Citation Impact
Citing Papers
Extension of Murine Life Span by Overexpression of Catalase Targeted to Mitochondria
2005 StandoutScience
Parkinson-like syndrome induced by continuous MPTP infusion: Convergent roles of the ubiquitin-proteasome system and α-synuclein
2005 StandoutNobel
Mediation of Poly(ADP-Ribose) Polymerase-1-Dependent Cell Death by Apoptosis-Inducing Factor
2002 StandoutScience
Oxidative Stress and Genetics in the Pathogenesis of Parkinson's Disease
2000
Effect of MPTP on Brain Mitochondrial H2O2 and ATP Production and on Dopamine and DOPAC in the Striatum
1999
Cloning and characterization of a mammalian proton-coupled metal-ion transporter
1997 StandoutNature
Pericytes are required for blood–brain barrier integrity during embryogenesis
2010 StandoutNature
Apoptosis in the nervous system
2000 StandoutNature
Iron, Free Radicals, and Oxidative Injury
2004
Molecular identification of a renal urate–anion exchanger that regulates blood urate levels
2002 StandoutNature
NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21
2006 StandoutNature
Cleavage of BID by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis
1998 Standout
Toll‐Like Receptor 2–Deficient Mice Are Highly Susceptible toStreptococcus pneumoniaeMeningitis because of Reduced Bacterial Clearing and Enhanced Inflammation
2002
Hypertension in mice lacking the gene for endothelial nitric oxide synthase
1995 StandoutNature
Chronic Oxidative Stress as a Central Mechanism for Glucose Toxicity in Pancreatic Islet Beta Cells in Diabetes
2004
Protection from obesity-induced insulin resistance in mice lacking TNF-α function
1997 StandoutNature
Enlarged Infarcts in Endothelial Nitric Oxide Synthase Knockout Mice are Attenuated by Nitro-L-Arginine
1996
Effects of metalloporphyrin catalytic antioxidants in experimental brain ischemia
2002
Pathobiology of ischaemic stroke: an integrated view
1999 Standout
Salen- Manganese Complexes: Combined Superoxide Dismutase/Catalase Mimics with Broad Pharmacological Efficacy
1996
Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors
1996
Plasma Homocysteine as a Risk Factor for Dementia and Alzheimer's Disease
2002 Standout
Mitochondrial toxins in models of neurodegenerative diseases. I: in vivo brain hydroxyl radical production during sytemic MPTP treatment or following microdialysis infusion of methylpyridinium or azide ions
1997
Overexpression of human glutathione peroxidase protects transgenic mice against focal cerebral ischemia/reperfusion damage
1998
Nitration and Inactivation of Tyrosine Hydroxylase by Peroxynitrite
2001
Reduced Brain Edema and Infarction Volume in Mice Lacking the Neuronal Isoform of Nitric Oxide Synthase after Transient MCA Occlusion
1996
Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke
2000 Standout
Experimental models for the investigation of brain ischemia
1998
Aging, energy, and oxidative stress in neurodegenerative diseases
1995
Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress
2002 StandoutNature
The Selective Toxicity of 1-Methyl-4-phenylpyridinium to Dopaminergic Neurons: The Role of Mitochondrial Complex I and Reactive Oxygen Species Revisited
2000
Role of α-synuclein in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in mice
2003 StandoutNobel
The Molecular Genetics of Down Syndrome
1992
Plasmalemmal Vesicle Associated Protein-1 (PV-1) is a marker of blood-brain barrier disruption in rodent models
2008
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
Oxidative stress in neurodegenerative diseases: therapeutic implications for superoxide dismutase mimetics
2003
Time course and morphology of dopaminergic neuronal death caused by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
1995
Molecular Mechanisms of Ischemia–Reperfusion Injury in Brain: Pivotal Role of the Mitochondrial Membrane Potential in Reactive Oxygen Species Generation
2012
Glutathione peroxidase inhibits cell death and glial activation following experimental stroke
2002
DNA damage in brain mitochondria caused by aging and MPTP treatment
2000
Life in extreme environments
2001 StandoutNature
Superoxide dismutase, aging, and degenerative disease
1994
Lack of involvement of neuronal nitric oxide synthase in the pathogenesis of a transgenic mouse model of familial amyotrophic lateral sclerosis
1999
