Citation Impact
Citing Papers
Structural, conformational, and stereochemical requirements of central excitatory amino acid receptors
1990
Ionotropic and metabotropic glutamate receptor structure and pharmacology
2005
The ontogeny of excitatory amino acid receptors in the rat forebrain—II. Kainic acid receptors
1990
Kainate receptor gene expression in the developing rat brain
1994
The KA-2 subunit of excitatory amino acid receptors shows widespread expression in brain and forms ion channels with distantly related subunits
1992 Nobel
Evidence for an Astrocytic Glutamate Transporter Deficit in Hepatic Encephalopathy
1999
Molecular cloning and characterization of the rat NMDA receptor
1991 StandoutNature
Combinatorial peptide libraries in drug design: lessons from venomous cone snails
1995
Glutamate Release from Guinea‐Pig Synaptosomes: Stimulation by Reuptake‐Induced Depolarization
1989
Domain Interaction Between NMDA Receptor Subunits and the Postsynaptic Density Protein PSD-95
1995 StandoutScience
β-N-Methylamino-l-alanine in the presence of bicarbonate is an agonist at non- N-methyl-d-aspartate-type receptors
1993
Glutamate uptake
2001 Standout
Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2
2004 StandoutNature
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain
2016 StandoutNatureNobel
Marine natural products
1990 Standout
Marine natural products
2009
Glutamate receptors in the mammalian central nervous system
1998
Localization of agonist and competitive antagonist binding sites on nicotinic acetylcholine receptors
2000
Development of antibody-based assays for omega-conotoxin MVIIA
2006
The high affinity uptake system for excitatory amino acids in the brain
1994
A Bivalent Tarantula Toxin Activates the Capsaicin Receptor, TRPV1, by Targeting the Outer Pore Domain
2010 StandoutNobel
Cloning of a putative high-affinity kainate receptor expressed predominantly in hippocampal CA3 cells
1991 Nature
An SCN9A channelopathy causes congenital inability to experience pain
2006 StandoutNature
β-Lactam antibiotics offer neuroprotection by increasing glutamate transporter expression
2005 StandoutNature
Subtypes of Sodium‐Dependent High‐Affinity L‐[3H]Glutamate Transport Activity: Pharmacologic Specificity and Regulation by Sodium and Potassium
1993
A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain
2011 StandoutNatureNobel
A rational nomenclature for naming peptide toxins from spiders and other venomous animals
2008
The Excitatory Amino Acid Receptors: Their Classes, Pharmacology, and Distinct Properties in the Function of the Central Nervous System
1989 Standout
Heterogeneity and Functional Properties of Subtypes of Sodium-Dependent Glutamate Transporters in the Mammalian Central Nervous System
1996
A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain
2019 StandoutNobel
TRPV1 structures in distinct conformations reveal activation mechanisms
2013 StandoutNatureNobel
Autoradiographic characterization of putative excitatory amino acid transport sites
1990
NMDA receptor subunits: diversity, development and disease
2001
Effects of hyperammonaemia on brain function
1998
cAMP contributes to mossy fiber LTP by initiating both a covalently mediated early phase and macromolecular synthesis-dependent late phase
1994 StandoutNobel
The chemical synthesis of proteins
1993
A Novel Post-translational Modification Involving Bromination of Tryptophan
1997
Tacrine: A pharmacological review
1991
Bioactive cystine knot proteins
2011
Effects of ammonia on glutamate transporter (GLAST) protein and mRNA in cultured rat cortical astrocytes
2000
The ontogeny of excitatory amino acid receptors in rat forebrain—I.N-methyl-d-aspartate and quisqualate receptors
1990
Spider toxins activate the capsaicin receptor to produce inflammatory pain
2006 StandoutNatureNobel
Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors
2001 StandoutNature
The cystine knot motif in toxins and implications for drug design
2001
Postnatal Age and Protein Tyrosine Phosphorylation at Synapses in the Developing Rat Brain
1991
Folding of Conotoxins: Formation of the Native Disulfide Bridges During Chemical Synthesis and Biosynthesis of Conus Peptides
2007
Characterization of Glutamate Uptake into Synaptic Vesicles
1985
On the excitotoxic properties of quinolinic acid, 2,3-piperidine dicarboxylic acids and structurally related compounds
1983
The long and the short of long–term memory—a molecular framework
1986 StandoutNatureNobel
Saving the "library of life".
1992
Drug Discovery and Natural Products: End of an Era or an Endless Frontier?
