Citation Impact
Citing Papers
Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma
2003 StandoutNobel
Recognition of a Ubiquitous Self Antigen by Prostate Cancer-Infiltrating CD8 + T Lymphocytes
2008 StandoutScienceNobel
HIV controllers exhibit potent CD8 T cell capacity to suppress HIV infection ex vivo and peculiar cytotoxic T lymphocyte activation phenotype
2007 StandoutNobel
Effective expansion of alloantigen-specific Foxp3 + CD25 + CD4 + regulatory T cells by dendritic cells during the mixed leukocyte reaction
2006 StandoutNobel
MHC-Restricted Cytotoxic T Cells: Studies on the Biological Role of Polymorphic Major Transplantation Antigens Determining T-Cell Restriction-Specificity, Function, and Responsiveness
1979 StandoutNobel
Highly polymorphic products of both HLA-DR and HLA-DQ genes contribute to the polymorphism of the HLA-DR w13 haplotype
1986
Self-Amplifying mRNA Vaccines
2014
Peptide-binding specificity of the molecular chaperone BiP
1991 StandoutNatureNobel
Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma
1998 Standout
Antiviral pressure exerted by HIV-l-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus
1997
mRNA Cancer Vaccines—Messages that Prevail
2017
Combination of HIV‐1–Specific CD4 Th1 Cell Responses and IgG2 Antibodies Is the Best Predictor for Persistence of Long‐Term Nonprogression
2005
mRNA vaccines — a new era in vaccinology
2018 StandoutNobel
mRNA-based cancer vaccine: prevention of B16 melanoma progression and metastasis by systemic injection of MART1 mRNA histidylated lipopolyplexes
2007
Lipid nanoparticles for mRNA delivery
2021 Standout
The European Regulatory Environment of RNA-Based Vaccines
2016
mRNA-based therapeutics — developing a new class of drugs
2014 StandoutNobel
RNA Melanoma Vaccine: Induction of Antitumor Immunity by Human Glycoprotein 100 mRNA Immunization
1999
Characterization of the ribonuclease activity on the skin surface
2006
Polarization of immunity induced by direct injection of naked sequence-stabilized mRNA vaccines
2004
RNA: The new revolution in nucleic acid vaccines
2013
Sequence-engineered mRNA Without Chemical Nucleoside Modifications Enables an Effective Protein Therapy in Large Animals
2015
mRNA
2013
Impact of Antiretroviral Therapy and Changes in Virus Load on Human Immunodeficiency Virus (HIV)–Specific T Cell Responses in Primary HIV Infection
2003
Peptides Naturally Presented by MHC Class I Molecules
1993
Type I IFN Counteracts the Induction of Antigen-Specific Immune Responses by Lipid-Based Delivery of mRNA Vaccines
2012
Refined structure of the human histocompatibility antigen HLA-A2 at 2.6 Å resolution
1991
Murine cytotoxic T-cell response to alphavirus is associated mainly withH- 2D k
1978
A novel, disruptive vaccination technology
2013
Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules
1991 StandoutNature
The ReNAissanCe of mRNA-based cancer therapy
2014
Epitope affinity for MHC class I determines helper requirement for CTL priming
2000 StandoutNobel
Self-replicating Semliki Forest virus RNA as recombinant vaccine
1994
Type 1/Type 2 Immunity in Infectious Diseases
2001
Comprehensive Analyses of a Unique HIV-1-Infected Nonprogressor Reveal a Complex Association of Immunobiological Mechanisms in the Context of Replication-Incompetent Infection
2002
Immunosuppressive properties of synthetic peptides derived from CD4 and HLA-DR antigens
1988 StandoutNobel
Restoring function in exhausted CD8 T cells during chronic viral infection
2005 StandoutNatureNobel
Virus-induced autoantibody response to a transgenic viral antigen
1990 StandoutNatureNobel
Toll‐like receptor‐dependent activation of several human blood cell types by protamine‐condensed mRNA
2005
Vaccination with Messenger RNA (mRNA)
2007
Developing mRNA-vaccine technologies
2012
Isolation of an endogenously processed immunodominant viral peptide from the class I H–2Kb molecule
1990 Nature
Peptide binding to the most frequent HLA-A class I alleles measured by quantitative molecular binding assays
1994
Lipid-based mRNA vaccine delivery systems
2014
Extrathymic positive selection of αβ T-cell precursors in nude mice
1992 StandoutNatureNobel
RNA-based vaccines
2012
mRNA Cancer Vaccines
2016
Mouse cytolytic T lymphocytes induced by xenogeneic rat stimulator cells exhibit specificity for H-2 complex alloantigens.