A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds
1993 StandoutNature
Oxidative stress in Parkinson's disease
2003 Standout
Reactive Oxygen Species in Reoxygenation Injury of Rat Brain Capillary Endothelial Cells
1998
α-Synuclein Cooperates with CSPα in Preventing Neurodegeneration
2005 StandoutNobel
Overexpression of interleukin-1 receptor antagonist in the mouse brain reduces ischemic brain injury
1997
Enhanced N-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Toxicity in Mice Deficient in CuZn-Superoxide Dismutase or Glutathione Peroxidase
2000
Increased Formation of Reactive Oxygen Species after Permanent and Reversible Middle Cerebral Artery Occlusion in the Rat
1998
Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia
1997
Midbrain dopaminergic neuronal degeneration in a transgenic mouse model of familial amyotrophic lateral sclerosis
1997
Intraluminal increase of superoxide anion following transient focal cerebral ischemia in rats
1999
Oxidants, oxidative stress and the biology of ageing
2000 StandoutNature
Pathophysiology and treatment of focal cerebral ischemia
1992
Overexpression of manganese superoxide dismutase suppresses increases in collagen accumulation induced by culture of mesangial cells in high-media glucose
2001
Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia
1994
The oxidant stress hypothesis in Parkinson's disease: Evidence supporting it
1992
Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain
1992
Benefit of vitamin E, riluzole, and gababapentin in a transgenic model of familial amyotrophic lateral sclerosis
1996
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
Biochemistry and molecular cell biology of diabetic complications
2001 StandoutNature
Biochemistry of Parkinson's disease with special reference to the dopaminergic systems
1994
Mice Deficient in Both Mn Superoxide Dismutase and Glutathione Peroxidase-1 Have Increased Oxidative Damage and a Greater Incidence of Pathology but No Reduction in Longevity
2009
The Parkinsonism-inducing Drug 1-Methyl-4-phenylpyridinium Triggers Intracellular Dopamine Oxidation
2000
Inhibition of neuronal nitric oxide synthase prevents MPTP–induced parkinsonism in baboons
1996
Reperfusion following focal cerebral ischemia alters distribution of neuronal cells with DNA fragmentation in mice
1997
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Increased susceptibility to MPTP toxicity in middle-aged rhesus monkeys
1995
Homeostasis in Mice with Genetically Decreased Angiotensinogen Is Primarily by an Increased Number of Renin-producing Cells
1999 StandoutNobel
The Hallmarks of Aging
2013 Standout
Visualizing Superoxide Production in Normal and Diabetic Rat Islets of Langerhans
2003
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Oxidative stress and nitration in neurodegeneration: Cause, effect, or association?
2003
Prion Protein-Deficient Cells Show Altered Response to Oxidative Stress Due to Decreased SOD-1 Activity
1997
Increased nitrotyrosine immunoreactivity in substantia nigra neurons in MPTP treated baboons is blocked by inhibition of neuronal nitric oxide synthase
1999
Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC
1999 StandoutNature
Manganese Superoxide Dismutase Overexpression Attenuates MPTP Toxicity
1998
Peroxynitrite Formed by Simultaneous Nitric Oxide and Superoxide Generation Causes Cyclosporin‐A‐Sensitive Mitochondrial Calcium Efflux and Depolarisation
1995
Iron‐sulfur enzyme mediated mitochondrial superoxide toxicity in experimental Parkinson's disease
2004
Genetics of aging: Current animal models
1996
Oxidative stress in Parkinson's disease
1995
Pathogen Recognition and Innate Immunity
2006 Standout
Anemia of Chronic Disease
2005 Standout
Parkinson's Disease
2003 Standout
Oxidative Decay of DNA
1997
Cerebral vessels express interleukin 1β after focal cerebral ischemia
1998
Prolyl Hydroxylase Domain Inhibitors: A Route to HIF Activation and Neuroprotection
2009
Peroxynitrite-Mediated Protein Nitration and Lipid Peroxidation in a Mouse Model of Traumatic Brain Injury
2004
Prorenin and Other Large Molecular Weight Forms of Renin*
1980
Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage
1999 StandoutNobel
Levodopa-Induced Neurotoxicity
1997
BCL-2 GENE FAMILY IN THE NERVOUS SYSTEM
1997
Oxidants, antioxidants, and the degenerative diseases of aging.
