in human cells by beta interferon.
1984
Interferon-induced proteins. Purification and characterization of a 15,000-dalton protein from human and bovine cells induced by interferon.
1984
In vitro and in vivo secretion of human ISG15, an IFN-induced immunomodulatory cytokine.
1996
Molecular characterization of the interferon-induced 15-kDa protein. Molecular cloning and nucleotide and amino acid sequence.
1986
Interferon: purification and initial characterization from human diploid cells.
1976
Flavodoxin: A flavoprotein with ferredoxin activity from Clostridium pasteurianum
1966
Isolation and Characteristics of Flavodoxin from Nitrogen-fixing Clostridium pasteurianum
1966
A human 15-kDa IFN-induced protein induces the secretion of IFN-gamma.
1991
Fibroblast interferon induces synthesis of four proteins in human fibroblast cells.
1979
INTERFERON: EFFECT ON THE SATURATION DENSITY TO WHICH MOUSE CELLS WILL GROW IN VITRO
1973
Selective reduction of c-myc mRNA in Daudi cells by human beta interferon.
1984
Immunoregulatory properties of ISG15, an interferon-induced cytokine.
1996
Flavodoxin
1967
Interferon regulates c-myc gene expression in Daudi cells at the post-transcriptional level.
1985
Antiviral and cell growth inhibitory activities reside in the same glycoprotein of human fibroblast interferon
1976 Nature
Interferon-induced transcription of a gene encoding a 15-kDa protein depends on an upstream enhancer element.
1987
Heterogeneity of purified mouse interferons
1975
TRANSFER RNA: A COMPARISON BY GEL ELECTROPHORESIS OF THE TRNA IN HELA CYTOPLASM, HELA MITOCHONDRIAL FRACTION, AND E. coli
1969
A 15-kDa interferon-induced protein is derived by COOH-terminal processing of a 17-kDa precursor.
1988