1977 StandoutNobel
H-2-restricted cytotoxic effectors generated in vitro by the addition of trinitrophenyl-conjugated soluble proteins
1978
Generation of cytolytic T lymphocytes after reovirus infection: role of S1 gene.
1979 StandoutNobel
Enhanced immunological surveillance in mice heterozygous at the H-2 gene complex
1975 StandoutNatureNobel
Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates
2011 StandoutNobel
2015
The mouse T cell receptor: Structural heterogeneity of molecules of normal T cells defined by Xenoantiserum
1983 StandoutNobel
Cytotoxic T lymphocytes induced in mice by inactivated influenza virus vaccine
1977 Nature
The Murine Sarcoma Virus-Induced Tumor: Exception or General Model in Tumor Immunology?
1977
Secondary cytotoxic cell response to lymphocytic choriomeningitis virus. I. Kinetics of induction in vitro and yields of effector cells.
1976
Induction of cellular immunity by immunization with novel hybrid peptides complexed to heat shock protein 70
2000 StandoutNobel
DEC-205 receptor on dendritic cells mediates presentation of HIV gag protein to CD8 + T cells in a spectrum of human MHC I haplotypes
2007 StandoutNobel
Structural Proteins of Mammalian Oncogenic RNA Viruses: Multiple Antigenic Determinants of the Major Internal Protein and Envelope Glycoprotein
1974
Expression in transgenic mice of class I histocompatibility antigens controlled by the metallothionein promoter.
1989 StandoutNobel
The isolation and nucleotide sequence of a cDNA encoding the T cell surface protein T4: a new member of the immunoglobulin gene family
1985 StandoutNobel
Vaccination with mRNAs encoding tumor-associated antigens and granulocyte-macrophage colony-stimulating factor efficiently primes CTL responses, but is insufficient to overcome tolerance to a model tumor/self antigen
2005
H-2 Mutations: Their Genetics and Effect on Immune Functions
1978
Regulation of immune response to tumor antigen: interference with syngeneic tumor immunity by anti-IA alloantisera.
1979 StandoutNobel
CD40 Ligand-Mediated Interactions Are Involved in the Generation of Memory CD8+Cytotoxic T Lymphocytes (CTL) but Are Not Required for the Maintenance of CTL Memory following Virus Infection
1998
Primary and secondary in vitro generation of cytolytic T lymphocytes in the murine sarcoma virus system
1975
Secondary specific immune response in vitro to MSV tumor cells
1975
Induction of AIDS Virus-Specific CTL Activity in Fresh, Unstimulated Peripheral Blood Lymphocytes from Rhesus Macaques Vaccinated with a DNA Prime/Modified Vaccinia Virus Ankara Boost Regimen
2000
Thymus Derived Killer Cells: Specificity of Function, and Antigen Recognition
1976
Interspecies exchange of β 2-microglobulin and associated MHC and differentiation antigens
1981
mRNA Vaccine Delivery Using Lipid Nanoparticles
2016
Identification of overlapping HLA class I-restricted cytotoxic T cell epitopes in a conserved region of the human immunodeficiency virus type 1 envelope glycoprotein: definition of minimum epitopes and analysis of the effects of sequence variation.
1992
Nonviral delivery of self-amplifying RNA vaccines
2012
Lysis of herpesvirus-infected cells by immune spleen cells
1975
A Single Amino Acid Interchange Yields Reciprocal CTL Specificities for HIV-1 gp160
1989 Science
Persistent hepatitis C virus infection in a chimpanzee is associated with emergence of a cytotoxic T lymphocyte escape variant.