2009 StandoutScience
E.E. Just Lecture, 1996
1997
Molecular genetics of ecological diversification: Duplication and rapid evolution of toxin genes of the venomous gastropod Conus
1999
Postsynaptic N -methyl- d -aspartate receptor function requires α-neurexins
2004 StandoutNobel
Strategy for rapid immobilization of prey by a fish-hunting marine snail
1996 Nature
Glutamate Induces Calcium Waves in Cultured Astrocytes: Long-Range Glial Signaling
1990 StandoutScience
The Biochemistry of Memory: A New and Specific Hypothesis
1984 Science
Primary structure and functional expression of the human receptor for Escherichia coli heat-stable enterotoxin.
1991
Glycine potentiates the NMDA response in cultured mouse brain neurons
1987 StandoutNature
Effects of In Vivo Administration of Kainic Acid on the Extracellular Amino Acid Pool in the Rabbit Hippocampus
1983
The Medial Temporal Lobe Memory System
1991 StandoutScience
Receptors for the excitatory amino acids in the mammalian central nervous system
1983
Impaired Long-Term Potentiation, Spatial Learning, and Hippocampal Development in fyn Mutant Mice
1992 StandoutScienceNobel
Inactivation of a Serotonin-Gated Ion Channel by a Polypeptide Toxin from Marine Snails
1998 StandoutScienceNobel
A chloride- and calcium-dependent glutamate-binding protein from rat brain. Identification as a ubiquitous constituent of the inner mitochondrial membrane.
1990
Long-Term Potentiation--A Decade of Progress?
1999 StandoutScience
Blockade of N -Methyl-D-Aspartate Receptors May Protect Against Ischemic Damage in the Brain
1984 StandoutScience
A vesicle carrier that mediates peroxisome protein traffic from the endoplasmic reticulum
2010 StandoutNobel
The Vitamin K-dependent Carboxylase
2002
A Family of AMPA-Selective Glutamate Receptors
1990 StandoutScienceNobel
Scorpion toxins as natural scaffolds for protein engineering.
1995
Characteristics of chloride-dependent incorporation of glutamate into brain membranes argue against a receptor binding site
1987
Na+‐Dependent “Binding” of D‐Aspartate in Brain Membranes Is Largely Due to Uptake into Membrane‐Bounded Saccules
1986
l-Glutamate, excitatory amino acid receptors and brain function
1985
Mice carrying a human GLUD2 gene recapitulate aspects of human transcriptome and metabolome development
2016 StandoutNobel
Structural Determinants of Ion Flow Through Recombinant Glutamate Receptor Channels
1991 StandoutScienceNobel
Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5
1986 StandoutNature
Multiple Synaptic Receptors for Neuroactive Amino Acid Transmitters—New Vistas
1985
Conotoxins.
1991
DNA Banks for Endangered Animal Species
2000 StandoutScienceNobel
Alternative splicing generates functionally distinct N-methyl-D-aspartate receptors.
1992 StandoutNobel
The Ca2+/Cl− dependent L‐[3H]glutamate binding: a new receptor or a particular transport process?
1984
Evolutionary origin of inhibitor cystine knot peptides
2003
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
The distribution of [3H]kainic acid binding sites in rat CNS as determined by autoradiography
1982
II. Excitotoxic models for neurodegenerative disorders
1984
Acidic amino acid binding sites in mammalian neuronal membranes: their characteristics and relationship to synaptic receptors
1984
2-Amino-4-phosphonobutyrate selectively blocks mossy fiber-CA3 responses in guinea pig but not rat hippocampus
1984
Cloning of a putative glutamate receptor: A low affinity kainate-binding subunit
1992
Distribution of [3H]AMPA binding sites in rat brain as determined by quantitative autoradiography
1984
Presynaptic glutamate receptors depress excitatory monosynaptic transmission between mouse hippocampal neurones.
1990
The upregulation of acetylcholine release at endplates of alpha‐bungarotoxin‐treated rats: its dependency on calcium.
1994
The Role of Sodium Channels in Chronic Inflammatory and Neuropathic Pain
2006
Plasticity of Hippocampal Circuitry in Alzheimer's Disease
1985 Science
Mechanisms for the pleiotropic effects of the agouti gene.
