Citation Impact
Citing Papers
Proteomic Approach to Understanding Antibiotic Action
2003
Genome sequence of an industrial microorganism Streptomyces avermitilis : Deducing the ability of producing secondary metabolites
2001 StandoutNobel
Alteration of enzyme specificity by computational loop remodeling and design
2009 StandoutNobel
Life-threatening toxicity in a dihydropyrimidine dehydrogenase-deficient patient after treatment with topical 5-fluorouracil.
1999
Gastrointestinal motor-stimulating activity of macrolide antibiotics and the structure-activity relationship.
1985 StandoutNobel
Structures of MLSBK Antibiotics Bound to Mutated Large Ribosomal Subunits Provide a Structural Explanation for Resistance
2005 StandoutNobel
Flucytosine: a review of its pharmacology, clinical indications, pharmacokinetics, toxicity and drug interactions
2000
The life and times of ivermectin — a success story
2004 StandoutNobel
Visible fluorescent detection of proteins in polyacrylamide gels without staining
2004 StandoutNobel
The emerging role of reactive oxygen species in cancer therapy
2004
cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING
2013 StandoutNature
Increase inCandida kruseiInfection among Patients with Bone Marrow Transplantation and Neutropenia Treated Prophylactically with Fluconazole
1991 Standout
Species‐specific detection of the antiviral small‐molecule compound CMA by STING
2013
Chemoradiotherapy after Surgery Compared with Surgery Alone for Adenocarcinoma of the Stomach or Gastroesophageal Junction
2001 Standout
Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial.
1997 Standout
Cytochrome P450 complement (CYPome) of the avermectin-producer Streptomyces avermitilis and comparison to that of Streptomyces coelicolor A3(2)
2003 StandoutNobel
Molecular Insights into the Biosynthesis of Guadinomine: A Type III Secretion System Inhibitor
2012 StandoutNobel
Heat Shock Protein A12B Protects Vascular Endothelial Cells Against Sepsis-Induced Acute Lung Injury in Mice
2017 Standout
Preoperative versus Postoperative Chemoradiotherapy for Rectal Cancer
2004 Standout
Methicillin-Resistant Staphylococcus aureus
1989 Standout
An orthogonal dexamethasone–trimethoprim yeast three-hybrid system
2006
The golden age: gold nanoparticles for biomedicine
2011 Standout
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis
2003 StandoutNobel
Synthesis and biological activity of new 5-O-sugar modified ketolide and 2-fluoro-ketolide antibiotics
2005
Drug resistance in human pathogenic fungi
1992
Effective Surgical Adjuvant Therapy for High-Risk Rectal Carcinoma
1991
In vitro and in vivo evaluation of antifungal agents
1989
Molecular Analysis of the Kirromycin Biosynthetic Gene Cluster Revealed β-Alanine as Precursor of the Pyridone Moiety
2008
A role for DNA mismatch repair in sensing and responding to fluoropyrimidine damage
2003
5-Fluorouracil: mechanisms of action and clinical strategies
2003 Standout
Clinical Pharmacology of 5-Fluorouracil
1989 Standout
The Biosynthetic Logic of Polyketide Diversity
2009 Standout
A small-molecule inhibitor of the bacterial type III secretion system protects against in vivo infection with Citrobacter rodentium
2010 StandoutNobel
Head and neck aspergillosis in patients undergoing bone marrow transplantation. Report of four cases and review of the literature
1986 StandoutNobel
Effect of 5-fluorouracil and thymidine on the transmembrane potential and zeta potential of HeLa cells.
1978
Antineoplastic Drugs
1978
De Novo-Designed Enzymes as Small-Molecule-Regulated Fluorescence Imaging Tags and Fluorescent Reporters
2014 StandoutNobel
Combined 5-fluorouracil and radiation therapy as a surgical adjuvant for poor prognosis gastric carcinoma.
1984
5-Fluorouracil Incorporated into DNA Is Excised by the Smug1 DNA Glycosylase to Reduce Drug Cytotoxicity
2007 StandoutNobel
Studies on fluorinated pyrimidines. IV. Effects on nucleic acid metabolism in vivo.