1995 StandoutNobel
Mhc RESTRICTION AND Ir GENES
1982
Antiviral antibodies inhibit the lysis of tumour cells by anti-H–2 sera
1976 NatureNobel
In vivo persistence of a HIV‐1‐encoded HLA‐B27‐restricted cytotoxic T lymphocyte epitope despite specific in vitro reactivity
1991
A development that may evolve into a revolution in medicine: mRNA as the basis for novel, nucleotide-based vaccines and drugs
2013
Reciprocal stimulation of negatively selected high-responder and low-responder T cells in virus-infected recipients.
1979 StandoutNobel
Alphavirus-based expression vectors: strategies and applications.
1996 StandoutNobel
Thymus dictates major histocompatibility complex (MHC) specificity and immune response gene phenotype of class II MHC-restricted T cells but not of class I MHC-restricted T cells.
1984
Lysis of leukemia cells by spleen cells of normal mice.
1975
Reduction of syngeneic tumor growth by an anti-I-J-alloantiserum.
1977 StandoutNobel
A third rearranged and expressed gene in a clone of cytotoxic T lymphocytes
1984 StandoutNatureNobel
A multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes
2022 StandoutScienceNobel
Cell‐mediated cytotoxicity against ectromelia virus‐infected target cells. III. Role of the H‐2 gene complex
1975
Serum β2-microglobulin binds to a T-cell differentiation antigen and increases its expression
1984 StandoutNatureNobel
Therapeutic Vaccines for Chronic Infections
2004 Science
Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients
2003 StandoutNobel
Cytotoxic T-cell responses in mice infected with influenza and vaccinia viruses vary in magnitude with H-2 genotype.
1978 StandoutNobel
Cell-Mediated Cytotoxicity, Allograft Rejection, and Tumor Immunity
1974 Standout
The HLA-dependent expression of testis-organizing H-Y antigen by human male cells
1978 StandoutNobel
RNA-Based Vaccines in Cancer Immunotherapy
2015
Maintenance of viral suppression in HIV-1–infected HLA-B*57+ elite suppressors despite CTL escape mutations
2006
Evidence of widespread binding of HLA class I molecules to peptides.
1990
Alpha/beta T-cell antigen receptor gene and protein expression occurs at early stages of thymocyte differentiation.
1988 StandoutNobel
Joint recognition by cytotoxic T cells of inactivated Sendai virus and products of the major histocompatibility complex.
1977 Nobel
H-2-linked control of cytotoxic T-cell responsiveness to alphavirus infection. Presence of H-2Dk during differentiation and stimulation converts stem cells of low responder genotype to T cells of responder phenotype.
1979
Specificity of the T Cells That Mediate and Suppress Adoptive Immunotherapy of Established Tumors
1984
H‐2‐linked murine cytotoxic T cell responses specific for sendai virus‐infected cells
1978
IMMUNOGENETIC STUDIES ON METH‐A‐VACCINIA TUMOUR CELLS IN VIVO AND IN VITRO*
1977
Lipid Nanoparticle Assisted mRNA Delivery for Potent Cancer Immunotherapy
2016
Broad, Intense Anti-Human Immunodeficiency Virus (HIV) Ex Vivo CD8+Responses in HIV Type 1-Infected Patients: Comparison with Anti-Epstein-Barr Virus Responses and Changes during Antiretroviral Therapy
1999
Influence of the Major Histocompatibility Complex on T-Cell Activation
1979
In vitro evidence of cell-mediated immunity after exposure of mice to both live and inactivated rabies virus.
1977 StandoutNobel
H—2-restricted cytolytic T cells specific for HLA can recognize a synthetic HLA peptide
1986 Nature
Immunogenetic analysis ofH-2 mutations
1977
Synthetic peptides as antigens and competitors in recognition by H-2-restricted cytolytic T cells specific for HLA.
