Citation Impact
Citing Papers
Ligand-tethered lipid nanoparticles for targeted RNA delivery to treat liver fibrosis
2023 StandoutNobel
Redox mechanisms in hepatic chronic wound healing and fibrogenesis
2008
The Transcriptional and DNA Binding Activity of Peroxisome Proliferator-activated Receptor α Is Inhibited by Ethanol Metabolism
2001
Molecular mediators of hepatic steatosis and liver injury
2004 Standout
Thiazolidinediones
2004 Standout
CYP2E1-mediated oxidative stress induces collagen type I expression in rat hepatic stellate cells
1999
Idiopathic pulmonary fibrosis
2017 Standout
Improved nonalcoholic steatohepatitis after 48 weeks of treatment with the PPAR-γ ligand rosiglitazone
2003
Lipid peroxidation in hepatic steatosis in humans is associated with hepatic fibrosis and occurs predominately in acinar zone 3
2001
Disruption of transforming growth factor-β signaling by curcumin induces gene expression of peroxisome proliferator-activated receptor-γ in rat hepatic stellate cells
2006
Role of Obesity and Lipotoxicity in the Development of Nonalcoholic Steatohepatitis: Pathophysiology and Clinical Implications
2012
Expression of HSP47, a collagen-specific chaperone, in normal and diseased human liver
2005
Selective Na+/H+ exchange inhibition by cariporide reduces liver fibrosis in the rat
2003
Liver fibrosis
2005 Standout
Pregnane X Receptor Activators Inhibit Human Hepatic Stellate Cell Transdifferentiation In Vitro
2006
Association of differentially expressed genes with activation of mouse hepatic stellate cells by high-density cDNA mircoarray
2004
The role and regulation of hepatic stellate cell apoptosis in reversal of liver fibrosis
2005
Chronic Alcohol Intake Interferes with Retinoid Metabolism and Signaling
2009
Neuroprotective Properties of Nitric Oxide
1999
The Global Impact of Hepatic Fibrosis and End-Stage Liver Disease
2008
Oxidative stress-related molecules and liver fibrosis
2001
Mechanisms of liver fibrosis
2005
Molecular mechanisms of epithelial–mesenchymal transition
2014 Standout
Activation of rat hepatic stellate cells leads to loss of glutathion S -transferases and their enzymatic activity against products of oxidative stress
1999
Liver fibrosis – from bench to bedside
2003 Standout
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
2013 StandoutNature
Peroxisome proliferator-activated receptor-β signaling contributes to enhanced proliferation of hepatic stellate cells
2003
PI-3 K/AKT and ERK signaling pathways mediate leptin-induced inhibition of PPARγ gene expression in primary rat hepatic stellate cells
2009
Design and validation of a histological scoring system for nonalcoholic fatty liver disease†
2005 Standout
The metabolic syndrome
2010 Standout
TLR4 enhances TGF-β signaling and hepatic fibrosis
2007 Standout
Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB
2005 Standout
NADPH oxidase signal transduces angiotensin II in hepatic stellate cells and is critical in hepatic fibrosis
2003
The biology and function of fibroblasts in cancer
2016 Standout
Halofuginone to Prevent and Treat Thioacetamide–Induced Liver Fibrosis in Rats
2001
Hepatocellular carcinoma
2012 Standout
Interleukin–10 Controls Neutrophilic Infiltration, Hepatocyte Proliferation, and Liver Fibrosis Induced by Carbon Tetrachloride in Mice
1998
DLPC and SAMe prevent α1(I) collagen mRNA up-regulation in human hepatic stellate cells, whether caused by leptin or menadione
2006
Curcumin improves sclerosing cholangitis in Mdr2 −/− mice by inhibition of cholangiocyte inflammatory response and portal myofibroblast proliferation
2010
Adipogenic Transcriptional Regulation of Hepatic Stellate Cells
2004
Thiazolidinediones and PPARγ agonists: time for a reassessment
2012
Effect of adipose tissue insulin resistance on metabolic parameters and liver histology in obese patients with nonalcoholic fatty liver disease
2011
Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease
2008 Standout
Role of hydrogen peroxide and oxidative stress in healing responses
2002
Non-alcoholic fatty liver disease: The mist gradually clears
2008
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
2007 Standout
Pharmacological agents for NASH
2013
Rosiglitazone for Nonalcoholic Steatohepatitis: One-Year Results of the Randomized Placebo-Controlled Fatty Liver Improvement With Rosiglitazone Therapy (FLIRT) Trial
2008
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Fibrogenic effect of oxidative stress on rat hepatic stellate cells
1998
Regulation of PDGF and its receptors in fibrotic diseases
2004
Mechanisms of NAFLD development and therapeutic strategies
2018 Standout
Transcriptional regulation of hepatic stellate cell activation: Figure 1
2002
The metabolic syndrome
2005 Standout
Acetaldehyde Adducts in Alcoholic Liver Disease
2010