1958
Reaction of anthramycin with deoxyribonucleic acid
1970 StandoutNobel
Conditional Glycosylation in Eukaryotic Cells Using a Biocompatible Chemical Inducer of Dimerization
2008 StandoutNobel
Effects of anthramycin and actinomycin on RNA synthesis patterns in L1210 cells
1972 StandoutNobel
Female Reproductive Potential after Treatment for Hodgkin's Disease
1981 Standout
Prooxidant States and Tumor Promotion
1985 StandoutScience
Synthesis and Antibacterial Activity of Ketolides (6-O-Methyl-3-oxoerythromycin Derivatives): A New Class of Antibacterials Highly Potent Against Macrolide-Resistant and -Susceptible Respiratory Pathogens
1998
Antifungal Agents: Mode of Action, Mechanisms of Resistance, and Correlation of These Mechanisms with Bacterial Resistance
1999 Standout
Metabolic reduction of 4-nitroquinoline N-oxide and other radical-producing drugs to oxygen-reactive intermediates.
1977
Makrolide. Neuere Fortschritte ihrer Chemie und Biochemie
1977
Bright Side of Lignin Depolymerization: Toward New Platform Chemicals
2018 Standout
Avermectins, New Family of Potent Anthelmintic Agents: Producing Organism and Fermentation
1979 StandoutNobel
Coliphage MS2 containing 5-fluorouracil
1965 StandoutNobel
An anthelmintic compound, nafuredin, shows selective inhibition of complex I in helminth mitochondria
2000 StandoutNobel
Structural and dynamic properties of a fluorouracil-adenine base pair in DNA studied by proton NMR.
1987
Bacterial Resistance to β-Lactam Antibiotics: Compelling Opportunism, Compelling Opportunity
2005 Standout
Dihydrofluorouracil, a fluorouracil catabolite with antitumor activity in murine and human cells.
1985
Localization of angiotensin converting enzyme (kininase II). II. Immunocytochemistry and immunofluorescence
1976
Fluorouracil Therapy in Patients With Carcinoma of the Large Bowel
1978
5-Fluoro-2'-deoxyuridine incorporation in L1210 DNA.
1981
Cascade Processes of Metallo Carbenoids
1996 Standout
THE MODE OF ACTION OF 5-FLUOROURACIL AND ITS DERIVATIVES
1958 Standout
Anthramycin, a new type of DNA-inhibiting antibiotic: Reaction with DNA and effect on nucleic acid synthesis in mouse leukemia cells
1968 StandoutNobel
COMBINED 5-FLUOROURACIL AND SUPERVOLTAGE RADIATION THERAPY OF LOCALLY UNRESECTABLE GASTROINTESTINAL CANCER
1969
Studies on the mechanism of action of anthramycin methyl ether, a new antitumor antibiotic.
1969
Biologic effect of 5-fluoro-2′-deoxyuridine incorporation in L1210 deoxyribonucleic acid
1983
Combination Chemotherapy in the Treatment of Advanced Hodgkin's Disease
1970 Standout
Drug Synergism in Antineoplastic Chemotherapy
1964
Antibacterial activity of coumermycin alone and in combination with other antibiotics
1984
Adaptive strategies of the influenza virus polymerase for replication in humans
2009 StandoutNobel
Antitumor activity and some pharmacologic properties of anthramycin methyl ether.
1968
Nucleotide Formation as a Determinant of 5-Fluorouracil Response in Mouse Leukemias
1966 Science
Treatment of mice with polyinosinic-polycytidilic polyribonucleotide reduces T-cell involvement in a localized inflammatory response to vaccinia virus challenge
1985 StandoutNobel
SV 40-specific thymidine kinase.
1967 StandoutNobel
Possible Enzymic Mechanism for the Development of Resistance against Fluorouracil in Ascites Tumours
1959 Nature
ESCAPE OF A HIGHLY DEFECTIVE INFLUENZA A VIRUS MUTANT FROM ITS TEMPERATURE SENSITIVE PHENOTYPE BY EXTRAGENIC SUPPRESSION AND OTHER TYPES OF MUTATION
1980
Targeted Cancer Therapeutics
2009
Isolation and properties of the rabbit skeletal muscle protein inhibitor of adenosine 3',5'-monophosphate dependent protein kinases
1977 StandoutNobel
Avermectin Biosynthesis
1997 StandoutNobel
Practical Preparation of Trimethoprim: A Classical Antibacterial Agent
2013
Free-Energy Perturbation Calculations of DNA Destabilization by Base Substitutions: The Effect of Neutral Guanine·Thymine, Adenine·Cytosine and Adenine·Difluorotoluene Mismatches
2000 StandoutNobel
Treatment of cancer with weekly intravenous 5-fluorouracil
1968
Evaluation of interferon and interferon inducers as antiviral agents: Animal studies
1981
Genetic studies of avermectin biosynthesis in Streptomyces avermitilis
1987 StandoutNobel
5-Fluorouracil incorporation in DNA of human breast carcinoma cells.