1988
Major Histocompatibility Complex Restricted Cell-Mediated Immunity
1978
Hepatitis C virus (HCV)-specific cytotoxic T lymphocytes recognize epitopes in the core and envelope proteins of HCV
1993 StandoutNobel
Cytotoxicity against tumour-associated antigens not H–2 restricted
1977 Nature
Experiments and Speculation on Antiviral Specificity of T and B Cells
1981
Association of Mouse Major Histocompatibility and Rauscher Murine Leukaemia Virus Envelope Glycoprotein Antigens on Leukaemia Cells and their Recognition by Syngeneic Virus‐Immune‐Cytotoxic T‐Lymphocytes
1978
Different rules govern help for cytotoxic T cells and B cells
1978 StandoutNatureNobel
A one-receptor view of T-cell behaviour
1981 Nature
Throughput-scalable manufacturing of SARS-CoV-2 mRNA lipid nanoparticle vaccines
2023 StandoutNobel
H–2 restriction and non-restriction of T-cell-mediated cytotoxicity against mouse mammary tumour targets
1978 Nature
Antigenic specificities of the cell‐mediated anti‐tumor reactions in the MSV system studied by the secondary chromium release test
1975
Cross-reactive lysis of trinitrophenyl (TNP)-derivatized H-2 incompatible target cells by cytolytic T lymphocytes generated against syngeneic TNP spleen cells.
1976
Antigenic specificity of the cytolytic T lymphocyte (CTL) response to murine sarcoma virus‐induced tumors. I. Preferential reactivity of in vitro generated secondary CTL with syngeneic tumor cells
1976
THE UBIQUITIN SYSTEM
1998 StandoutNobel
T‐Cell‐Mediated Immunopathology in Viral Infections
1974 StandoutNobel
Dendritic cells pulsed with RNA are potent antigen-presenting cells in vitro and in vivo.
1996
Messenger RNA-based vaccines
2004
Multiple H-2-linked immune response gene control of H-2D- associated T-cell-mediated lympholysis to trinitrophenyl-modified autologous cells: Ir-like genes mapping to the left of I-A and within the I region
1976
Radioimmunoassay for intact Gross mouse leukemia virus.
1976 StandoutNobel
Cell‐mediated cytotoxicity against ectromelia virus‐infected target cells. II. Identification of effector cells and analysis of mechanisms
1974
A BIOLOGICAL ROLE FOR THE MAJOR HISTOCOMPATIBILITY ANTIGENS
1975 StandoutNobel
H–2 Antigens on a murine lymphoma are associated with additional proteins
1978 StandoutNatureNobel
Biological Function of HLA
1978
Resistance to transplantation of spontaneous AKR lymphoma cells by substrains of AKR mice
1978
The microbial mimic poly IC induces durable and protective CD4+T cell immunity together with a dendritic cell targeted vaccine
2008 StandoutNobel
Positive selection of HIV-1 cytotoxic T lymphocyte escape variants during primary infection
1997
Non-adaptive rejection of small tumour inocula as a model of immune surveillance
1976 Nature
Biological significance of alloreactivity: T cells stimulated by Sendai virus-coated syngeneic cells specifically lyse allogeneic target cells.
1978 StandoutNobel
H–2 gene expression is required for T cell-mediated lysis of virus-infected target cells
1977 StandoutNatureNobel
Mode of action of Ir genes and the nature of T cell receptors for antigen
1976
The Specificity of Effector T Cells Activated by Tumours Induced by Murine Oncornaviruses
1976
Heterogeneity of the cytotoxic response of thymus-derived lymphocytes after immunization with influenza viruses.
1977 StandoutNobel
Works of E Gomard being referenced
Delayed Virus-Specific CD8 + Cytotoxic T Lymphocyte Activity in an HIV-Infected Individual with High CD4 + Cell Counts: Correlations with Various Parameters of Disease Progression*
1996
Evolution of Cytotoxic T Lymphocyte Responses to Human Immunodeficiency Virus Type 1 in Patients with Symptomatic Primary Infection Receiving Antiretroviral Triple Therapy
1998
Correlation between breadth of memory HIV-specific cytotoxic T cells, viral load and disease progression in HIV infection
2002
Physical association between MHC class I molecules and immunogenic peptides
1989 Nature
Influence of strong CD4 epitope on long-term virus-specific cytotoxic T cell responses induced in vivo with peptides
1996
An antigenic peptide of the HIV‐1 NEF protein recognized by cytotoxic T lymphocytes of seropositive individuals in association with different HLA‐B
1989
Induction of virus‐specific cytotoxic T lymphocytes in vivo by liposome‐entrapped mRNA
1993
Comparison of subcutaneous and intravenous interleukin-2 in asymptomatic HIV-1 infection: a randomised controlled trial
1999
Qualitative and quantitative analysis of human cytotoxic T-lymphocyte responses to HIV-1 proteins
1992
Predominant involvement of CD8+CD28- lymphocytes in human immunodeficiency virus-specific cytotoxic activity
1996
Two epitopes and one agretope map to a single HLA-A2 peptide recognized by H-2-restricted T cells.