Molecular Regulation of Hepatic Fibrosis, an Integrated Cellular Response to Tissue Injury
2000 Standout
Mechanisms of Hepatic Fibrogenesis
2008 Standout
Pentoxifylline improves nonalcoholic steatohepatitis: A randomized placebo-controlled trial
2011
Long-Term Efficacy of Rosiglitazone in Nonalcoholic Steatohepatitis: Results of the Fatty Liver Improvement by Rosiglitazone Therapy (Flirt 2) Extension Trial
2009
Ethanol and Arachidonic Acid Increase α2(I) Collagen Expression in Rat Hepatic Stellate Cells Overexpressing Cytochrome P450 2E1
2000
Diabetes and Atherosclerosis
2002 Standout
The nuclear receptor SHP mediates inhibition of hepatic stellate cells by FXR and protects against liver fibrosis
2004
Iron-induced oxidant stress in alcoholic liver fibrogenesis
2003
Nonalcoholic Steatohepatitis: Summary of An Aasld Single Topic Conference
2003 Standout
Inhibition of the Na+/H+ exchanger reduces rat hepatic stellate cell activity and liver fibrosis: An in vitro and in vivo study
2001
Mechanisms and Therapy of Hepatic Fibrosis: Report of the Aasld Single Topic Basic Research Conference
2000
Pharmacological aspects of pentoxifylline with emphasis on its inhibitory actions on hepatic fibrogenesis
1997
Pioglitazone prevents hepatic steatosis, fibrosis, and enzyme-altered lesions in rat liver cirrhosis induced by a choline-deficient l-amino acid-defined diet
2004
Hepatocyte Transplantation Activates Hepatic Stellate Cells With Beneficial Modulation of Cell Engraftment in the Rat *
2005
Adipogenic Phenotype of Hepatic Stellate Cells
2005
Hydrogen peroxide: A link between acetaldehyde-elicited α1(i) collagen gene up-regulation and oxidative stress in mouse hepatic stellate cells
2000
Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial
2014 Standout
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
Free radicals and antioxidants in normal physiological functions and human disease
2006 Standout
Pioglitazone Prevents Early-Phase Hepatic Fibrogenesis Caused by Carbon Tetrachloride
2002
Effects of Sho–Saiko–To, A Japanese Herbal Medicine, on Hepatic Fibrosis in Rats
1999
Mechanisms of fibrosis: therapeutic translation for fibrotic disease
2012 Standout
Imaging Dynamic Redox Changes in Mammalian Cells with Green Fluorescent Protein Indicators
2004 StandoutNobel
PPARγ signaling and metabolism: the good, the bad and the future
2013 Standout
Modern pathogenetic concepts of liver fibrosis suggest stellate cells and TGF‐β as major players and therapeutic targets
2006
Contribution of genetics and epigenetics to progression of kidney fibrosis
2013
Risk of Cardiovascular Disease in Patients with Nonalcoholic Fatty Liver Disease
2010 Standout
Expression of Cellular Prion Protein in Activated Hepatic Stellate Cells
1998
Toxicity of hepatotoxins: new insights into mechanisms and therapy
1999
Stimulation and proliferation of primary rat hepatic stellate cells by cytochrome P450 2E1-derived reactive oxygen species
2002
Signal transduction in hepatic stellate cells
1998
PPAR-γ agonist attenuates renal interstitial fibrosis and inflammation through reduction of TGF-β
2008
Effectiveness of the PPARγ agonist, GW570, in liver fibrosis
2010
Effect of antioxidants, resveratrol, quercetin, and N -acetylcysteine, on the functions of cultured rat hepatic stellate cells and kupffer cells
1998
Rosiglitazone prevents nutritional fibrosis and steatohepatitis in mice
2008
Liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis (LEAN): a multicentre, double-blind, randomised, placebo-controlled phase 2 study
2015 Standout
Dose dependent and divergent effects of superoxide anion on cell death, proliferation, and migration of activated human hepatic stellate cells
2005
Alcoholic Liver Disease: Pathogenesis and New Therapeutic Targets
2011 Standout
Idiopathic pulmonary fibrosis
2011 Standout
Hepatocellular carcinoma pathogenesis: from genes to environment
2006 Standout
Myocardial Matrix Remodeling and the Matrix Metalloproteinases: Influence on Cardiac Form and Function
2007
Somatostatin inhibits pro‐inflammatory cytokine secretion from rat hepatic stellate cells
2005
The Na+/H+ exchanger modulates the fibrogenic effect of oxidative stress in rat hepatic stellate cells
1999
Role of SIRT1 in regulation of LPS- or two ethanol metabolites-induced TNF-α production in cultured macrophage cell lines
2009
Pioglitazone, Vitamin E, or Placebo for Nonalcoholic Steatohepatitis
2010 Standout
Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin
2003
Hepatocellular Carcinoma
2011 Standout
Antifibrotic activities of pirfenidone in animal models
2011
Chronic liver injury, TGF-β, and cancer
2001
Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver
2008 Standout
Peroxisome Proliferator-activated Receptor γ Suppresses Proximal α1(I) Collagen Promoter via Inhibition of p300-facilitated NF-I Binding to DNA in Hepatic Stellate Cells