1993 Standout
Mitochondrial Susceptibility to Oxidative Stress Exacerbates Cerebral Infarction That Follows Permanent Focal Cerebral Ischemia in Mutant Mice with Manganese Superoxide Dismutase Deficiency
1998
Blockade of Microglial Activation Is Neuroprotective in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Mouse Model of Parkinson Disease
2002
Interaction of chlamydiae and host cells in vitro
1991
An α-syntrophin-dependent pool of AQP4 in astroglial end-feet confers bidirectional water flow between blood and brain
2003 StandoutNobel
A Reproducible Model of Middle Cerebral Artery Occlusion in Mice: Hemodynamic, Biochemical, and Magnetic Resonance Imaging
1998
The Free Radical Theory of Aging Matures
1998 Standout
Overexpression of SOD1 in Transgenic Rats Protects Vulnerable Neurons Against Ischemic Damage After Global Cerebral Ischemia and Reperfusion
1998
Ischemic Delayed Neuronal Death
1995
The 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model: a tool to explore the pathogenesis of Parkinson's disease.
2003
Induction of DNA Fragmentation After 10 to 120 Minutes of Focal Cerebral Ischemia in Rats
1995
Manganese Superoxide Dismutase Deficiency Exacerbates Cerebral Infarction After Focal Cerebral Ischemia/Reperfusion in Mice
2002
Reperfusion-Induced Oxidative/Nitrative Injury to Neurovascular Unit After Focal Cerebral Ischemia
2004
The 1‐Methyl‐4‐Phenyl‐1,2,3,6‐Tetrahydropyridine Mouse Model
2003
Role of Oxidants in Ischemic Brain Damage
1996
Extracellular superoxide dismutase deficiency worsens outcome from focal cerebral ischemia in the mouse
1999
Inactivation of tyrosine hydroxylase by nitration following exposure to peroxynitrite and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)
1998
Mitochondrial Manganese Superoxide Dismutase Prevents Neural Apoptosis and Reduces Ischemic Brain Injury: Suppression of Peroxynitrite Production, Lipid Peroxidation, and Mitochondrial Dysfunction
1998
Ubiquitous overexpression of CuZn superoxide dismutase does not extendlife span in mice
2000
NADPH oxidase mediates oxidative stress in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease
2003
Oxidative stress and nitration in neurodegeneration: Cause, effect, or association?
2003
Reduced Ischemic Brain Injury in Interleukin-1β Converting Enzyme—Deficient Mice
1998
Effect of overexpression of wild‐type and mutant Cu/Zn‐superoxide dismutases on oxidative stress and cell death induced by hydrogen peroxide, 4‐hydroxynonenal or serum deprivation: potentiation of injury by ALS‐related mutant superoxide dismutases and protection by Bcl‐2
2001
Double-knockout mice for α- and β-synucleins: Effect on synaptic functions
2004 StandoutNobel
Mice Deficient in Interleukin-1 Converting Enzyme are Resistant to Neonatal Hypoxic-Ischemic Brain Damage
1999
Prions
1998 StandoutNobel
Mitochondrial Dysfunction and Type 2 Diabetes
2005 StandoutScience
ARL 17477, a Potent and Selective Neuronal NOS Inhibitor Decreases Infarct Volume after Transient Middle Cerebral Artery Occlusion in Rats
1996
The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer’s and Parkinson’s diseases1,2 11Guest Editors: Mark A. Smith and George Perry 22This article is part of a series of reviews on “Causes and Consequences of Oxidative Stress in Alzheimer’s Disease.” The full list of papers may be found on the homepage of the journal.