1989
Cell‐mediated immune reaction against tumors induced by oncornaviruses. III. Studies by mixed lymphocyte—tumor reaction
1973
Murine Leukemia and Sarcoma Viruses: Further Studies on the Antigens ofthe Viral Envelope
1973
RELATIONSHIPS BETWEEN H‐2 AND VIRAL ANTIGENS IN MURINE ONCORNAVIRUS‐INDUCED TUMOURS*
1977
H–2 region product as determinant in immune cytolysis of syngeneic tumour cells by anti-MSV T lymphocytes
1976 Nature
HLA-binding regions of HIV-1 proteins. II. A systematic study of viral proteins.
1991
Analysis of physical interactions between peptides and HLA molecules and application to the detection of human immunodeficiency virus 1 antigenic peptides.
1990
Comparative in Vitro Studies on Effector Cell Diversity in the Cellular Immune Response to Murine Sarcoma Virus (MSV)-Induced Tumors in Mice
1974
Cytostasis of lymphoma cells in suspension: Probable non‐thymic origin of the cytostatic lymphoid cells in mice bearing MSV‐induced tumors
1974
Studies on the nature of the cell surface antigen reacting with cytolytic T lymphocytes in murine oncornavirusinduced tumors
1978
Spontaneous antilymphoma reaction of preleukaemic AKR mice is a non-T-cell killing
1974 Nature
Significance of the proline assay in the study of anti-MSV cell-mediated immune reactions
1979
HLA-binding regions of HIV-1 proteins. I. Detection of seven HLA binding regions in the HIV-1 Nef protein
1991
Cell‐mediated immune reaction against tumors induced by oncornaviruses. II. Nature of the effector cells in tumor‐cell cytolysis
1973
Cell‐mediated anti‐tumor response in the RL♂ 1 system I. T nature, H‐2 Dd involvement and antigenic specificity of the effector cells
1978
Fine specificity analysis of human influenza-specific cloned cell lines
1985
Despite lack of monospecific anti-DRw13 sera, a corresponding class II determinant can be defined by a DRw13 restricted anti-influenza virus T cell clone
1986
Six epitopes reacting with human cytotoxic CD8+ T cells in the central region of the HIV-1 NEF protein.
1991
Cell‐mediated reaction against tumors induced by oncornaviruses. I. Kinetics and specificity of the immune response in Murine sarcoma virus (MSV)‐induced tumors and transplanted lymphomas
1972
Impaired cytotoxic T lymphocyte recognition due to genetic variations in the main immunogenic region of the human immunodeficiency virus 1 NEF protein.
1994
Exclusive involvement of H-2D(b) or H-2K(d) product in the interaction between T-killer lymphocytes and syngeneic H-2(b) or H-2(d) viral lymphomas
1977
Limiting-dilution analysis of the HLA restriction of anti-Epstein-Barr virus-specific cytolytic T lymphocytes.
1991
Further Evidence for the Involvement of Thymus-Processed Lymphocytes in Syngeneic Tumor Cell Cytolysis
1973
Murine cells expressing an HLA molecule are specifically lysed by HLA-restricted antiviral human T cells
1986 Nature
Delineation of determinants on HLA-B7 and HLA-B27 that are necessary for cytolytic T cell recognition by using inter- and intra-domain recombinants.
1989
Immune response genes control T killer cell response against Moloney tumor antigen cytolysis regulating reactions against the best available H-2 + viral antigen association.
1980