1982
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
An efficient entry to new sugar modified ketolide antibiotics
2005
Nonlinear pharmacokinetic characteristics of 5-fluorouracil (5-FU) in colorectal cancer patients
1987
Therapy of Murine Aspergillosis with Amphotericin B in Combination with Rifampin or 5-Fluorocytosine
1977
Genetic Control of Isoniazid Metabolism in Man
1960
Fluorinated Pyrimidines and Their Nucleosides
1975
Improved Survival with Preoperative Radiotherapy in Resectable Rectal Cancer
1997 Standout
Studies on the incorporation of 5-fluorouracil into a virus nucleic acid
1959
METHYL-HYDRAZINE IN TREATMENT OF HODGKIN'S DISEASE AND VARIOUS FORMS OF HÆMATOSARCOMA AND LEUKÆMIA
1963
Fungemia in a Cancer Hospital: Changing Frequency, Earlier Onset, and Results of Therapy
1985
Studies on fluorinated pyrimidines
1959
Pharmacogenomics: Translating Functional Genomics into Rational Therapeutics
1999 StandoutScience
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy
2016 Standout
Equilibrium between a wobble and ionized base pair formed between fluorouracil and guanine in DNA as studied by proton and fluorine NMR.
1988
Studies on fluorinated pyrimidines. XI. In vitro studies on tumor resistance.
1960
A Methylhydrazine Derivative in Hodgkin's Disease and Other Malignant Neoplasms
1965
Studies on resistance against 5-fluorouracil. III. Selective value of resistant, uridine kinase-deficient tumor cells.
1962
Carbanionic Friedel−Crafts Equivalents. Regioselective Directed Ortho and Remote Metalation−C−N Cross Coupling Routes to Acridones and Dibenzo[b,f]azepinones
2008
Studies on Fluorinated Pyrimidines
1960
Estimation of molecular weight by polyacrylamide gel electrophoresis using heat stable fluorophors
1976
An In Vivo Covalent TMP-Tag Based on Proximity-Induced Reactivity
2009
Works of E. Grunberg being referenced
Glycoside cleavage reactions on erythromycin A. Preparation of erythronolide A
1974
Chemotherapeutic Properties of Anthramycin
1966
Antiviral Activity of 10-Carboxymethyl-9-Acridanone
1976
Improved synthesis of diaveridine, trimethoprim, and closely related 2,4-diaminopyrimidines
1971
Studies on fluorinated pyrimidines. II. Effects on transplanted tumors.
1958
CHEMOTHERAPEUTIC ACTIVITY OF 5-FLUOROCYTOSINE.
1963
Chemotherapeutic Activity of 5-Fluorocytosine and Amphotericin B Against Candida albicans in Mice
1973
Chemotherapeutic properties of coumermycin A1.
1965
Studies on the <i>in vitro</i> and <i>in vivo</i> Chemotherapeutic Properties of the Antibiotic Myxin
1967
Synthesis and chemotherapeutic activity of two metabolites of trimethoprim
1971
A NEW ANTIBIOTIC X-5108 OF STREPTOMYCES ORIGIN
1973
The Effect of Trimethoprim on the Activity of Sulfonamides and Antibiotics in Experimental Infections
1973
Fluorescent labeling of proteins. A new methodology
1973
Fluorinated Pyrimidines VI. Effects of 5-Fluorouridine and 5-Fluoro-2'-Deoxyuridine on Transplanted Tumors.
1958
Tumour inhibitory effects of a new class of cytotoxic agents: Methylhydrazine derivatives
1963
Chemotherapeutic Properties of Heterocyclic Compounds: Monocyclic Compounds with Five-Membered Rings
1973
On the Lasting Protective Effect of Hydrazine Derivatives of Isonicotinic Acid in the Experimental Tuberculosis Infection of Mice
1952