2002
Cytosolic Redistribution of Cytochrome C after Transient Focal Cerebral Ischemia in Rats
1998
Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery
1997 Standout
Ischemic Cell Death in Brain Neurons
1999 Standout
Manganese Superoxide Dismutase Mediates the Early Release of Mitochondrial Cytochrome C and Subsequent DNA Fragmentation after Permanent Focal Cerebral Ischemia in Mice
1999
Effects of Cerebral Ischemia in Mice Deficient in Neuronal Nitric Oxide Synthase
1994 Science
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyride Neurotoxicity Is Attenuated in Mice Overexpressing Bcl-2
1998
Induction of α-Synuclein Aggregation by Intracellular Nitrative Insult
2001
Reactive Oxygen Species in Metabolic and Inflammatory Signaling
2018 Standout
Impaired Degradation of Mutant α-Synuclein by Chaperone-Mediated Autophagy
2004 StandoutScience
Delayed Reduction of Ischemic Brain Injury and Neurological Deficits in Mice Lacking the Inducible Nitric Oxide Synthase Gene
1997
Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity.
1996
Resistance to neurotoxicity in cortical cultures from neuronal nitric oxide synthase-deficient mice
1996
Overexpression of Copper-Zinc Superoxide Dismutase Attenuates Acute Activation of Activator Protein-1 After Transient Focal Cerebral Ischemia in Mice
2001
Oxidative Stress, Glutamate, and Neurodegenerative Disorders
1993 StandoutScience
Delayed onset of brain edema and mislocalization of aquaporin-4 in dystrophin-null transgenic mice
2002 StandoutNobel
N-tert-butyl-alpha-phenylnitrone improves recovery of brain energy state in rats following transient focal ischemia.
1995
Distinct Mechanisms Underlie Neurotoxin-Mediated Cell Death in Cultured Dopaminergic Neurons
1999
Mutations in the DJ-1 Gene Associated with Autosomal Recessive Early-Onset Parkinsonism
2003 StandoutScience
Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism
1999
Aquaporin-4 square array assembly: Opposing actions of M1 and M23 isoforms
2003 StandoutNobel
Inhibition of NADPH Oxidase is Neuroprotective after Ischemia—Reperfusion
2009
Reduction of CuZn-Superoxide Dismutase Activity Exacerbates Neuronal Cell Injury and Edema Formation after Transient Focal Cerebral Ischemia
1997
Mechanisms and Genes of Cellular Suicide
1995 StandoutScience
Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing CuZn superoxide dismutase.
1991
The Transcription Factor Interferon Regulatory Factor 1 Is Expressed after Cerebral Ischemia and Contributes to Ischemic Brain Injury
1999
Oxidative stress in neurodegeneration: cause or consequence?
2004 Standout
Genome Sequence of an Obligate Intracellular Pathogen of Humans: Chlamydia trachomatis
1998 StandoutScience
Peroxynitrite decomposition catalysts: Therapeutics for peroxynitrite-mediated pathology
1998
Works of E. Carlson being referenced
SOD‐1 Transgenic Mice as a Model for Studies of Neuroprotection in Stroke and Brain Traumaa
1994
Cold‐induced brain edema and infarction are reduced in transgenic mice overexpressing CuZn‐Superoxide dismutase
1991
Superoxide Dismutase, Catalase, and Glutathione Peroxidase Activities in Copper/Zinc‐Superoxide Dismutase Transgenic Mice
1992
Chapter 6 Role of superoxide dismutase in ischemic brain injury: reduction of edema and infarction in transgenic mice following focal cerebral ischemia
1993
Edema Formation Exacerbates Neurological and Histological Outcomes After Focal Cerebral Ischemia in CuZn-Superoxide Dismutase Gene Knockout Mutant Mice
1997
Transgenic Mice and Knockout Mutants in the Study of Oxidative Stress in Brain Injury
1995
Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity
1992
Protective role of magnesium in the neutralization by antibodies of Chlamydia trachomatis infectivity
1988
Neuroprotective role of CuZn-superoxide dismutase in ischemic brain damage.
1996
Human copper-zinc superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia.
1994
Transgenic copper/zinc superoxide dismutase modulates susceptibility to type I diabetes.
1994
A Comparison of Cold and Acid Activation of Big Renin and of Inactive Renin in Normal Plasma*
1978