2005
Targeting hepatic stellate cells for cell-specific treatment of liver fibrosis
2002
Aldehydes potentiate α2(I) collagen gene activity by JNK in hepatic stellate cells
2001
The Myofibroblast
2007 Standout
Caffeine Inhibits the Activation of Hepatic Stellate Cells Induced by Acetaldehyde via Adenosine A2A Receptor Mediated by the cAMP/PKA/SRC/ERK1/2/P38 MAPK Signal Pathway
2014
Liver Fibrogenesis: A New Role for the Renin–Angiotensin System
2005
The endocannabinoid 2‐arachidonoyl glycerol induces death of hepatic stellate cells via mitochondrial reactive oxygen species
2007
II. CytochromeP-450 enzymes and oxidative stress
2001
Pregnenolone-16α-carbonitrile inhibits rodent liver fibrogenesis via PXR (pregnane X receptor)-dependent and PXR-independent mechanisms
2005
Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis
2015 StandoutNobel
Improved Nonalcoholic Steatohepatitis After 48 Weeks of Treatment With the Ppar–γ Ligand Rosiglitazone
2003
Reversible Near-Infrared Fluorescent Probe Introducing Tellurium to Mimetic Glutathione Peroxidase for Monitoring the Redox Cycles between Peroxynitrite and Glutathione in Vivo
2013 Standout
Leukocytes as Modulators of Stellate Cell Activation
1999
The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases
2017 Standout
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
Mechanisms of alcohol‐induced hepatic fibrosis
2006
Catalytic Dehydrogenative Cross-Coupling: Forming Carbon−Carbon Bonds by Oxidizing Two Carbon−Hydrogen Bonds
2011 Standout
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
The selective cyclooxygenase‐2 inhibitor SC‐236 reduces liver fibrosis by mechanisms involving non‐parenchymal cell apoptosis and PPARγ activation
2005
Hepatocellular Carcinoma: Epidemiology and Molecular Carcinogenesis
2007 Standout
Cellular Mechanisms of Tissue Fibrosis. 1. Common and organ-specific mechanisms associated with tissue fibrosis
2012
Fibrosis — A Common Pathway to Organ Injury and Failure
2015 Standout
Anti‐adipogenic regulation underlies hepatic stellate cell transdifferentiation
2006
Molecular mediators of hepatic steatosis and liver injury
2004 Standout
An adipocentric view of liver fibrosis and cirrhosis.
2004
Turmeric curcumin inhibits entry of all hepatitis C virus genotypes into human liver cells
2013 StandoutNobel
Involvement of cAMP-PKA pathway in adenosine A1 and A2A receptor-mediated regulation of acetaldehyde-induced activation of HSCs
2015
Role of hepatic stellate cells in the pathogenesis of portal hypertension.
2002
Nonalcoholic Fatty Liver Disease
2015 Standout
Role of Transcriptional Factors in Stellate Cell Activation
1999
HEPATIC FIBROSIS: Molecular Mechanisms and Drug Targets
2004
Sp1 and Sp3 Transcription Factors Mediate Malondialdehyde-induced Collagen α1(I) Gene Expression in Cultured Hepatic Stellate Cells
2002
Current status of novel antifibrotic therapies in patients with chronic liver disease
2011
Works of E. Ceni being referenced
Induction of Procollagen Type I Gene Expression and Synthesis in Human Hepatic Stellate Cells by 4-Hydroxy-2,3-Nonenal and Other 4-Hydroxy-2,3-Alkenals Is Related to Their Molecular Structure
1996
Effect of pentoxifylline on the degradation of procollagen type I produced by human hepatic stellate cells in response to transforming growth factor‐β1
1997
Regulation of Undulin Synthesis and Gene Expression in Human Fat-Storing Cells by Acetaldehyde and Transforming Growth Factor-β1: Comparison with Fibronectin
1994
Peroxisome proliferator-activated receptor γ transcriptional regulation is involved in platelet-derived growth factor-induced proliferation of human hepatic stellate cells
2000
Effect of pirfenidone on rat hepatic stellate cell proliferation and collagen production
2002
Antidiabetic thiazolidinediones inhibit collagen synthesis and hepatic stellate cell activation in vivo and in vitro
2002
Oxidative stress stimulates proliferation and invasiveness of hepatic stellate cells via a MMP2‐mediated mechanism†
2005
Thiazolidinediones inhibit hepatocarcinogenesis in hepatitis B virus–transgenic mice by peroxisome proliferator‐activated receptor γ–independent regulation of nucleophosmin†
2010
Alcohol induced hepatic fibrosis: Role of acetaldehyde
2007
Acetaldehyde regulates the gene expression of matrix-metalloproteinase-1 and -2 in human fat-storing cells
1994
ACETALDEHYDE INDUCES C-FOS AND C-JUN PROTO-ONCOGENES IN FAT-STORING CELL CULTURES THROUGH PROTEIN KINASE C ACTIVATION
1994
Human hepatic stellate cells express class I alcohol dehydrogenase and aldehyde dehydrogenase but not cytochrome P4502E1
1998
Neutrophil–Derived Superoxide Anion Induces Lipid Peroxidation and Stimulates Collagen Synthesis in Human Hepatic Stellate Cells: Role of Nitric Oxide
1997