1995
ConusVenoms: A Rich Source of Novel Ion Channel-Targeted Peptides
2004
Antagonism of Central Melanocortin Receptors in Vitro and in Vivo by Agouti-Related Protein
1997 StandoutScience
Mechanical Bonds and Topological Effects in Radical Dimer Stabilization
2014 StandoutNobel
Flip and Flop: A Cell-Specific Functional Switch in Glutamate-Operated Channels of the CNS
1990 StandoutScienceNobel
Involvement of excitatory amino acids in neurotransmission of inspiratory drive to spinal respiratory motoneurons
1989
Emerging Targets in Photopharmacology
2016 StandoutNobel
Pre-Bötzinger Complex: a Brainstem Region that May Generate Respiratory Rhythm in Mammals
1991 StandoutScience
Enzymatic aminoacylation of tRNA with unnatural amino acids
2006 StandoutNobel
Reducing Endogenous Tau Ameliorates Amyloid ß-Induced Deficits in an Alzheimer's Disease Mouse Model
2007 StandoutScience
Oxidative Stress, Glutamate, and Neurodegenerative Disorders
1993 StandoutScience
Glutamate: A Neurotransmitter in Mammalian Brain
1984 Standout
Anticonvulsant Action of Excitatory Amino Acid Antagonists
1982 Science
γ-Glutamyl carboxylation: An extracellular posttranslational modification that antedates the divergence of molluscs, arthropods, and chordates
2002
The physiology of excitatory amino acids in the vertebrate central nervous system
1987 Standout
Characterization of Na+-dependent binding sites of [3H]glutamate in synaptic membranes from rat brain
1986
Synaptic Assembly of the Brain in the Absence of Neurotransmitter Secretion
2000 StandoutScienceNobel
A receptor guanylyl cyclase expressed specifically in olfactory sensory neurons.
1995 StandoutNobel
Neurotoxins Affecting Neuroexocytosis
2000 Standout
Synthesis of Proteins by Native Chemical Ligation
1994 StandoutScience
Guam Amyotrophic Lateral Sclerosis-Parkinsonism-Dementia Linked to a Plant Excitant Neurotoxin
1987 StandoutScience
Elicitation of structure-specific antibodies by epitope scaffolds
2010 StandoutNobel
Molecular Diversity of Glutamate Receptors and Implications for Brain Function
1992 StandoutScience
Inhibition by K+ of Na+‐Dependent D‐Aspartate Uptake into Brain Membrane Saccules
1986
Heteromeric NMDA Receptors: Molecular and Functional Distinction of Subtypes
1992 StandoutScienceNobel
Works of E. Edward Mena being referenced
The binding of a monoclonal antibody reactive with pp60v-src to the rat CNS both in vitro and in vivo: evidence that the epitope is present intracellularly as well as being associated with a number of antigenically related polypeptides located externally in the plasma membrane only in the synapic region
1988
Conantokin-G: A novel peptide antagonist to the acid (NMDA) receptor
1990
l-ß-Methylaminoalanine inhibits [3H]glutamate binding in the presence of bicarbonate ions
1989
Correlation of brain levels of 9-amino-1,2,3,4-tetrahydroacridine (THA) with neurochemical and behavioral changes
1989
Chloride and calcium ions separte L-glutamate receptor populations in synaptic membranes
1983
Pathologic concentrations of ammonium ions block l-glutamate uptake
1985
Cations differentially affect subpopulations ofl-glutamate receptors in rat synaptic plasma membranes
1985
Conantokin-T. A gamma-carboxyglutamate containing peptide with N-methyl-d-aspartate antagonist activity.
1990
Regional distribution and ionic requirement of Cl−/Ca2+-activated and Cl−/Ca2+-independent glutamate receptors in rat brain
1983
Diversity of Conus Neuropeptides
1990 Science
Glutamate and aspartate binding sites are enriched in synaptic junctions isolated from rat brain
1981
ChemInform Abstract: (1S,2S)‐1‐(4‐Hydroxyphenyl)‐2‐(4‐hydroxy‐4‐phenylpiperidino)‐1‐ propanol: A Potent New Neuroprotectant Which Blocks N‐Methyl‐D‐ aspartate Responses.
1995
Chloride and calcium ions reveal a pharmacologically distinct population of L-glutamate binding sites in synaptic membranes: correspondence between biochemical and electrophysiological data
1982
Chloride ions enhance L-glutamate binding to rat brain synaptic membranes
1982
Freezing eliminates a specific population of l-glutamate receptors in synaptic membranes
1983
L-glutamate and l-aspartate bind to separate sites in rat brain synaptic membranes
1981
Synaptic localization of kainic acid binding sites
1981 Nature
Identification of Synapse Specific Components: Synaptic Glycoproteins, Proteins, and Transmitter Binding Sites
1981